Research Output 1979 2019

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Patent
2019

Synthetic Retinoids for Use in RAR Mediated Conditions

Whiting, A., Chisholm, D., Valentine, R., Greig, I. R., McCaffery, P. J. A. & Alkhatib, T., 18 Apr 2019, IPC No. C07C 63/66, A61K 31/192, A61K 31/203, A61P 25/28, C07D 209/82, C07D 215/06, European Patent Office, Patent No. WO2017174999, Priority date 6 Apr 2017, Priority No. 2017050977

Research output: Patent

Retinoids
2017

Synthetic retinoids for use in RAR mediated conditions

Greig, I. R., McCaffery, P. J. A., Whiting, A., Valentine, R., Chisholm, D. & Khatib, T., 12 Oct 2017, Patent No. WO2017174999

Research output: Patent

Retinoids
2015

Phenothiazine compounds for treating mild cognitive impairment

Wischik, C. M., Harbaran, D. V., Riedel, G., Deiana, S., Goatman, E. A., Wischik, D. J., Murray, A. D. & Staff, R. T., 15 Dec 2015, Patent No. US9211294, 17 Jun 2008, Priority date 19 Jun 2007, Priority No. 60/945006

Research output: Patent

Cognitive Dysfunction
phenothiazine
2014
1 Downloads (Pure)

Fish Vaccine

Wawra, S., Van West, P. & Secombes, C. J., 4 Dec 2014, IPC No. A61K38/16; C07K14/37; C12N15/62, Patent No. WO2014191759, Priority date 30 May 2013, Priority No. GB20130009664 20130530

Research output: Patent

vaccines
fish
nucleic acids
eukaryotic cells
plasma membrane

Fluoro-perhexiline compounds and their therapeutic use

Greig, I. R., Tseng, C-C. & Zanda, M., 30 Oct 2014, Patent No. WO2014184561

Research output: Patent

2013

18f-labelled barbiturate compounds for use as positron emission imaging agents

Greig, I. R., Zanda, M., Platt, B. & Calamai, E., 21 Mar 2013, Patent No. WO2013038153

Research output: Patent

Aryl-Phenyl-Sulfonamido-Cycloalkyl Compounds and Their Use

Greig, I. R., Sheridan, R. M., Fisher, R., Tozer, M. J., Clase, J. A., Smith, A., Tufnell, A. R. & van 't Hof, R. J., 19 Sep 2013, Patent No. US2013245018

Research output: Patent

Bone and Bones
Rheumatoid Arthritis
Anistreplase
Bone Neoplasms
Psoriatic Arthritis
2011
6 Downloads (Pure)
File
Salt
Drugs
Alzheimer's Disease
Invention

N-(ARYLALKYL)-1H-INDOLE-2-SULFONIC ACID AMIDE COMPOUNDS AND THEIR THERAPEUTIC USE AS CANNABINOID ALLOSTERIC MODULATORS

Greig, I. R., Ross, R. A., Trembleau, L. A. C., Pertwee, R. G. & Abdelrahman, M. H., 28 Feb 2011, IPC No. WO2012117216, Patent No. WO2012117216

Research output: Patent

Cannabinoid Receptors
Sulfonic Acids
Cannabinoids
Therapeutic Uses
Amides
2010

1,5-Diaryl-pyrazoles and their use as cannabinoid receptor neutral antagonists

Greig, I. R. & Ross, R. A., 25 Feb 2010, IPC No. WO2010020762, Patent No. WO2010020762

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cannabinoid Receptors
Breast Neoplasms
Smoking
Patents and inventions
Salts
Pharmaceutical Preparations
xanthylium
27 Downloads (Pure)

Antibodies specifically directed to a soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N., 2 Sep 2010, Patent No. US8697845 B2, Priority date 15 Apr 2014

Research output: Patent

Open Access
File
HLA-D Antigens
Antibodies
19 Downloads (Pure)

Antigen Binding Domains from Fish

Dooley, H., Porter, A. J. R. & Flajnik, M. F., 3 Mar 2010, IPC No. C07K 16/00; 16/18; 15/63, Patent No. 1419179, Priority date 10 Aug 2001, Priority No. GB0119553; GB0210508

Research output: Patent

Open Access
File
Fish
Antigens
Immunoglobulin Isotypes
DNA sequences

Aryl-phenyl-sulfonamide-cycloalkyl compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J. & Tufnell, A. R., 25 Mar 2010, IPC No. WO2010/032009 , Patent No. WO2010/032009

Research output: Patent

2 Downloads (Pure)

Aryl-phenyl-sulfonamide-phenylene compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J., Tufnell, A. R. & van 't Hof, R. J., 25 Mar 2010, IPC No. WO2010/032010, Patent No. WO2010/032010

Research output: Patent

File
Sulfonamides
Bone and Bones
Rheumatoid Arthritis
Bone Neoplasms
Psoriatic Arthritis
7 Downloads (Pure)
File
tau Proteins
Hydrates
Labels
Salts
Ligands

Materials and methods for medical imaging

Smith, T. A. D., Trembleau, L. A. C., McLaughlin, A. & Simpson, M., 2010, IPC No. WO2009056837, Patent No. GB2467494 (A)

