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2020

1H spin-lattice NMR relaxation in the presence of residual dipolar interactions: Dipolar Relaxation

Kruk, D., Rochowski, P., Florek-Wojciechowska, M., Sebastiao, P., Lurie, D. & Broche, L., 5 Jul 2020, (Accepted/In press) In : Journal of Magnetic Resonance.

Research output: Contribution to journalArticle

A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization

Kiel, C., Berber, P., Karlstetter, M., Aslanidis, A., Strunz, T., Langmann, T., Grassmann, F. & Weber, B. H. F., Apr 2020, In : International Journal of Molecular Sciences. 21, 8, 2689.

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Agricultural intensification and the evolution of host specialism in the enteric pathogen Campylobacter jejuni

Mourkas, E., Taylor, A. J., Méric, G., Bayliss, S. C., Pascoe, B., Mageiros, L., Calland, J. K., Hitchings, M. D., Ridley, A., Vidal, A., Forbes, K. J., Strachan, N. J. C., Parker, C. T., Parkhill, J., Jolley, K. A., Cody, A. J., Maiden, M. C. J., Kelly, D. J. & Sheppard, S. K., 19 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 20, p. 11018-11028 11 p.

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Anaemia and incidence of post stroke dementia

Myint, P. K., Macleod, M. J., Clark, A. B., Smith, T. O., Bettencourt-Silva, J. H., Metcalf, A. K. & Potter, J. F., Apr 2020, In : Clinical Neurology and Neurosurgery. 191, 105688.

Research output: Contribution to journalArticle

Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

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A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

Westbury, S. K., Whyte, C. S., Stephens, J., Downes, K., Turro, E., Claesen, K., Mertens, J. C., Hendriks, D., Latif, AL., Leishman, E. J., NIHR BioResource, Mutch, N. J., Campbell Tait, R. & Mumford, A. D., 23 Jul 2020, In : Journal of Thrombosis and Haemostasis. 6 p.

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A novel 4-dimensional live-cell imaging system to study leukocyte-endothelial dynamics in ANCA-associated vasculitis

Walls, C. A., Basu, N., Hutcheon, G., Erwig, L. P., Little, M. A. & Kidder, D., 2020, In : Autoimmunity. 53, 3, p. 148-155 8 p.

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1 Citation (Scopus)

An overview of prevalence, determinants and health outcomes of polypharmacy

Khezrian, M., McNeil, C. J., Murray, A. D. & Myint, P. K., 12 Jun 2020, In : Therapeutic Advances in Drug Safety. 11, p. 1-10 10 p.

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Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., May 2020, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 156, 10 p., 102024.

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3 Citations (Scopus)
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Anticholinergic Burden Measures Predict Older People’s Physical Function and Quality of Life: A Systematic Review

Stewart, C., Yrjana, K., Kisshor, M., Soiza, R. L., Taylor-Rowan, M., Quinn, T. J., Loke, Y. K. & Myint, P. K., 21 Jul 2020, In : Journal of the American Medical Directors Association.

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A sensorimotor control framework for understanding emotional communication and regulation.

Williams, J. H. G., Huggins, C. F., Zupan, B., Willis, M., Van Rheenen, T. E., Sato, W., Palermo, R., Ortner, C., Krippl, M., Kret, M., Dickson, J. M., Li, C-S. R. & Lowe, L., 2020, In : Neuroscience & Biobehavioral Reviews. 112, p. 503-518 16 p.

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Assessing Risks of Polypharmacy Involving Medications With Anticholinergic Properties

Hanlon, P., Quinn, T. J., Gallacher, K., Myint, P. K., Jani, B. D., Nicholl, B. I., Lowrie, R., Soiza, R. L., Neal, S. R., Lee, D. & Mair, F., 31 Mar 2020, In : Annals of Family Medicine. 18, 2, p. 148-155 8 p.

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1 Citation (Scopus)

Association of Inflammation With Pronociceptive Brain Connections in Rheumatoid Arthritis Patients With Concomitant Fibromyalgia

Kaplan, C. M., Schrepf, A., Ichesco, E., Larkin, T., Harte, S. E., Harris, R. E., Murray, A. D., Waiter, G. D., Clauw, D. J. & Basu, N., Jan 2020, In : Arthritis & Rheumatology. 72, 1, p. 41-46 6 p.

