Research Output 1978 2020

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2020
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Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, dmm042655.

Research output: Contribution to journalArticle

Open Access
File
Congenital Generalized Lipodystrophy
Ablation
Hepatocytes
Liver
Lipids

A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 13 Jan 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

Assays
Cells
Health
Vegetables
Hep G2 Cells
1 Downloads (Pure)

Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin

Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K-M., Russell, W. R., Scobbie, L. & Hoggard, N., Jan 2020, In : Journal of Functional Foods. 64, 103597.

Research output: Contribution to journalArticle

Open Access
File
Vaccinium myrtillus
bilberries
Anthocyanins
volunteers
anthocyanins

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 17 Feb 2020, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Ethanol
Galanin
Anxiety
Genotype
Single-Payer System
Scotland
Length of Stay
Emergencies
Delivery of Health Care

Lung function and microbiota diversity in cystic fibrosis

Cuthbertson, L., Walker, A., Oliver, A., Rogers, G. B., Rivett, D., Hampton, T., Ashare, A., Elborn, S., De Soyza, A., Carroll, M., Hoffman, L. R., Lanyon, C., Moskowitz, S., O'Toole, G., Parkhill, J., Planet, P., Teneback, C., Tunney, M., Zuckerman, J., Bruce, K. D. & 1 others, van der Gast, C., 19 Feb 2020, (Accepted/In press) In : Microbiome.

Research output: Contribution to journalArticle

Multi-mycotoxin exposure assessment in UK children using urinary biomarkers - a pilot survey

Gratz, S. W., Currie, V., Duncan, G. & Jackson, D., 2020, In : Journal of Agricultural and Food Chemistry. 68, 1, p. 351-357 7 p.

Research output: Contribution to journalArticle

exposure assessment
Mycotoxins
Biomarkers
mycotoxins
biomarkers

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

Sim, M. F. M., Persiani, E., Talukder, M. M. U., McIlroy, G., Roumane, A., Edwardson, J. M. & Rochford, J., 27 Jan 2020, (Accepted/In press) In : Scientific Reports.

Research output: Contribution to journalArticle

Congenital Generalized Lipodystrophy
Lipodystrophy
Adipogenesis
Adipocytes
Enzymes

Ovine prenatal growth-restriction and sex influence fetal adipose tissue phenotype and impact postnatal lipid metabolism and adiposity in vivo from birth until adulthood

Wallace, J. M., Milne, J. S., Aitken, B. W., Aitken, R. P. & Adam, C. L., 14 Feb 2020, In : PloS ONE. 15, 2, e0228732.

Research output: Contribution to journalArticle

Open Access
File
prenatal development
Adiposity
adiposity
adulthood
Lipid Metabolism

Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation

Karnani, M. M., Schöne, C., Bracey, E. F., González, J. A., Viskaitis, P., Li, H-T., Adamantidis, A. & Burdakov, D., 11 Feb 2020, In : Progress in Neurobiology.

Research output: Contribution to journalArticle

Open Access
Locomotion
Neurons
Food Deprivation
Orexins
Sensory Receptor Cells
Open Access
Candida
Bedding and Linens
Laundering
Delivery of Health Care
Infectious Disease Transmission
eating behavior
eating habits
Eating
ingestion
Dietary Guidelines
2019
Open Access
Inguinal Hernia
Herniorrhaphy
Reoperation
Scotland
Cohort Studies
3 Citations (Scopus)
2 Downloads (Pure)

Activity energy expenditure is an independent predictor of energy intake in humans

Hopkins, M., Duarte, C., Beaulieu, K., Finlayson, G., Gibbons, C., Johnstone, A., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 1 Jul 2019, In : International Journal of Obesity. 43, 7, p. 1466–1474 9 p.

Research output: Contribution to journalArticle

Open Access
File
Energy Intake
Energy Metabolism
Basal Metabolism
Body Composition
Diet Records

Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

Research output: Contribution to journalArticle

Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Glutathione
Zinc
1 Citation (Scopus)
5 Downloads (Pure)

A high-fat diet induces rapid changes in the mouse hypothalamic proteome

McLean, F. H., Campbell, F. M., Langston, R. F., Sergi, D., Resch, C., Grant, C., Morris, A., Mayer, C-D. & Williams, L. M., 29 Apr 2019, In : Nutrition and Metabolism. 16, 26.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Oleic Acid
Neuronal Plasticity
8 Downloads (Pure)
Open Access
File
Meats
consumption behavior
campaign
social marketing
Health
1 Citation (Scopus)
Streptomyces griseus
Lactalbumin
Pronase
lactalbumin
enzymatic treatment

Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., 16 Oct 2019, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 102024.

