Medicine, Medical Sciences & Nutrition

  • AB25 2ZD

Research Output 1970 2019

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Patent
2017

Synthetic retinoids for use in RAR mediated conditions

Greig, I. R., McCaffery, P. J. A., Whiting, A., Valentine, R., Chisholm, D. & Khatib, T., 12 Oct 2017, Patent No. WO2017174999

Research output: Patent

Retinoids

PATENT: Antibody molecules and uses thereof.

Gow, N. A. R., Rudkin, F. M., Erwig, L-P. & Jensen, A., 15 Sep 2016, IPC No. C07K 16/14 , G01N 33/53, World Intellectual Property Organization, Patent No. WO 2016/142660 Al, 4 Mar 2016, Priority date 6 Mar 2015, Priority No. GB 1503812.8

Research output: Patent

Antibodies
Candida
Fungal Antigens
Gene Targeting
Cell Extracts
2015

Phenothiazine compounds for treating mild cognitive impairment

Wischik, C. M., Harbaran, D. V., Riedel, G., Deiana, S., Goatman, E. A., Wischik, D. J., Murray, A. D. & Staff, R. T., 15 Dec 2015, Patent No. US9211294, 17 Jun 2008, Priority date 19 Jun 2007, Priority No. 60/945006

Research output: Patent

Cognitive Dysfunction
phenothiazine

Polyethylene glycol derivatives of palmitoylethanolamide and analogous acylethanolamides

D'Agostino, G., 13 Jun 2015, Patent No. CA2836069 A1, Priority date 13 Dec 2012

Research output: Patent

2014
1 Downloads (Pure)

Fish Vaccine

Wawra, S., Van West, P. & Secombes, C. J., 4 Dec 2014, IPC No. A61K38/16; C07K14/37; C12N15/62, Patent No. WO2014191759, Priority date 30 May 2013, Priority No. GB20130009664 20130530

Research output: Patent

vaccines
fish
nucleic acids
eukaryotic cells
plasma membrane

Fluoro-perhexiline compounds and their therapeutic use

Greig, I. R., Tseng, C-C. & Zanda, M., 30 Oct 2014, Patent No. WO2014184561

Research output: Patent

ISOLATION OF THERAPEUTIC TARGET SPECIFIC VNAR DOMAINS TO ICOSL

Barelle, C., Finlay, J. J. W. & Darmanin-Sheehan, A., 30 Oct 2014, IPC No. C07K16/00; C07K16/18; C12N15/13, Priority date 23 Apr 2013, Priority No. US201361815043P 20130423

Research output: Patent

Antigen Receptors
Libraries
Sharks
Ligands
Squalus acanthias
2013

18f-labelled barbiturate compounds for use as positron emission imaging agents

Greig, I. R., Zanda, M., Platt, B. & Calamai, E., 21 Mar 2013, Patent No. WO2013038153

Research output: Patent

Aryl-Phenyl-Sulfonamido-Cycloalkyl Compounds and Their Use

Greig, I. R., Sheridan, R. M., Fisher, R., Tozer, M. J., Clase, J. A., Smith, A., Tufnell, A. R. & van 't Hof, R. J., 19 Sep 2013, Patent No. US2013245018

Research output: Patent

Bone and Bones
Rheumatoid Arthritis
Anistreplase
Bone Neoplasms
Psoriatic Arthritis

SINGLE DOMAIN BINDING MOLECULE

Barelle, C., Muller, M., Calabro, V., Bikker, J., Steven, J., Tchistiakova, L., Kovalenko, O. V. & Olland, A., 14 Nov 2013, IPC No. C07K16/46, Priority No. US201313889134 20130507 ; US201261643407P 20120507

Research output: Patent

Open Access
File
Complementarity Determining Regions
Patents and inventions
Serum Albumin
Amino Acids
Molecules
2 Downloads (Pure)

USE OF PLATELET GLYCOPEPTIDE IIIA EPITOPES IN THE TREATMENT OF IMMUNE THROMBOCYTOPENIC PURPURA

Urbaniak, S., Barker, R. N. & Sukati, H. M., 27 Mar 2013, IPC No. A61K38/10; A61P7/00, Patent No. EP2120992, Priority date 18 Jan 2007, Priority No. GB0701048

Research output: Patent

Open Access
Idiopathic Thrombocytopenic Purpura
Glycopeptides
Epitopes
Blood Platelets
Autoantibodies
2011
6 Downloads (Pure)
File
Salt
Drugs
Alzheimer's Disease
Invention

Bone Graft System

Gibson, I. R., Skakle, J., Annaz, B. & Conway, J., 29 Dec 2011, IPC No. A61L27/46, Patent No. WO2011GB00939

