Research Output per year
Research Output 1970 2020
- 1 - 50 out of 68 results
- Publication Year, Title (descending)
2019
Synthetic Retinoids for Use in RAR Mediated Conditions
Whiting, A., Chisholm, D., Valentine, R., Greig, I. R., McCaffery, P. J. A. & Alkhatib, T., 18 Apr 2019, IPC No. C07C 63/66, A61K 31/192, A61K 31/203, A61P 25/28, C07D 209/82, C07D 215/06, European Patent Office, Patent No. WO2017174999, Priority date 6 Apr 2017, Priority No. 2017050977Research output: Patent
Retinoids
2017
Synthetic retinoids for use in RAR mediated conditions
Greig, I. R., McCaffery, P. J. A., Whiting, A., Valentine, R., Chisholm, D. & Khatib, T., 12 Oct 2017, Patent No. WO2017174999Research output: Patent
Retinoids
2016
7
Downloads
(Pure)
Enhanced RNAI Mediated Gene Regulation
Bowman, A. S., Campbell, E. M. & Lewendon, A., 14 Jul 2016, IPC No. A61K31/7088; C12N15/113, Patent No. WO2016110691 (A1) , Priority date 6 Jan 2015, Priority No. GB20150000107 20150106Research output: Patent
Open Access
File
Nucleic Acids
Host-Parasite Interactions
Disclosure
Genes
Parasites
N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-PHENYL-BENZENESULFONAMIDE AND N-(4-HYDROXY-4-METHYL-CYCLOHEXYL)-4-(2-PYRIDYL)-BENZENESULFONAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE
Smith, S., Patel, L. & Greig, I. R., 23 Jun 2016, Patent No. WO2016/097001, Priority date 17 Dec 2014Research output: Patent
PATENT: Antibody molecules and uses thereof.
Gow, N. A. R., Rudkin, F. M., Erwig, L-P. & Jensen, A., 15 Sep 2016, IPC No. C07K 16/14 , G01N 33/53, World Intellectual Property Organization, Patent No. WO 2016/142660 Al, 4 Mar 2016, Priority date 6 Mar 2015, Priority No. GB 1503812.8Research output: Patent
Antibodies
Candida
Fungal Antigens
Gene Targeting
Cell Extracts
2015
Phenothiazine compounds for treating mild cognitive impairment
Wischik, C. M., Harbaran, D. V., Riedel, G., Deiana, S., Goatman, E. A., Wischik, D. J., Murray, A. D. & Staff, R. T., 15 Dec 2015, Patent No. US9211294, 17 Jun 2008, Priority date 19 Jun 2007, Priority No. 60/945006Research output: Patent
Cognitive Dysfunction
phenothiazine
Polyethylene glycol derivatives of palmitoylethanolamide and analogous acylethanolamides
D'Agostino, G., 13 Jun 2015, Patent No. CA2836069 A1, Priority date 13 Dec 2012Research output: Patent
2014
1
Downloads
(Pure)
Fish Vaccine
Wawra, S., Van West, P. & Secombes, C. J., 4 Dec 2014, IPC No. A61K38/16; C07K14/37; C12N15/62, Patent No. WO2014191759, Priority date 30 May 2013, Priority No. GB20130009664 20130530Research output: Patent
vaccines
fish
nucleic acids
eukaryotic cells
plasma membrane
Fluoro-perhexiline compounds and their therapeutic use
Greig, I. R., Tseng, C-C. & Zanda, M., 30 Oct 2014, Patent No. WO2014184561Research output: Patent
ISOLATION OF THERAPEUTIC TARGET SPECIFIC VNAR DOMAINS TO ICOSL
Barelle, C., Finlay, J. J. W. & Darmanin-Sheehan, A., 30 Oct 2014, IPC No. C07K16/00; C07K16/18; C12N15/13, Priority date 23 Apr 2013, Priority No. US201361815043P 20130423Research output: Patent
Antigen Receptors
Libraries
Sharks
Ligands
Squalus acanthias
N-(4-Hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and N-(4-Hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzene sulfonamides and their therapeutic use
Patel, L., Smith, S., Greig, I. R. & Williams, S., 2014, Patent No. WO2014207445Research output: Patent
2013
18f-labelled barbiturate compounds for use as positron emission imaging agents
