Medicine, Medical Sciences & Nutrition

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Research Output 1970 2019

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Article
2019
2 Citations (Scopus)

27 years of prenatal diagnosis for Huntington disease in the United Kingdom

Piña-Aguilar, R. E., Simpson, S. A., Alshatti, A., Clarke, A., Craufurd, D., Dorkins, H., Doye, K., Lahiri, N., Lashwood, A., Lynch, C., Miller, C., Morton, S., O’Driscoll, M., Quarrell, O. W., Rae, D., Strong, M., Tomlinson, C., Turnpenny, P., Miedzybrodzka, Z. & UK HD Predictive Testing Consortium, Jul 2019, In : Genetics in Medicine. 21, p. 1639–1643 5 p.

Research output: Contribution to journalArticle

Preimplantation Diagnosis
Huntington Disease
Prenatal Diagnosis
United Kingdom
Neurodegenerative Diseases

ABC Transporter Genes Show Upregulated Expression in Drug Resistant Clinical Isolates of Candida auris: a Genome-Wide Characterization of ATP-Binding Cassette (ABC) Transporter Genes

Wasi, M., Khandelwal, N. K., Moorhouse, A. J., Nair, R., Vishwakarma, P., Ruiz, G. B., Ross, Z. K., Lorenz, A., Rudramurthy, S. M., Chakrabarti, A., Lynn, A. M., Mondal, A. K., Gow, N. A. R. & Prasad, R., Jul 2019, In : Frontiers in Microbiology. 10, 16 p., 1445.

Research output: Contribution to journalArticle

Open Access
File
ATP-Binding Cassette Transporters
Candida
Genome
Pharmaceutical Preparations
Genes

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., 10 Apr 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Open Access
Retinoic Acid Receptors
AMPA Receptors
Glutamate Receptors
Tretinoin
Ligands
5 Downloads (Pure)

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 1 Jun 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

Research output: Contribution to journalArticle

Open Access
File
Luminescent Proteins
Optical Imaging
Fungi
Fungal Proteins
Mycoses

A case-note review of continued pregnancies found to be at a high risk of Huntington’s disease: considerations for clinical practice

Wadrup, F., Holden, S., MacLeod, R., Miedzybrodzka, Z., Németh, A. H., Owens, S., Pasalodos, S., Quarrell, O., Clarke, A. J. & on behalf of the UK Huntington’s Disease Predictive Testing Consortium, 19 Mar 2019, In : European Journal of Human Genetics. 27, p. 1215-1224 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Prenatal Diagnosis
Pregnancy
High-Risk Pregnancy
Prenatal Care
1 Downloads (Pure)
Open Access
File
Aftercare
Melanoma
Self-Examination
Neoplasms
Skin

A comparison of professional and private time preferences of General Practitioners

Irvine, A., Van der Pol, M. & Phimister, E., 1 Feb 2019, In : Social Science & Medicine. 222, p. 256-264 9 p.

Research output: Contribution to journalArticle

general practitioner
General Practitioners
Patient Preference
Health
Likelihood Functions

A conceptual framework for patient-directed knowledge tools to support patient-centred care: Results from an evidence-informed consensus meeting

Dreesens, D., Stiggelbout, A., Agoritsas, T., Elwyn, G., Flottorp, S., Grimshaw, J., Kremer, L., Santesso, N., Stacey, D., Treweek, S., Armstrong, M., Gagliardi, A., Hill, S., Légaré, F., Ryan, R., Vandvik, P. & van der Weijden, T., 4 May 2019, In : Patient Education and Counseling.

Research output: Contribution to journalArticle

Patient-Centered Care
Consensus
Self Care
Decision Making
1 Citation (Scopus)

Activity energy expenditure is an independent predictor of energy intake in humans

Hopkins, M., Duarte, C., Beaulieu, K., Finlayson, G., Gibbons, C., Johnstone, A., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 1 Jul 2019, In : International Journal of Obesity. 43, 7, p. 1466–1474 9 p.

