Research Output 1970 2020

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Review article
2019
3 Citations (Scopus)

Recent trends in molecular diagnostics of yeast infections: from PCR to NGS

Gabaldón, T., Buda De Cesare, G., Munro, C. A. & OPATHY Consortium, Sep 2019, In : FEMS Microbiology Reviews. 43, 5, p. 517-547 31 p.

Research output: Contribution to journalReview article

Open Access
File
Molecular Pathology
Yeasts
Polymerase Chain Reaction
Infection
Opportunistic Infections
2 Citations (Scopus)

Targeting anti-chondrogenic factors for the stimulation of chondrogenesis: A new paradigm in cartilage repair

Lolli, A., Colella, F., De Bari, C. & van Osch, G. J. V. M., 31 Jan 2019, In : Journal of Orthopaedic Research. 37, 1, p. 12-22 11 p.

Research output: Contribution to journalReview article

Chondrogenesis
Cartilage
Mesenchymal Stromal Cells
Investigational Therapies
Wounds and Injuries

The intersection of host and fungus through the zinc lens

Wilson, D. & Deepe, G. S., 1 Dec 2019, In : Current Opinion in Microbiology. 52, p. 35-40 6 p.

Research output: Contribution to journalReview article

Lenses
Zinc
Fungi
Leukocyte L1 Antigen Complex
Metallothionein

The potential of respiration inhibition as a new approach to combat human fungal pathogens

Duvenage, L., Munro, C. A. & Gourlay, C. W., Dec 2019, In : Current Genetics. 65, 6, p. 1347-1353 7 p.

Research output: Contribution to journalReview article

Open Access
File
Respiration
Virulence
Electron Transport
Mitochondria
Hyphae

Wiring the Binocular Visual Pathways

Murcia-Belmonte, V. & Erskine, L., 4 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, 3282.

Research output: Contribution to journalReview article

Open Access
File
Binoculars
Visual Pathways
wiring
Retinal Ganglion Cells
axons
2018
4 Citations (Scopus)
5 Downloads (Pure)

An Invertebrate Host to Study Fungal Infections, Mycotoxins and Antifungal Drugs: Tenebrio molitor

Canteri de Souza, P., Custódio Caloni, C., Wilson, D. & Sergio Almeida, R., 12 Nov 2018, In : Journal of Fungi. 4, 4, 125.

Research output: Contribution to journalReview article

Open Access
File
Tenebrio
Mycoses
Mycotoxins
Invertebrates
Larva
8 Citations (Scopus)
6 Downloads (Pure)

Antifungal innate immunity: a perspective from last 10 years

Salazar, F. & Brown, G. D., 2018, In : Journal of Innate Immunity. 10, p. 373-397 24 p.

Research output: Contribution to journalReview article

Open Access
File
Innate Immunity
Fungal Drug Resistance
Opportunistic Infections
Immunity
Fungi
3 Citations (Scopus)
9 Downloads (Pure)

C-Type Lectin Receptors in Asthma

Hadebe, S., Brombacher, F. & Brown, G. D., 11 Apr 2018, In : Frontiers in Immunology. 9, p. 1-11 11 p., 733.

Research output: Contribution to journalReview article

Open Access
File
C-Type Lectins
Allergens
Asthma
Dermatophagoides Antigens
Peptide Initiation Factors
19 Citations (Scopus)
3 Downloads (Pure)

Dynamic Fungal Cell Wall Architecture in Stress Adaptation and Immune Evasion

Hopke, A., Brown, A. J. P., Hall, R. A. & Wheeler, R. T., Apr 2018, In : Trends in Microbiology. 26, 4, p. 284-295 12 p.

Research output: Contribution to journalReview article

Open Access
File
Immune Evasion
Cell Wall
Fungal Polysaccharides
Modern 1601-history
Mycoses
4 Citations (Scopus)
4 Downloads (Pure)

GPCRs in pulmonary arterial hypertension: tipping the balance

Iyinikkel, J. & Murray, F., Aug 2018, In : British Journal of Pharmacology. 175, 15, p. 3063-3079 17 p.

