Medicine, Medical Sciences & Nutrition

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Research Output 1970 2019

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2019

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., 10 Apr 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Open Access
Retinoic Acid Receptors
AMPA Receptors
Glutamate Receptors
Tretinoin
Ligands
1 Downloads (Pure)

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 3 Apr 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

Research output: Contribution to journalArticle

Open Access
File
Luminescent Proteins
Optical Imaging
Fungi
Fungal Proteins
Mycoses

A case-note review of continued pregnancies found to be at a high risk of Huntington’s disease: considerations for clinical practice

on behalf of the UK Huntington’s Disease Predictive Testing Consortium, Wadrup, F., Holden, S., MacLeod, R., Miedzybrodzka, Z., Németh, A. H., Owens, S., Pasalodos, S., Quarrell, O. & Clarke, A. J., 19 Mar 2019, In : European Journal of Human Genetics.

Research output: Contribution to journalArticle

Huntington Disease
Pregnancy
High-Risk Pregnancy
Prenatal Care
Confidentiality

Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: Protocol for a randomised patient-focused pilot trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma

Murchie, P., Masthoff, J., Walter, F. M., Rahman, K., Allan, J. L., Burrows, N., Proby, C., Lee, A. J., Johnston, M., Durrani, A., Depasquale, I., Brant, B., Neilson, A., Meredith, F., Treweek, S. P., Hall, S. J. & McDonald, A. M., 18 May 2019, (Accepted/In press) In : Trials.

Research output: Contribution to journalArticle

Aftercare
Melanoma
Self-Examination
Neoplasms
Skin

A comparison of professional and private time preferences of General Practitioners

Irvine, A., Van der Pol, M. & Phimister, E., 1 Feb 2019, In : Social Science & Medicine. 222, p. 256-264 9 p.

Research output: Contribution to journalArticle

general practitioner
General Practitioners
Patient Preference
Health
Likelihood Functions

A conceptual framework for patient-directed knowledge tools to support patient-centred care: Results from an evidence-informed consensus meeting

Dreesens, D., Stiggelbout, A., Agoritsas, T., Elwyn, G., Flottorp, S., Grimshaw, J., Kremer, L., Santesso, N., Stacey, D., Treweek, S., Armstrong, M., Gagliardi, A., Hill, S., Légaré, F., Ryan, R., Vandvik, P. & van der Weijden, T., 4 May 2019, (Accepted/In press) In : Patient Education and Counseling.

Research output: Contribution to journalArticle

Consensus
Self Care
Decision Making

Activity energy expenditure is an independent predictor of energy intake in humans

Hopkins, M., Duarte, C., Beaulieu, K., Finlayson, G., Gibbons, C., Johnstone, A., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 18 Jan 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Energy Intake
Energy Metabolism
Basal Metabolism
Body Composition
Diet Records

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Glutathione
Zinc

Addressing medication errors in an adult oncology department in Saudi Arabia: A qualitative study

Alharbi, W., Cleland, J. & Morrison, Z., 19 Mar 2019, In : Saudi Pharmaceutical Journal.

Research output: Contribution to journalArticle

Open Access
Medication Errors
Saudi Arabia
Communication
Delivery of Health Care
Education
Dental Schools
Crowns
Tongue
Tooth
Students

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

Vickers, M. A., Jan 2019, In : Cells. 8, 1, doi: 10.3390/cells8010047.

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cell Transplantation
Virus Diseases
Cell- and Tissue-Based Therapy
Viruses
T-Lymphocytes
1 Citation (Scopus)
2 Downloads (Pure)

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
File
Age of Onset
Walking
Hip
Walkers
Femur Neck

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C-D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Muller, B. & Connolly, B., 5 Apr 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression

A literature review of the predictive validity of European dental school selection methods

Cunningham, C., Patterson, F. & Cleland, J., May 2019, In : European Journal of Dental Education. 23, 2, p. 73-87 15 p.

Research output: Contribution to journalArticle

Dental Schools
Aptitude
school
Dentistry
Research
2 Downloads (Pure)

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler, P., 14 Feb 2019, In : PLoS Biology. 17, 2, e3000002.

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens

AMEE guide no. 123 - How to read studies of educational costs

Maloney, S., Cook, D. A., Golub, R., Foo, J., Cleland, J., Rivers, G., Tolsgaard, M. G., Evans, D., Abdalla, M. E. & Walsh, K., 2019, In : Medical Teacher. p. 1-8 8 p.

Research output: Contribution to journalArticle

decision making
costs
opportunity costs
economics
decision maker

A model for spatio-temporal injury surveillance: implications for the evolution of a trauma system

Jansen, J. O., Emerson, P., Morrison, J. J. & Cornulier, T., Feb 2019, In : The journal of trauma and acute care surgery. 86, 2, p. 289-298 10 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Scotland
Hebrides
Islands
Population
1 Downloads (Pure)
Open Access
File
Antigen Receptors
Transgenic Mice
Autoimmune Diseases
Arthritis
Tumor Necrosis Factor-alpha
3 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 8 May 2019, (Accepted/In press) In : Frontiers in Microbiology.