Research output: Patent

Hydrogel
Silicon
Grafts
Bone
Durapatite

N-(ARYLALKYL)-1H-INDOLE-2-SULFONIC ACID AMIDE COMPOUNDS AND THEIR THERAPEUTIC USE AS CANNABINOID ALLOSTERIC MODULATORS

Greig, I. R., Ross, R. A., Trembleau, L. A. C., Pertwee, R. G. & Abdelrahman, M. H., 28 Feb 2011, IPC No. WO2012117216, Patent No. WO2012117216

Research output: Patent

Cannabinoid Receptors
Sulfonic Acids
Cannabinoids
Therapeutic Uses
Amides

Synthesis of Bioceramic Compositions

Gibson, I. R. & Skakle, J., 27 Jan 2011, IPC No. A61L27/12, Patent No. US20110021338

Research output: Patent

Bioceramics
Calcium
Chemical analysis
Alkalies
Silicon

TRANSFER VEHICLE FOR PRODUCING PROTEINS IN TRANSGENIC ANIMALS

Kolb, A. F., 13 Apr 2011, IPC No. C12N15/85; C12N15/90, Priority date 15 Jun 2009, Priority No. WO2009GB50677 20090615 ; GB20080010924 20080614

Research output: Patent

File
transgenic animals
gene transfer
Retroviridae
Adenoviridae
transgenes
2010

1,5-Diaryl-pyrazoles and their use as cannabinoid receptor neutral antagonists

Greig, I. R. & Ross, R. A., 25 Feb 2010, IPC No. WO2010020762, Patent No. WO2010020762

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cannabinoid Receptors
Breast Neoplasms
Smoking
Patents and inventions
Salts
Pharmaceutical Preparations
xanthylium
26 Downloads (Pure)

Antibodies specifically directed to a soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N., 2 Sep 2010, Patent No. US8697845 B2, Priority date 15 Apr 2014

Research output: Patent

File
HLA-D Antigens
Antibodies
16 Downloads (Pure)

Antigen Binding Domains from Fish

Dooley, H., Porter, A. J. R. & Flajnik, M. F., 3 Mar 2010, IPC No. C07K 16/00; 16/18; 15/63, Patent No. 1419179, Priority date 10 Aug 2001, Priority No. GB0119553; GB0210508

Research output: Patent

File
Fish
Antigens
Immunoglobulin Isotypes
DNA sequences

Aryl-phenyl-sulfonamide-cycloalkyl compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J. & Tufnell, A. R., 25 Mar 2010, IPC No. WO2010/032009 , Patent No. WO2010/032009

Research output: Patent

1 Downloads (Pure)

Aryl-phenyl-sulfonamide-phenylene compounds and their use

Greig, I. R., Clase, J. A., Fisher, R., Sheridan, R. M., Smith, A., Tozer, M. J., Tufnell, A. R. & van 't Hof, R. J., 25 Mar 2010, IPC No. WO2010/032010, Patent No. WO2010/032010

Research output: Patent

File
Sulfonamides
Bone and Bones
Rheumatoid Arthritis
Bone Neoplasms
Psoriatic Arthritis

Biomedical materials

Gibson, I. R., Skakle, J., Smith, N. & Buckland, T., 23 Dec 2010, IPC No. A61K49/06, Patent No. US20100322867

Research output: Patent

gadolinium
calcium
phosphate
material
chemical
7 Downloads (Pure)
File
tau Proteins
Hydrates
Labels
Salts
Ligands

Materials and methods for medical imaging

Smith, T. A. D., Trembleau, L. A. C., McLaughlin, A. & Simpson, M., 2010, IPC No. WO2009056837, Patent No. GB2467494 (A)

Research output: Patent

positrons
inventions
marking
emitters
platforms

Silicate-substituted hydroxyapatite

Gibson, I. R. & Skakle, J., 8 Jul 2010, IPC No. A61L27/12, Patent No. US20100173009

Research output: Patent

Silicates
Durapatite
Carbonates
Biocompatible Materials
Silicon
2009

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Idris, A. I. & Van't Hof, R. J., 2009, Patent No. US7598289

Research output: Patent

Neuroprotective 3-phenylacrylonitrile (3-PAN) derivatives

Greig, I. R., Teismann, P., Hanisch, U-K. & Bruck, W., 16 Sep 2009, IPC No. GB2458259, Patent No. GB2458259

Research output: Patent

Derivatives
Hydrogen
Neurodegenerative diseases
Chemical analysis
Pharmaceutical Preparations

New pharmaceutical formulation comprising cannabidiol and tetrahydrocannabivarin

Pertwee, R. G., Guy, G. W. & Whittle, B., 15 Jan 2009, IPC No. A61K31/05; A61K31/352; A61K36/185; A61P19/08;, Patent No. WO2009007697