Research output: Contribution to journalArticle

Open Access
File
Energy Intake
Energy Metabolism
Basal Metabolism
Body Composition
Diet Records

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Glutathione
Zinc

Addressing medication errors in an adult oncology department in Saudi Arabia: A qualitative study

Alharbi, W., Cleland, J. & Morrison, Z., Jul 2019, In : Saudi Pharmaceutical Journal. 27, 5, p. 650-654 5 p.

Research output: Contribution to journalArticle

Open Access
File
Medication Errors
Saudi Arabia
Communication
Delivery of Health Care
Education
Dental Schools
Crowns
Tongue
Tooth
Students

Advancing human health risk assessment

Lanzoni, A., Castoldi, A. F., Kass, G. E. N., Terron, A., De Seze, G., Bal-Price, A., Bois, F. Y., Delclos, K. B., Doerge, D. R., Fritsche, E., Halldorsson, T., Kolossa-Gehring, M., Hougaard Bennekou, S., Koning, F., Lampen, A., Leist, M., Mantus, E., Rousselle, C., Siegrist, M., Steinberg, P. & 7 othersTritscher, A., Van de Water, B., Vineis, P., Walker, N., Wallace, H., Whelan, M. & Younes, M., Jul 2019, In : EFSA Journal. 17, S1, 21 p., e170712.

Research output: Contribution to journalArticle

Open Access
File
risk assessment
human health
Health
risk assessors
risk managers
1 Citation (Scopus)
7 Downloads (Pure)

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
File
Age of Onset
Walking
Hip
Walkers
Femur Neck
4 Downloads (Pure)

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C-D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity
4 Downloads (Pure)

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Muller, B. & Connolly, B., 5 Apr 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression

A literature review of the predictive validity of European dental school selection methods

Cunningham, C., Patterson, F. & Cleland, J., May 2019, In : European Journal of Dental Education. 23, 2, p. 73-87 15 p.

Research output: Contribution to journalArticle

Dental Schools
Aptitude
school
Dentistry
Research
3 Citations (Scopus)
7 Downloads (Pure)

Alternative (backdoor) androgen production and masculinization in the human fetus

O'Shaughnessy, P. J., Antignac, J-P., Le Bizec, B., Morvan, M-L., Svechnikov, K., Söder, O., Savchuk, I., Monteiro, A., Soffientini, U., Johnston, Z. C., Bellingham, M., Hough, D., Walker, N., Filis, P. & Fowler, P., 14 Feb 2019, In : PLoS Biology. 17, 2, e3000002.

Research output: Contribution to journalArticle

Open Access
File
androsterone
Androsterone
masculinization
androgens
Androgens

AMEE guide no. 123 - How to read studies of educational costs

Maloney, S., Cook, D. A., Golub, R., Foo, J., Cleland, J., Rivers, G., Tolsgaard, M. G., Evans, D., Abdalla, M. E. & Walsh, K., 2019, In : Medical Teacher. 41, 5, p. 497-504 8 p.

Research output: Contribution to journalArticle

decision making
costs
opportunity costs
economics
decision maker

A model for spatio-temporal injury surveillance: implications for the evolution of a trauma system

Jansen, J. O., Emerson, P., Morrison, J. J. & Cornulier, T., Feb 2019, In : The journal of trauma and acute care surgery. 86, 2, p. 289-298 10 p.

Research output: Contribution to journalArticle

Wounds and Injuries
Scotland
Hebrides
Health Policy
Islands

An Anatomical Evaluation of a conventional Pectoralis II and a Sub-serratus Block for Breast Surgery

Robinson, H., Mishra, S., Davies, L., Craigen, F., Shahana, S. & Parson, S. H., 2019, (Submitted) In : Anesthesia and Analgesia.

Research output: Contribution to journalArticle

1 Citation (Scopus)
5 Downloads (Pure)
Open Access
File
Antigen Receptors
Transgenic Mice
Autoimmune Diseases
Arthritis
Tumor Necrosis Factor-alpha
6 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1172.

Research output: Contribution to journalArticle

Open Access
File
Mycoses
Skin
Infection
Microscopy
Animal Models
1 Downloads (Pure)

An integrated approach to processing WHO-2016 verbal autopsy data: the InterVA-5 model

Byass, P., Hussain-Alkhateeb, L., D'Ambruoso, L., Clark, S., Davies, J., Fottrell, E., Bird, J., Kabudula, C., Tollman, S., Kahn, K., Schiöler, L. & Petzold, M., 30 May 2019, In : BMC medicine . 17, 12 p., 102.

