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Research Output 2005 2019

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Article
2019

Identification of rumen microbial genes involved in pathways linked to appetite, growth and feed conversion efficiency in cattle

Lima, J., Auffret, M. D., Stewart, R. D., Dewhurst, R. J., Duthie, C-A., Snelling, T. J., Walker, A. W., Freeman, T. C., Watson, M. & Roehe, R., 3 Jul 2019, (Accepted/In press) In : Frontiers in Genetics.

Research output: Contribution to journalArticle

Open Access
Microbial Genes
Rumen
Appetite
Microbiota
Growth
1 Citation (Scopus)

Impact of carbohydrate substrate complexity on the diversity of the human colonic microbiota

Chung, W. S. F., Walker, A. W., Vermeiren, J., Sheridan, P. O., Bosscher, D., Garcia-Campayo, V., Parkhill, J., Flint, H. J. & Duncan, S. H., 1 Jan 2019, In : FEMS Microbiology Ecology. 95, 1, fiy201.

Research output: Contribution to journalArticle

Open Access
Inulin
Microbiota
carbohydrate
Carbohydrates
Bioreactors
2018
41 Citations (Scopus)
13 Downloads (Pure)

Assembly of 913 microbial genomes from metagenomic sequencing of the cow rumen

Stewart, R. D., Auffret, M. D., Warr, A., Wiser, A. H., Press, M. O., Langford, K. W., Liachko, I., Snelling, T. J., Dewhurst, R. J., Walker, A. W., Roehe, R. & Watson, M., 28 Feb 2018, In : Nature Communications. 9, p. 1-11 11 p., 870.

Research output: Contribution to journalArticle

Open Access
File
Microbial Genome
Metagenomics
sequencing
genome
Rumen
2 Citations (Scopus)
2 Downloads (Pure)

Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition

Drew, J. E., Reichardt, N., Williams, L. M., Mayer, C-D., Walker, A. W., Farquharson, A. J., Kastora, S., Farquharson, F., Milligan, G., Morrison, D. J., Preston, T., Flint, H. J. & Louis, P., 22 Oct 2018, In : Scientific Reports. 8, 15566.

Research output: Contribution to journalArticle

Open Access
File
Inulin
Cecum
Dietary Fiber
Obesity
Esters
3 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
Endotoxemia
Acute-Phase Proteins
High Fat Diet
Obesity
Diet
14 Citations (Scopus)
9 Downloads (Pure)

Gut microbiota trajectory in early life may predict development of celiac disease

Olivares, M., Walker, A. W., Capilla, A., Benitez-Paez, A., Palau, F., Parkhill, J., Castillejo, G. & Sanz, Y., 20 Feb 2018, In : Microbiome. 6, 36.

Research output: Contribution to journalArticle

Open Access
File
Celiac Disease
Microbiota
Gastrointestinal Microbiome
Bifidobacterium
Enterococcus
10 Citations (Scopus)
9 Downloads (Pure)

Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

Mukhopadhya, I., Morais, S., Laverde-Gomez, J., Sheridan, P. O., Walker, A. W., Kelly, W., Klieve, A. V., Ouwerkerk, D., Duncan, S. H., Louis, P., Koropatkin, N., Cockburn, D., Kibler, R., Cooper, P. J., Sandoval, C., Crost, E., Juge, N., Bayer, E. A. & Flint, H. J., Jan 2018, In : Environmental Microbiology. 20, p. 324-336 13 p.

Research output: Contribution to journalArticle

Open Access
File
Ruminococcus bromii
Ruminococcus
sporulation
Rumen
starch
3 Downloads (Pure)

Studying the microbiome and its complexities: an interview with Alan Walker

Walker, A. W., 1 Nov 2018, In : BMC Biology. 16, 1, 2 p., 134.