Research output: Contribution to journalReview article

Open Access
File
Pulmonary Hypertension
Pulmonary Artery
Smooth Muscle Myocytes
Blood Vessels
Lung
7 Citations (Scopus)
5 Downloads (Pure)

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

Dijck, P. V., Sjollema, J., Cammue, B. P. A., Lagrou, K., Berman, J., d'Enfert, C., Andes, D. R., Arendrup, M. C., Brakhage, A. A., Calderone, R., Cantón, E., Coenye, T., Cos, P., Cowen, L. E., Edgerton, M., Espinel-Ingroff, A., Filler, S. G., Ghannoum, M., Gow, N. A. R., Haas, H. & 19 others, Jabra-Rizk, M. A., Johnson, E. M., Lockhart, S. R., López-Ribot, J. L., Maertens, J., Munro, C. A., Nett, J. E., Nobile, C. J., Pfaller, M. A., Ramage, G., Sanglard, D., Sanguinetti, M., Spriet, I., Verweij, P. E., Warris, A., Wauters, J., Yeaman, M. R., Zaat, S. A. J. & Thevissen, K., Jul 2018, In : Microbial Cell. 5, 7, p. 300-326 27 p.

Research output: Contribution to journalReview article

Open Access
File
Antifungal Agents
Biofilms
Mycoses
Mycology
Disease Management
4 Citations (Scopus)
3 Downloads (Pure)

On the Road to Immunotherapy: Prospects for Treating Head and Neck Cancers With Checkpoint Inhibitor Antibodies

Ward, F. J., Dahal, L. N. & Abu-Eid, R., 24 Sep 2018, In : Frontiers in Immunology. 9, 12 p., 2182.

Research output: Contribution to journalReview article

Open Access
File
Head and Neck Neoplasms
Immunotherapy
Antibodies
Neoplasms
Therapeutics
5 Citations (Scopus)
5 Downloads (Pure)

Proteomics for early detection of colorectal cancer: recent updates

Alnabulsi, A. & Murray, G. I., 2018, In : Expert Review of Proteomics. 15, 1, p. 55-63 9 p.

Research output: Contribution to journalReview article

Open Access
File
Biomarkers
Early Detection of Cancer
Proteomics
Colorectal Neoplasms
Survival Rate
5 Citations (Scopus)

Regulation and trafficking of muscarinic acetylcholine receptors

Zenko, D. & Hislop, J. N., 30 Jul 2018, In : Neuropharmacology. 136, Part C, p. 374-382 9 p.

Research output: Contribution to journalReview article

Muscarinic Receptors
Physiological Phenomena
Signal Transduction
Therapeutics
41 Citations (Scopus)

Review article: the gut microbiome in inflammatory bowel disease-avenues for microbial management

McIlroy, J., Ianiro, G., Mukhopadhya, I., Hansen, R. & Hold, G. L., 30 Jan 2018, In : Alimentary Pharmacology & Therapeutics. 47, 1, p. 26-42 17 p.

Research output: Contribution to journalReview article

Inflammatory Bowel Diseases
Microbiota
Crohn Disease
Therapeutics
Gastrointestinal Microbiome
2 Citations (Scopus)
3 Downloads (Pure)

Taking control: Hijacking of Rab GTPases by intracellular bacterial pathogens

Spano, S. & Galán, J. E., 2018, In : Small GTPases. 9, 1-2, p. 182-191 10 p.

Research output: Contribution to journalReview article

Open Access
File
rab GTP-Binding Proteins
Pathogens
GTP Phosphohydrolases
Legionella pneumophila
Intracellular Membranes
9 Citations (Scopus)
6 Downloads (Pure)

Tissue control of androgen action: The ups and downs of androgen receptor expression

Hunter, I., Hay, C. W., Esswein, B., Watt, K. & McEwan, I. J., 15 Apr 2018, In : Molecular and Cellular Endocrinology. 465, p. 27-35 9 p.

Research output: Contribution to journalReview article

Open Access
File
Androgen Receptors
Androgens
Genes
Tissue
Testosterone
2017
2 Citations (Scopus)
3 Downloads (Pure)

Advances in the development of improved animal-free models for use in breast cancer biomedical research

Roberts, S. & Speirs, V., Aug 2017, In : Biophysical Journal. 9, 4, p. 321-327 7 p.

