Life Sciences & Medicine

  • AB25 2ZD

Research Output 1970 2020

2019

An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort

Kerr, S. M., Klaric, L., Halachev, M., Hayward, C., Boutin, T. S., Meynert, A. M., Semple, C. A., Tuiskula, A. M., Swan, H., Santoyo-Lopez, J., Vitart, V., Haley, C., Dean, J., Miedzybrodzka, Z., Aitman, T. J. & Wilson, J. F., 29 Jul 2019, In : Scientific Reports. 9, 11 p., 10964.

Research output: Contribution to journalArticle

Open Access
File
Long QT Syndrome
Haplotypes
Sequence Analysis
Research
Population

An advantage for horizontal motion direction discrimination

Pilz, K. S. & Papadaki, D., May 2019, In : Vision Research. 158, p. 164-172 9 p.

Research output: Contribution to journalArticle

Direction compound
Individuality
3 Citations (Scopus)

Anaesthesia care team improves outcomes in surgical patients compared with solo anaesthesiologist: An observational study

Dony, P., Seidel, L., Pirson, M. & Forget, P., Jan 2019, In : European journal of anaesthesiology. 36, 1, p. 64-69 6 p.

Research output: Contribution to journalArticle

Observational Studies
Anesthesia
Length of Stay
Nurses
Mortality

An Anatomical Evaluation of a conventional Pectoralis II and a Sub-serratus Block for Breast Surgery

Robinson, H., Mishra, S., Davies, L., Craigen, F., Shahana, S. & Parson, S. H., 2019, (Submitted) In : Anesthesia and Analgesia.

Research output: Contribution to journalArticle

2 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
Antigen Receptors
Transgenic Mice
Autoimmune Diseases
Arthritis
Tumor Necrosis Factor-alpha

A Narrative Synthesis of Qualitative Studies Conducted to Assess Patient Safety Culture in Hospital Settings

Alqattan, H., Morrison, Z. & Cleland, J. A., 2019, In : Sultan Qaboos University Medical Journal. 19, 2, p. e91-e98 8 p.

Research output: Contribution to journalReview article

Open Access
File
Safety Management
Patient Safety
National Library of Medicine (U.S.)
MEDLINE
Netherlands
2 Downloads (Pure)

An Assessment of Students’ and Health Professional’ Abilities to Site Stomas Accurately on Human Cadavers

Arnott, A., Cowpland, L., Jury, J., Keenan, R., McKinley, A. & Scott, D. A., 2019.

Research output: Contribution to conferencePoster

Open Access
File
Cadaver
Ileostomy
Colostomy
Nurses
Students
6 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity. 43, p. 1795-1802 8 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health

An epigenome-wide association study of sex-specific chronological ageing

McCartney, D. L., Zhang, F., Hillary, R. F., Zhang, Q., Stevenson, A. J., Walker, R. M., Bermingham, M. L., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Evans, K. L., Chandra, T., Deary, I. J., McIntosh, A. M., Yang, J., Visscher, P. M., McRae, A. F. & Marioni, R. E., 15 Nov 2019, (Accepted/In press) In : Genome Medicine.

Research output: Contribution to journalArticle

DNA Methylation
Linear Models
Genome
X-Linked Genes
Quantitative Trait Loci
2 Citations (Scopus)

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1172.

Research output: Contribution to journalArticle

Open Access
File
Mycoses
Skin
Infection
Microscopy
Animal Models
1 Citation (Scopus)
Streptomyces griseus
Lactalbumin
Pronase
lactalbumin
enzymatic treatment

Animal Fibre Production in Europe: Biology, Species, Breeds and Contemporary Utilisation

Galbraith, H., Jul 2019, Advances in Fibre Production Science in South American Camelids and other Fibre Animals . Gerken, M., Renieri, C., Allain, D., Galbraith, H., Gutiérrez, J. P., McKenna, L., Niznikowski, R. & Wurzinger, M. (eds.). Göttingen: Universitätsverlag Göttingen, p. 23- 41 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
animal fibers
dietary fiber
breeds
Biological Sciences
wool

An insight into piscidins: The discovery, modulation and bioactivity of greater amberjack, Seriola dumerili, piscidin

Milne, D. J., Fernández-Montero, Á., Gundappa, M. K., Wang, T., Acosta, F., Torrecillas, S., Montero, D., Zou, J., Sweetman, J. & Secombes, C. J., Oct 2019, In : Molecular Immunology. 114, p. 378-388 11 p.