Research output: Contribution to journalArticle

Open Access
File
Microbiota
Nutrition
intestinal microorganisms
interviews
Interviews
6 Citations (Scopus)
5 Downloads (Pure)

The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

Kennedy, N. A., Lamb, C. A., Berry, S. H., Walker, A. W., Mansfield, J., Parkes, M., Simpkins, R., Tremelling, M., Nutland, S., UK IBD Genetics Consortium, Parkhill, J., Probert, C., Hold, G. L. & Lees, C. W., Mar 2018, In : Inflammatory Bowel Diseases. 24, 3, p. 583-592 10 p.

Research output: Contribution to journalArticle

Open Access
File
Gastrointestinal Diseases
Microbiota
Crohn Disease
Genotype
Dysbiosis
2017
14 Citations (Scopus)
7 Downloads (Pure)

A non-endoscopic device to sample the oesophageal microbiota: a case-control study

Elliott, D. R. F., Walker, A. W., O’Donovan, M., Parkhill, J. & Fitzgerald, R. C., Jan 2017, In : The Lancet Gastroenterology & Hepatology. 2, 1, p. 32-42 11 p.

Research output: Contribution to journalArticle

Open Access
File
Microbiota
Case-Control Studies
Adenocarcinoma
Equipment and Supplies
Barrett Esophagus
49 Citations (Scopus)

Bacterial microbiota of the upper respiratory tract and childhood asthma

Depner, M., Ege, M. J., Cox, M. J., Dwyer, S., Walker, A. W., Birzele, L. T., Genuneit, J., Horak, E., Braun-Fahrländer, C., Danielewicz, H., Maier, R. M., Moffatt, M. F., Cookson, W. O., Heederik, D., von Mutius, E. & Legatzki, A., 1 Mar 2017, In : Journal of Allergy and Clinical Immunology. 139, 3, p. 826–834 9 p.

Research output: Contribution to journalArticle

Microbiota
Moraxella
Respiratory System
Asthma
Nose
29 Citations (Scopus)
6 Downloads (Pure)

Dietary Uncoupling of Gut Microbiota and Energy Harvesting from Obesity and Glucose Tolerance in Mice

Dalby, M. J., Ross, A. W., Walker, A. W. & Morgan, P. J., 7 Nov 2017, In : Cell Reports. 21, 6, p. 1521-1533 13 p.

Research output: Contribution to journalArticle

Open Access
File
Energy harvesting
High Fat Diet
Nutrition
Obesity
Diet
95 Citations (Scopus)
22 Downloads (Pure)

Shotgun metagenomics, from sampling to analysis

Quince, C., Walker, A. W., Simpson, J. T., Loman, N. J. & Segata, N., 12 Sep 2017, In : Nature Biotechnology. 35, 9, p. 833-844 12 p.

Research output: Contribution to journalArticle

Open Access
File
Metagenomics
Firearms
Cataloging
Health
Sampling
1 Citation (Scopus)
3 Downloads (Pure)

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

Kannan, Y., Entwistle, L. J., Pelly, V. S., Perez-Lloret, J., Walker, A. W., Ley, S. C. & Wilson, M. S., 31 Jul 2017, In : PLoS Pathogens. 13, 7, 21 p., e1006536.

Research output: Contribution to journalArticle

Open Access
File
Nematospiroides dubius
Immunity
Infection
Leukocyte Chemotaxis
Receptors, Tumor Necrosis Factor, Type I
2016
8 Citations (Scopus)
4 Downloads (Pure)

Assessment of the influence of intrinsic environmental and geographical factors on the bacterial ecology of pit latrines

Torondel, B., Ensink, J. H. J., Gundogdu, O., Ijaz, U. Z., Parkhill, J., Abdelahi, F., Nguyen, V-A., Sudgen, S., Gibson, W., Walker, A. W. & Quince, C., Mar 2016, In : Microbial Biotechnology. 9, 2, p. 209-223 15 p.

