Research Output

2020

A comparison of the beta-geometric model with landmarking for dynamic prediction of time to pregnancy

van Eekelen, R., Putter, H., McLernon, D. J., Eijkemans, M. J. & van Geloven, N., Jan 2020, In : Biometrical Journal. 62, 1, p. 175-190 16 p.

Research output: Contribution to journalArticle

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Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

Research output: Contribution to journalArticle

Association of Inflammation With Pronociceptive Brain Connections in Rheumatoid Arthritis Patients With Concomitant Fibromyalgia

Kaplan, C. M., Schrepf, A., Ichesco, E., Larkin, T., Harte, S. E., Harris, R. E., Murray, A. D., Waiter, G. D., Clauw, D. J. & Basu, N., Jan 2020, In : Arthritis & Rheumatology. 72, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Asthma in Children and Adults – What Are The Differences and What Can They Tell Us About Asthma? Editorial

Turner, S. & Upham, J. W., 11 Mar 2020, (Accepted/In press) In : Frontiers in pediatrics.

Research output: Contribution to journalEditorial

Open Access

Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

Varsou, O., Macleod, M. J., Schwarzbauer, C., Murray, A. D., Dinis Fernandes, C., Stringer, M. S. & Turnbull, K., 23 Jan 2020, In : Neurological Sciences. 3 p.

Research output: Contribution to journalArticle

Open Access

Cancer diagnosis in Scottish primary care: Results from the National Cancer Diagnosis Audit

Murchie, P., Adam, R., McNair, E., Swann, R., Witt, J., Wood, R. & Weller, D., 10 Mar 2020, In : European Journal of Cancer Care.

Research output: Contribution to journalArticle

Characterizing infection in anti-neutrophil cytoplasmic antibody-associated vasculitis: results from a longitudinal, matched-cohort data linkage study

Sarica, S. H., Dhaun, N., Sznajd, J., Harvie, J., McLaren, J., McGeoch, L., Kumar, V., Amft, N., Erwig, L., Marks, A., Black, C. & Basu, N., 11 Mar 2020, In : Rheumatology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Open Access
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Cohort profile: The prospective study on Chinese elderly with multimorbidity in primary care in Hong Kong

Zhang, D., Sit, R. W. S., Wong, C., Zou, D., Mercer, S. W., Johnston, M. C. & Wong, S. Y. S., Feb 2020, In : BMJ Open. 10, 2, 17 p., e027279.

Research output: Contribution to journalArticle

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Concentration-dependent activity of hydromethylthionine on clinical decline and brain atrophy in a randomized controlled trial in behavioural variant frontotemporal dementia (bvFTD)

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 4 Mar 2020, (Accepted/In press) In : Journal of Alzheimer's Disease.

Research output: Contribution to journalArticle

Does treatment guided by fractional exhaled nitric oxide improve outcomes in subgroups of children with asthma?

Fielding, S., Pijnenburg, M. W., de Jongste, J. C., Pike, K., Roberts, G., Petsky, H., Chang, A. B., Fritsch, M., Frischer, T., Szefler, S. J., Gergen, P., Vermeulen, F., Vael, R. & Turner, S., 12 Mar 2020, In : European Respiratory Journal.

Research output: Contribution to journalArticle

Effect of a Skin Self-Monitoring Smart Phone Application on Time to Consultation With Physician Among Patients With Possible Melanoma: A Phase II randomized clinical trial

Walter, F. M., Pannebakker, M. M., Barclay, M. E., Mills, K., Saunders, C. L., Murchie, P., Corrie, P., Hall, P., Burrows, N. & Emery, J., Feb 2020, In : JAMA Network Open. 3, 2, 13 p., e200001.

Research output: Contribution to journalArticle

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Game of Stones: feasibility randomised controlled trial of how to engage men with obesity in text message and incentive interventions for weight loss

Dombrowski, S. U., McDonald, M., van der Pol, M., Grindle, M., Avenell, A., Carroll, P., Calveley, E., Elders, A., Glennie, N., Gray, C. M., Harris, F. M., Hapca, A., Jones, C., Kee, F., McKinley, M. C., Skinner, R., Tod, M. & Hoddinott, P., 2020, In : BMJ Open. 10, 2, 032653.

