GSE48125: Neonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates

  • Denise Kelly (Creator)
  • Imke Elisabeth Mulder (Creator)
  • Peter Morgan (Data Manager)

Dataset

Description

Expression profiling by array

Caesarean-delivered preterm pigs were fed 3 d of parenteral nutrition followed by 2 d of enteral formula feeding. Antibiotics (n=11) or control saline (n=13) were given twice daily from birth to tissue collection at d 5. NEC-lesions and intestinal structure, function, microbiology and immunity markers were recorded.
We used Affymetrix microarrays to investigate gene expression in intestinal tissues of preterm piglets treated with antibiotics or control saline.
Date made available21 Aug 2013
PublisherGEO

Research Output

Antibiotics modulate intestinal immunity and prevent necrotizing enterocolitis in preterm neonatal piglets

Jensen, M. L., Thymann, T., Cilieborg, M. S., Lykke, M., Mølbak, L., Jensen, B. B., Schmidt, M., Kelly, D., Mulder, I., Burrin, D. G. & Sangild, P. T., Jan 2014, In : American journal of physiology. Gastrointestinal and liver physiology . 306, 1, p. G59-G71 13 p.

Research output: Contribution to journalArticle

  • 47 Citations (Scopus)

    Cite this

    Kelly, D. (Creator), Mulder, I. E. (Creator), Morgan, P. J. (Data Manager) (21 Aug 2013). GSE48125: Neonatal antibotic prophylaxis modulates intestinal immunity and prevents necrotizing enterocolitis in preterm neonates . GEO.