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1 Citation (Scopus)
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A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), 31 Jan 2020, In : Scientific Reports. 10, 16 p., 1584.

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A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In : Microorganisms. 8, 7, 14 p., 1066.

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Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression

Rupprechter, S., Romaniuk, L., Series, P., Hirose, T., Hawkins, E., Sandu-Giuraniuc, A-L., Waiter, G. D., McNeil, C. J., Shen, X., Harris, M. A., Campbell, A., Porteous, D., Macfarlane, J. A., Lawrie, S. M., Murray, A. D., Delgado, M. R., McIntosh, A. M., Whalley, H. C. & Steele, J. D., Jun 2020, In : Brain. 143, 6, p. 1946-1956 11 p.

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Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

Varsou, O., Macleod, M. J., Schwarzbauer, C., Murray, A. D., Dinis Fernandes, C., Stringer, M. S. & Turnbull, K., Jun 2020, In : Neurological Sciences. 41, 6, p. 1633-1635 3 p.

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Brainstem volume mediates seasonal variation in depressive symptoms: A cross sectional study in the UK Biobank cohort

Majrashi, N. A., Ahearn, T. S. & Waiter, G. D., 27 Feb 2020, In : Scientific Reports. 10, 3592.

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Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., Apr 2020, In : Archives of Toxicology. 94, p. 1241-1250 10 p.

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CFTR modulators dampen Aspergillus-induced reactive oxygen species production by cystic fibrosis phagocytes

Currie, A. J., Main, E. T., Wilson, H. M., Armstrong-James, D. & Warris, A., 24 Jul 2020, In : Frontiers in cellular and infection microbiology. 10, 11 p., 372.

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Changing fish distributions challenge the effective management of European fisheries

Baudron, A. R., Brunel, T., Blanchet, M-A., Hidalgo, M., Chust, G., Brown, E., Kleisner, K. M., Millar, C., MacKenzie, B. R., Nikolioudakis, N., Fernandes, J. & Fernandes, P. G., Apr 2020, In : Ecography. 43, 4, p. 494-505 12 p.

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Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 2020, In : Brain Communications. 2, 1, 17 p., fcaa033.

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Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis: The BiCARB randomised controlled trial

Witham, M. D., Band, M., Chong, H. Y., Donnan, P. T., Hampson, G., Hu, M. K., Littleford, R., Lamb, E., Kalra, P., Kennedy, G., McNamee, P., Plews, D., Rauchhaus, P., Soiza, R. L., Sumukadas, D., Warwick, G. & Avenell, A., 25 Feb 2020, (Accepted/In press) In : Health Technology Assessment.

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Clinical effectiveness of pharmacist-led versus conventionally delivered antiviral treatment for hepatitis C virus in patients receiving opioid substitution therapy: A pragmatic cluster randomised trial

Radley, A., de Bruin, M., Inglis, S. K., Donnan, P. T., Hapca, A., Barclay, S. T., Fraser, A. & Dillon, J. F., 8 Jun 2020, In : The Lancet Gastroenterology & Hepatology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial

Liao, D. S., Grossi, F. V., El Mehdi, D., Gerber, M. R., Brown, D. M., Heier, J. S., Wykoff, C. C., Singerman, L. J., Abraham, P., Grassmann, F., Nuernberg, P., Weber, B. H. F., Deschatelets, P., Kim, R. Y., Chung, C. Y., Ribeiro, R. M., Hamdani, M., Rosenfeld, P. J., Boyer, D. S., Slakter, J. S. & 1 others, Francois, C. G., Feb 2020, In : Ophthalmology. 127, 2, p. 186-195 10 p.

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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

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Correlation Between the Total Small Bowel Length and Anthropometric Measures in Living Humans: Cross-Sectional Study

Bekheit, M., Ibrahim, M. Y., Tobar, W., Galal, I. & Elward, A. S., Feb 2020, In : Obesity Surgery. 30, p. 681-686 6 p.