Research output: Contribution to journalArticle

Open Access
File
Autopsy
Mortality
Afghanistan
Cause of Death
Interviews
5 Downloads (Pure)

Anti-cholinergic burden and patient related clinical outcomes in an emergency general surgical setting

Ablett, A. D., Browning, A., Quan, V., Tay, H. S., McCormack, C., Carter, B., Hewitt, J., Myint, P. K. & Older Persons Surgical Outcomes Collaboration (OPSOC), Apr 2019, In : Asian Journal of Surgery. 42, 4, p. 527-534 8 p.

Research output: Contribution to journalArticle

Open Access
File
Cholinergic Antagonists
Emergencies
Patients' Rooms
Odds Ratio
Length of Stay

An update on Staphylococcus aureus infective endocarditis from the International Society of Antimicrobial Chemotherapy (ISAC)

Saeed, K., Bal, A., Gould, I., David, M. Z., Dryden, M., Giannitsioti, E., Hijazi, K., Meisner, J. A., Esposito, S., Scaglione, F., Tattevin, P. & Voss, A., Jan 2019, In : International Journal of Antimicrobial Agents. 53, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

Endocarditis
Staphylococcus aureus
Drug Therapy
Tricuspid Valve
Coagulase
4 Downloads (Pure)

Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves

Singh, A., Horsfield, M. A., Bekele, S., Greenwood, J. P., Dawson, D. K., Berry, C., Hogrefe, K., Kelly, D. J., Houston, J. G., Guntur Ramkumar, P., Uddin, A., Suzuki, T. & McCann, G. P., May 2019, In : European Radiology. 29, 5, p. 2340-2349 10 p.

Research output: Contribution to journalArticle

Open Access
File
Vascular Stiffness
Tricuspid Valve
Aortic Valve Stenosis
Mitral Valve
Pulse Wave Analysis

AP-2-dependent endocytic recycling of the chitin synthase Chs3 regulates polarized growth in Candida albicans

Knafler, H. C., Smaczynska-de Rooij, I. I., Walker, L. A., Lee, K. K., Gow, N. A. R. & Ayscougha, K. R., 19 Mar 2019, In : mBio. 10, 2, e02421-18.

Research output: Contribution to journalArticle

Open Access
Chitin Synthase
Candida albicans
Cell Wall
Growth
Hyphae

A pilot study to improve sugar and water consumption in Maltese school children

Copperstone, C., McNeill, G., Aucott, L. & Jackson, D. M., 15 Feb 2019, In : International Journal of Adolescent Medicine and Health.

Research output: Contribution to journalArticle

Drinking
Pediatric Obesity
Energy Intake
Health Promotion
Drinking Water
Opiate Substitution Treatment
Hepatitis C
Primary Health Care
Motivation
Patient Acceptance of Health Care

A qualitative study exploring the key determinants of information gathering to inform the management of over‐the‐counter (OTC) consultations in community pharmacies

Cassie, H., Duncan, E., Gibb, E., Power, A., Young, L., Newlands, R. & Watson, M. C. M., 16 Jul 2019, (Accepted/In press) In : BMJ Open.

Research output: Contribution to journalArticle

Pharmacies
Pharmacists
Referral and Consultation
Medicine
Professional Role
1 Citation (Scopus)
5 Downloads (Pure)

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., D'Santos, C., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., Mills, I. G., Carroll, J. S. & 5 othersTilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 2019, In : Oncogene. 38, 7, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome
5 Downloads (Pure)

A retino-retinal projection guided by Unc5c emerged in species with retinal waves

Murcia-Belmonte, V., Coca, Y., Vegar, C., Negueruela, S., de Juan, C., Valiño, A. J., Sala, S., DaSilva, R., Kania, A., Borrell, V., Martinez, L. M., Erskine, L. & Herrera, E., Apr 2019, In : Current Biology. 29, 7, p. 1149-1160 12 p.