Research output: Contribution to journalArticle

Head Kidney
Flagellin
Poly I-C
Diet
Spleen
2 Citations (Scopus)
1 Downloads (Pure)

An integrated approach to processing WHO-2016 verbal autopsy data: the InterVA-5 model

Byass, P., Hussain-Alkhateeb, L., D'Ambruoso, L., Clark, S., Davies, J., Fottrell, E., Bird, J., Kabudula, C., Tollman, S., Kahn, K., Schiöler, L. & Petzold, M., 30 May 2019, In : BMC medicine . 17, 12 p., 102.

Research output: Contribution to journalArticle

Open Access
File
Autopsy
Mortality
Afghanistan
Cause of Death
Interviews
1 Citation (Scopus)

An international study of the quality of life of adult patients treated with home parenteral nutrition

Baxter, J. P., Fayers, P. M., Bozzetti, F., Kelly, D., Joly, F., Wanten, G., Jonkers, C., Cuerda, C., Van Gossum, A., Klek, S., Boudreault, M-F., Gilbert, A., Jobin, M., Staun, M., Gillanders, L., Forbes, A., O'Callaghan, M., Martinez Faedo, C., Brunelli, C., Mariani, L. & 1 others, Pironi, L., Aug 2019, In : Clinical Nutrition. 38, 4, p. 1788-1796 9 p.

Research output: Contribution to journalArticle

Open Access
File
Home Parenteral Nutrition
Quality of Life
Linear Models
Psychometrics
Crohn Disease

An investigation into the impact and implications of published papers from retracted research: systematic search of affected literature

Avenell, A., Stewart, F., Grey, A., Gamble, G. & Bolland, M., 30 Oct 2019, In : BMJ Open. 9, 10, 031909.

Research output: Contribution to journalArticle

Open Access
File
Scientific Misconduct
Publications
Research
Clinical Trials
Guidelines
4 Citations (Scopus)

Annual ring growth of a widespread high arctic shrub reflects past fluctuations in community-level plant biomass

Le Moullec, M., Buchwal, A., Wal, R., Sandal, L. & Hansen, B. B., Jan 2019, In : Journal of Ecology. 107, 1, p. 436-451 16 p.

Research output: Contribution to journalArticle

Open Access
File
growth rings
Arctic region
shrub
shrubs
aboveground biomass
5 Citations (Scopus)

An online resource for marine fungi

Jones, E. B. G., Pang, K. L., Abdel-Wahab, M. A., Scholz, B., Hyde, K. D., Boekhout, T., Ebel, R., Rateb, M. E., Henderson, L., Sakayaroj, J., Suetrong, S., Dayarathne, M. C., Kumar, V., Raghukumar, S., Sridhar, K. R., Bahkali, A. H. A., Gleason, F. H. & Norphanphoun, C., May 2019, In : Fungal Diversity. 96, 1, p. 347-433 87 p.

Research output: Contribution to journalArticle

marine fungi
fungus
resource
Chytridiomycota
taxonomy

A novel external fixation method and its impact on wrist distraction in relation to distal radial fracture

Ashcroft, G. P., Murphy, L., Hanich, A. A., Downing, M., Van Niekerk, A. & Shahana, S., 21 Jun 2019, (Accepted/In press).

Research output: Contribution to conferenceAbstract

Wrist
Ligaments
Metacarpal Bones
Formaldehyde
Tantalum

Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin

Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K-M., Russell, W. R., Scobbie, L. & Hoggard, N., 31 Oct 2019, In : Journal of Functional Foods. 103597.

Research output: Contribution to journalArticle

Open Access
Vaccinium myrtillus
bilberries
Anthocyanins
volunteers
anthocyanins

Antibiotic prophylaxis for the prevention of infectious complications following prostate biopsy: A Systematic Review and Meta-analysis

Pilatz, A., Dimitropoulos, K., Veeratterapillay, R., Yuan, Y., Omar, M. I., MacLennan, S., Cai, T., Bruyère, F., Bartoletti, R., Köves, B., Wagenlehner, F., Bonkat, G. & Pradere, B., 11 Nov 2019, (Accepted/In press) In : Journal of Urology.

Research output: Contribution to journalArticle

Antibiotic Prophylaxis
Fluoroquinolones
Meta-Analysis
Prostate
Biopsy

Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., 16 Oct 2019, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 102024.