Research output: Contribution to journalArticle

Open Access
Mycoses
Skin
Infection
Microscopy
Animal Models
Streptomyces griseus
Lactalbumin
Pronase
lactalbumin
enzymatic treatment
1 Downloads (Pure)

Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting

Ablett, A. D., Browning, A., Quan, V., Tay, H. S., McCormack, C., Carter, B., Hewitt, J., Myint, P. K. & Older Persons Surgical Outcomes Collaboration (OPSOC), Apr 2019, In : Asian Journal of Surgery. 42, 4, p. 527-534 8 p.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Emergencies
Patients' Rooms
Odds Ratio
Length of Stay

An update on Staphylococcus aureus infective endocarditis from the International Society of Antimicrobial Chemotherapy (ISAC)

Saeed, K., Bal, A., Gould, I., David, M. Z., Dryden, M., Giannitsioti, E., Hijazi, K., Meisner, J. A., Esposito, S., Scaglione, F., Tattevin, P. & Voss, A., Jan 2019, In : International Journal of Antimicrobial Agents. 53, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Endocarditis
Staphylococcus aureus
Drug Therapy
Tricuspid Valve
Coagulase

A pilot study to improve sugar and water consumption in Maltese school children

Copperstone, C., McNeill, G., Aucott, L. & Jackson, D. M., 15 Feb 2019, In : International Journal of Adolescent Medicine and Health.

Research output: Contribution to journalArticle

Drinking
Pediatric Obesity
Energy Intake
Drinking Water
Parents
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care
1 Citation (Scopus)
2 Downloads (Pure)

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., D'Santos, C., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., Mills, I. G., Carroll, J. S. & 5 othersTilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 2019, In : Oncogene. 38, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome

A retino-retinal projection guided by Unc5c emerged in species with retinal waves

Murcia-Belmonte, V., Coca, Y., Vegar, C., Negueruela, S., de Juan, C., Valiño, A. J., Sala, S., DaSilva, R., Kania, A., Borrell, V., Martinez, L. M., Erskine, L. & Herrera, E., Apr 2019, In : Current Biology. 29, 7, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

Open Access
File
axons
Axons
retina
Diencephalon
Artifacts
Dietetics
Prostatic Neoplasms
Randomized Controlled Trials
Exercise
Weights and Measures

Association between hours worked in paid employment and diet quality, frequency of eating out and having takeaways in the UK

Sam, L., Craig, T., Macdiarmid, J. & Horgan, G., 17 May 2019, (Accepted/In press) In : Public Health Nutrition.

Research output: Contribution to journalArticle

Open Access
File
Eating
Food
Linear Models
Diet Surveys
Logistic Models
Ankylosing Spondylitis
Biological Products
Smoking
Fatigue
Sleep

A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements

Huang, I., Mak, D., Cheung, P., Abraham, M., Clemens, T. & Turner, S., 8 Apr 2019, In : Environmental Research. 173, p. 528-538 11 p.

Research output: Contribution to journalArticle

Maternal Exposure
smoking
pregnancy
Nitrogen Dioxide
Smoking

Atrial fibrillation case finding in over 65 s with cardiovascular risk factors – Results of initial Scottish clinical experience

Grubb, N. R., Elder, D., Broadhurst, P., Reoch, A., Tassie, E. & Neilson, A., 1 Aug 2019, In : International Journal of Cardiology. 288, p. 94-99 6 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Electrocardiography
Primary Health Care
Stroke
Scotland

AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS)

MacFarlane, G. J., Pathan, E., Siebert, S., Packham, J., Gaffney, K., Choy, E. H., Sengupta, R., Atzeni, F., Martin, K. R., Jones, G. T. & Dean, L., 25 Apr 2019, (Accepted/In press) In : BMC Rheumatology.

Research output: Contribution to journalArticle

1 Downloads (Pure)

Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn's Disease

Delday, M., Mulder, I., Logan, E. T. & Grant, G., 1 Jan 2019, In : Inflammatory Bowel Diseases. 25, 1, p. 85-96 11 p.

Research output: Contribution to journalArticle

Open Access
File
Crohn Disease
Inflammatory Bowel Diseases
Dextran Sulfate
Inflammation
Weight Loss
Molecular Pathology
National Cancer Institute (U.S.)
Clinical Trials
Pathology
Research

Batrachochytrium salamandrivorans

Farrer, R. A., 22 May 2019, In : Trends in Microbiology. 2 p.