Research output: Contribution to journalArticle

Open Access
File
Toilet Facilities
Ecology
Chemical analysis
Decomposition
Sanitation
14 Citations (Scopus)
5 Downloads (Pure)

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal Colon

Bernardo, D., Durant, L., Mann, E. R., Bassity, E., Montalvillo, E., Man, R., Vora, R., Reddi, D., Bayiroglu, F., Fernández-Salazar, L., English, N. R., Peake, S. T. C., Landy, J., Lee, G. H., Malietzis, G., Siaw, Y. H., Murugananthan, A. U., Hendy, P., Sánchez-Recio, E., Phillips, R. K. S. & 10 othersGarrote, J. A., Scott, P., Parkhill, J., Paulsen, M., Hart, A. L., Al-Hassi, H. O., Arranz, E., Walker, A. W., Carding, S. R. & Knight, S. C., Jan 2016, In : CMGH Cellular and Molecular Gastroenterology and Hepatology. 2, 1, p. 22-39.e5 23 p.

Research output: Contribution to journalArticle

Open Access
File
CCR Receptors
Dendritic Cells
Colon
Phenotype
Microbiota
1 Citation (Scopus)
14 Citations (Scopus)
5 Downloads (Pure)

Individual-specific changes in the human gut microbiota after challenge with enterotoxigenic Escherichia coli and subsequent ciprofloxacin treatment

Pop, M., Paulson, J. N., Chakraborty, S., Astrovskaya, I., Lindsay, B. R., Li, S., Corrada Bravo, H., Harro, C., Parkhill, J., Walker, A. W., Walker, R. I., Sack, D. A. & Stine, O. C., 8 Jun 2016, In : BMC Genomics. 17, p. 1-11 11 p., 440.

Research output: Contribution to journalArticle

Open Access
File
Enterotoxigenic Escherichia coli
Ciprofloxacin
Diarrhea
Microbiota
16S Ribosomal RNA
96 Citations (Scopus)
5 Downloads (Pure)

Modulation of the human gut microbiota by dietary fibres occurs at the species level

Chung, W. S. F., Walker, A. W., Louis, P., Parkhill, J., Vermeiren, J., Bosscher, D., Duncan, S. H. & Flint, H. J., 11 Jan 2016, In : BMC Biology. 14, 3.

Research output: Contribution to journalArticle

Open Access
File
Inulin
Dietary Fiber
intestinal microorganisms
Prebiotics
inulin
36 Citations (Scopus)
3 Downloads (Pure)

Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Green, L. E., Daniels, T. W. V., Carroll, M. P., Parkhill, J., Bruce, K. D. & van der Gast, C. J., May 2016, In : The ISME Journal. 10, 5, p. 1081-1091 11 p.

Research output: Contribution to journalArticle

Open Access
File
Microbiota
antibiotics
anti-infective agents
lungs
Lung
25 Citations (Scopus)
7 Downloads (Pure)

The Ecological Dynamics of Fecal Contamination and Salmonella Typhi and Salmonella Paratyphi A in Municipal Kathmandu Drinking Water

Karkey, A., Jombart, T., Walker, A. W., Thompson, C. N., Torres, A., Dongol, S., Tran Vu Thieu, N., Pham Thanh, D., Tran Thi Ngoc, D., Voong Vinh, P., Singer, A. C., Parkhill, J., Thwaites, G., Basnyat, B., Ferguson, N. & Baker, S., 6 Jan 2016, In : PLoS Neglected Tropical Diseases. 10, 1, p. 1-18 18 p., e0004346.

Research output: Contribution to journalArticle

Open Access
File
Salmonella paratyphi A
Salmonella typhi
Drinking Water
Typhoid Fever
Water
37 Citations (Scopus)
3 Downloads (Pure)

Wheat bran promotes enrichment within the human colonic microbiota of butyrate-producing bacteria that release ferulic acid

Duncan, S. H., Russell, W. R., Quartieri, A., Rossi, M., Parkhill, J., Walker, A. W. & Flint, H. J., 8 Jul 2016, In : Environmental Microbiology. 18, 7, p. 2214-2225 12 p.