Greig, I. R., Zanda, M., Platt, B. & Calamai, E., 21 Mar 2013, Patent No. WO2013038153Research output: Patent
Aryl-Phenyl-Sulfonamido-Cycloalkyl Compounds and Their Use
Greig, I. R., Sheridan, R. M., Fisher, R., Tozer, M. J., Clase, J. A., Smith, A., Tufnell, A. R. & van 't Hof, R. J., 19 Sep 2013, Patent No. US2013245018Research output: Patent
Bone and Bones
Rheumatoid Arthritis
Anistreplase
Bone Neoplasms
Psoriatic Arthritis
4
Downloads
(Pure)
SINGLE DOMAIN BINDING MOLECULE
Barelle, C., Muller, M., Calabro, V., Bikker, J., Steven, J., Tchistiakova, L., Kovalenko, O. V. & Olland, A., 14 Nov 2013, IPC No. C07K16/46, Priority No. US201313889134 20130507 ; US201261643407P 20120507Research output: Patent
Open Access
File
Complementarity Determining Regions
Patents and inventions
Serum Albumin
Amino Acids
Molecules
2
Downloads
(Pure)
USE OF PLATELET GLYCOPEPTIDE IIIA EPITOPES IN THE TREATMENT OF IMMUNE THROMBOCYTOPENIC PURPURA
Urbaniak, S., Barker, R. N. & Sukati, H. M., 27 Mar 2013, IPC No. A61K38/10; A61P7/00, Patent No. EP2120992, Priority date 18 Jan 2007, Priority No. GB0701048Research output: Patent
Open Access
Idiopathic Thrombocytopenic Purpura
Glycopeptides
Epitopes
Blood Platelets
Autoantibodies
2012
New phenothiazine diaminium compounds are tau protein aggregation inhibitors, useful to treat e.g. Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia and frontotemporal lobar degeneration syndromes
Baddeley, T., Clunas, S., Harrington, C. R., Horsley, D., Ishaq, A., Khan, K., Loh, Y. S., Marshall, C., Rickard, J. E., Simpson, M., Sinclair, J. P., Storey, J. M. D., Williamson, C., Wischik, C. M. & Wood, B. A., 16 Aug 2012, Patent No. WO2012107706-A1, Priority date 11 Feb 2011Research output: Patent
tau Proteins
Agglomeration
Purification
Salts
phenothiazine
2011
6
Downloads
(Pure)
3,7-diamino-10H-phenothiazine salts and their use: WO2007110627
Wischik, C. M., Rickard, J. E., Harrington, C. R., Horsley, D., Storey, J. M. D., Marshall, C., Sinclair, J. P. & Baddeley, T., 15 Feb 2011, Patent No. US7,888,350Research output: Patent
File
Salt
Drugs
Alzheimer's Disease
Invention
Bone Graft System
Gibson, I. R., Skakle, J., Annaz, B. & Conway, J., 29 Dec 2011, IPC No. A61L27/46, Patent No. WO2011GB00939Research output: Patent
Hydrogel
Silicon
Grafts
Bone
Durapatite
16
Downloads
(Pure)
Methods and Feed Compositions for Masking of Fish Semiochemicals
Wadsworth, S., Vecino, J. L. G., Pino, J. & Mordue, A. J., 9 Jun 2011, IPC No. A23K1/16; A23K1/18 (2006.1), Priority date 2 Dec 2009, Priority No. NO20090003460 20091202Research output: Patent
Open Access
File
Pheromones
Fishes
Parasitic Diseases
Parasites
Water
N-(ARYLALKYL)-1H-INDOLE-2-SULFONIC ACID AMIDE COMPOUNDS AND THEIR THERAPEUTIC USE AS CANNABINOID ALLOSTERIC MODULATORS
Greig, I. R., Ross, R. A., Trembleau, L. A. C., Pertwee, R. G. & Abdelrahman, M. H., 28 Feb 2011, IPC No. WO2012117216, Patent No. WO2012117216Research output: Patent
Cannabinoid Receptors
Sulfonic Acids
Cannabinoids
Therapeutic Uses
Amides
Synthesis of Bioceramic Compositions
Gibson, I. R. & Skakle, J., 27 Jan 2011, IPC No. A61L27/12, Patent No. US20110021338Research output: Patent
Bioceramics
Calcium
Chemical analysis
Alkalies
Silicon
2010
1,5-Diaryl-pyrazoles and their use as cannabinoid receptor neutral antagonists
Greig, I. R. & Ross, R. A., 25 Feb 2010, IPC No. WO2010020762, Patent No. WO2010020762Research output: Patent
Pyrazoles
Cannabinoid Receptor Antagonists
Cannabinoid Receptors
