Life Sciences & Medicine

  • AB25 2ZD

Research Output 1970 2019

2019
2 Citations (Scopus)

25-Hydroxyvitamin D – Should labs be measuring it?

Avenell, A., Bolland, M. J. & Grey, A., 1 Mar 2019, In : Annals of Clinical Biochemistry. 56, 2, p. 188-189 2 p.

Research output: Contribution to journalEditorial

Vitamin D
Osteomalacia
Rickets
Vitamin D Deficiency
Causality
2 Citations (Scopus)

27 years of prenatal diagnosis for Huntington disease in the United Kingdom

Piña-Aguilar, R. E., Simpson, S. A., Alshatti, A., Clarke, A., Craufurd, D., Dorkins, H., Doye, K., Lahiri, N., Lashwood, A., Lynch, C., Miller, C., Morton, S., O’Driscoll, M., Quarrell, O. W., Rae, D., Strong, M., Tomlinson, C., Turnpenny, P., Miedzybrodzka, Z. & UK HD Predictive Testing Consortium, Jul 2019, In : Genetics in Medicine. 21, p. 1639–1643 5 p.

Research output: Contribution to journalArticle

Preimplantation Diagnosis
Huntington Disease
Prenatal Diagnosis
United Kingdom
Neurodegenerative Diseases
1 Citation (Scopus)
8 Downloads (Pure)

AAPT Diagnostic Criteria for Fibromyalgia

Arnold, L. M., Bennett, R. M., Crofford, L. J., Dean, L. E., Clauw, D. J., Goldenberg, D. L., Fitzcharles, M-A., Paiva, E. S., Staud, R., Sarzi-Puttini, P., Buskila, D. & Macfarlane, G. J., Jun 2019, In : Journal of Pain. 20, 6, p. 611-628 18 p.

Research output: Contribution to journalReview article

Open Access
File
Fibromyalgia
Pain
Somatoform Disorders
Clinical Trials
Chronic Pain

ABC Transporter Genes Show Upregulated Expression in Drug Resistant Clinical Isolates of Candida auris: a Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

Wasi, M., Khandelwal, N. K., Moorhouse, A. J., Nair, R., Vishwakarma, P., Ruiz, G. B., Ross, Z. K., Lorenz, A., Rudramurthy, S. M., Chakrabarti, A., Lynn, A. M., Mondal, A. K., Gow, N. A. R. & Prasad, R., Jul 2019, In : Frontiers in Microbiology. 10, 16 p., 1445.

Research output: Contribution to journalArticle

Open Access
File
ATP-Binding Cassette Transporters
Candida
Genome
Pharmaceutical Preparations
Genes

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., 10 Apr 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Open Access
Retinoic Acid Receptors
AMPA Receptors
Glutamate Receptors
Tretinoin
Ligands
5 Downloads (Pure)

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 1 Jun 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

Research output: Contribution to journalArticle

Open Access
File
Luminescent Proteins
Optical Imaging
Fungi
Fungal Proteins
Mycoses

A case-note review of continued pregnancies found to be at a high risk of Huntington’s disease: considerations for clinical practice

Wadrup, F., Holden, S., MacLeod, R., Miedzybrodzka, Z., Németh, A. H., Owens, S., Pasalodos, S., Quarrell, O., Clarke, A. J. & on behalf of the UK Huntington’s Disease Predictive Testing Consortium, 19 Mar 2019, In : European Journal of Human Genetics. 27, p. 1215-1224 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Prenatal Diagnosis
Pregnancy
High-Risk Pregnancy
Prenatal Care
2 Citations (Scopus)

Accumulation of nitrate and dissolved organic nitrogen at depth in a red soil Critical Zone

Wu, H., Song, X., Zhao, X., Peng, X., Zhou, H., Hallett, P. D., Hodson, M. E. & Zhang, G. L., 1 Mar 2019, In : Geoderma. 337, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

dissolved organic nitrogen
red soil
regolith
nitrates
nitrate

Accuracy of gonadosomatic index in maturity classification and estimation of maturity ogive

Flores, A., Wiff, R., Ganias, K. & Marshall, C. T., 28 Feb 2019, In : Fisheries Research. 210, p. 50-62 13 p.