Research output: Contribution to journalArticle

Behavioural intervention for weight loss maintenance versus standard weight advice in adults with obesity: A randomised controlled trial in the UK (NULevel Trial)

Sniehotta, F. F., Evans, E. H., Sainsbury, K., Adamson, A., Batterham, A., Becker, F., Brown, H., Dombrowski, S. U., Jackson, D., Howell, D., Ladha, K., McColl, E., Olivier, P., Rothman, A. J., Steele, A., Vale, L., Vieira, R., White, M., Wright, P. & Araujo-Soares, V., 7 May 2019, In : PLoS Medicine. 16, 5, 18 p., e1002793.

Research output: Contribution to journalArticle

Open Access
File
Weight Loss
Randomized Controlled Trials
Obesity
Maintenance
Weights and Measures
2 Downloads (Pure)
Open Access
File
Pain Management
Population
Pain
Mass Media
Fear
1 Citation (Scopus)

Benefits of Empiric Nutritional and Medical Therapy for Semen Parameters and Pregnancy and Live Birth Rates in Couples with Idiopathic Infertility: A Systematic Review and Meta-analysis

Omar, M. I., Pal, R. P., Kelly, B. D., Bruins, H. M., Yuan, Y., Diemer, T., Krausz, C., Tournaye, H., Kopa, Z., Jungwirth, A. & Minhas, S., Apr 2019, In : European Urology. 75, 4, p. 615-625 11 p.

Research output: Contribution to journalArticle

Pregnancy Rate
Semen
Infertility
coenzyme Q10
Kallikreins

Beyond elections: perceptions of democracy in four Arab countries

Teti, A., Abbott, P. & Cavatorta, F., 2019, In : Democratization. 26, 4, p. 645-665 21 p.

Research output: Contribution to journalArticle

Arab countries
election
democracy
political right
Tunisia
4 Citations (Scopus)
3 Downloads (Pure)

Biological and psychological mediators of the relationships between fat mass, fat-free mass and energy intake

Hopkins, M., Finlayson, G., Duarte, C., Gibbons, C., Johnstone, A. M., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 2019, In : International Journal of Obesity. 43, p. 233-242 42 p.

Research output: Contribution to journalArticle

Open Access
File
Energy Intake
Fats
Psychology
Basal Metabolism
Leptin

Biological Concepts for the Control of Aquatic Zoosporic Diseases

Frenken, T., Agha, R., Schmeller, D. S., van West, P. & Wolinska, J., 7 May 2019, In : Trends in Parasitology. 12 p.

Research output: Contribution to journalArticle

Plankton
Aquaculture
Biodiversity
Amphibians
Ecology

Blood pressure differences between home monitoring and daytime ambulatory values and their reproducibility in treated hypertensive stroke and TIA patients

Davison, W. J., Myint, P. K., Clark, A. B. & Potter, J. F., Jan 2019, In : American Heart Journal. 207, p. 58-65 8 p.

Research output: Contribution to journalArticle

Ambulatory Monitoring
Stroke
Blood Pressure
Ambulatory Blood Pressure Monitoring
Cerebrovascular Disorders

Bridging the cultural divide? Exploring UK school pupils’ perceptions of medicine

Alexander, K., Cleland, J. & Nicholson, S., 14 Feb 2019, In : Medical Education. 53, 6, p. 571-583 13 p.

Research output: Contribution to journalArticle

pupil
medicine
school
career
sociocultural factors
1 Downloads (Pure)

CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation

Ashraf, S., Bell, S., O'Leary, C., Canning, P., Micu, I., Fernandez, J. A., O'Hare, M., Barabas, P., McCauley, H., Brazil, D. P., Stitt, A. W., McGeown, J. G. & Curtis, T. M., 21 Mar 2019, In : JCI Insight. 4, 6, e122442.

Research output: Contribution to journalArticle

Open Access
File
Retinal Neovascularization
Choroidal Neovascularization
Calcium-Calmodulin-Dependent Protein Kinases
Pathologic Neovascularization
Intercellular Signaling Peptides and Proteins

Cancer and motor neuron disease—causal or coincidental? Two contrasting cases

Goodfellow, J., Gorrie, G., Leach, V., Patel, S. & Mackay, G., 6 Mar 2019, In : Neurological Sciences. p. 1-3 3 p.

Research output: Contribution to journalArticle

Motor Neurons
Upper Extremity
Fasciculation
Lower Extremity
Neoplasms

Candida albicans: Microbe of the month

Wilson, D., Feb 2019, In : Trends in Microbiology. 27, 2, p. 188-189 2 p.

Research output: Contribution to journalArticle

Can we understand and improve poorer cancer survival in rural-dwellers?

Murchie, P., Adam, R., Wood, R. & Fielding, S., 14 May 2019, In : BJGP Open. 4 p.

Research output: Contribution to journalArticle

Open Access