Research Output

2020

Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Mcilroy, G. D., Mitchell, S. E., Han, W., Delibegović, M. & Rochford, J. J., 17 Jan 2020, In : Disease Models & Mechanisms. 13, 1, 10 p., dmm042655.

Research output: Contribution to journalArticle

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A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

Active travelling to school is not associated with increased total daily physical activity levels, or reduced obesity and cardiovascular/pulmonary health parameters in 10–12-year olds: a cross-sectional cohort study

Zhang, X., Smith, N. A., Sumowski, M. T., Anderson, J. M., Anderson, K., Badenoch, E. A., Brady, S. J., Coleman, M., Coull, R. F., Green, D., Innes, R. J., Laing, C. M., Mckinley, R., Mclennan, M. S., Murray, S., Phillips, B., Rae, S., Rankin, S., Satar, I., Shanks, S. & 8 others, Sim, F. J., Walker, N., Howard, D., Sniehotta, F. F., Jackson, D. M., VaanHolt, L. M., Hambly, C. & Speakman, J. R., Jul 2020, In : International Journal of Obesity. 44, p. 1452-1466 15 p.

Research output: Contribution to journalArticle

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Angelova, P. R., Choi, M. L., Berezhnov, A. V., Hughes, C. D., De, S., Rodrigues, M., Little, D., Dolt, K. S., Kunath, T., Devine, M. J., Gissen, P., Shchepinov, M. S., Sylantyev, S., Pavlov, E. V., Klenerman, D., Abramov, A. Y., Gandhi, S. & Horrocks, M., 27 Apr 2020, In : Cell Death and Differentiation. 16 p.

Research output: Contribution to journalArticle

Analysing the impact of living in a rural setting on the presentation and outcome of colorectal cancer: A prospective single centre observational study

MacVicar, E., Ritchie, D., Murchie, P., Parnaby, C., MacKay, C. & Ramsay, G., 14 Mar 2020, In : The Surgeon.

Research output: Contribution to journalArticle

Analysis of 1321 Eubacterium rectale genomes from metagenomes uncovers complex phylogeographic population structure and subspecies functional adaptations

Karcher, N., Pasolli, E., Asnicar, F., Huang, K. D., Tett, A., Manara, S., Armanini, F., Bain, D., Duncan, S. H., Louis, P., Zolfo, M., Manghi, P., Valles-Colomer, M., Raffaetà, R., Rota-Stabelli, O., Collado, M. C., Zeller, G., Falush, D., Maixner, F., Walker, A. W. & 2 others, Huttenhower, C. & Segata, N., 8 Jun 2020, In : Genome Biology. 21, 27 p., 138.

Research output: Contribution to journalArticle

Open Access
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Analysis of polyphenolic metabolites from in vitro gastrointestinal digested soft fruit extracts identify malvidin-3-glucoside as an inhibitor of PTP1B

Barik, S. K., Dehury, B., Russell, W. R., Moar, K-M., Cruickshank, M., Scobbie, L. & Hoggard, N., 20 Jun 2020, In : Biochemical Pharmacology. 178, 15 p., 114109.

Research output: Contribution to journalArticle

Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin

Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K-M., Russell, W. R., Scobbie, L. & Hoggard, N., Jan 2020, In : Journal of Functional Foods. 64, 103597.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
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Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., May 2020, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 156, 10 p., 102024.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Application of the Dynamic Gastrointestinal Simulator (simgi®) to assess the impact of probiotic supplementation in the metabolism of grape polyphenols

Gil-Sánchez, I., Cueva, C., Tamargo, A., Quintela, J. C., de la Fuente, E., Walker, A. W., Moreno-Arribas, M. V. & Bartolomé, B., Mar 2020, In : Food Research International. 129, 108790.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1 Citation (Scopus)

A simple approach to modelling the soil water budget in cool temperate mineral topsoils

Brand, A., Lilly, A. & Smith, J., May 2020, In : Environmental Modelling and Software. 127, 14 p., 104700.

Research output: Contribution to journalArticle

Challenges of the heterogeneous nutrition response: interpreting the group mean

Drew, J. E., May 2020, In : Proceedings of the Nutrition Society. 79, 2, p. 174-183 10 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)

Circulating asymmetric dimethylarginine and cognitive decline: A 4‐year follow‐up study of the 1936 Aberdeen Birth Cohort

Malden, D. E., Mangoni, A. A., Woodman, R. J., Thies, F., McNeil, C., Murray, A. D. & Soiza, R. L., 8 Jun 2020, In : International Journal of Geriatric Psychiatry. 8 p.