Research output: Contribution to journalArticle

1 Downloads (Pure)
Open Access
File
Aftercare
Melanoma
Self-Examination
Neoplasms
Skin

A comparison of professional and private time preferences of General Practitioners

Irvine, A., Van der Pol, M. & Phimister, E., 1 Feb 2019, In : Social Science & Medicine. 222, p. 256-264 9 p.

Research output: Contribution to journalArticle

general practitioner
General Practitioners
Patient Preference
Health
Likelihood Functions

A conceptual framework for patient-directed knowledge tools to support patient-centred care: Results from an evidence-informed consensus meeting

Dreesens, D., Stiggelbout, A., Agoritsas, T., Elwyn, G., Flottorp, S., Grimshaw, J., Kremer, L., Santesso, N., Stacey, D., Treweek, S., Armstrong, M., Gagliardi, A., Hill, S., Légaré, F., Ryan, R., Vandvik, P. & van der Weijden, T., 4 May 2019, In : Patient Education and Counseling.

Research output: Contribution to journalArticle

Patient-Centered Care
Consensus
Self Care
Decision Making

Acoustic characterization of sensors used for marine environmental monitoring

Cotter, E., Murphy, P., Bassett, C., Williamson, B. & Polagye, B., 1 Jul 2019, In : Marine Pollution Bulletin. 144, p. 205-215 11 p.

Research output: Contribution to journalArticle

Mammals
environmental monitoring
marine mammal
marine mammals
acoustics

A critical review of the impacts of cover crops on nitrogen leaching, net greenhouse gas balance and crop productivity

Abdalla, M., Hastings, A., Cheng, K., Yue, Q., Chadwick, D., Espenberg, M., Truu, J., Rees, R. M. & Smith, P., 13 May 2019, In : Global Change Biology. 25, 8, p. 2530-2543 14 p.

Research output: Contribution to journalArticle

Open Access
File
cover crop
Greenhouse gases
Leaching
Crops
greenhouse gas
1 Citation (Scopus)

Activity energy expenditure is an independent predictor of energy intake in humans

Hopkins, M., Duarte, C., Beaulieu, K., Finlayson, G., Gibbons, C., Johnstone, A., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 1 Jul 2019, In : International Journal of Obesity. 43, 7, p. 1466–1474 9 p.

Research output: Contribution to journalArticle

Open Access
File
Energy Intake
Energy Metabolism
Basal Metabolism
Body Composition
Diet Records

Actual persuasiveness: Impact of personality, age and gender on message type susceptibility

Ciocarlan, A., Masthoff, J. & Oren, N., 2019, Persuasive Technology: Development of Persuasive and Behavior Change Support Systems - 14th International Conference, PERSUASIVE 2019, Proceedings. Oinas-Kukkonen, H., Win, K. T., Karapanos, E., Karppinen, P. & Kyza, E. (eds.). Cham: Springer-Verlag, p. 283-294 12 p. (Lecture Notes in Computer Science; vol. 11433).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Susceptibility
Persuasive Technology
Persuasion
Reciprocity
Person

A Culture of Control?

Hawick, L., Thomson, A. & Cleland, J., Mar 2019, In : Medical Education. 53, 3, p. 212-214 3 p.

Research output: Contribution to journalComment/debate

student
time

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Glutathione
Zinc
examination
science
employability
physiology
research project

Addressing medication errors in an adult oncology department in Saudi Arabia: A qualitative study

Alharbi, W., Cleland, J. & Morrison, Z., Jul 2019, In : Saudi Pharmaceutical Journal. 27, 5, p. 650-654 5 p.

Research output: Contribution to journalArticle

Open Access
File
Medication Errors
Saudi Arabia
Communication
Delivery of Health Care
Education
Dental Schools
Crowns
Tongue
Tooth
Students

Adiponectin: An indicator for metabolic syndrome

Yosaee, S., Khodadost, M., Esteghamati, A., Speakman, J. R., Djafarian, K., Bitarafan, V. & Shidfar, F., 2 Jun 2019, In : Iranian Journal of Public Health. 48, 6, p. 1106-1115 10 p.