Research output: Contribution to journalArticle

Endocannabinoids
Ethanolamine
Cell growth
Breast Neoplasms
Derivatives

A pilot study to improve sugar and water consumption in Maltese school children

Copperstone, C., McNeill, G., Aucott, L. & Jackson, D. M., 15 Feb 2019, In : International Journal of Adolescent Medicine and Health.

Research output: Contribution to journalArticle

Drinking
Pediatric Obesity
Energy Intake
Health Promotion
Drinking Water

Application of the Dynamic Gastrointestinal Simulator (simgi®) to assess the impact of probiotic supplementation in the metabolism of grape polyphenols

Gil-Sánchez, I., Cueva, C., Tamargo, A., Quintela, J. C., de la Fuente, E., Walker, A. W., Moreno-Arribas, M. V. & Bartolomé, B., 21 Nov 2019, In : Food Research International. 129, 108790.

Research output: Contribution to journalArticle

Vitis
Probiotics
Polyphenols
Lactobacillus plantarum
probiotics
2 Citations (Scopus)
1 Downloads (Pure)

Appropriate age range for introduction of complementary feeding into an infant’s diet

Castenmiller, J., de Henauw, S., Hirsch-Ernst, K-I., kearney, J., Knutsen, H. K., Maciuk, A., Mangelsdorf, I., McArdle, H., Naska, A., Pelaez, C., Pentieva, K., Thies, F., Siani, A., Tsabouri, S., Vincenti, M., Bresson, J-L., Fewtrell, M., Kersting, M., Przyrembel, H., Dumas, C. & 3 others, Titz, A., Turck, D. & EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Sep 2019, In : EFSA Journal. 17, 9, 241 p., e5780.

Research output: Contribution to journalArticle

Open Access
File
Infant Nutritional Physiological Phenomena
infant feeding
complementary foods
Diet
Food
1 Citation (Scopus)
mayonnaise
chickpeas
Ovum
Oils
droplet size

A simple approach to modelling the soil water budget in Scottish mineral soils

Brand, A. M., Lilly, A. & Smith, J. U., 2019, (In preparation) In : Environmental Modelling and Software.

Research output: Contribution to journalArticle

1 Citation (Scopus)
12 Downloads (Pure)
Open Access
File
eating
diets
Eating
diet
Diet
8 Citations (Scopus)
8 Downloads (Pure)

Biological and psychological mediators of the relationships between fat mass, fat-free mass and energy intake

Hopkins, M., Finlayson, G., Duarte, C., Gibbons, C., Johnstone, A. M., Whybrow, S., Horgan, G. W., Blundell, J. E. & Stubbs, R. J., 2019, In : International Journal of Obesity. 43, p. 233-242 42 p.

Research output: Contribution to journalArticle

Open Access
File
Energy Intake
Fats
Psychology
Basal Metabolism
Leptin

Can Haematology Blood Tests at Time of Diagnosis Predict Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer?

Ramsay, G., Ritchie, D. T., MacKay, C., Parnaby, C., Murray, G. & Samuel, L., Oct 2019, In : Digestive Surgery. 36, 6, p. 495–501 7 p.

Research output: Contribution to journalArticle

Neoadjuvant Therapy
Hematologic Tests
Hematology
Rectal Neoplasms
Area Under Curve

Cinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion

Hayward, N. J., McDougall, G. J., Farag, S., Allwood, J. W., Austin, C., Campbell, F., Horgan, G. & Ranawana, V., Dec 2019, In : Plant Foods for Human Nutrition. 74, 4, p. 544-552 9 p.

Research output: Contribution to journalArticle

Open Access
File
Cinnamomum zeylanicum
Hypoglycemic Agents
Starch
Digestion
Cinnamomum aromaticum
1 Citation (Scopus)
6 Downloads (Pure)

Clinical decisions and time since rest break: An analysis of decision fatigue in nurses

Allan, J. L., Johnston, D. W., Powell, D. J. H., Farquharson, B., Jones, M. C., Leckie, G. & Johnston, M., Apr 2019, In : Health Psychology. 38, 4, p. 318-324 7 p.

Research output: Contribution to journalArticle

Open Access
File
Decision Support Techniques
Fatigue
Nurses
Health
Workload

Co-ingestion of whey protein hydrolysate with milk minerals rich in calcium potently stimulates glucagon-like peptide-1 secretion: an RCT in healthy adults

Chen, Y-C., Smith, H. A., Hengist, A., Chrzanowski-Smith, O. J., Mikkelsen, U. R., Carroll, H. A., Betts, J. A., Thompson, D., Saunders, J. & Gonzalez, J. T., 17 Sep 2019, In : European Journal of Nutrition. 14 p.