Breast Neoplasms
Smoking
3,6-Disubstituted xanthylium salts
Clunas, S., Storey, J. M. D., Horsley, D., Rickard, J. E., Harrington, C. R. & Wischik, C. M., 17 Jun 2010, IPC No. WO2010/067078Research output: Patent
Patents and inventions
Salts
Pharmaceutical Preparations
xanthylium
A method of remediating contaminated water and apparatus for the same
Killham, K. S., Paton, G. I. & Cassidy, L., 21 Jul 2010, Patent No. EP2207633Research output: Patent
27
Downloads
(Pure)
Antibodies specifically directed to a soluble form of CTLA-4
Ward, F. J., Barker, R. N. & Dahal, L. N., 2 Sep 2010, Patent No. US8697845 B2, Priority date 15 Apr 2014Research output: Patent
Open Access
File
HLA-D Antigens
Antibodies
19
Downloads
(Pure)
Antigen Binding Domains from Fish
Dooley, H., Porter, A. J. R. & Flajnik, M. F., 3 Mar 2010, IPC No. C07K 16/00; 16/18; 15/63, Patent No. 1419179, Priority date 10 Aug 2001, Priority No. GB0119553; GB0210508Research output: Patent
Open Access
File
Fish
Antigens
Immunoglobulin Isotypes
DNA sequences
Aryl-phenyl-sulfonamide-cycloalkyl compounds and their use
Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J. & Tufnell, A. R., 25 Mar 2010, IPC No. WO2010/032009 , Patent No. WO2010/032009Research output: Patent
2
Downloads
(Pure)
Aryl-phenyl-sulfonamide-phenylene compounds and their use
Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J., Tufnell, A. R. & van 't Hof, R. J., 25 Mar 2010, IPC No. WO2010/032010, Patent No. WO2010/032010Research output: Patent
File
Sulfonamides
Bone and Bones
Rheumatoid Arthritis
Bone Neoplasms
Psoriatic Arthritis
Biomedical materials
Gibson, I. R., Skakle, J., Smith, N. & Buckland, T., 23 Dec 2010, IPC No. A61K49/06, Patent No. US20100322867Research output: Patent
gadolinium
calcium
phosphate
material
chemical
7
Downloads
(Pure)
Ligands for aggregated tau molecules: WO2010034982
Kemp, S. J., Storey, J. M. D., Rickard, J. E., Harrington, C. R., Horsley, D., Wischik, C. M., Clunas, S. & Heinrich, T., 1 Apr 2010, Patent No. WO2010/034982Research output: Patent
File
tau Proteins
Hydrates
Labels
Salts
Ligands
Materials and methods for medical imaging
Smith, T. A. D., Trembleau, L. A. C., McLaughlin, A. & Simpson, M., 2010, IPC No. WO2009056837, Patent No. GB2467494 (A)Research output: Patent
positrons
inventions
marking
emitters
platforms
Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC): methods of treatment of a tauopathy condition comprising the use of thioninium compounds
Wischik, C. M., Rickard, J. E., Harrington, C. R., Horsley, D., Storey, J. M. D., Marshall, C. & Sinclair, J. P., 15 Jun 2010, Patent No. US7,737,138Research output: Patent
Methylene Blue
Purification
Patents and inventions
Thiosulfonic Acids
Chlorides
Silicate-substituted hydroxyapatite
Gibson, I. R. & Skakle, J., 8 Jul 2010, IPC No. A61L27/12, Patent No. US20100173009Research output: Patent
Silicates
Durapatite
Carbonates
Biocompatible Materials
Silicon
9
Downloads
(Pure)
Vision Exercising Apparatus
Sahraie, A., 10 Jun 2010, IPC No. A61H 5/00; A61B 3/024, Priority date 17 Apr 2008, Priority No. 0513603.1Research output: Patent
Open Access
File
Display devices
Position control
2009
Apparatus for Variable Cycling the Water Depth in a Tank
Fraser, P. & Smith, L., 2009Research output: Patent
Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions
Greig, I. R., Ralston, S., Idris, A. I. & Van't Hof, R. J., 2009, Patent No. US7598289Research output: Patent