Research output: Contribution to journalArticle

Open Access
File
Adiponectin
Leptin
Healthy Volunteers
Obesity
Fats
4 Downloads (Pure)

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

Ottaviano, G., Chiesa, R., Feuchtinger, T., Vickers, M. A., Dickinson, A., Gennery, A. R., Veys, P. & Todryk, S., 14 Jan 2019, In : Cells. 8, 1, 47.

Research output: Contribution to journalReview article

Open Access
File
Hematopoietic Stem Cell Transplantation
Virus Diseases
Cell- and Tissue-Based Therapy
Viruses
T-Lymphocytes

Advancing human health risk assessment

Lanzoni, A., Castoldi, A. F., Kass, G. E. N., Terron, A., De Seze, G., Bal-Price, A., Bois, F. Y., Delclos, K. B., Doerge, D. R., Fritsche, E., Halldorsson, T., Kolossa-Gehring, M., Hougaard Bennekou, S., Koning, F., Lampen, A., Leist, M., Mantus, E., Rousselle, C., Siegrist, M., Steinberg, P. & 7 othersTritscher, A., Van de Water, B., Vineis, P., Walker, N., Wallace, H., Whelan, M. & Younes, M., Jul 2019, In : EFSA Journal. 17, S1, 21 p., e170712.

Research output: Contribution to journalArticle

Open Access
File
risk assessment
human health
Health
risk assessors
risk managers
1 Citation (Scopus)
7 Downloads (Pure)

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
File
Age of Onset
Walking
Hip
Walkers
Femur Neck

Age-length relationships in UK harbour seals during a period of population decline

Hall, A. J., Mackey, B., Kershaw, J. L. & Thompson, P., 24 Feb 2019, (Accepted/In press) In : Aquatic Conservation: Marine and Freshwater Ecosystems.

Research output: Contribution to journalArticle

Phoca vitulina
population decline
harbor
coast
Scotland
5 Downloads (Pure)

A global, empirical, harmonised dataset of soil organic carbon changes under perennial crops

Ledo, A., Hillier, J., Smith, P., Aguilera, E., Blagodatskiy, S., Brearley, F. Q., Datta, A., Diaz-Pines, E., Don, A., Dondini, M., Dunn, J., Feliciano, D., Lang, R., Liebig, M. A., Llorente, M., Zinn, Y. L., McNamara, N., Ogle, S. M., Qin, Z., Rovira, P. & 5 othersRowe, R., Vicente-Vicente, J. L., Whitaker, J., Yue, Q. & Zerihun, A., 13 May 2019, In : Scientific Data. 6, 57.

Research output: Contribution to journalArticle

Open Access
File
Organic carbon
Crops
Soil
Carbon
bioenergy

A Hexagonal Cell Automaton Model to Imitate Physarum Polycephalum Competitive Behaviour

Awad, A., Pang, W., Lusseau, D. & Coghill, G. M., 30 Apr 2019, (Accepted/In press) Proceedings of the 2019 Conference on Artificial Life.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Downloads (Pure)

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C-D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity
4 Downloads (Pure)

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Muller, B. & Connolly, B., 5 Apr 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression

A literature review of the predictive validity of European dental school selection methods

Cunningham, C., Patterson, F. & Cleland, J., May 2019, In : European Journal of Dental Education. 23, 2, p. 73-87 15 p.

Research output: Contribution to journalArticle

Dental Schools
Aptitude
school
Dentistry
Research
2 Citations (Scopus)

Allometry of fine roots in forest ecosystems

Chen, G., Hobbie, S. E., Reich, P. B., Yang, Y. & Robinson, D., Feb 2019, In : Ecology Letters. 22, 2, p. 322-331 10 p.

Research output: Contribution to journalArticle

allometry
fine root
forest ecosystems
forest ecosystem
biomass

A Lot on Your Plate? Well-to-Well Contamination as an Additional Confounder in Microbiome Sequence Analyses

Walker, A. W., 25 Jun 2019, In : mSystems. 4, 4, 3 p., e00362-19.

Research output: Contribution to journalComment/debate

Open Access
File
Microbiota
Biomass
Sequence Analysis
Decontamination
Artifacts
3 Citations (Scopus)
7 Downloads (Pure)

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler, P., 14 Feb 2019, In : PLoS Biology. 17, 2, e3000002.

