Research Output

2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In : ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

Research output: Contribution to journalArticle

1H spin-lattice NMR relaxation in the presence of residual dipolar interactions: Dipolar relaxation enhancement

Kruk, D., Rochowski, P., Florek-Wojciechowska, M., Sebastião, P. J., Lurie, D. J. & Broche, L. M., Sep 2020, In : Journal of Magnetic Resonance. 318, 7 p., 106783.

Research output: Contribution to journalArticle

4,4,16-Trifluoropalmitate: design, synthesis, tritiation, radiofluorination and pre-clinical PET imaging studies on myocardial fatty acid oxidation

Colombano, A., Dall'angelo, S., Kingston, L., Grönberg, G., Correia, C., Passannante, R., Baz, Z., Morcillo, M. A., Elmore, C., Llop, J. & Zanda, M., 27 Aug 2020, In : ChemMedChem.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, 10 p., dmm042655.

Research output: Contribution to journalArticle

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A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization

Kiel, C., Berber, P., Karlstetter, M., Aslanidis, A., Strunz, T., Langmann, T., Grassmann, F. & Weber, B. H. F., Apr 2020, In : International Journal of Molecular Sciences. 21, 8, 2689.

Research output: Contribution to journalArticle

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2 Citations (Scopus)
1 Downloads (Pure)

Addition of Broad Bean Hull to Wheat Flour for the Development of High-Fiber Bread: Effects on Physical and Nutritional Properties

Ni, Q., Ranawana, V., Hayes, H., Hayward, N., Stead, D. & Raikos, V., 25 Sep 2020, In : Foods. 9, 9, 15 p., 1192.

Research output: Contribution to journalArticle

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Adolescent cannabis exposure increases heroin reinforcement in rats genetically vulnerable to addiction

Scifo, A., Lecca, D., Pisanu, A., Valentini, V., Piras, G., Sil, A., Cadoni, C. & Di Chiara, G., Apr 2020, In : Neuropharmacology. 166, 107974.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A dot-stripe Turing model of joint patterning in the tetrapod limb

Scoones, J. C. & Hiscock, T. W., 12 Apr 2020, In : Development. 147, 8, 12 p., dev183699.

Research output: Contribution to journalArticle

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Agrin induces long term osteochondral regeneration by supporting repair morphogenesis

Eldridge, S., Barawi, A., Wang, H., Roelofs, A., Kaneva, M., Guan, Z., Lydon, H., Thomas, B. L., Thorup, A-S., Fernandez Fernandez, B., Caxaria, S., Strachan, D., Ali, A., Shanmuganathan, K., Pitzalis, C., Whiteford, J., Henson, F., McCaskie, A., de Bari, C. & Dell'Accio, F., 2 Sep 2020, In : Science translational medicine. 12, 559, eaax9086.

Research output: Contribution to journalArticle

A mega-analysis of expression quantitative trait loci in retinal tissue

Strunz, T., Kiel, C., Grassmann, F., Ratnapriya, R., Kwicklis, M., Karlstetter, M., Fauser, S., Arend, N., Swaroop, A., Langmann, T., Wolf, A. & Weber, B. H. F., 1 Sep 2020, In : PLoS Genetics. 16, 9, p. e1008934 18 p., e1008934.

Research output: Contribution to journalArticle

Open Access

Anaemia and incidence of post stroke dementia

Myint, P. K., Macleod, M. J., Clark, A. B., Smith, T. O., Bettencourt-Silva, J. H., Metcalf, A. K. & Potter, J. F., Apr 2020, In : Clinical Neurology and Neurosurgery. 191, 105688.

Research output: Contribution to journalArticle

Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

Research output: Contribution to journalArticle

A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

Westbury, S. K., Whyte, C. S., Stephens, J., Downes, K., Turro, E., Claesen, K., Mertens, J. C., Hendriks, D., Latif, AL., Leishman, E. J., NIHR BioResource, Mutch, N. J., Campbell Tait, R. & Mumford, A. D., Sep 2020, In : Journal of Thrombosis and Haemostasis. 18, 9, p. 2209-2214 6 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

A new Publisher for Toxicology Research

Wallace, H., Feb 2020, In : Toxicology Research. 9, 1, p. 1 1 p.

Research output: Contribution to journalEditorial

A novel 4-dimensional live-cell imaging system to study leukocyte-endothelial dynamics in ANCA-associated vasculitis

Walls, C. A., Basu, N., Hutcheon, G., Erwig, L. P., Little, M. A. & Kidder, D., Apr 2020, In : Autoimmunity. 53, 3, p. 148-155 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A Novel Allosteric Modulator of the Cannabinoid CB1 Receptor Ameliorates Hyperdopaminergia Endophenotypes in Rodent Models

Mielnik, C. A., Sugamori, K. S., Finlay, D. B., Thorpe, H. H. A., Schapira, M., Sivananthan, N., Li, C. K., lam, V. M., Harrington, S., Abdelrahman, M. H., Trembleau, L. A., Burnham, W. M., Khokhar, J. Y., Salahpour, A., Ramsey, A. J., Glass, M., Greig, I. & Ross, R. A., 10 Aug 2020, (Accepted/In press) In : Neuropsychopharmacology.