Research output: Contribution to journalReview article

Open Access
File
Biomedical Research
Animal Models
Breast Neoplasms
Animal Diseases
Translational Medical Research
4 Citations (Scopus)
9 Downloads (Pure)

Alzheimer's disease pathology and the unfolded protein response: Prospective pathways and therapeutic targets

Koss, D. J. & Platt, B., 1 Apr 2017, In : Behavioural Pharmacology. 28, 2 and 3 - Special Issue, p. 161-178 18 p.

Research output: Contribution to journalReview article

Open Access
File
Unfolded Protein Response
Alzheimer Disease
Endoplasmic Reticulum
Pathology
Therapeutics
29 Citations (Scopus)
4 Downloads (Pure)

Immunotherapeutic approaches to treatment of fungal diseases

Armstrong-James, D., Brown, G. D., Netea, M. G., Zelante, T., Gresnigt, M. S., van de Veerdonk, F. L. & Levitz, S. M., Dec 2017, In : Lancet Infectious Diseases. 17, 12, p. 393-402 10 p.

Research output: Contribution to journalReview article

Open Access
File
Mycoses
Pharmaceutical Preparations
Active Immunotherapy
Pandemics
Therapeutics
22 Citations (Scopus)
5 Downloads (Pure)

In vivo models in breast cancer research: progress, challenges and future directions

Holen, I., Speirs, V., Morrissey, B. & Blyth, K., 1 Apr 2017, In : Disease Models & Mechanisms. 10, 4, p. 359-371 13 p.

Research output: Contribution to journalReview article

Open Access
File
Breast Neoplasms
Research
Drug Resistance
Heterografts
Immune System
132 Citations (Scopus)

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines

Antal, A., Alekseichuk, I., Bikson, M., Brockmöller, J., Brunoni, A. R., Chen, R., Cohen, L. G., Dowthwaite, G., Ellrich, J., Flöel, A., Fregni, F., George, M. S., Hamilton, R., Haueisen, J., Herrmann, C. S., Hummel, F. C., Lefaucheur, J. P., Liebetanz, D., Loo, C. K., McCaig, C. D. & 21 others, Miniussi, C., Miranda, P. C., Moliadze, V., Nitsche, M. A., Nowak, R., Padberg, F., Pascual-Leone, A., Poppendieck, W., Priori, A., Rossi, S., Rossini, P. M., Rothwell, J., Rueger, M. A., Ruffini, G., Schellhorn, K., Siebner, H. R., Ugawa, Y., Wexler, A., Ziemann, U., Hallett, M. & Paulus, W., Sep 2017, In : Clinical Neurophysiology. 128, 9, p. 1774-1809 36 p.

Research output: Contribution to journalReview article

Electric Stimulation
Guidelines
Safety
Transcranial Direct Current Stimulation
Skin
18 Citations (Scopus)

Screening of colorectal cancer: present and future

Maida, M., Macaluso, F. S., Ianiro, G., Mangiola, F., Sinagra, E., Hold, G., Maida, C., Cammarota, G., Gasbarrini, A. & Scarpulla, G., 2017, In : Expert Review of Anticancer Therapy. 17, 12, p. 1131-1146 16 p.

Research output: Contribution to journalReview article

Colorectal Neoplasms
Early Detection of Cancer
Colonoscopy
Cause of Death
Neoplasms
8 Citations (Scopus)

The potential role of adult stem cells in the management of the rheumatic diseases

Franceschetti, T. & De Bari, C., Jul 2017, In : Therapeutic advances in musculoskeletal disease. 9, 7, p. 165-179 15 p.

Research output: Contribution to journalReview article

Adult Stem Cells
Rheumatic Diseases
Musculoskeletal Diseases
Salvage Therapy
Systemic Scleroderma
2016
43 Citations (Scopus)

Drug resistance in eukaryotic microorganisms

Fairlamb, A. H., Gow, N. A. R., Matthews, K. R. & Waters, A. P., Jul 2016, In : Nature Microbiology. 1, 14 p., 16092.

