Medicine, Medical Sciences & Nutrition

  • AB25 2ZD

Research Output 1970 2019

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Patent
2017

Synthetic retinoids for use in RAR mediated conditions

Greig, I. R., McCaffery, P. J. A., Whiting, A., Valentine, R., Chisholm, D. & Khatib, T. 12 Oct 2017

Research output: Patent

Retinoids
2015

Phenothiazine compounds for treating mild cognitive impairment

Wischik, C. M., Harbaran, D. V., Riedel, G., Deiana, S., Goatman, E. A., Wischik, D. J., Murray, A. D. & Staff, R. T. 15 Dec 2015 17 Jun 2008 19 Jun 200760/945006

Research output: Patent

Cognitive Dysfunction
phenothiazine
2014

Fish Vaccine

Wawra, S., Van West, P. & Secombes, C. J. 4 Dec 2014 A61K38/16; C07K14/37; C12N15/6230 May 2013GB20130009664 20130530

Research output: Patent

vaccines
fish
nucleic acids
eukaryotic cells
plasma membrane

ISOLATION OF THERAPEUTIC TARGET SPECIFIC VNAR DOMAINS TO ICOSL

Barelle, C., Finlay, J. J. W. & Darmanin-Sheehan, A. 30 Oct 2014 C07K16/00; C07K16/18; C12N15/1323 Apr 2013US201361815043P 20130423

Research output: Patent

Antigen Receptors
Libraries
Sharks
Ligands
Squalus acanthias

Aryl-Phenyl-Sulfonamido-Cycloalkyl Compounds and Their Use

Greig, I. R., Sheridan, R. M., Fisher, R., Tozer, M. J., Clase, J. A., Smith, A., Tufnell, A. R. & van 't Hof, R. J. 19 Sep 2013

Research output: Patent

Bone and Bones
Rheumatoid Arthritis
Anistreplase
Bone Neoplasms
Psoriatic Arthritis

SINGLE DOMAIN BINDING MOLECULE

Barelle, C., Muller, M., Calabro, V., Bikker, J., Steven, J., Tchistiakova, L., Kovalenko, O. V. & Olland, A. 14 Nov 2013 C07K16/46US201313889134 20130507 ; US201261643407P 20120507

Research output: Patent

Open Access
File
Complementarity Determining Regions
Patents and inventions
Serum Albumin
Amino Acids
Molecules

USE OF PLATELET GLYCOPEPTIDE IIIA EPITOPES IN THE TREATMENT OF IMMUNE THROMBOCYTOPENIC PURPURA

Urbaniak, S., Barker, R. N. & Sukati, H. M. 27 Mar 2013 A61K38/10; A61P7/0018 Jan 2007GB0701048

Research output: Patent

Open Access
Idiopathic Thrombocytopenic Purpura
Glycopeptides
Epitopes
Blood Platelets
Autoantibodies

Bone Graft System

Gibson, I. R., Skakle, J., Annaz, B. & Conway, J. 29 Dec 2011 A61L27/46

Research output: Patent

Hydrogel
Silicon
Grafts
Bone
Durapatite

N-(ARYLALKYL)-1H-INDOLE-2-SULFONIC ACID AMIDE COMPOUNDS AND THEIR THERAPEUTIC USE AS CANNABINOID ALLOSTERIC MODULATORS

Greig, I. R., Ross, R. A., Trembleau, L. A. C., Pertwee, R. G. & Abdelrahman, M. H. 28 Feb 2011 WO2012117216

Research output: Patent

Cannabinoid Receptors
Sulfonic Acids
Cannabinoids
Therapeutic Uses
Amides

Synthesis of Bioceramic Compositions

Gibson, I. R. & Skakle, J. 27 Jan 2011 A61L27/12

Research output: Patent

Bioceramics
Calcium
Chemical analysis
Alkalies
Silicon

TRANSFER VEHICLE FOR PRODUCING PROTEINS IN TRANSGENIC ANIMALS

Kolb, A. F. 13 Apr 2011 C12N15/85; C12N15/9015 Jun 2009WO2009GB50677 20090615 ; GB20080010924 20080614

Research output: Patent

File
transgenic animals
gene transfer
Retroviridae
Adenoviridae
transgenes
2010

1,5-Diaryl-pyrazoles and their use as cannabinoid receptor neutral antagonists

Greig, I. R. & Ross, R. A. 25 Feb 2010 WO2010020762

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cannabinoid Receptors
Breast Neoplasms
Smoking
Patents and inventions
Salts
Pharmaceutical Preparations
xanthylium

Antibodies specifically directed to a soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N. 2 Sep 2010 15 Apr 2014

Research output: Patent

File
HLA-D Antigens
Antibodies

Antigen Binding Domains from Fish

Dooley, H., Porter, A. J. R. & Flajnik, M. F. 3 Mar 2010 C07K 16/00; 16/18; 15/6310 Aug 2001GB0119553; GB0210508

Research output: Patent

File
Fish
Antigens
Immunoglobulin Isotypes
DNA sequences

Aryl-phenyl-sulfonamide-cycloalkyl compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J. & Tufnell, A. R. 25 Mar 2010 WO2010/032009