Research output: Contribution to journalArticle

An overview of prevalence, determinants and health outcomes of polypharmacy

Khezrian, M., McNeil, C. J., Murray, A. D. & Myint, P. K., 12 Jun 2020, In : Therapeutic Advances in Drug Safety. 11, p. 1-10 10 p.

Research output: Contribution to journalArticle

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Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

Leach, A., Smyth, P., Ferguson, L., Steven, J., Greene, M. K., Branco, C. M., McCann, A. P., Porter, A., Barelle, C. J. & Scott, C. J., 21 Jul 2020, In : Nanoscale. 12, 27, p. 14751-14763 13 p.

Research output: Contribution to journalArticle

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An Update on Cardiac Magnetic Resonance Imaging in Takotsubo Cardiomyopathy

Gunasekara, M. Y., Mezincescu, A. M. & Dawson, D. K., May 2020, In : Current Cardiovascular Imaging Reports. 13, 5, 17.

Research output: Contribution to journalReview article

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1 Citation (Scopus)
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A portrait of the immune response to proliferative kidney disease (PKD) in rainbow trout

Bailey, C., Holland, J. W., Secombes, C. J. & Tafalla, C., 31 May 2020, In : Parasite Immunology. 42, 8, 13 p., e12730.

Research output: Contribution to journalReview article

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A sensorimotor control framework for understanding emotional communication and regulation.

Williams, J. H. G., Huggins, C. F., Zupan, B., Willis, M., Van Rheenen, T. E., Sato, W., Palermo, R., Ortner, C., Krippl, M., Kret, M., Dickson, J. M., Li, C-S. R. & Lowe, L., May 2020, In : Neuroscience & Biobehavioral Reviews. 112, p. 503-518 16 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
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Association between breast cancer risk and disease aggressiveness: Characterizing underlying gene expression patterns

Ugalde-Morales, E., Grassmann, F., Humphreys, K., Li, J., Eriksson, M., Tobin, N. P., Borg, Å., Vallon-Christersson, J., Hall, P. & Czene, K., 5 Sep 2020, In : International Journal of Cancer. 11 p.

Research output: Contribution to journalArticle

Open Access

Association of Inflammation With Pronociceptive Brain Connections in Rheumatoid Arthritis Patients With Concomitant Fibromyalgia

Kaplan, C. M., Schrepf, A., Ichesco, E., Larkin, T., Harte, S. E., Harris, R. E., Murray, A. D., Waiter, G. D., Clauw, D. J. & Basu, N., Jan 2020, In : Arthritis & Rheumatology. 72, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Associations between prenatal indicators of mechanical loading and proximal femur shape: findings from a population-based study in ALSPAC offspring

Frysz, M., Tobias, J. H., Lawlor, D. A., Aspden, R. M., Gregory, J. S. & Ireland, A., 1 Sep 2020, In : Journal of musculoskeletal & neuronal interactions. 20, 3, p. 301-313 13 p.

Research output: Contribution to journalArticle

Open Access

A systematic review of guidelines for internal validity in the design, conduct and analysis of biomedical experiments involving laboratory animals

Vollert, J., Schenker, E., Macleod, M., Bespalov, A., Wuerbel, H., Michel, M. C., Dirnagl, U., Potschka, H., Waldron, A-M., Wever, K. E., Steckler, T., Casteele, T. V. D., Altevogt, B., Sil, A. & SC Rice, A., Apr 2020, In : BMJ Open Science. 4, 1, 8 p., e100046.

Research output: Contribution to journalLiterature review

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A systematic review of how emotional self-awareness is defined and measured when comparing autistic and non-autistic groups

Huggins, C. F., Donnan, G., Cameron, I. M. & Williams, J. H. G., Sep 2020, In : Research in Autism Spectrum Disorders. 77, 18 p., 101612.

Research output: Contribution to journalReview article

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A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

International AMD Genomics Consortium (IAMDGC), 31 Jan 2020, In : Scientific Reports. 10, 16 p., 1584.

Research output: Contribution to journalArticle

Open Access
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A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In : Microorganisms. 8, 7, 14 p., 1066.

Research output: Contribution to journalArticle

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Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression

Rupprechter, S., Romaniuk, L., Series, P., Hirose, T., Hawkins, E., Sandu-Giuraniuc, A-L., Waiter, G. D., McNeil, C. J., Shen, X., Harris, M. A., Campbell, A., Porteous, D., Macfarlane, J. A., Lawrie, S. M., Murray, A. D., Delgado, M. R., McIntosh, A. M., Whalley, H. C. & Steele, J. D., Jun 2020, In : Brain. 143, 6, p. 1946-1956 11 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
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BPA and risk assessment

Palmer, K. & Speirs, V., Apr 2020, In : The Lancet Diabetes and Endocrinology. 8, 4, p. 269 1 p.