Research output: Contribution to journalReview article

Drug Resistance
Therapeutics
Drug Therapy
Microbial Drug Resistance
Epidemiology
11 Citations (Scopus)
6 Downloads (Pure)

Integrative analysis of the colorectal cancer proteome: potential clinical impact

Alnabulsi, A. & Murray, G. I., Oct 2016, In : Expert Review of Proteomics. 13, 10, p. 917-927 11 p.

Research output: Contribution to journalReview article

Open Access
File
134 Citations (Scopus)
9 Downloads (Pure)

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

Šimić, G., Babić Leko, M., Wray, S., Harrington, C., Delalle, I., Jovanov-Milošević, N., Bažadona, D., Buée, L., de Silva, R., Giovanni, G. D., Wischik, C. & Hof, P. R., Mar 2016, In : Biomolecules. 6, 1, 27 p., 6.

Research output: Contribution to journalReview article

Open Access
File
Tauopathies
tau Proteins
Alzheimer Disease
Agglomeration
Pathology
2015
14 Citations (Scopus)

Androgen receptor and antiandrogen therapy in male breast cancer

Di Lauro, L., Barba, M., Pizzuti, L., Vici, P., Sergi, D., Di Benedetto, A., Mottolese, M., Speirs, V., Santini, D., De Maria, R. & Maugeri-Saccà, M., 1 Nov 2015, In : Cancer Letters. 368, 1, p. 20-25 6 p.

Research output: Contribution to journalReview article

Male Breast Neoplasms
Androgen Antagonists
Androgen Receptors
Estrogen Receptor Modulators
Therapeutics

'Stejneger's Stonechat' in Dorset: New to Britain

Cade, M. & Collinson, J. M., 1 Jul 2015, In : British Birds. 108, 7, p. 423-427 5 p.

Research output: Contribution to journalReview article

United Kingdom
Texel
birds
DNA
Western European region
2013
204 Citations (Scopus)
4 Downloads (Pure)

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Eccles, S. A., Aboagye, E. O., Ali, S., Anderson, A. S., Armes, J., Berditchevski, F., Blaydes, J. P., Brennan, K., Brown, N. J., Bryant, H. E., Bundred, N. J., Burchell, J. M., Campbell, A. M., Carroll, J. S., Clarke, R. B., Coles, C. E., Cook, G. J. R., Cox, A., Curtin, N. J., Dekker, L. V. & 67 others, Silva, I. D. S., Duffy, S. W., Easton, D. F., Eccles, D. M., Edwards, D. R., Edwards, J., Evans, D., Fenlon, D. F., Flanagan, J. M., Foster, C., Gallagher, W. M., Garcia-Closas, M., Gee, J. M. W., Gescher, A. J., Goh, V., Groves, A. M., Harvey, A. J., Harvie, M., Hennessy, B. T., Hiscox, S., Holen, I., Howell, S. J., Howell, A., Hubbard, G., Hulbert-Williams, N., Hunter, M. S., Jasani, B., Jones, L. J., Key, T. J., Kirwan, C. C., Kong, A., Kunkler, I. H., Langdon, S. P., Leach, M. O., Mann, D. J., Marshall, J. F., Martin, L., Martin, S. G., Macdougall, J. E., Miles, D. W., Miller, W. R., Morris, J. R., Moss, S. M., Mullan, P., Natrajan, R., O'Connor, J. P. B., O'Connor, R., Palmieri, C., Pharoah, P. D. P., Rakha, E. A., Reed, E., Robinson, S. P., Sahai, E., Saxton, J. M., Schmid, P., Smalley, M. J., Speirs, V., Stein, R., Stingl, J., Streuli, C. H., Tutt, A. N. J., Velikova, G., Walker, R. A., Watson, C. J., Williams, K. J., Young, L. S. & Thompson, A. M., 1 Oct 2013, In : Breast Cancer Research. 15, 5, 37 p., R92.