Research output: Contribution to journalArticle

Open Access
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Impact of Geography on Scottish Cancer Diagnoses in Primary Care: Results from a National Cancer Diagnosis Audit

Murchie, P., Adam, R., Khor, W. L., Smith, S., McNair, E., Swann, R., Witt, J. & Weller, D., 28 Mar 2020, (Accepted/In press) In : Cancer Epidemiology.

Research output: Contribution to journalArticle

Incidence of paediatric unplanned day-case admissions in the UK and Ireland: a prospective multicentre observational study

Paediatric Anaesthesia Trainee Research Network, Apr 2020, In : British Journal of Anaesthesia. 124, 4, p. 463-472 10 p.

Research output: Contribution to journalArticle

Influences of rurality on action to diagnose cancer by primary care practitioners– results from a Europe-wide survey in 20 countries

Murchie, P., Khor, W. L., Adam, R., Esteva, M., Smyrnakis, E., Petek, D., Thulesius, H., Vedsted, P., McLernon, D. & Harris, M., Apr 2020, In : Cancer Epidemiology. 65, 101698.

Research output: Contribution to journalArticle

Klotho gene polymorphism, brain structure and cognition in early-life development

de Vries, C. F., Staff, R., Noble, K. G., Muetzel, R. L., Vernooij, M. W., White, T., Waiter, G. D. & Murray, A. D., 2020, In : Brain Imaging and Behavior. 14, p. 213-225 13 p.

Research output: Contribution to journalArticle

Open Access
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Motion during Acquisition is Associated with fMRI Brain Entropy

de Vries, C., Staff, R. T., Waiter, G. D., Sokunbi, M. O., Sandu, A. L. & Murray, A. D., Feb 2020, In : IEEE journal of biomedical and health informatics. 24, 2, p. 586-593 8 p.

Research output: Contribution to journalArticle

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Ocrelizumab for Treating Patients with Primary Progressive Multiple Sclerosis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal

Auguste, P., Colquitt, J., Connock, M., Loveman, E., Court, R., Ciccarelli, O., Counsell, C. & Armoiry, X., 12 Feb 2020, In : Pharmacoeconomics.

Research output: Contribution to journalReview article

Patterns of symptoms possibly indicative of cancer and associated help-seeking behaviour in a large sample of United Kingdom residents: the USEFUL study

Hannaford, P. C., Thornton, A. J., Murchie, P., Whitaker, K. L., Adam, R. & Elliott, A. M., 24 Jan 2020, In : PloS ONE. 15, 1, e0228033.

Research output: Contribution to journalArticle

Open Access
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Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation

King, C., McKenna, A., Farzan, N., Vijverberg, S. J., van der Schee, M. P., Maitland-van der Zee, A. H., Arianto, L., Bisgaard, H., BØnnelykke, K., Berce, V., Potočnik, U., Repnik, K., Carleton, B., Daley, D., Chew, F. T., Chiang, W. C., Sio, Y. Y., Cloutier, M. M., Den Dekker, H. T., Duijts, L. & 16 others, de Jongste, J. C., Dijk, F. N., Koppelman, G. H., Flores, C., Hernandez-Pacheco, N., Pino-Yanes, M., Mukhopadhyay, S., Basu, K., Bignell, L., Tantisira, K. G., Turner, S., Verhamme, K. M., Francis, B., Pirmohamed, M., Sinha, I. & Hawcutt, D. B., 17 Jan 2020, In : Pharmacogenomics Journal. 8 p.

Research output: Contribution to journalReview article

Open Access
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Reconceptualising Rural Cancer Inequalities: Time for a New Research Agenda

Dobson, C., Rubin, G., Murchie, P., Macdonald, S. & Sharp, L., 24 Feb 2020, In : International Journal of Environmental Research and Public Health. 17, 4, 1455.