Research output: Contribution to journalLetter

Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

Varsou, O., Macleod, M. J., Schwarzbauer, C., Murray, A. D., Dinis Fernandes, C., Stringer, M. S. & Turnbull, K., Jun 2020, In : Neurological Sciences. 41, 6, p. 1633-1635 3 p.

Research output: Contribution to journalArticle

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Brain region–specific lipid alterations in the PLB4 hBACE1 knock-in mouse model of Alzheimer’s disease

Dey, M., Gunn-Moore, F. J., Platt, B. & Smith, T. K., 31 Aug 2020, In : Lipids in Health & Disease. 19, 201.

Research output: Contribution to journalArticle

Open Access
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Brainstem volume mediates seasonal variation in depressive symptoms: A cross sectional study in the UK Biobank cohort

Majrashi, N. A., Ahearn, T. S. & Waiter, G. D., 27 Feb 2020, In : Scientific Reports. 10, 12 p., 3592.

Research output: Contribution to journalArticle

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Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., Apr 2020, In : Archives of Toxicology. 94, p. 1241-1250 10 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
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Candida auris: The path of yeast resistance

Lorenz, A., Apr 2020, In : Research Outreach. 113, p. 138-141 4 p.

Research output: Contribution to journalComment/debate

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Can soluble urokinase plasminogen receptor predict outcomes after cardiac surgery?

Schultz-Swarthfigure, C. T., McCall, P., Docking, R., Galley, H. & Shelley, B., 25 Sep 2020, (Accepted/In press) In : Interactive Cardiovascular and Thoracic Surgery.

Research output: Contribution to journalArticle

Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs. Novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart

Tocchetti, C. G., Ameri, P., de Boer, R. A., D'Alessandra, Y., Russo, M., Sorriento, D., Ciccarelli, M., Kiss, B., Bertrand, L., Dawson, D., Falcao-Pires, I., Giacca, M., Hamdani, N., Linke, W. A., Mayr, M., van der Velden, J., Zacchigna, S., Ghigo, A., Hirsch, E., Lyon, A. R. & 5 others, Görbe, A., Ferdinandy, P., Madonna, R., Heymans, S. & Thum, T., 1 Sep 2020, In : Cardiovascular Research. 116, 11, p. 1820-1834 14 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
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Catalase T-deficient fission yeast meiocytes show resistance to ionizing radiation

Muhtadi, R., Lorenz, A., Mpaulo, S., Siebenwirth, C. & Scherthan, H., 17 Sep 2020, In : Antioxidants. 9, 9, 17 p., 881.

Research output: Contribution to journalArticle

Open Access

CFTR modulators dampen Aspergillus-induced reactive oxygen species production by cystic fibrosis phagocytes

Currie, A. J., Main, E. T., Wilson, H. M., Armstrong-James, D. & Warris, A., 24 Jul 2020, In : Frontiers in cellular and infection microbiology. 10, p. 372 11 p., 372.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 2020, In : Brain Communications. 2, 1, 17 p., fcaa033.

Research output: Contribution to journalArticle

Open Access
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Circulating asymmetric dimethylarginine and cognitive decline: A 4‐year follow‐up study of the 1936 Aberdeen Birth Cohort

Malden, D. E., Mangoni, A. A., Woodman, R. J., Thies, F., McNeil, C., Murray, A. D. & Soiza, R. L., 8 Jun 2020, In : International Journal of Geriatric Psychiatry. 35, 10, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

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Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial

Liao, D. S., Grossi, F. V., El Mehdi, D., Gerber, M. R., Brown, D. M., Heier, J. S., Wykoff, C. C., Singerman, L. J., Abraham, P., Grassmann, F., Nuernberg, P., Weber, B. H. F., Deschatelets, P., Kim, R. Y., Chung, C. Y., Ribeiro, R. M., Hamdani, M., Rosenfeld, P. J., Boyer, D. S., Slakter, J. S. & 1 others, Francois, C. G., Feb 2020, In : Ophthalmology. 127, 2, p. 186-195 10 p.

Research output: Contribution to journalArticle

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7 Citations (Scopus)
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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
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COVID-19: No benefit of chest inclusion in acute abdomen CT

Brennan, C., Morrissey, B., Dubois-Marshall, S., McAteer, D., Qadir, A. & Ramsay, G., 13 Aug 2020, In : British Journal of Surgery.

Research output: Contribution to journalLetter

Open Access

COVID-19 and Anatomy: Stimulus and Initial Response

Brassett, C., Cosker, T., Davies, D. C., Dockery, P., Gillingwater, T. H., Lee, T. C., Milz, S., Parson, S. H., Quondamatteo, F. & Wilkinson, T., 1 Sep 2020, In : Journal of Anatomy. 237, 3, p. 393-403 11 p.

Research output: Contribution to journalReview article

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
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