Research output: Contribution to journalArticle

Open Access
File
axons
Axons
retina
Retina
Retinal Ganglion Cells
Open Access
File
Dietetics
Prostatic Neoplasms
Randomized Controlled Trials
Exercise
Diet

A simple approach to modelling the soil water budget in Scottish mineral soils

Brand, A. M., Lilly, A. & Smith, J. U., 2019, (In preparation) In : Environmental Modelling and Software.

Research output: Contribution to journalArticle

10 Downloads (Pure)

Association between hours worked in paid employment and diet quality, frequency of eating out and having takeaways in the UK

Sam, L., Craig, T., Macdiarmid, J. & Horgan, G., 17 May 2019, (Accepted/In press) In : Public Health Nutrition.

Research output: Contribution to journalArticle

Open Access
File
Eating
Diet
Food
Linear Models
Diet Surveys

Association between musculoskeletal pain with social isolation and loneliness: analysis of the English Longitudinal Study of Ageing

Smith, T. O., Dainty, J. R., Williamson, E. & Martin, K. R., 1 May 2019, In : British Journal of Pain. 13, 2, p. 82-90 9 p.

Research output: Contribution to journalArticle

Musculoskeletal Pain
Loneliness
Social Isolation
Longitudinal Studies
Health
2 Citations (Scopus)
Ankylosing Spondylitis
Biological Products
Smoking
Fatigue
Sleep

A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements

Huang, I., Mak, D., Cheung, P., Abraham, M., Clemens, T. & Turner, S., Jun 2019, In : Environmental Research. 173, p. 528-538 11 p.

Research output: Contribution to journalArticle

Maternal Exposure
smoking
pregnancy
Nitrogen Dioxide
Smoking

Atrial fibrillation case finding in over 65 s with cardiovascular risk factors – Results of initial Scottish clinical experience

Grubb, N. R., Elder, D., Broadhurst, P., Reoch, A., Tassie, E. & Neilson, A., 29 Mar 2019, In : International Journal of Cardiology. 288, p. 94-99 6 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Electrocardiography
Primary Health Care
Stroke
Scotland
Open Access
File
scanners
biomarkers
cycles
micrometers
edema
1 Downloads (Pure)

AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS)

MacFarlane, G. J., Pathan, E., Siebert, S., Packham, J., Gaffney, K., Choy, E. H., Sengupta, R., Atzeni, F., Martin, K. R., Jones, G. T. & Dean, L., 20 May 2019, In : BMC Rheumatology. 3, 19.

Research output: Contribution to journalArticle

Open Access
File
Fibromyalgia
Biological Products
Population Groups
Research
Cluster Analysis
1 Citation (Scopus)
5 Downloads (Pure)

Bacteroides thetaiotaomicron Ameliorates Colon Inflammation in Preclinical Models of Crohn's Disease

Delday, M., Mulder, I., Logan, E. T. & Grant, G., 1 Jan 2019, In : Inflammatory Bowel Diseases. 25, 1, p. 85-96 11 p.

Research output: Contribution to journalArticle

Open Access
File
Crohn Disease
Colon
Inflammatory Bowel Diseases
Dextran Sulfate
Inflammation
Molecular Pathology
National Cancer Institute (U.S.)
Clinical Trials
Pathology
Research

Batrachochytrium salamandrivorans

Farrer, R. A., 22 May 2019, In : Trends in Microbiology. 2 p.

Research output: Contribution to journalArticle

4 Downloads (Pure)

Behavioural intervention for weight loss maintenance versus standard weight advice in adults with obesity: A randomised controlled trial in the UK (NULevel Trial)

Sniehotta, F. F., Evans, E. H., Sainsbury, K., Adamson, A., Batterham, A., Becker, F., Brown, H., Dombrowski, S. U., Jackson, D., Howell, D., Ladha, K., McColl, E., Olivier, P., Rothman, A. J., Steele, A., Vale, L., Vieira, R., White, M., Wright, P. & Araujo-Soares, V., 7 May 2019, In : PLoS Medicine. 16, 5, 18 p., e1002793.

Research output: Contribution to journalArticle

Open Access
File
Weight Loss
Randomized Controlled Trials
Obesity
Maintenance
Weights and Measures
6 Downloads (Pure)
Open Access
File
Pain Management
Back Pain
Population
Pain
Mass Media