Life Sciences & Medicine

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Research Output 1970 2019

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2019

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., 10 Apr 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Open Access
Retinoic Acid Receptors
AMPA Receptors
Glutamate Receptors
Tretinoin
Ligands
1 Downloads (Pure)

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 3 Apr 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

Research output: Contribution to journalArticle

Open Access
File
Luminescent Proteins
Optical Imaging
Fungi
Fungal Proteins
Mycoses

A case-note review of continued pregnancies found to be at a high risk of Huntington’s disease: considerations for clinical practice

on behalf of the UK Huntington’s Disease Predictive Testing Consortium, Wadrup, F., Holden, S., MacLeod, R., Miedzybrodzka, Z., Németh, A. H., Owens, S., Pasalodos, S., Quarrell, O. & Clarke, A. J., 19 Mar 2019, In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Huntington Disease
Pregnancy
High-Risk Pregnancy
Prenatal Care
Confidentiality
1 Citation (Scopus)

Accumulation of nitrate and dissolved organic nitrogen at depth in a red soil Critical Zone

Wu, H., Song, X., Zhao, X., Peng, X., Zhou, H., Hallett, P. D., Hodson, M. E. & Zhang, G. L., 1 Mar 2019, In : Geoderma. 337, p. 1175-1185 11 p.

Research output: Contribution to journalArticle

dissolved organic nitrogen
red soil
regolith
nitrates
nitrate

Accuracy of gonadosomatic index in maturity classification and estimation of maturity ogive

Flores, A., Wiff, R., Ganias, K. & Marshall, C. T., Feb 2019, In : Fisheries Research. 210, p. 50-62 13 p.

Research output: Contribution to journalArticle

Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: Protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma

Murchie, P., Masthoff, J., Walter, F. M., Rahman, K., Allan, J. L., Burrows, N., Proby, C., Lee, A. J., Johnston, M., Durrani, A., Depasquale, I., Brant, B., Neilson, A., Meredith, F., Treweek, S. P., Hall, S. J. & McDonald, A. M., 18 May 2019, (Accepted/In press) In : Trials.

Research output: Contribution to journalArticle

Aftercare
Melanoma
Self-Examination
Neoplasms
Skin

A comparison of professional and private time preferences of General Practitioners

Irvine, A., Van der Pol, M. & Phimister, E., 1 Feb 2019, In : Social Science & Medicine. 222, p. 256-264 9 p.

Research output: Contribution to journalArticle

general practitioner
General Practitioners
Patient Preference
Health
Likelihood Functions

A conceptual framework for patient-directed knowledge tools to support patient-centred care: Results from an evidence-informed consensus meeting

Dreesens, D., Stiggelbout, A., Agoritsas, T., Elwyn, G., Flottorp, S., Grimshaw, J., Kremer, L., Santesso, N., Stacey, D., Treweek, S., Armstrong, M., Gagliardi, A., Hill, S., Légaré, F., Ryan, R., Vandvik, P. & van der Weijden, T., 4 May 2019, (Accepted/In press) In : Patient Education and Counseling.

Research output: Contribution to journalArticle

Consensus
Self Care
Decision Making

A critical review of the impacts of cover crops on nitrogen leaching, net greenhouse gas balance and crop productivity

Abdalla, M., Hastings, A., Cheng, K., Yue, Q., Chadwick, D., Espenberg, M., Truu, J., Rees, R. M. & Smith, P., 7 Apr 2019, In : Global Change Biology.

Research output: Contribution to journalArticle

Open Access
cover crop
Greenhouse gases
Leaching
Crops
greenhouse gas

Activity energy expenditure is an independent predictor of energy intake in humans

Hopkins, M., Duarte, C., Beaulieu, K., Finlayson, G., Gibbons, C., Johnstone, A., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 18 Jan 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Energy Intake
Energy Metabolism
Basal Metabolism
Body Composition
Diet Records

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Glutathione
Zinc

Addressing medication errors in an adult oncology department in Saudi Arabia: A qualitative study

Alharbi, W., Cleland, J. & Morrison, Z., 19 Mar 2019, In : Saudi Pharmaceutical Journal.

Research output: Contribution to journalArticle

Open Access
Medication Errors
Saudi Arabia
Communication
Delivery of Health Care
Education
Dental Schools
Crowns
Tongue
Tooth
Students

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

Vickers, M. A., Jan 2019, In : Cells. 8, 1, doi: 10.3390/cells8010047.

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cell Transplantation
Virus Diseases
Cell- and Tissue-Based Therapy
Viruses
T-Lymphocytes
1 Citation (Scopus)
2 Downloads (Pure)

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
File
Age of Onset
Walking
Hip
Walkers
Femur Neck

Age-length relationships in UK harbour seals during a period of population decline

Hall, A. J., Mackey, B., Kershaw, J. L. & Thompson, P., 24 Feb 2019, (Accepted/In press) In : Aquatic Conservation: Marine and Freshwater Ecosystems.