Research output: Patent

Cannabidiol
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Drug Compounding
Cannabinoids
2 Downloads (Pure)

Therapeutic Use of Diaminophenothiazines: WO2009044127

Wischik, C. M., Damon J., W., Storey, J. M. D. & Harrington, C. R., 9 Apr 2009, IPC No. WO2009/044127

Research output: Patent

File
Dosage Forms
Therapeutic Uses
Pharmacokinetics

Treatment and Diagnosis of Behavioural Disorders

Miedzybrodzka, Z. H., St Clair, D. M., Muller, B. M., Neves-Pereira, M. D. L. & Massie, D., 2009, IPC No. C12Q 1/68 (2006.01), Patent No. WO/2009/144480

Research output: Patent

Pharmaceutical Preparations

US20120107320 - Antibodies specifically directed to the soluble form of CTLA-4

Ward, F. J., Barker, R. N. & Dahal, L. N., 28 Feb 2009, IPC No. US20120107320

Research output: Patent

HLA-D Antigens
Antibodies

Use of tetrahydrocannabinol and/or cannabidiol for the treatment of inflammatory bowel disease

Pertwee, R. G., Guy, G. W., Jamontt, J. & Robson, P., 8 Jan 2009, IPC No. A61K31/05; A61K31/352; A61K36/185; A61P19/08; , Patent No. WO2009004302

Research output: Patent

Cannabidiol
Dronabinol
Inflammatory Bowel Diseases
Cannabinoids
2008

[11C]Methoxy-radiolabelled 2,3',4,5' - Tetramethoxystilbene (TMS) and its preparation and use8

Schweiger, L. & Smith, T. A. D., 2008, Patent No. WO2009001046

Research output: Patent

1,5-diaryl-pyrazoles as cannabinoid receptor neutral antagonists useful as therapeutic agents

Greig, I. R., Ross, R. A. & Pertwee, R. G., 21 Aug 2008, IPC No. A61K31/415; A61P29/00; C07D231/12; , Patent No. WO2008/099139

Research output: Patent

Pyrazoles
Cannabinoid Receptor Antagonists
Cognition
Smoking
Osteitis Deformans

2',4'-Dichloro-biphenyl-4-yl-hydroxyketones and related compounds and their use as therapeutic agents

Greig, I. R., Van T Hof, R. J. & Ralston, S., 11 Sep 2008, IPC No. US20080221220, Patent No. US20080221220

Research output: Patent

Biphenyl-4-yl-sulfonic acid arylamines and their use as therapeutic agents

Greig, I. R., van't Hof, R. J. & Ralston, S., 2008, Patent No. WO2008/114022

Research output: Patent

Chimeric binding peptide library screening method

McGregor, D., 11 Sep 2008, Priority date 13 Nov 2007, Priority No. 9718455.0

Research output: Patent

File
Peptide Library
Peptides
DNA-Binding Proteins
Gene Library
DNA

Ketones and reduced ketones as therapeutic agents for the treatment of bone conditions

Greig, I. R., Ralston, S., Van T Hof, R. J. & Mohamed, A. I. I., 18 Dec 2008, IPC No. US7598289, Patent No. US7598289

Research output: Patent

New use for cannabinoid

Pertwee, R. G. & Guy, G. W., 21 Oct 2008, IPC No. A61K31/00; A61K31/33; A61K31/454; , Patent No. BRPI0518011

Research output: Patent

Cannabinoid Receptor CB1
Cannabinoids
Obesity
Cannabinoid Receptor Antagonists
Appetite Depressants

Therapeutic uses of cannabigerol

Pertwee, R. G., 31 Dec 2008, IPC No. A61K31/352; A61K36/185; A61P25/28; (+3), Patent No. WO2009001081

Research output: Patent

Therapeutic Uses
Brain Injuries
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
Cachexia
1 Citation (Scopus)

Use for cannabinoid

Pertwee, R. G. & Guy, G. W., 22 May 2008, IPC No. A61K31/353; A61K36/185; A61K31/352; , Patent No. US2008119544

Research output: Patent

Cannabinoids
Obesity
Cannabinoid Receptors
Bulimia
Nicotine
2007

Cancer Therapy Prognosis and Target

Collie-Duguid, E. S. R., Petty, R. D. & Kerr, K. M., 2007, Patent No. BOA:0519405.5; PCT/GB2006/003559 (23/9/05)

Research output: Patent

1 Downloads (Pure)
File
Synucleins
Parkinson Disease
Proteins

New use for cannabinoid

Pertwee, R. G. & Guy, G., 6 Dec 2007, IPC No. A61K31/05; A61K31/352; A61P19/08; , Patent No. WO200713822

Research output: Patent

Cannabinoids
Cannabidiol
Cannabinoid Receptor CB2