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens

AMEE guide no. 123 - How to read studies of educational costs

Maloney, S., Cook, D. A., Golub, R., Foo, J., Cleland, J., Rivers, G., Tolsgaard, M. G., Evans, D., Abdalla, M. E. & Walsh, K., 2019, In : Medical Teacher. 41, 5, p. 497-504 8 p.

Research output: Contribution to journalArticle

decision making
costs
opportunity costs
economics
decision maker
Vocational Education
Pharmacists
Health
Education
Students

A model for spatio-temporal injury surveillance: implications for the evolution of a trauma system

Jansen, J. O., Emerson, P., Morrison, J. J. & Cornulier, T., Feb 2019, In : The journal of trauma and acute care surgery. 86, 2, p. 289-298 10 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Scotland
Hebrides
Health Policy
Islands

Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

Martínez, K. A., Lauritano, C., Druka, D., Romano, G., Grohmann, T., Jaspars, M., Martín, J., Díaz, C., Cautain, B., de la Cruz, M., Ianora, A. & Reyes, F., 27 Jun 2019, In : Marine Drugs. 17, 7, 385.

Research output: Contribution to journalArticle

Open Access
File
Dinoflagellida
Cell Line
Aspergillus fumigatus
Biodiversity
Klebsiella pneumoniae

An advantage for horizontal motion direction discrimination

Pilz, K. S. & Papadaki, D., May 2019, In : Vision Research. 158, p. 164-172 9 p.

Research output: Contribution to journalArticle

Direction compound
Individuality

An Anatomical Evaluation of a conventional Pectoralis II and a Sub-serratus Block for Breast Surgery

Robinson, H., Mishra, S., Davies, L., Craigen, F., Shahana, S. & Parson, S. H., 2019, (Submitted) In : Anesthesia and Analgesia.

Research output: Contribution to journalArticle

1 Citation (Scopus)
5 Downloads (Pure)
Open Access
File
Antigen Receptors
Transgenic Mice
Autoimmune Diseases
Arthritis
Tumor Necrosis Factor-alpha
1 Downloads (Pure)

An Assessment of Students’ and Health Professional’ Abilities to Site Stomas Accurately on Human Cadavers

Arnott, A., Cowpland, L., Jury, J., Keenan, R., McKinley, A. & Scott, D. A., 2019.

Research output: Contribution to conferencePoster

Open Access
File
Cadaver
Ileostomy
Colostomy
Nurses
Students
6 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1172.

Research output: Contribution to journalArticle

Open Access
File
Mycoses
Skin
Infection
Microscopy
Animal Models
1 Downloads (Pure)

An integrated approach to processing WHO-2016 verbal autopsy data: the InterVA-5 model

Byass, P., Hussain-Alkhateeb, L., D'Ambruoso, L., Clark, S., Davies, J., Fottrell, E., Bird, J., Kabudula, C., Tollman, S., Kahn, K., Schiöler, L. & Petzold, M., 30 May 2019, In : BMC medicine . 17, 12 p., 102.

Research output: Contribution to journalArticle

Open Access
File
Autopsy
Mortality
Afghanistan
Cause of Death
Interviews
2 Citations (Scopus)

Annual ring growth of a widespread high arctic shrub reflects past fluctuations in community-level plant biomass

Le Moullec, M., Buchwal, A., Wal, R., Sandal, L. & Hansen, B. B., Jan 2019, In : Journal of Ecology. 107, 1, p. 436-451 16 p.

Research output: Contribution to journalArticle

growth rings
Arctic region
shrub
shrubs
aboveground biomass

A novel external fixation method and its impact on wrist distraction in relation to distal radial fracture

Ashcroft, G. P., Murphy, L., Hanich, A. A., Downing, M., Van Niekerk, A. & Shahana, S., 21 Jun 2019, (Accepted/In press).

Research output: Contribution to conferenceAbstract

Wrist
Ligaments
Metacarpal Bones
Formaldehyde
Tantalum
5 Downloads (Pure)

Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting

Ablett, A. D., Browning, A., Quan, V., Tay, H. S., McCormack, C., Carter, B., Hewitt, J., Myint, P. K. & Older Persons Surgical Outcomes Collaboration (OPSOC), Apr 2019, In : Asian Journal of Surgery. 42, 4, p. 527-534 8 p.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Emergencies
Patients' Rooms
Odds Ratio
Length of Stay