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Current concepts in tumour-derived organoids

Porter, R. J., Murray, G. & McLean, M. H., 30 Jul 2020, In : British Journal of Cancer.

Research output: Contribution to journalArticle

CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer

He, W., Grassmann, F., Eriksson, M., Eliasson, E., Margolin, S., Thorén, L., Hall, P. & Czene, K., 20 Feb 2020, In : Journal of Clinical Oncology. 38, 6, p. 548-557 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

Moore, H., Gando, S., Iba, T., Kim, P. Y., Yeh, C. H., Brohi, K., Hunt, B. J., Levy, J. H., Draxler, D. F., Stanworth, S. J., Görlinger, K., Neal, M. D., Schreiber, M. A., Barrett, C. D., Medcalf, R. L., Moore, E. E., Mutch, N. J., Thachil, J., Urano, T., Thomas, S. & 2 others, Scărlătescu, E. & Walsh, M., Mar 2020, In : Journal of Thrombosis and Haemostasis. 18, 3, p. 740-747 8 p.

Research output: Contribution to journalArticle

Delirium screening in the intensive care unit using emerging QEEG techniques: A pilot study

Hunter, A., Crouch, B., Webster, N. & Platt, B., 13 Jan 2020, In : AIMS Neuroscience. 7, 1, p. 1-16 16 p.

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Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 9 Jul 2020, In : ChemMedChem. 13 p.

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4 Citations (Scopus)
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Does prior antithrombotic therapy influence stroke recurrence and bleeding risk in patients with atrial fibrillation and flutter?

Gamble, D. T., Buono, R., Mamas, M. A., Leslie, S., Bettencourt-Silva, J. H., Clark, A. B., Bowles, K. M., Metcalf, A. K., Potter, J. F. & Myint, P. K., 1 May 2020, In : European Journal of Preventive Cardiology. 27, 7, p. 729-737 9 p.

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Does quality of care in hip fracture vary by day of admission?

Farrow, L., Hall, A., Aucott, L., Holt, G. & Myint, P. K., 20 Mar 2020, In : Archives of Osteoporosis. 15, 52.

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Dynamics of the transcriptional landscape during human fetal testis and ovary development

Lecluze, E., Rolland, A. D., Filis, P., Evrard, B., Leverrier-Penna, S., Ben Maamar, M., Coiffec, I., Lavoué, V., Fowler, P. A., Mazaud Guittot, S., Jégou, B. & Chalmel, F., May 2020, In : Human Reproduction. 35, 5, p. 1099-1119 21 p.

Research output: Contribution to journalArticle

Efficacy of daratumumab combination regimen in patients with multiple myeloma: A combined analysis of phase III randomized controlled trials

Htut, T. W., Thein, K. Z., Lawrie, A., Tighe, J. & Preston, G., 23 Jun 2020, In : eJHaem.

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Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

Kleeman, S. O., Koelzer, V. H., Jones, H. J. S., Vazquez, E. G., Davis, H., East, J. E., Arnold, R., Koppens, M. A. J., Blake, A., Domingo, E., Cunningham, C., Beggs, A. D., Pestinger, V., Loughrey, M. B., Wang, L-M., Lannagan, T. R. M., Woods, S. L., Worthley, D., The S:CORT Consortium, Tomlinson, I. & 3 others, Dunne, P. D., Maughan, T. & Leedham, S. J., 2020, In : Gut. 69, p. 1092-1103 12 p.

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Expression of the Insulin-like Growth Factor system in first and second trimester human embryonic and fetal gonads

Mamsen, L. S., Zafeiri, A., Bøtkjær, J. A., Rasmussen, J. H., Ernst, E., Oxvig, C., Fowler, P. A. & Andersen, C. Y., 29 Jul 2020, In : Journal of Clinical Endocrinology and Metabolism.

Research output: Contribution to journalArticle

Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery

Kaira, B., Slater, A., McCrae, K., Dreveny, I., Ummay, S., Mutch, N., Searle, M. & Emsley, J., 19 Jun 2020, In : Blood.

Research output: Contribution to journalArticle