Research output: Contribution to journalArticle

Endocannabinoids
Ethanolamine
Cell growth
Breast Neoplasms
Derivatives

Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study

Grossi, C. M., Richardson, K., Fox, C., Maidment, I., Steel, N., Loke, Y. K., Arthur, A., Myint, P. K., Campbell, N., Boustani, M., Robinson, L., Brayne, C., Matthews, F. E. & Savva, G. M., 21 Oct 2019, In : BMC Geriatrics. 19, 10 p., 276.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Benzodiazepines
Dementia
Cohort Studies
Incidence
6 Downloads (Pure)

Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting

Ablett, A. D., Browning, A., Quan, V., Tay, H. S., McCormack, C., Carter, B., Hewitt, J., Myint, P. K. & Older Persons Surgical Outcomes Collaboration (OPSOC), Apr 2019, In : Asian Journal of Surgery. 42, 4, p. 527-534 8 p.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Emergencies
Patients' Rooms
Odds Ratio
Length of Stay
Open Access
comprehension
dialogue
discourse
experiment
Language
2 Citations (Scopus)

Antioxidant capacity is repeatable across years but does not consistently correlate with a marker of peroxidation in a free-living passerine bird

Récapet, C., Arrive, M., Doligez, B. & Bize, P., Apr 2019, In : Journal of Comparative Physiology B. 189, 2, p. 283-298 16 p.

Research output: Contribution to journalArticle

peroxidation
Birds
passerine
repeatability
antioxidant
1 Citation (Scopus)

Antioxidant effects of sulforaphane in human HepG2 cells and immortalised hepatocytes

Liu, P., Wang, W., Tang, J., Bowater, R. P. & Bao, Y., Jun 2019, In : Food and Chemical Toxicology. 128, p. 129-136 8 p.

Research output: Contribution to journalArticle

Hep G2 Cells
hepatocytes
Hepatocytes
Antioxidants
antioxidants
1 Citation (Scopus)

An update on Staphylococcus aureus infective endocarditis from the International Society of Antimicrobial Chemotherapy (ISAC)

Saeed, K., Bal, A., Gould, I., David, M. Z., Dryden, M., Giannitsioti, E., Hijazi, K., Meisner, J. A., Esposito, S., Scaglione, F., Tattevin, P. & Voss, A., Jan 2019, In : International Journal of Antimicrobial Agents. 53, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Open Access
File
Endocarditis
Staphylococcus aureus
Drug Therapy
Tricuspid Valve
Coagulase
6 Downloads (Pure)

Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves

Singh, A., Horsfield, M. A., Bekele, S., Greenwood, J. P., Dawson, D. K., Berry, C., Hogrefe, K., Kelly, D. J., Houston, J. G., Guntur Ramkumar, P., Uddin, A., Suzuki, T. & McCann, G. P., May 2019, In : European Radiology. 29, 5, p. 2340-2349 10 p.

Research output: Contribution to journalArticle

Open Access
File
Vascular Stiffness
Tricuspid Valve
Aortic Valve Stenosis
Mitral Valve
Pulse Wave Analysis

AP-2-dependent endocytic recycling of the chitin synthase Chs3 regulates polarized growth in Candida albicans

Knafler, H. C., Smaczynska-de Rooij, I. I., Walker, L. A., Lee, K. K., Gow, N. A. R. & Ayscougha, K. R., 19 Mar 2019, In : mBio. 10, 2, e02421-18.

Research output: Contribution to journalArticle

Open Access
Chitin Synthase
Candida albicans
Cell Wall
Growth
Hyphae

A Patient-Centered Description of Severe Asthma: Patient Understanding Leading to Assessment for a Severe Asthma Referral (PULSAR)

Winders, T. A., Wilson, A. M., Fletcher, M. J., McGuinness, A. & Price, D. B., Oct 2019, In : The Patient - Patient-Centered Outcomes Research. 12, 5, p. 539-549 11 p.

Research output: Contribution to journalArticle

Open Access
File
Referral and Consultation
Asthma
Checklist
Health Personnel
Terminology

A Physarum-Inspired Competition Algorithm for Solving Discrete Multi-Objective Optimization Problems

Awad, A., Usman, M., Lusseau, D., Coghill, G. M. & Pang, W., 13 Jul 2019, GECCO 2019 Companion - Proceedings of the 2019 Genetic and Evolutionary Computation Conference Companion. López-Ibáñez, M., Auger, A. & Stützle, T. (eds.). New York, USA: ACM, p. 195-196 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiobjective optimization
Cellular automata
Evolutionary algorithms

A pilot study to improve sugar and water consumption in Maltese school children

Copperstone, C., McNeill, G., Aucott, L. & Jackson, D. M., 15 Feb 2019, In : International Journal of Adolescent Medicine and Health.

Research output: Contribution to journalArticle

Drinking
Pediatric Obesity
Energy Intake
Health Promotion
Drinking Water

Appearance-based trust processing in schizophrenia

Sutherland, C. A. M., Rhodes, G., Williams, N., Connaughton, E., Ewing, L., Caruana, N. & Langdon, R., 6 Sep 2019, In : British Journal of Clinical Psychology.