Research output: Contribution to journalArticle

Open Access
Protein Hydrolysates
Glucagon-Like Peptide 1
Minerals
Milk
Eating
1 Citation (Scopus)

Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier and immune defense defects

Aviello, G., Singh, A. K., O’Neill, S., Conroy, E., Gallagher, W., D’Agostino, G., Walker, A. W., Bourke, B., Scholz, D. & Knaus, U. G., Nov 2019, In : Mucosal Immunology. 12, p. 1316-1326 11 p.

Research output: Contribution to journalArticle

Colitis
Mucus
Reactive Oxygen Species
Inflammation
Dysbiosis
1 Downloads (Pure)

Comparative genomics and genome biology of Campylobacter showae

Hsu, T., Gemmell, M. R., Franzosa, E. A., Berry, S. H., Mukhopadhya, I., Hansen, R., Michaud, M., Nielsen, H., Miller, W. G., Nielsen, H., Bajaj-Elliott, M., Huttenhower, C., Garrett, W. S. & Hold, G. L., 2019, In : Emerging Microbes and Infections. 8, 1, p. 827-840 14 p.

Research output: Contribution to journalArticle

Open Access
File
Campylobacter
Genomics
Genome
Genes
CRISPR-Associated Proteins
3 Citations (Scopus)
1 Downloads (Pure)

Compendium of 4,941 rumen metagenome-assembled genomes for rumen microbiome biology and enzyme discovery

Stewart, R. D., Auffret, M. D., Warr, A., Walker, A. W., Roehe, R. & Watson, M., 2 Aug 2019, In : Nature Biotechnology. 37, p. 953–961 9 p.

Research output: Contribution to journalArticle

Open Access
File
Metagenome
Microbiota
Rumen
Enzymes
Genes
5 Citations (Scopus)
Endocrine System
Mothers
Food
Growth
Sheep

Developments in understanding and applying prebiotics in research and practice: an ISAPP conference paper

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A., Tang, M. L. K., Lee, J. C-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. & Gibson, G. R., 12 Sep 2019, In : Journal of Applied Microbiology.

Research output: Contribution to journalArticle

Open Access
Prebiotics
Insurance Benefits
Research
Literature
Food Industry
2 Citations (Scopus)
1 Downloads (Pure)

Dietary carbohydrate rather than protein intake drives colonic microbial fermentation during weight loss

Gratz, S. W., Hazim, S., Richardson, A. J., Scobbie, L., Johnstone, A. M., Fyfe, C., Holtrop, G., Lobley, G. E. & Russell, W. R., Apr 2019, In : European Journal of Nutrition. 58, 3, p. 1147-1158 12 p.

Research output: Contribution to journalArticle

Open Access
File
Dietary Carbohydrates
Fermentation
Weight Loss
Reducing Diet
Carbohydrates
4 Downloads (Pure)

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

Jiao, Y., Ahmed, U., Sim, M. F. M., Bejar, A., Zhang, X., Talukder, M. M. U., Rice, R., Flannick, J., Podgornaia, A. I., Reilly, D. F., Engreitz, J. M., Kost-Alimova, M., Hartland, K., Mercader, J-M., Georges, S., Wagh, V., Tadin-Strapps, M., Doench, J. G., Edwardson, J. M., Rochford, J. J. & 2 others, Rosen, E. D. & Majithia, A. R., Jun 2019, In : Molecular Metabolism. 24, p. 108-119 12 p.

Research output: Contribution to journalArticle

Open Access
File
Metabolic Diseases
Adipocytes
Genes
Lipodystrophy
Type 2 Diabetes Mellitus
2 Citations (Scopus)
2 Downloads (Pure)
Open Access
File
Addictive Behavior
Cannabinoid Receptors
Cannabinoids
Clustered Regularly Interspaced Short Palindromic Repeats
Anxiety
1 Downloads (Pure)

Early and reversible changes to the hippocampal proteome in mice on a high-fat diet

McLean, F. H., Campbell, F. M., Sergi, D., Grant, C., Morris, A. C., Hay, E. A., MacKenzie, A., Mayer, C-D., Langston, R. F. & Williams, L. M., Dec 2019, In : Nutrition and Metabolism. 16, 1, 12 p., 57.