Research output: Contribution to journalArticle

Open Access
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Risk factors associated with biochemically detected and hospitalised acute kidney injury in patients prescribed renin angiotensin system inhibitors

Mark, P. B., Papworth, R., Ramparsad, N., Tomlinson, L., Sawhney, S., Black, C., McConnachie, A. & McCowan, C., Jan 2020, In : British Journal of Clinical Pharmacology. 86, 1, p. 121-131 11 p.

Research output: Contribution to journalArticle

Statin use and risk of liver cancer: Evidence from two population-based studies

Tran, K. T., McMenamin, Ú. C., Coleman, H. G., Cardwell, C. R., Murchie, P., Iversen, L., Lee, A. J. & Thrift, A. P., 1 Mar 2020, In : International Journal of Cancer. 146, 5, p. 1250-1260 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The role of 5α‐reductase inhibitors in gastro‐oesophageal cancer risk: A nested case‐control study

Busby, J., Karasneh, R., Murchie, P., McMenamin, Ú., Gadalla, S. M., Camargo, M. C., Iversen, L., Lee, A. J., Spence, A. D. & Cardwell, C. R., Jan 2020, In : Pharmacoepidemiology and Drug Safety. 29, 1, p. 48-56 9 p.

Research output: Contribution to journalArticle

Use of proton pump inhibitors and histamine-2 receptor antagonists and risk of gastric cancer in two population-based studies

Liu, P., McMenamin, Ú. C., Johnston, B. T., Murchie, P., Iversen, L., Lee, A., Vissers, P. A. J. & Cardwell, C. R., 25 Mar 2020, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

2019

27 years of prenatal diagnosis for Huntington disease in the United Kingdom

Piña-Aguilar, R. E., Simpson, S. A., Alshatti, A., Clarke, A., Craufurd, D., Dorkins, H., Doye, K., Lahiri, N., Lashwood, A., Lynch, C., Miller, C., Morton, S., O’Driscoll, M., Quarrell, O. W., Rae, D., Strong, M., Tomlinson, C., Turnpenny, P., Miedzybrodzka, Z. & UK HD Predictive Testing Consortium, Jul 2019, In : Genetics in Medicine. 21, p. 1639–1643 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A case-note review of continued pregnancies found to be at a high risk of Huntington’s disease: considerations for clinical practice

Wadrup, F., Holden, S., MacLeod, R., Miedzybrodzka, Z., Németh, A. H., Owens, S., Pasalodos, S., Quarrell, O., Clarke, A. J. & on behalf of the UK Huntington’s Disease Predictive Testing Consortium, 19 Mar 2019, In : European Journal of Human Genetics. 27, p. 1215-1224 10 p.

Research output: Contribution to journalArticle

Open Access
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A comparison of professional and private time preferences of General Practitioners

Irvine, A., Van der Pol, M. & Phimister, E., 1 Feb 2019, In : Social Science & Medicine. 222, p. 256-264 9 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

A meta-analysis of genome-wide association studies of epigenetic age acceleration

Gibson, J., Russ, T. C., Clarke, T-K., Howard, D. M., Hillary, R. F., Evans, K. L., Walker, R. M., Bermingham, M. L., Morris, S. W., Campbell, A., Hayward, C., Murray, A. D., Porteous, D. J., Horvath, S., Lu, A. T., McIntosh, A. M., Whalley, H. C. & Marioni, R. E., Nov 2019, In : PLoS Genetics. 15, 11, e1008104.

Research output: Contribution to journalArticle

Open Access
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An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort

Kerr, S. M., Klaric, L., Halachev, M., Hayward, C., Boutin, T. S., Meynert, A. M., Semple, C. A., Tuiskula, A. M., Swan, H., Santoyo-Lopez, J., Vitart, V., Haley, C., Dean, J., Miedzybrodzka, Z., Aitman, T. J. & Wilson, J. F., 29 Jul 2019, In : Scientific Reports. 9, 11 p., 10964.