Research output: Contribution to journalArticle

Schizophrenia
Experimental Games
Interpersonal Relations
Cues
Decision Making
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care

Application of Photogrammetry in Biomedical Science

Struck, R., Cordoni, S., Aliotta, S., Perez-Pachon, L. & Gröning, F., 2019, Biomedical Visualisation. Rea, P. M. (ed.). Springer , Vol. 1. p. 121-130 10 p. (Advances in Experimental Medicine and Biology; vol. 1120).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

photogrammetry
data quality
tomography
science
cost

Application of the Dynamic Gastrointestinal Simulator (simgi®) to assess the impact of probiotic supplementation in the metabolism of grape polyphenols

Gil-Sánchez, I., Cueva, C., Tamargo, A., Quintela, J. C., de la Fuente, E., Walker, A. W., Moreno-Arribas, M. V. & Bartolomé, B., 21 Nov 2019, In : Food Research International.

Research output: Contribution to journalArticle

Vitis
Probiotics
Polyphenols
Lactobacillus plantarum
probiotics

Appropriate age range for introduction of complementary feeding into an infant’s diet

Castenmiller, J., de Henauw, S., Hirsch-Ernst, K-I., kearney, J., Knutsen, H. K., Maciuk, A., Mangelsdorf, I., McArdle, H., Naska, A., Pelaez, C., Pentieva, K., Thies, F., Siani, A., Tsabouri, S., Vincenti, M., Bresson, J-L., Fewtrell, M., Kersting, M., Przyrembel, H., Dumas, C. & 3 others, Titz, A., Turck, D. & EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Sep 2019, In : EFSA Journal. 17, 9, 241 p., e5780.

Research output: Contribution to journalArticle

Open Access
File
Infant Nutritional Physiological Phenomena
infant feeding
complementary foods
Diet
Food
1 Downloads (Pure)

A qualitative study exploring the key determinants of information gathering to inform the management of over‐the‐counter (OTC) consultations in community pharmacies

Cassie, H., Duncan, E., Gibb, E., Power, A., Young, L., Newlands, R. & Watson, M. C. M., 20 Aug 2019, In : BMJ Open. 9, 8, e029937.

Research output: Contribution to journalArticle

Open Access
File
Pharmacies
Pharmacists
Referral and Consultation
Medicine
Professional Role

A randomized clinical study to evaluate the effect of denture adhesive application technique on food particle accumulation under dentures

Atassi, M., Milleman, K. R., Burnett, G. R., Sanyal, S. & Milleman, J. L., Aug 2019, In : Clinical and Experimental Dental Research. 5, 4, p. 316-325 10 p.

Research output: Contribution to journalArticle

Open Access
File
Dentures
Adhesives
Food
Denture Retention
Clinical Studies
1 Citation (Scopus)
5 Downloads (Pure)
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome
1 Citation (Scopus)
5 Downloads (Pure)

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., D'Santos, C., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., Mills, I. G., Carroll, J. S. & 5 others, Tilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 2019, In : Oncogene. 38, 7, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome
Open Access
File
Medical Schools
Information Storage and Retrieval
Internship and Residency
Medical Education
Medical Students
4 Citations (Scopus)
6 Downloads (Pure)

A retino-retinal projection guided by Unc5c emerged in species with retinal waves

Murcia-Belmonte, V., Coca, Y., Vegar, C., Negueruela, S., de Juan, C., Valiño, A. J., Sala, S., DaSilva, R., Kania, A., Borrell, V., Martinez, L. M., Erskine, L. & Herrera, E., Apr 2019, In : Current Biology. 29, 7, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

Open Access
File
axons
Axons
retina
Retina
Retinal Ganglion Cells
2 Citations (Scopus)

A Review of Criticisms of Integrated Assessment Models and Proposed Approaches to Address These, through the Lens of BECCS

Gambhir, A., Butnar, I., Li, P-H., Smith, P. & Strachan, N., 8 May 2019, In : Energies. 12, 9, 21 p., 1747.

Research output: Contribution to journalReview article

Open Access
File

A Review of International Biobanks and Networks: Success Factors and Key Benchmarks—A 10-Year Retrospective Review

Devereux, L., Watson, P. H., Mes-Massons, A-M., Crespo, F. D. L., Thomas, G., Pitman, H., Speirs, V., Hall, A. G., Bollinger, N., Posada, M., Lochmüller, H., Thorne, H., Eng, C. B., Riegman, P. H. J., Ng, W. & Parry Jones, A., 7 Nov 2019, (Accepted/In press) In : Biopreservation and Biobanking. 17, 6

Research output: Contribution to journalArticle

Anniversaries and Special Events