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2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In : ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

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1H spin-lattice NMR relaxation in the presence of residual dipolar interactions: Dipolar Relaxation

Kruk, D., Rochowski, P., Florek-Wojciechowska, M., Sebastiao, P., Lurie, D. & Broche, L., 5 Jul 2020, (Accepted/In press) In : Journal of Magnetic Resonance.

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Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, 10 p., dmm042655.

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A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

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Anaemia and incidence of post stroke dementia

Myint, P. K., Macleod, M. J., Clark, A. B., Smith, T. O., Bettencourt-Silva, J. H., Metcalf, A. K. & Potter, J. F., Apr 2020, In : Clinical Neurology and Neurosurgery. 191, 105688.

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Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

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A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

Westbury, S. K., Whyte, C. S., Stephens, J., Downes, K., Turro, E., Claesen, K., Mertens, J. C., Hendriks, D., Latif, AL., Leishman, E. J., NIHR BioResource, Mutch, N. J., Campbell Tait, R. & Mumford, A. D., 23 Jul 2020, In : Journal of Thrombosis and Haemostasis. 6 p.

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An overview of prevalence, determinants and health outcomes of polypharmacy

Khezrian, M., McNeil, C. J., Murray, A. D. & Myint, P. K., 12 Jun 2020, In : Therapeutic Advances in Drug Safety. 11, p. 1-10 10 p.

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Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

Leach, A., Smyth, P., Ferguson, L., Steven, J., Greene, M. K., Branco, C. M., McCann, A. P., Porter, A., Barelle, C. J. & Scott, C. J., 21 Jul 2020, In : Nanoscale. 12, 27, p. 14751-14763 13 p.

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A sensorimotor control framework for understanding emotional communication and regulation.

Williams, J. H. G., Huggins, C. F., Zupan, B., Willis, M., Van Rheenen, T. E., Sato, W., Palermo, R., Ortner, C., Krippl, M., Kret, M., Dickson, J. M., Li, C-S. R. & Lowe, L., 2020, In : Neuroscience & Biobehavioral Reviews. 112, p. 503-518 16 p.

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Association of Inflammation With Pronociceptive Brain Connections in Rheumatoid Arthritis Patients With Concomitant Fibromyalgia

Kaplan, C. M., Schrepf, A., Ichesco, E., Larkin, T., Harte, S. E., Harris, R. E., Murray, A. D., Waiter, G. D., Clauw, D. J. & Basu, N., Jan 2020, In : Arthritis & Rheumatology. 72, 1, p. 41-46 6 p.

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A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In : Microorganisms. 8, 7, 14 p., 1066.

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Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression

Rupprechter, S., Romaniuk, L., Series, P., Hirose, T., Hawkins, E., Sandu-Giuraniuc, A-L., Waiter, G. D., McNeil, C. J., Shen, X., Harris, M. A., Campbell, A., Porteous, D., Macfarlane, J. A., Lawrie, S. M., Murray, A. D., Delgado, M. R., McIntosh, A. M., Whalley, H. C. & Steele, J. D., Jun 2020, In : Brain. 143, 6, p. 1946-1956 11 p.

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Brain hyperintensities in magnetic resonance imaging of patients with mild acute focal neurology

Varsou, O., Macleod, M. J., Schwarzbauer, C., Murray, A. D., Dinis Fernandes, C., Stringer, M. S. & Turnbull, K., Jun 2020, In : Neurological Sciences. 41, 6, p. 1633-1635 3 p.

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Brainstem volume mediates seasonal variation in depressive symptoms: A cross sectional study in the UK Biobank cohort

Majrashi, N. A., Ahearn, T. S. & Waiter, G. D., 27 Feb 2020, In : Scientific Reports. 10, 3592.

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Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., Apr 2020, In : Archives of Toxicology. 94, p. 1241-1250 10 p.

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Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 2020, In : Brain Communications. 2, 1, 17 p., fcaa033.

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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Current concepts in tumour-derived organoids

Porter, R. J., Murray, G. & McLean, M. H., 30 Jul 2020, In : British Journal of Cancer.

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Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

Moore, H., Gando, S., Iba, T., Kim, P. Y., Yeh, C. H., Brohi, K., Hunt, B. J., Levy, J. H., Draxler, D. F., Stanworth, S. J., Görlinger, K., Neal, M. D., Schreiber, M. A., Barrett, C. D., Medcalf, R. L., Moore, E. E., Mutch, N. J., Thachil, J., Urano, T., Thomas, S. & 2 others, Scărlătescu, E. & Walsh, M., Mar 2020, In : Journal of Thrombosis and Haemostasis. 18, 3, p. 740-747 8 p.

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Delirium screening in the intensive care unit using emerging QEEG techniques: A pilot study

Hunter, A., Crouch, B., Webster, N. & Platt, B., 13 Jan 2020, In : AIMS Neuroscience. 7, 1, p. 1-16 16 p.

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Dense active matter model of motion patterns in confluent cell monolayers

Henkes, S., Kostanjevec, K., Collinson, J. M., Sknepnek, R. & Bertin, E., 16 Mar 2020, In : Nature Communications. 11, 9 p., 1405.

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Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 30 Jul 2020, In : Bioconjugate Chemistry.

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Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 9 Jul 2020, In : ChemMedChem. 13 p.

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Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

Mayer, C-D., de La Giclais, S. M., Alsehly, F. & Hoppler, S., May 2020, In : Genes. 11, 5, 23 p., 538.