Research output: Contribution to journalArticle

Phoca vitulina
population decline
harbor
coast
Scotland
1 Downloads (Pure)

A global, empirical, harmonised dataset of soil organic carbon changes under perennial crops

Ledo, A., Hillier, J., Smith, P., Aguilera, E., Blagodatskiy, S., Brearley, F. Q., Datta, A., Diaz-Pines, E., Don, A., Dondini, M., Dunn, J., Feliciano, D., Lang, R., Liebig, M. A., Llorente, M., Zinn, Y. L., McNamara, N., Ogle, S. M., Qin, Z., Rovira, P. & 5 othersRowe, R., Vicente-Vicente, J. L., Whitaker, J., Yue, Q. & Zerihun, A., 13 May 2019, In : Scientific Data. 6, 57.

Research output: Contribution to journalArticle

Open Access
File
Organic carbon
Crops
Soil
Carbon
bioenergy

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C-D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Muller, B. & Connolly, B., 5 Apr 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression

A literature review of the predictive validity of European dental school selection methods

Cunningham, C., Patterson, F. & Cleland, J., May 2019, In : European Journal of Dental Education. 23, 2, p. 73-87 15 p.

Research output: Contribution to journalArticle

Dental Schools
Aptitude
school
Dentistry
Research
1 Citation (Scopus)

Allometry of fine roots in forest ecosystems

Chen, G., Hobbie, S. E., Reich, P. B., Yang, Y. & Robinson, D., Feb 2019, In : Ecology Letters. 22, 2, p. 322-331 10 p.

Research output: Contribution to journalArticle

allometry
fine root
forest ecosystems
forest ecosystem
biomass
2 Downloads (Pure)

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler, P., 14 Feb 2019, In : PLoS Biology. 17, 2, e3000002.

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens

AMEE guide no. 123 - How to read studies of educational costs

Maloney, S., Cook, D. A., Golub, R., Foo, J., Cleland, J., Rivers, G., Tolsgaard, M. G., Evans, D., Abdalla, M. E. & Walsh, K., 2019, In : Medical Teacher. p. 1-8 8 p.

Research output: Contribution to journalArticle

decision making
costs
opportunity costs
economics
decision maker

A methodology for creating and validating psychological stories for conveying and measuring psychological traits

Smith, K. A., Dennis, M., Masthoff, J. & Tintarev, N., 19 Mar 2019, In : User Modeling and User-Adapted Interaction. p. 1–46

Research output: Contribution to journalArticle

Open Access
Recommender systems
Conveying
Intelligent systems
personality
methodology

A model for spatio-temporal injury surveillance: implications for the evolution of a trauma system

Jansen, J. O., Emerson, P., Morrison, J. J. & Cornulier, T., Feb 2019, In : The journal of trauma and acute care surgery. 86, 2, p. 289-298 10 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Scotland
Hebrides
Islands
Population

An advantage for horizontal motion direction discrimination

Pilz, K. S. & Papadaki, D., May 2019, In : Vision Research. 158, p. 164-172 9 p.

Research output: Contribution to journalArticle

Direction compound
Individuality
1 Downloads (Pure)
Open Access
File
Antigen Receptors
Transgenic Mice
Autoimmune Diseases
Arthritis
Tumor Necrosis Factor-alpha
3 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 8 May 2019, (Accepted/In press) In : Frontiers in Microbiology.

Research output: Contribution to journalArticle

Open Access
Mycoses
Skin
Infection
Microscopy
Animal Models
Streptomyces griseus
Lactalbumin
Pronase
lactalbumin
enzymatic treatment
2 Citations (Scopus)

Annual ring growth of a widespread high arctic shrub reflects past fluctuations in community-level plant biomass

Le Moullec, M., Buchwal, A., Wal, R., Sandal, L. & Hansen, B. B., Jan 2019, In : Journal of Ecology. 107, 1, p. 436-451 16 p.

Research output: Contribution to journalArticle

growth rings
Arctic region
shrub
shrubs
aboveground biomass
1 Downloads (Pure)

Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting

Ablett, A. D., Browning, A., Quan, V., Tay, H. S., McCormack, C., Carter, B., Hewitt, J., Myint, P. K. & Older Persons Surgical Outcomes Collaboration (OPSOC), Apr 2019, In : Asian Journal of Surgery. 42, 4, p. 527-534 8 p.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Emergencies
Patients' Rooms
Odds Ratio
Length of Stay

Antioxidant capacity is repeatable across years but does not consistently correlate with a marker of peroxidation in a free-living passerine bird

Récapet, C., Arrive, M., Doligez, B. & Bize, P., Apr 2019, In : Journal of Comparative Physiology B. 189, 2, p. 283-298 16 p.