Research output: Contribution to journalArticle

Open Access

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Current practice of anticoagulant in the treatment of splanchnic vein thrombosis secondary to acute pancreatitis

Norton, W., Lazaraviciute, G., Ramsay, G., Kreis, I., Ahmed, I. & Bekheit, M., Apr 2020, In : Hepatobiliary and Pancreatic Diseases International. 19, 2, p. 116-121 6 p.

Research output: Contribution to journalReview article

Developments in understanding and applying prebiotics in research and practice: an ISAPP conference paper

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A., Tang, M. L. K., Lee, J. C-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. & Gibson, G. R., Apr 2020, In : Journal of Applied Microbiology. 128, 4, p. 934-949 16 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies

Mayer, C-D., de La Giclais, S. M., Alsehly, F. & Hoppler, S., May 2020, In : Genes. 11, 5, 23 p., 538.

Research output: Contribution to journalArticle

Open Access
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Ecological momentary assessment of mood and physical activity in people with depression

Hollands, L., Lambert, J., Price, L., Powell, D. & Greaves, C., 15 Jun 2020, In : Journal of Affective Disorders. 271, p. 293-299 7 p.

Research output: Contribution to journalArticle

Effect of Plain Versus Sugar-Sweetened Breakfast on Energy Balance and Metabolic Health: A Randomized Crossover Trial

Carroll, H. A., Chen, Y-C., Templeman, I. S., Wharton, P., Reeves, S., Trim, W. V., Chowdhury, E. A., Brunstrom, J. M., Rogers, P. J., Thompson, D., James, L. J., Johnson, L. & Betts, J. A., Apr 2020, In : Obesity. 28, 4, p. 740-748 9 p.

Research output: Contribution to journalArticle

Open Access
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Evaluation of bacterial biomarkers to aid in challenging inflammatory bowel diseases diagnostics and subtype classification

Lopez-Siles, M., Aldeguer, X., Sabat-Mir, M., Serra-Pagès, M., Duncan, S. H., Flint, H. J., Garcia-Gil, L. J. & Martinez-Medina, M., 12 May 2020, In : World Journal of Gastrointestinal Pathophysiology. 11, 3, p. 64-77 14 p.

Research output: Contribution to journalArticle

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Inter-individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption: a Critical Review

Visser, E., Geleijnse, J. M. & de Roos, B., Apr 2020, In : Molecular Nutrition & Food Research. 64, 7, 22 p., e1900479.

Research output: Contribution to journalReview article

Iron deficiency during pregnancy and lactation modifies the fatty acid composition of the brain of neonatal rats

Rees, W. D., Hay, S. M., Hayes, H. E., Stevens, V. J., Gambling, L. & McArdle, H. J., Jun 2020, In : Journal of Developmental Origins of Health and Disease. 11, 3, p. 264-272 9 p.

Research output: Contribution to journalArticle

Lung function and microbiota diversity in cystic fibrosis

Cuthbertson, L., Walker, A. W., Oliver, A. E., Rogers, G. B., Rivett, D. W., Hampton, T. H., Ashare, A., Elborn, S., De Soyza, A., Carroll, M., Hoffman, L. R., Lanyon, C., Moskowitz, S., O'Toole, G., Parkhill, J., Planet, P. J., Teneback, C., Tunney, M., Zuckerman, J., Bruce, K. D. & 1 others, van der Gast, C., 2 Apr 2020, In : Microbiome. 8, 13 p., 45.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
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Multi-mycotoxin exposure assessment in UK children using urinary biomarkers - a pilot survey

Gratz, S. W., Currie, V., Duncan, G. & Jackson, D., 2020, In : Journal of Agricultural and Food Chemistry. 68, 1, p. 351-357 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Neurochemical characterization of brainstem Pro-opiomelanocortin cells

Georgescu, T., Lyons, D., Doslikova, B., Garcia, A. P., Marston, O., Burke, L. K., Chianese, R., Lam, B. Y. H., Yeo, G. S. H., Rochford, J. J., Garfield, A. S. & Heisler, L. K., Apr 2020, In : Endocrinology. 161, 4, p. 1-13 13 p., bqaa032.