Research output: Patent

Aryl-phenyl-sulfonamide-phenylene compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J., Tufnell, A. R. & van 't Hof, R. J. 25 Mar 2010 WO2010/032010

Research output: Patent

File
Sulfonamides
Bone and Bones
Rheumatoid Arthritis
Bone Neoplasms
Psoriatic Arthritis

Biomedical materials

Gibson, I. R., Skakle, J., Smith, N. & Buckland, T. 23 Dec 2010 A61K49/06

Research output: Patent

gadolinium
calcium
phosphate
material
chemical
File
tau Proteins
Hydrates
Labels
Salts
Ligands
positrons
inventions
marking
emitters
platforms

Silicate-substituted hydroxyapatite

Gibson, I. R. & Skakle, J. 8 Jul 2010 A61L27/12

Research output: Patent

Silicates
Durapatite
Carbonates
Biocompatible Materials
Silicon
2009

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Idris, A. I. & Van't Hof, R. J. 2009

Research output: Patent

Neuroprotective 3-phenylacrylonitrile (3-PAN) derivatives

Greig, I. R., Teismann, P., Hanisch, U-K. & Bruck, W. 16 Sep 2009 GB2458259

Research output: Patent

Derivatives
Hydrogen
Neurodegenerative diseases
Chemical analysis
Pharmaceutical Preparations

New pharmaceutical formulation comprising cannabidiol and tetrahydrocannabivarin

Pertwee, R. G., Guy, G. W. & Whittle, B. 15 Jan 2009 A61K31/05; A61K31/352; A61K36/185; A61P19/08;

Research output: Patent

Cannabidiol
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Drug Compounding
Cannabinoids
File
Dosage Forms
Therapeutic Uses
Pharmacokinetics

Treatment and Diagnosis of Behavioural Disorders

Miedzybrodzka, Z. H., St Clair, D. M., Muller, B. M., Neves-Pereira, M. D. L. & Massie, D. 2009 C12Q 1/68 (2006.01)

Research output: Patent

Pharmaceutical Preparations

US20120107320 - Antibodies specifically directed to the soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N. 28 Feb 2009 US20120107320

Research output: Patent

HLA-D Antigens
Antibodies

Use of tetrahydrocannabinol and/or cannabidiol for the treatment of inflammatory bowel disease

Pertwee, R. G., Guy, G. W., Jamontt, J. & Robson, P. 8 Jan 2009 A61K31/05; A61K31/352; A61K36/185; A61P19/08;

Research output: Patent

Cannabidiol
Dronabinol
Inflammatory Bowel Diseases
Cannabinoids

1,5-diaryl-pyrazoles as cannabinoid receptor neutral antagonists useful as therapeutic agents

Greig, I. R., Ross, R. A. & Pertwee, R. G. 21 Aug 2008 A61K31/415; A61P29/00; C07D231/12;

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cognition
Smoking
Osteitis Deformans

2',4'-Dichloro-biphenyl-4-yl-hydroxyketones and related compounds and their use as therapeutic agents

Greig, I. R., Van T Hof, R. J. & Ralston, S. 11 Sep 2008 US20080221220

Research output: Patent

Biphenyl-4-yl-sulfonic acid arylamines and their use as therapeutic agents

Greig, I. R., van't Hof, R. J. & Ralston, S. 2008

Research output: Patent

Chimeric binding peptide library screening method

McGregor, D. 11 Sep 2008 13 Nov 20079718455.0

Research output: Patent

File
Peptide Library
Peptides
DNA-Binding Proteins
Gene Library
DNA

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Van T Hof, R. J. & Mohamed, A. I. I. 18 Dec 2008 US7598289

Research output: Patent

New use for cannabinoid

Pertwee, R. G. & Guy, G. W. 21 Oct 2008 A61K31/00; A61K31/33; A61K31/454;

Research output: Patent

Cannabinoid Receptor CB1
Cannabinoids
Obesity
Cannabinoid Receptor Antagonists
Appetite Depressants

Therapeutic uses of cannabigerol

Pertwee, R. G. 31 Dec 2008 A61K31/352; A61K36/185; A61P25/28; (+3)

Research output: Patent

Therapeutic Uses
Brain Injuries
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Cachexia
1 Citations

Use for cannabinoid

Pertwee, R. G. & Guy, G. W. 22 May 2008 A61K31/353; A61K36/185; A61K31/352;

Research output: Patent

Cannabinoids
Obesity
Cannabinoid Receptors
Bulimia
Nicotine
2007

Cancer Therapy Prognosis and Target

Collie-Duguid, E. S. R., Petty, R. D. & Kerr, K. M. 2007

Research output: Patent

File
Synucleins
Parkinson Disease
Proteins

New use for cannabinoid

Pertwee, R. G. & Guy, G. 6 Dec 2007 A61K31/05; A61K31/352; A61P19/08;

Research output: Patent

Cannabinoids
Cannabidiol
Cannabinoid Receptor CB2