Research output: Contribution to journalArticle

peroxidation
Birds
passerine
repeatability
antioxidant

An update on Staphylococcus aureus infective endocarditis from the International Society of Antimicrobial Chemotherapy (ISAC)

Saeed, K., Bal, A., Gould, I., David, M. Z., Dryden, M., Giannitsioti, E., Hijazi, K., Meisner, J. A., Esposito, S., Scaglione, F., Tattevin, P. & Voss, A., Jan 2019, In : International Journal of Antimicrobial Agents. 53, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Endocarditis
Staphylococcus aureus
Drug Therapy
Tricuspid Valve
Coagulase

A pilot study to improve sugar and water consumption in Maltese school children

Copperstone, C., McNeill, G., Aucott, L. & Jackson, D. M., 15 Feb 2019, In : International Journal of Adolescent Medicine and Health.

Research output: Contribution to journalArticle

Drinking
Pediatric Obesity
Energy Intake
Drinking Water
Parents
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care
1 Citation (Scopus)
2 Downloads (Pure)

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., D'Santos, C., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., Mills, I. G., Carroll, J. S. & 5 othersTilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 2019, In : Oncogene. 38, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome

A retino-retinal projection guided by Unc5c emerged in species with retinal waves

Murcia-Belmonte, V., Coca, Y., Vegar, C., Negueruela, S., de Juan, C., Valiño, A. J., Sala, S., DaSilva, R., Kania, A., Borrell, V., Martinez, L. M., Erskine, L. & Herrera, E., Apr 2019, In : Current Biology. 29, 7, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

Open Access
File
axons
Axons
retina
Diencephalon
Artifacts
Open Access
File
diversification
Crops
Sustainable development
poverty
sustainable development
Dietetics
Prostatic Neoplasms
Randomized Controlled Trials
Exercise
Weights and Measures

Assessment of numerical methods for fully resolved simulations of particle-laden turbulent flows

Brändle de Motta, J. C., Costa, P., Derksen, J. J., Peng, C., Wang, L-P., Breugem, W-P., Estivalezes, J. L., Vincent, S., Climent, E., Fede, P., Barbaresco, P. & Renon, N., 30 Jan 2019, In : Computers & Fluids. 179, p. 1-14 14 p.

Research output: Contribution to journalArticle

Turbulent flow
Numerical methods
Turbulence
Kinetic energy
Fluids

Association between hours worked in paid employment and diet quality, frequency of eating out and having takeaways in the UK

Sam, L., Craig, T., Macdiarmid, J. & Horgan, G., 17 May 2019, (Accepted/In press) In : Public Health Nutrition.

Research output: Contribution to journalArticle

Open Access
File
Eating
Food
Linear Models
Diet Surveys
Logistic Models
Ankylosing Spondylitis
Biological Products
Smoking
Fatigue
Sleep

A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements

Huang, I., Mak, D., Cheung, P., Abraham, M., Clemens, T. & Turner, S., 8 Apr 2019, In : Environmental Research. 173, p. 528-538 11 p.

Research output: Contribution to journalArticle

Maternal Exposure
smoking
pregnancy
Nitrogen Dioxide
Smoking
1 Citation (Scopus)
62 Downloads (Pure)
Open Access
File
Color
experiment
Uncertainty
activation
uncertainty

A wetland ecosystem service assessment tool: Development and application in a tropical peatland in Uganda

Langan, C., Farmer, J., Rivington, M., Novo, P. & Smith, J. U., 18 Apr 2019, In : Ecological Indicators. 103, p. 434-445 12 p.

Research output: Contribution to journalArticle

peatlands
Uganda
peatland
ecosystem service
ecosystem services

AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS)

MacFarlane, G. J., Pathan, E., Siebert, S., Packham, J., Gaffney, K., Choy, E. H., Sengupta, R., Atzeni, F., Martin, K. R., Jones, G. T. & Dean, L., 25 Apr 2019, (Accepted/In press) In : BMC Rheumatology.

Research output: Contribution to journalArticle

1 Downloads (Pure)

Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn's Disease

Delday, M., Mulder, I., Logan, E. T. & Grant, G., 1 Jan 2019, In : Inflammatory Bowel Diseases. 25, 1, p. 85-96 11 p.

Research output: Contribution to journalArticle

Open Access
File
Crohn Disease
Inflammatory Bowel Diseases
Dextran Sulfate
Inflammation
Weight Loss
Molecular Pathology
National Cancer Institute (U.S.)
Clinical Trials
Pathology
Research