Research output: Contribution to journalArticle

Open Access
File
ferulic acid
Butyrates
Microbiota
Dietary Fiber
wheat bran
2015
82 Citations (Scopus)
5 Downloads (Pure)

16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice

Walker, A. W., Martin, J. C., Scott, P., Parkhill, J., Flint, H. J. & Scott, K. P., 22 Jun 2015, In : Microbiome. 3, 26.

Research output: Contribution to journalArticle

Open Access
File
Bifidobacterium
rRNA Genes
Polymerase Chain Reaction
Feces
DNA
2 Citations (Scopus)
3 Downloads (Pure)

ARK: Aggregation of Reads by K-Means for Estimation of Bacterial Community Composition

Koslicki, D., Chatterjee, S., Shahrivar, D., Walker, A. W., Francis, S. C., Fraser, L. J., Vehkaperä, M., Lan, Y. & Corander, J., 23 Oct 2015, In : PloS ONE. 10, 10, e0140644.

Research output: Contribution to journalArticle

Open Access
File
bacterial communities
Agglomeration
Chemical analysis
Cluster Analysis
Compressed sensing
14 Citations (Scopus)
4 Downloads (Pure)

Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Hoffman, L. R., Carroll, M. P., Parkhill, J., Bruce, K. D. & van der Gast, C. J., Jul 2015, In : Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 14, 4, p. 464-467 4 p.

Research output: Contribution to journalArticle

Open Access
File
Sputum
Microbiota
rRNA Genes
Practice Guidelines
Cystic Fibrosis
30 Citations (Scopus)
324 Downloads (Pure)

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation

Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E., Walker, A. W., Stolarczyk, E., Ammoscato, F., Goldberg, R., Scott, P., Canavan, J. B., Perucha, E., Garrido-Mesa, N., Irving, P. M., Sanderson, J. D., Hayee, B., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., Aug 2015, In : Gastroenterology. 149, 2, p. 456-467 12 p.

Research output: Contribution to journalArticle

Open Access
File
Interleukin-6
Lymphocytes
Cytokines
Inflammation
Colon
11 Citations (Scopus)
4 Downloads (Pure)

Microbiota that affect risk for shigellosis in children in low-income countries

Lindsay, B., Oundo, J., Hossain, M. A., Antonio, M., Tamboura, B., Walker, A. W., Paulson, J. N., Parkhill, J., Omore, R., Faruque, A. S. G., Das, S. K., Ikumapayi, U. N., Adeyemi, M., Sanogo, D., Saha, D., Sow, S., Farag, T. H., Nasrin, D., Li, S., Panchalingam, S. & 8 othersLevine, M. M., Kotloff, K., Magder, L. S., Hungerford, L., Sommerfelt, H., Pop, M., Nataro, J. P. & Stine, O. C., Feb 2015, In : Emerging Infectious Diseases. 21, 2, p. 242-250 9 p.

Research output: Contribution to journalArticle

Open Access
File
Bacillary Dysentery
Shigella
Microbiota
Diarrhea
Lactobacillus
131 Citations (Scopus)
4 Downloads (Pure)

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

Zaiss, M. M., Rapin, A., Lebon, L., Dubey, L. K., Mosconi, I., Sarter, K., Piersigilli, A., Menin, L., Walker, A. W., Rougemont, J., Paerewijck, O., Geldhof, P., McCoy, K. D., Macpherson, A. J., Croese, J., Giacomin, P. R., Loukas, A., Junt, T., Marsland, B. J. & Harris, N. L., 17 Nov 2015, In : Immunity. 43, 5, p. 998-1010 13 p.