Methods of synthesis and/or purification of diaminophenothiazinium compounds
Wischik, C. M., Storey, J. M. D., Marshall, C., Sinclair, J. P. & Baddeley, T., 2009, Patent No. EP2057136Research output: Patent
Neuroprotective 3-phenylacrylonitrile (3-PAN) derivatives
Greig, I. R., Teismann, P., Hanisch, U-K. & Bruck, W., 16 Sep 2009, IPC No. GB2458259, Patent No. GB2458259Research output: Patent
Derivatives
Hydrogen
Neurodegenerative diseases
Chemical analysis
Pharmaceutical Preparations
New pharmaceutical formulation comprising cannabidiol and tetrahydrocannabivarin
Pertwee, R. G., Guy, G. W. & Whittle, B., 15 Jan 2009, IPC No. A61K31/05; A61K31/352; A61K36/185; A61P19/08;, Patent No. WO2009007697Research output: Patent
Cannabidiol
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Drug Compounding
Cannabinoids
2
Downloads
(Pure)
Therapeutic Use of Diaminophenothiazines: WO2009044127
Wischik, C. M., Damon J., W., Storey, J. M. D. & Harrington, C. R., 9 Apr 2009, IPC No. WO2009/044127Research output: Patent
File
Dosage Forms
Therapeutic Uses
Pharmacokinetics
Treatment and Diagnosis of Behavioural Disorders
Miedzybrodzka, Z. H., St Clair, D. M., Muller, B. M., Neves-Pereira, M. D. L. & Massie, D., 2009, IPC No. C12Q 1/68 (2006.01), Patent No. WO/2009/144480Research output: Patent
Pharmaceutical Preparations
US20120107320 - Antibodies specifically directed to the soluble form of CTLA-4
Ward, F. J., Barker, R. N. & Dahal, L. N., 28 Feb 2009, IPC No. US20120107320Research output: Patent
HLA-D Antigens
Antibodies
Use of tetrahydrocannabinol and/or cannabidiol for the treatment of inflammatory bowel disease
Pertwee, R. G., Guy, G. W., Jamontt, J. & Robson, P., 8 Jan 2009, IPC No. A61K31/05; A61K31/352; A61K36/185; A61P19/08; , Patent No. WO2009004302Research output: Patent
Cannabidiol
Dronabinol
Inflammatory Bowel Diseases
Cannabinoids
2008
[11C]Methoxy-radiolabelled 2,3',4,5' - Tetramethoxystilbene (TMS) and its preparation and use8
Schweiger, L. & Smith, T. A. D., 2008, Patent No. WO2009001046Research output: Patent
1,5-diaryl-pyrazoles as cannabinoid receptor neutral antagonists useful as therapeutic agents
Greig, I. R., Ross, R. A. & Pertwee, R. G., 21 Aug 2008, IPC No. A61K31/415; A61P29/00; C07D231/12; , Patent No. WO2008/099139Research output: Patent
Pyrazoles
Cannabinoid Receptor Antagonists
Cognition
Smoking
Osteitis Deformans
2',4'-Dichloro-biphenyl-4-yl-hydroxyketones and related compounds and their use as therapeutic agents
Greig, I. R., Van T Hof, R. J. & Ralston, S., 11 Sep 2008, IPC No. US20080221220, Patent No. US20080221220Research output: Patent
Biphenyl-4-yl-sulfonic acid arylamines and their use as therapeutic agents
Greig, I. R., van't Hof, R. J. & Ralston, S., 2008, Patent No. WO2008/114022Research output: Patent
Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions
Greig, I. R., Ralston, S., Van T Hof, R. J. & Mohamed, A. I. I., 18 Dec 2008, IPC No. US7598289, Patent No. US7598289Research output: Patent
New use for cannabinoid
Pertwee, R. G. & Guy, G. W., 21 Oct 2008, IPC No. A61K31/00; A61K31/33; A61K31/454; , Patent No. BRPI0518011Research output: Patent
Cannabinoid Receptor CB1
Cannabinoids
Obesity
Cannabinoid Receptor Antagonists
Appetite Depressants
Therapeutic uses of cannabigerol
Pertwee, R. G., 31 Dec 2008, IPC No. A61K31/352; A61K36/185; A61P25/28; (+3), Patent No. WO2009001081Research output: Patent
Therapeutic Uses
Brain Injuries
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Cachexia