Research output: Patent

positrons
inventions
marking
emitters
platforms
2009

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Idris, A. I. & Van't Hof, R. J., 2009, Patent No. US7598289

Research output: Patent

Neuroprotective 3-phenylacrylonitrile (3-PAN) derivatives

Greig, I. R., Teismann, P., Hanisch, U-K. & Bruck, W., 16 Sep 2009, IPC No. GB2458259, Patent No. GB2458259

Research output: Patent

Derivatives
Hydrogen
Neurodegenerative diseases
Chemical analysis
Pharmaceutical Preparations
2 Downloads (Pure)

Therapeutic Use of Diaminophenothiazines: WO2009044127

Wischik, C. M., Damon J., W., Storey, J. M. D. & Harrington, C. R., 9 Apr 2009, IPC No. WO2009/044127

Research output: Patent

File
Dosage Forms
Therapeutic Uses
Pharmacokinetics

Treatment and Diagnosis of Behavioural Disorders

Miedzybrodzka, Z. H., St Clair, D. M., Muller, B. M., Neves-Pereira, M. D. L. & Massie, D., 2009, IPC No. C12Q 1/68 (2006.01), Patent No. WO/2009/144480

Research output: Patent

Pharmaceutical Preparations

US20120107320 - Antibodies specifically directed to the soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N., 28 Feb 2009, IPC No. US20120107320

Research output: Patent

HLA-D Antigens
Antibodies
2008

[11C]Methoxy-radiolabelled 2,3',4,5' - Tetramethoxystilbene (TMS) and its preparation and use8

Schweiger, L. & Smith, T. A. D., 2008, Patent No. WO2009001046

Research output: Patent

1,5-diaryl-pyrazoles as cannabinoid receptor neutral antagonists useful as therapeutic agents

Greig, I. R., Ross, R. A. & Pertwee, R. G., 21 Aug 2008, IPC No. A61K31/415; A61P29/00; C07D231/12; , Patent No. WO2008/099139

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cognition
Smoking
Osteitis Deformans

2',4'-Dichloro-biphenyl-4-yl-hydroxyketones and related compounds and their use as therapeutic agents

Greig, I. R., Van T Hof, R. J. & Ralston, S., 11 Sep 2008, IPC No. US20080221220, Patent No. US20080221220

Research output: Patent

Biphenyl-4-yl-sulfonic acid arylamines and their use as therapeutic agents

Greig, I. R., van't Hof, R. J. & Ralston, S., 2008, Patent No. WO2008/114022

Research output: Patent

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Van T Hof, R. J. & Mohamed, A. I. I., 18 Dec 2008, IPC No. US7598289, Patent No. US7598289

Research output: Patent

2007

Cancer Therapy Prognosis and Target

Collie-Duguid, E. S. R., Petty, R. D. & Kerr, K. M., 2007, Patent No. BOA:0519405.5; PCT/GB2006/003559 (23/9/05)

Research output: Patent

2 Downloads (Pure)
File
Synucleins
Parkinson Disease
Proteins
2006
2005

Allo and auto-reactive T-cell epitopes from Rhesus protein and their use

Urbaniak, S. & Barker, R. N., 2005, Patent No. EP1135414, application granted 20/03/2005

Research output: Patent

Inhibition of tau-tau-association

Wischik, C. M., Edwards, P. C., Harrington, C. R., Roth, M. & Klug, A., 2005, Patent No. US Patent 6,953,794B2; Granted 11/10/05

Research output: Patent

2004

Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders

Greig, I. R., Mohamed, A. I. I., Ralston, S., Ross, R. A. & Van T Hof, R. J., 2004, Patent No. WO2004/078261

Research output: Patent

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Ralston, S., Greig, I. R., Mohamed, A. I. I. & van't Hof, R. J., 2004, Patent No. WO2004/098582 A2; Publication date 18 November 2004

Research output: Patent

Methods of [ 11C] Radiolabelling Phenothiazine and Phenothiazine-Like Compounds

Schweiger, L. F., Craib, S. A. P., Welch, A. & Sharp, P. F., 27 Sep 2004, IPC No. C07B 59/00 (2006.01), C07D 279/20 (2006.01), Patent No. PCT/GB2004/004153

Research output: Patent

Positron emission tomography
Patents and inventions
Skin
Imaging techniques
Chemical analysis
2003

Alkane diol derivatives as therapeutic agents for the treatment of bone conditions

Ralston, S., Greig, I. R., van't Hof, R. J. & Armour, K. E., 2003, Patent No. WO 03/037321 A1; Publication 8 May 2003

Research output: Patent

Naphthoquinone-type inhibitors of protein aggregation

Wischik, C. M., Horsley, D., Rickard, J. E. & Harrington, C. R., 2003, Patent No. WO 03/007933; published 30.01.03

Research output: Patent

2002

Inhibition of tau-tau-association

Wischik, C. M., Edwards, P. C., Harrington, C. R., Roth, M. & Klug, A., 2002, Patent No. EP0817969; Application Granted 20/06/02

Research output: Patent

3 Downloads (Pure)
File
7 Downloads (Pure)
File

Neurofibrillary labels

Wischik, C. M., Harrington, C. R., Rickard, J. E. & Horsley, D., 2002, Patent No. WO 02/075318 A2; published 26.09.02

Research output: Patent