Research output: Contribution to journalArticle

Open Access
File
Helminths
Inflammation
Nematospiroides dubius
Microbiota
Anti-Inflammatory Agents
38 Citations (Scopus)

TLR Signaling Modulates Side Effects of Anticancer Therapy in the Small Intestine

Frank, M., Hennenberg, E. M., Eyking, A., Rünzi, M., Gerken, G., Scott, P., Parkhill, J., Walker, A. W. & Cario, E., 15 Feb 2015, In : The Journal of Immunology. 194, 4, p. 1983-1995 13 p.

Research output: Contribution to journalArticle

Small Intestine
Mucositis
Drug Therapy
Glycoproteins
Xenobiotics
24 Citations (Scopus)
27 Downloads (Pure)

Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis

Landy, J., Walker, A. W., Li, J. V., Al-Hassi, H. O., Ronde, E., English, N. R., Mann, E. R., Bernardo, D., McLaughlin, S. D., Parkhill, J., Ciclitira, P. J., Clark, S. K., Knight, S. C. & Hart, A. L., 12 Aug 2015, In : Scientific Reports. 5, 10 p., 12955.

Research output: Contribution to journalArticle

Open Access
File
Pouchitis
Microbiota
Clostridium Infections
Fecal Microbiota Transplantation
Mucosal Immunity
2014
8 Citations (Scopus)

Adding genomic 'foliage' to the tree of life

Walker, A., Feb 2014, In : Nature Reviews Microbiology. 12, 2, 78.

Research output: Contribution to journalArticle

Metagenomics
Ribosomal RNA
Surveys and Questionnaires
80 Citations (Scopus)
4 Downloads (Pure)

Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition

Pop, M., Walker, A. W., Paulson, J., Lindsay, B., Antonio, M., Hossain, M. A., Oundo, J., Tamboura, B., Mai, V., Astrovskaya, I., Bravo, H., Rance, R., Stares, M., Levine, M. M., Panchalingam, S., Kotloff, K., Ikumapayi, U. N., Ebruke, C., Adeyemi, M., Ahmed, D. & 15 othersAhmed, F., Alam, M., Amin, R., Siddiqui, S., Ochieng, J. B., Ouma, E., Juma, J., Mailu, E., Omore, R., Morris, J. G., Breiman, R. F., Saha, D., Parkhill, J., Nataro, J. P. & Stine, O. C., 27 Jun 2014, In : Genome Biology. 15, 6, R76.

Research output: Contribution to journalArticle

Open Access
File
intestinal microorganisms
Diarrhea
diarrhea
income
Microbiota
781 Citations (Scopus)
5 Downloads (Pure)

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Salter, S. J., Cox, M. J., Turek, E. M., Calus, S. T., Cookson, W. O., Moffatt, M. F., Turner, P., Parkhill, J., Loman, N. J. & Walker, A. W., 12 Nov 2014, In : BMC Biology. 12, 1, 87.

Research output: Contribution to journalArticle

Open Access
File
Metagenomics
Microbiota
rRNA Genes
Biomass
Contamination
113 Citations (Scopus)
3 Downloads (Pure)

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing

Kennedy, N. A., Walker, A. W., Berry, S. H., Duncan, S. H., Farquarson, F. M., Louis, P., Thomson, J. M., Satsangi, J., Flint, H. J., Parkhill, J., Lees, C. W., Hold, G. L. & UK IBD Genetics Consortium, 24 Feb 2014, In : PloS ONE. 9, 2, e88982.

Research output: Contribution to journalArticle

Open Access
File
Bacterial Structures
rRNA Genes
intestinal microorganisms
bacterial communities
Genes
20 Citations (Scopus)
3 Downloads (Pure)

Time between Collection and Storage Significantly Influences Bacterial Sequence Composition in Sputum Samples from Cystic Fibrosis Respiratory Infections

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Hafiz, T., Hoffman, L. R., Carroll, M. P., Parkhill, J., Bruce, K. D. & van der Gast, C. J., Aug 2014, In : Journal of Clinical Microbiology. 52, 8, p. 3011-3016 6 p.