Research output: Contribution to journalReview article

Open Access
File
Translational Medical Research
Breast Neoplasms
Biomarkers
Epigenomics
Breast
29 Citations (Scopus)

Insulin-like growth factor — Oestradiol crosstalk and mammary gland tumourigenesis

Hawsawi, Y., El-Gendy, R., Twelves, C., Speirs, V. & Beattie, J., Dec 2013, In : Biochimica et Biophysica Acta. 1836, 2, p. 345-353 9 p.

Research output: Contribution to journalReview article

Somatomedins
Human Mammary Glands
Estradiol
Intercellular Signaling Peptides and Proteins
Estrogens
21 Citations (Scopus)

The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example

Pinder, S. E., Brown, J. P., Gillett, C., Purdie, C. A., Speirs, V., Thompson, A. M., Shaaban, A. M. & Translational Subgroup of the NCRI Breast Clinical Studies Group, Mar 2013, In : Journal of Clinical Pathology. 66, 3, p. 169-177 9 p.

Research output: Contribution to journalReview article

Tissue Array Analysis
Translational Medical Research
Checklist
Clinical Trials
Breast Neoplasms
2012
19 Citations (Scopus)

Alzheimer disease as a vascular disorder: where do mitochondria fit?

Correia, S. C., Santos, R. X., Cardoso, S., Carvalho, C., Candeias, E., Duarte, A. I., Plácido, A. I., Santos, M. S. & Moreira, P. I., Nov 2012, In : Experimental Gerontology. 47, 11, p. 878-886 9 p.

Research output: Contribution to journalReview article

Mitochondria
Blood Vessels
Alzheimer Disease
Organelles
Disease Progression
102 Citations (Scopus)

Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation

Correia, S. C., Santos, R. X., Carvalho, C., Cardoso, S., Candeias, E., Santos, M. S., Oliveira, C. R. & Moreira, P. I., 2 Mar 2012, In : Brain Research. 1441, p. 64-78 15 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Mitochondria
Insulin
Amyloidogenic Proteins
Glucose
39 Citations (Scopus)

Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases

Correia, S. C., Santos, R. X., Perry, G., Zhu, X., Moreira, P. I. & Smith, M. A., 2012, In : Advances in Experimental Medicine and Biology. 724, p. 205-221 17 p.

Research output: Contribution to journalReview article

Mitochondria
Huntington Disease
Parkinson Disease
Alzheimer Disease
Neurons
28 Citations (Scopus)

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

Santos, R. X., Correia, S. C., Zhu, X., Lee, H-G., Petersen, R. B., Nunomura, A., Smith, M. A., Perry, G. & Moreira, P. I., 2012, In : FREE RADICAL RESEARCH. 46, 4, p. 565-576 12 p.

Research output: Contribution to journalReview article

Mitochondrial DNA
Alzheimer Disease
DNA Repair
Oxidation
Oxidative Stress
7 Citations (Scopus)

Prospective guidance in a free-swimming cell

Delafield-Butt, J. T., Pepping, G. J., McCaig, C. D. & Lee, D. N., Jul 2012, In : Biological Cybernetics. 106, 4-5, p. 283-293 11 p.

Research output: Contribution to journalReview article

Electric fields
Paramecium
Urodela
Systems Theory
Mammals
38 Citations (Scopus)

The impairment of insulin signaling in Alzheimer's disease

Candeias, E., Duarte, A. I., Carvalho, C., Correia, S. C., Cardoso, S., Santos, R. X., Plácido, A. I., Perry, G. & Moreira, P. I., Dec 2012, In : IUBMB life. 64, 12, p. 951-957 7 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Insulin
Brain Diseases
Neurodegenerative Diseases
Central Nervous System
8 Citations (Scopus)

What the eye doesn't see: The prevalence of fraud in ornithology

Harrop, A. H. J., Collinson, J. M. & Melling, T., 1 May 2012, In : British Birds. 105, 5, p. 236-257 22 p.

Research output: Contribution to journalReview article

fraud
ornithology
eyes
United Kingdom
2011
622 Citations (Scopus)
4 Downloads (Pure)

Choosing the right cell line for breast cancer research

Holliday, D. L. & Speirs, V., 12 Aug 2011, In : Breast Cancer Research. 13, 215.