Research output: Contribution to journalArticle

Open Access
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Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

Sim, M. F. M., Persiani, E., Talukder, M. M. U., McIlroy, G., Roumane, A., Edwardson, J. M. & Rochford, J., 24 Feb 2020, In : Scientific Reports. 10, 3259.

Research output: Contribution to journalArticle

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Oral bacterial diversity is inversely correlated with mucosal inflammation

Hijazi, K., Morrison, R. W., Mukhopadhya, I., Martin, B., Gemmell, M., Shaw, S. & Santoro, F., 3 Jun 2020, In : Oral Diseases. 10 p.

Research output: Contribution to journalArticle

Open Access

Ovarian hormones induce de novo DNA methyltransferase expression in the Siberian hamster suprachiasmatic nucleus

Coyle, C. S., Caso, F., Tolla, E., Barrett, P., Onishi, K. G., Tello, J. A. & Stevenson, T. J., Feb 2020, In : Journal of Neuroendocrinology. 32, 2, 10 p., e12819.

Research output: Contribution to journalArticle

Ovine prenatal growth-restriction and sex influence fetal adipose tissue phenotype and impact postnatal lipid metabolism and adiposity in vivo from birth until adulthood

Wallace, J. M., Milne, J. S., Aitken, B. W., Aitken, R. P. & Adam, C. L., 14 Feb 2020, In : PloS ONE. 15, 2, e0228732.

Research output: Contribution to journalArticle

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Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4

Sergi, D., Morris, A. C., Kahn, D. E., McLean, F. H., Hay, E. A., Kubitz, P., MacKenzie, A., Martinoli, M. G., Drew, J. E. & Williams, L. M., 2020, In : Nutritional Neuroscience. 23, 4, p. 321-334 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Pharmacokinetic Profile of Plasma Levobupivacaine Following Fascia Iliaca Compartment Block for Proximal Femoral Fracture in Older Patients

Parr, R., Robinson, H., Cameron, G., Broadbent, G., Wallace, H. & Engelhardt, T., 15 Jun 2020, In : Pharmaceutical and Biomedical Research. 6, 2, p. 57-70 14 p.

Research output: Contribution to journalArticle

Open Access

Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity

Sergi, D. & Williams, L. M., Apr 2020, In : Nutrition Reviews. 78, 4, p. 261-277 17 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Role of spontaneous and sensory orexin network dynamics in rapid locomotion initiation

Karnani, M. M., Schöne, C., Bracey, E. F., González, J. A., Viskaitis, P., Li, H-T., Adamantidis, A. & Burdakov, D., Apr 2020, In : Progress in Neurobiology. 187, 17 p., 101771.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
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1 Citation (Scopus)
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3 Citations (Scopus)
2 Downloads (Pure)
Open Access

The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction

Sergi, D., Boulestin, H., Campbell, F. M. & Williams, L. M., 20 Apr 2020, In : Molecular Nutrition & Food Research. 1900934.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Vitamin biosynthesis by human gut butyrate-producing bacteria and cross-feeding in synthetic microbial communities

Soto Martin, E., Warnke, I., Farquharson, F., Christodoulou, M., Horgan, G., Derrien, M., Faurie, J-M., Flint, H. J., Duncan, S. & Louis, P., 15 Jun 2020, (Accepted/In press) In : mBio.

Research output: Contribution to journalArticle

We are what we (think we) eat: The effect of expected satiety on subsequent calorie consumption

Brown, S. D., Duncan, J., Crabtree, D., Powell, D., Hudson, M. & Allan, J. L., 21 Apr 2020, In : Appetite. 152, 9 p., 104717.

Research output: Contribution to journalArticle

Who needs a stapling device for haemorrhoidectomy, if one has the radiofrequency device?

Sunny, A., Sellars, H., Ramsay, G., Polson, R. & Watson, A. J. M., Feb 2020, In : coloproctology. 42, p. 24-29 6 p.

Research output: Contribution to journalArticle

Open Access
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β-glucan is a major growth substrate for human gut bacteria related to Coprococcus eutactus

Alessi, A. M., Gray, V., Farquharson, F. M., Flores-López, A., Shaw, S., Stead, D., Wegmann, U., Shearman, C., Gasson, M., Collie-Duguid, E. SR., Flint, H. J. & Louis, P., Jun 2020, In : Environmental Microbiology. 22, 6, p. 2150-2164 15 p.

Research output: Contribution to journalArticle

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