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Dynamics of the transcriptional landscape during human fetal testis and ovary development

Lecluze, E., Rolland, A. D., Filis, P., Evrard, B., Leverrier-Penna, S., Ben Maamar, M., Coiffec, I., Lavoué, V., Fowler, P. A., Mazaud Guittot, S., Jégou, B. & Chalmel, F., May 2020, In : Human Reproduction. 35, 5, p. 1099-1119 21 p.

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Epitope shaving promotes fungal immune evasion

Childers, D., Mol Avelar, G., Bain, J., Pradhan, A., Larcombe, D. E., Netea, M. G., Erwig, L. P., Gow, N. A. R. & Brown, A. J. P., Jul 2020, In : mBio. 11, 4, 13 p., e00984-20.

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Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

Kleeman, S. O., Koelzer, V. H., Jones, H. J. S., Vazquez, E. G., Davis, H., East, J. E., Arnold, R., Koppens, M. A. J., Blake, A., Domingo, E., Cunningham, C., Beggs, A. D., Pestinger, V., Loughrey, M. B., Wang, L-M., Lannagan, T. R. M., Woods, S. L., Worthley, D., The S:CORT Consortium, Tomlinson, I. & 3 others, Dunne, P. D., Maughan, T. & Leedham, S. J., 2020, In : Gut. 69, p. 1092-1103 12 p.

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Expression of the Insulin-like Growth Factor system in first and second trimester human embryonic and fetal gonads

Mamsen, L. S., Zafeiri, A., Bøtkjær, J. A., Rasmussen, J. H., Ernst, E., Oxvig, C., Fowler, P. A. & Andersen, C. Y., 29 Jul 2020, In : Journal of Clinical Endocrinology and Metabolism.

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Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery

Kaira, B., Slater, A., McCrae, K., Dreveny, I., Ummay, S., Mutch, N., Searle, M. & Emsley, J., 19 Jun 2020, In : Blood.

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Foxh1/Nodal defines context-specific direct maternal Wnt/β-catenin target gene regulation in early development

Afouda, B., Nakamura, Y., Shaw, S., Charney, R. M., Paraiso, K. D., Blitz, I. L., Cho, K. W. Y. & Hoppler, S., 24 Jul 2020, In : iScience. 23, 7, 34 p., 101314.

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Geometric description for the anatomy of the mitral valve: A review

Oliveira, D., Srinivasan, J., Espino, D., Buchan, K., Dawson, D. & Shepherd, D., 3 Apr 2020, In : Journal of Anatomy. 237, 2, p. 209-224 16 p.

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1 Citation (Scopus)

Host and pathogen autophagy are central to the inducible local defences and systemic response of the giant kelp Macrocystis pyrifera against the oomycete pathogen Anisolpidium ectocarpii

Murua, P., Müller, D. G., Etemadi, M., van West, P. & Gachon, C. M. M., Jun 2020, In : New Phytologist. 226, 5, p. 1445-1460 16 p.

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Host immune response against the emerging fungal pathogen Candida auris: transcriptional and functional insights

Bruno, M., Kersten, S., Bain, J. M., Jaeger, M., Rosati, D., Kruppa, M. D., Lowman, D. W., Rice, P. J., Graves, B., Zuchao, M., Ning Jiao, Y., Chowdhary, A., Renieris, G., van de Veerdonk, F. L., Kullberg, B-J., Giamarellos-Bourboulis, E. J., Hoischen, A., Gow, N. A. R., Brown, A. J. P., Meis, J. F. & 2 others, Williams, D. L. & Netea, M. G., 27 Jul 2020, (Accepted/In press) In : Nature Microbiology.

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Hypoxia PET/CT and Colorectal Cancer: A Case Report

Laws, K., Zanda, M., Dall'angelo, S., McKiddie, F., Kerr, K., Murray, G. I., Fleming, I. & Samuel, L., 29 Jul 2020, (Accepted/In press) In : Journal of Case Reports and Images in Oncology.

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Identifying Candida albicans Gene Networks Involved in Pathogenicity

Thomas, G., Bain, J. M., Budge, S., Brown, A. J. P. & Ames, R. M., Apr 2020, In : Frontiers in Genetics. 11, 12 p., 375.

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Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

Sirinukunwattana, K., Domingo, E., Richman, S., Redmond, K. L., Blake, A., Verrill, C., Leedham, S. J., Chatzipli, A., Hardy, C., Whalley, C., Wu, C-H., Beggs, A. D., McDermott, U., Dunne, P. D., Meade, A. A., Walker, S. M., Murray, G., Samuel, L. M., Seymour, M., Tomlinson, I. & 4 others, Quirke, P., Maughan, T., Rittscher, J. & Koelzer, V. H., 20 Jul 2020, In : Gut.

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Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia

Craig, S. G., Humphries, M. P., Alderdice, M., Bingham, V., Richman, S. D., Loughrey, M. B., Coleman, H. G., Viratham-Pulsawatdi, A., McCombe, K., Murray, G. I., Blake, A., Domingo, E., Robineau, J., Brown, L., Fisher, D., Seymour, M. T., Quirke, P., Bankhead, P., McQuaid, S., Lawler, M. & 4 others, McArt, D. G., Maughan, T. S., James, J. A. & Salto-Tellez, M., 20 Jul 2020, In : British Journal of Cancer.

Research output: Contribution to journalArticle