Research output: Contribution to journalReview article

Open Access
File
Breast Neoplasms
Cell Line
Research
Gene Expression Profiling
Estrogen Receptors
61 Citations (Scopus)

Male breast carcinoma: increased awareness needed

White, J., Kearins, O., Dodwell, D., Horgan, K., Hanby, A. M. & Speirs, V., 29 Sep 2011, In : Breast Cancer Research. 13, 219.

Research output: Contribution to journalReview article

Open Access
Male Breast Neoplasms
Prolactin Receptors
Paintings
Aromatase Inhibitors
Incidence
2010
9 Citations (Scopus)

Conditions of the male breast: Gynaecomastia and male breast cancer (Review)

Alali, L., Honarpisheh, H., Shaaban, A. & Speirs, V., Jan 2010, In : Molecular Medicine Reports. 3, 1, p. 21-26 6 p.

Research output: Contribution to journalReview article

Male Breast Neoplasms
Breast Diseases
Breast
Databases
Incidence
2009
16 Citations (Scopus)

Sleep and hippocampus: Do we search for the right things?

Brankačk, J., Platt, B. & Riedel, G., 1 Aug 2009, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33, 5, p. 806-812 7 p.

Research output: Contribution to journalReview article

Hippocampus
Sleep
Learning
Body Temperature Regulation
Brain
2008
64 Citations (Scopus)

Small is beautiful: microRNAs and breast cancer-where are we now?

Verghese, E. T., Hanby, A. M., Speirs, V. & Hughes, T. A., Jul 2008, In : The Journal of pathology. 215, 3, p. 214-21 8 p.

Research output: Contribution to journalReview article

MicroRNAs
Breast Neoplasms
Biological Phenomena
Estrogen Receptor alpha
RNA Stability
18 Citations (Scopus)

The potential role of ER beta isoforms in the clinical management of breast cancer

Green, C. A., Peter, M. B., Speirs, V. & Shaaban, A. M., Oct 2008, In : Histopathology. 53, 4, p. 374-80 7 p.

Research output: Contribution to journalReview article

Protein Isoforms
Breast Neoplasms
Estrogen Receptor beta
Exons
Research
2007
45 Citations (Scopus)

New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast

Speirs, V. & Walker, R. A., Apr 2007, In : The Journal of pathology. 211, 5, p. 499-506 8 p.

Research output: Contribution to journalReview article

Estrogen Receptor beta
Estrogen Receptors
Breast
Estrogen Receptor alpha
Biological Factors
2006
4 Citations (Scopus)

Clinicians' guide to microarrays

Maraqa, L., Donnellan, C. F., Peter, M. B. & Speirs, V., Dec 2006, In : European Journal of Surgical Oncology. 15, 4, p. 205-10 6 p.

Research output: Contribution to journalReview article

Neoplasms
Therapeutics
Breast Neoplasms
Technology
376 Citations (Scopus)

Molecular mechanisms of action of bisphosphonates: current status

Roelofs, A. J., Thompson, K., Gordon, S. A. & Rogers, M. J., 2006, In : Clinical Cancer Research. 12, 20 PT 2, p. 6222S-6230S 9 p.

Research output: Contribution to journalReview article

45 Citations (Scopus)

Properties and characteristics of the dyes injected to assist axillary sentinel node localization in breast surgery

Masannat, Y., Shenoy, H., Speirs, V., Hanby, A. & Horgan, K., May 2006, In : European Journal of Surgical Oncology. 32, 4, p. 381-4 4 p.

Research output: Contribution to journalReview article

Breast
Coloring Agents
Sentinel Lymph Node Biopsy
Breast Neoplasms
Safety
2005
6 Citations (Scopus)

Angiogenesis in breast cancer: How should we measure this? (Review)

Pollitt, M. J. K., Hanby, A. M., Horgan, K., Murphy, C. E., Jones, P. F. & Speirs, V., May 2005, In : Oncology Reports. 13, 5, p. 931-936 6 p.

Research output: Contribution to journalReview article

Breast Neoplasms
Neoplasms