Research output: Contribution to journalArticle

Open Access
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An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity. 43, p. 1795-1802 8 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
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An epigenome-wide association study of sex-specific chronological ageing

McCartney, D. L., Zhang, F., Hillary, R. F., Zhang, Q., Stevenson, A. J., Walker, R. M., Bermingham, M. L., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Evans, K. L., Chandra, T., Deary, I. J., McIntosh, A. M., Yang, J., Visscher, P. M., McRae, A. F. & Marioni, R. E., 31 Dec 2019, In : Genome Medicine. 12, 1.

Research output: Contribution to journalArticle

Open Access
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Open Access
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Open Access
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Open Access
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1 Citation (Scopus)

Associations of autozygosity with a broad range of human phenotypes

Murray, A. D., Clark, D. W., Yukinori, O., Kristjan H S, M., Mason, D., Pirastu, N. N. & consortium, ROH., 31 Oct 2019, In : Nature Communications. 10, 4957.

Research output: Contribution to journalArticle

Open Access
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Asthma causation and the gastrointestinal microbiome and metabolome: Might there be a signal, or is it just noise?

Hansen, R., Gerasimidis, K. & Turner, S., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 401-403 3 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements

Huang, I., Mak, D., Cheung, P., Abraham, M., Clemens, T. & Turner, S., Jun 2019, In : Environmental Research. 173, p. 528-538 11 p.

Research output: Contribution to journalArticle

Calibration: the Achilles heel of predictive analytics

Topic Group ‘Evaluating diagnostic tests and prediction models’ of the STRATOS initiative, 16 Dec 2019, In : BMC medicine . 17, 230.

Research output: Contribution to journalArticle

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Can we understand and improve poorer cancer survival in rural-dwellers?

Murchie, P., Adam, R., Wood, R. & Fielding, S., Jul 2019, In : BJGP Open. 3, 2, 4 p., bjgpopen19X101646.

Research output: Contribution to journalArticle

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Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies

Coresh, J., Heerspink, H. J. L., Sang, Y., Matsushita, K., Arnlov, J., Astor, B. C., Black, C., Brunskill, N. J., Carrero, J-J., Feldman, H. I., Fox, C. S., Inker, L. A., Ishani, A., Ito, S., Jassal, S., Konta, T., Polkinghorne, K., Romundstad, S., Solbu, M. D., Stempniewicz, N. & 12 others, Stengel, B., Tonelli, M., Umesawa, M., Waikar, S. S., Wen, C-P., Wetzels, J. F. M., Woodward, M., Grams, M. E., Kovesdy, C. P., Levey, A. S., Gansevoort, R. T. & Chronic Kidney Disease Prognosis Consortium and Chronic Kidney Disease Epidemiology Collaboration, Feb 2019, In : The lancet. Diabetes & endocrinology. 7, 2, p. 115-127 13 p.

Research output: Contribution to journalArticle

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37 Citations (Scopus)
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Change in FEV1 and FeNO measurements as predictors of future asthma outcomes in children

Fielding, S., Pijnenburg, M., de Jongste, J. C., Pike, K. C., Roberts, G., Petsky, H., Chang, A. B., Fritsch, M., Frischer, T., Szefler, S., Gergen, P., Vermeulen, F., Vael, R. & Turner, S., Feb 2019, In : Chest. 155, 2, p. 331-341 11 p.

Research output: Contribution to journalArticle

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10 Citations (Scopus)
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Child health in Scotland: Getting it right for every child?

Turner, S. & Ahmed, S., 23 Dec 2019, In : BMJ Paediatrics Open. 3, 1, 4 p., e000420.

Research output: Contribution to journalEditorial

Open Access
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Clinical utility of fractional exhaled nitric oxide in the management of asthma and COPD

Turner, S. W., Chang, A. B. & Yang, I. A., 1 Dec 2019, In : Breathe. 15, 4, p. 306-316 11 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
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