Research output: Contribution to journalArticle

Open Access
File
Sputum
Cystic Fibrosis
Respiratory Tract Infections
Freezing
Microbiology
2013

Deep-sea striving

Walker, A., Jun 2013, In : Nature Reviews Microbiology. 11, 6, 364.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice

Clare, S., John, V., Walker, A. W., Hill, J. L., Abreu-Goodger, C., Hale, C., Goulding, D., Lawley, T. D., Mastroeni, P., Frankel, G., Enright, A. J., Vigorito, E. & Dougan, G., Mar 2013, In : Infection and Immunity. 81, 3, p. 723-732 10 p.

Research output: Contribution to journalArticle

Citrobacter rodentium
MicroRNAs
Infection
Germinal Center
Humoral Immunity
33 Citations (Scopus)

Fighting obesity with bacteria

Walker, A. W. & Parkhill, J., 6 Sep 2013, In : Science. 341, 6150, p. 1069-1070 2 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
3 Downloads (Pure)

Patent human infections with the whipworm, Trichuris trichiura, are not associated with alterations in the faecal microbiota

Cooper, P., Walker, A. W., Reyes, J., Chico, M., Salter, S. J., Vaca, M. & Parkhill, J., 4 Oct 2013, In : PloS ONE. 8, 10, 12 p., e76573.

Research output: Contribution to journalArticle

Open Access
File
Trichuris trichiura
Trichuris
Anthelmintics
Microbiota
patents
223 Citations (Scopus)
54 Downloads (Pure)

Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions

Adler, C. J., Dobney, K., Weyrich, L. S., Kaidonis, J., Walker, A. W., Haak, W., Bradshaw, C. J. A., Townsend, G., Sołtysiak, A., Alt, K. W., Parkhill, J. & Cooper, A., Apr 2013, In : Nature Genetics. 45, 4, p. 450-455 6 p.

Research output: Contribution to journalArticle

Open Access
File
Dental Plaque
Microbiota
Agriculture
Mouth Diseases
Dental Calculus
13 Citations (Scopus)

Survey of Culture, GoldenGate Assay, Universal Biosensor Assay, and 16S rRNA Gene Sequencing as Alternative Methods of Bacterial Pathogen Detection

Lindsay, B., Pop, M., Antonio, M., Walker, A. W., Mai, V., Ahmed, D., Oundo, J., Tamboura, B., Panchalingam, S., Levine, M. M., Kotloff, K., Li, S., Magder, L. S., Paulson, J. N., Liu, B., Ikumapayi, U., Ebruke, C., Dione, M., Adeyemi, M., Rance, R. & 32 othersStares, M. D., Ukhanova, M., Barnes, B., Lewis, I., Ahmed, F., Alam, M. T., Amin, R., Siddiqui, S., Ochieng, J. B., Ouma, E., Juma, J., Mailu, E., Omore, R., O'Reilly, C. E., Hannis, J., Manalili, S., Deleon, J., Yasuda, I., Blyn, L., Ranken, R., Li, F., Housley, R., Ecker, D. J., Hossain, M. A., Breiman, R. F., Morris, J. G., McDaniel, T. K., Parkhill, J., Saha, D., Sampath, R., Stine, O. C. & Nataro, J. P., Oct 2013, In : Journal of Clinical Microbiology. 51, 10, p. 3263-3269 7 p.

Research output: Contribution to journalArticle

Biosensing Techniques
rRNA Genes
Enterotoxigenic Escherichia coli
Enteropathogenic Escherichia coli
Shigella
2012
19 Citations (Scopus)
3 Downloads (Pure)

Bayesian estimation of bacterial community composition from 454 sequencing data

Cheng, L., Walker, A. W. & Corander, J., Jul 2012, In : Nucleic Acids Research. 40, 12, p. 5240-5249 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cluster Analysis
Statistical Models
rRNA Genes
Polymerase Chain Reaction
11 Citations (Scopus)

Fibrinogen-binding and platelet-aggregation activities of a Lactobacillus salivarius septicaemia isolate are mediated by a novel fibrinogen-binding protein

Collins, J., van Pijkeren, J-P., Svensson, L., Claesson, M. J., Sturme, M., Li, Y., Cooney, J. C., van Sinderen, D., Walker, A. W., Parkhill, J., Shannon, O. & O'Toole, P. W., Sep 2012, In : Molecular Microbiology. 85, 5, p. 862-877 16 p.