Research output: Contribution to journalArticle

Open Access
File
High Fat Diet
Proteome
Palmitic Acid
Fat-Restricted Diet
Docosahexaenoic Acids
4 Citations (Scopus)

Effect of acute hypohydration on glycemic regulation in healthy adults: a randomized crossover trial

Carroll, H., Templeman, I., Chen, Y., Edinburgh, R. M., Burch, E. K., Jewitt, J. T., Povey, G., Robinson, T. D., Dooley, W. L., Jones, R., Tsintzas, K., Gallo, W., Melander, O., Thompson, D., James, L. J., Johnson, L. & Betts, J. A., 20 Feb 2019, In : Journal of Applied Physiology. 126, 2, p. 422-430 9 p.

Research output: Contribution to journalArticle

Open Access
File
Glucose Tolerance Test
Cross-Over Studies
Cell Size
Muscles
Computer Peripherals
Open Access
File
Home Care Services
Meta-Analysis
Quality of Life
Registries
Proteins

Fat, carbohydrate and protein by oral gavage in the rat can be equally effective for satiation

Cassie, N., Anderson, R. L., Wilson, D., Mercer, J. G. & Barrett, P., 1 Aug 2019, In : Physiology and Behavior. 207, p. 41-47 7 p.

Research output: Contribution to journalArticle

Satiation
Fats
Carbohydrates
Food
Peptones
1 Citation (Scopus)

Folate, genomic stability and colon cancer: The use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring

Catala, G. N., Bestwick, C. S., Russell, W. R., Tortora, K., Giovannelli, L., Moyer, M. P., Lendoiro, E. & Duthie, S. J., Jul 2019, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 843, p. 73-80 8 p.

Research output: Contribution to journalArticle

Comet Assay
Environmental Monitoring
Genomic Instability
Folic Acid
Colonic Neoplasms

Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes

Kolb, A. F., Petrie, L., Mayer, C. D., Pirie, L. & Duthie, S. J., 2019, In : Biochemical Journal. 476, 19, p. 2769-2795 7 p.

Research output: Contribution to journalArticle

Methylation
Vascular Smooth Muscle
Folic Acid
Smooth Muscle Myocytes
Muscle

Food additives: Assessing the impact of exposure to permitted emulsifiers on bowel and metabolic health – introducing the FADiets study

Partridge, D., Lloyd, K. A., Rhodes, J. M., Walker, A. W., Johnstone, A. M. & Campbell, B. J., 1 Dec 2019, In : Nutrition Bulletin. 44, 4, p. 329-349 21 p.

Research output: Contribution to journalArticle

Open Access
File
Food Additives
Bacterial Translocation
Lecithins
Health
Detergents
1 Citation (Scopus)
6 Downloads (Pure)
Open Access
File
formic acid
Ruminococcus bromii
formates
coculture
Coculture Techniques
2 Citations (Scopus)
3 Downloads (Pure)

Genetic variants in selenoprotein genes modulate biomarkers of selenium status in response to Brazil nut supplementation (the SU.BRA.NUT study)

Donadio, J. L. S., Rogero, M. M., Guerra-Shinohara, E. M., Barbosa Jr., F., Desmarchelier, C., Borel, P., Sneddon, A., Hesketh, J. & Cozzolino, S. M. F., Apr 2019, In : Clinical Nutrition. 38, 2, p. 539-548 10 p.

Research output: Contribution to journalArticle

Open Access
File
Bertholletia
Selenoproteins
Selenium
Biomarkers
Genes
3 Citations (Scopus)
2 Downloads (Pure)

Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify novel mechanisms for seasonal energy balance

Bao, R., Onishi, K. G., Tolla, E., Ebling, F. J. P., Lewis, J. E., Anderson, R. L., Barrett, P., Prendergast, B. J. & Stevenson, T. J., 25 Jun 2019, In : PNAS. 116, 26, p. 13116-13121 6 p.

Research output: Contribution to journalArticle

Open Access
File
Phodopus
Pro-Opiomelanocortin
Gene Expression Profiling
Hypothalamus
Body Weight Changes

Genoprotective Effects of Essential Oil Compounds Against Oxidative and Methylated DNA Damage in Human Colon Cancer Cells

Thapa, D., Richardson, A. J., Zweifel, B., Wallace, R. J. & Gratz, S. W., Jul 2019, In : Journal of Food Science. 84, 7, p. 1979-1985 7 p.

Research output: Contribution to journalArticle

Volatile Oils
colorectal neoplasms
DNA damage
Colonic Neoplasms
DNA Damage