Research output: Contribution to journalArticle

Platelet Aggregation
Fibrinogen
Sepsis
Carrier Proteins
Probiotics
158 Citations (Scopus)

Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae

Stecher, B., Denzler, R., Maier, L., Bernet, F., Sanders, M. J., Pickard, D. J., Barthel, M., Westendorf, A. M., Krogfelt, K. A., Walker, A. W., Ackermann, M., Dobrindt, U., Thomson, N. R. & Hardt, W-D., 24 Jan 2012, In : PNAS. 109, 4, p. 1269-1274 6 p.

Research output: Contribution to journalArticle

Horizontal Gene Transfer
Enterobacteriaceae
Inflammation
Foster Home Care
Bacteriocin Plasmids
315 Citations (Scopus)
4 Downloads (Pure)

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice

Lawley, T. D., Clare, S., Walker, A. W., Stares, M. D., Connor, T. R., Raisen, C., Goulding, D., Rad, R., Schreiber, F., Brandt, C., Deakin, L. J., Pickard, D. J., Duncan, S. H., Flint, H. J., Clark, T. G., Parkhill, J. & Dougan, G., 25 Oct 2012, In : PLoS Pathogens. 8, 10, 14 p., e1002995.

Research output: Contribution to journalArticle

Open Access
File
189 Citations (Scopus)

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells

Powell, N., Walker, A. W., Stolarczyk, E., Canavan, J. B., Gökmen, M. R., Marks, E., Jackson, I., Hashim, A., Curtis, M. A., Jenner, R. G., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 19 Oct 2012, In : Immunity. 37, 4, p. 674-684 11 p.

Research output: Contribution to journalArticle

Interleukin-7 Receptors
Lymphocytes
Inflammation
Colitis
Ulcerative Colitis
11 Citations (Scopus)

Welcome to the plasmidome

Walker, A., Jun 2012, In : Nature Reviews Microbiology. 10, 6, p. 379 1 p.

Research output: Contribution to journalArticle

Metagenomics
Rumen
Plasmids
Genome
2011
670 Citations (Scopus)

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

Walker, A. W., Ince, J., Duncan, S. H., Webster, L., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., Louis, P., McIntosh, F., Johnstone, A. M., Lobley, G. E., Parkhill, J. & Flint, H. J., Feb 2011, In : The ISME Journal. 5, 2, p. 220-230 11 p.

Research output: Contribution to journalArticle

316 Citations (Scopus)
4 Downloads (Pure)

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

Walker, A. W., Sanderson, J. D., Churcher, C., Parkes, G. C., Hudspith, B. N., Rayment, N., Brostoff, J., Parkhill, J., Dougan, G. & Petrovska, L., 10 Jan 2011, In : BioMed Central Microbiology. 11, 12 p., 7.

Research output: Contribution to journalArticle

Open Access
File
Dysbiosis
Microbiota
Inflammatory Bowel Diseases
Crohn Disease
Intestines
132 Citations (Scopus)
3 Downloads (Pure)

Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

van der Gast, C. J., Walker, A. W., Stressmann, F. A., Rogers, G. B., Scott, P., Daniels, T. W., Carroll, M. P., Parkhill, J. & Bruce, K. D., May 2011, In : The ISME Journal. 5, 5, p. 780-791 12 p.

Research output: Contribution to journalArticle

Open Access
File
cystic fibrosis
bacterial communities
Cystic Fibrosis
partitioning
lungs