Alison Dorothy Murray

Professor

  • AB25 2ZD

  • 2695 Citations
1992 …2018
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Personal profile

Research Overview:

Professor Alison Murray is the Roland Sutton Chair of Radiology at the University of Aberdeen. She is Director of the Aberdeen Biomedical Imaging Centre www.abdn.ac.uk/ims/imaging/   Lilian Sutton Building, University of Aberdeen. This houses the 3T research magnetic resonance imaging (MRI) scanner. Research MRI facilities are located within the acute NHS hospital and are immediately adjacent to the John Mallard Positron Emission Tomography (PET) Centre and the NHS Department of Nuclear Medicine, facilitating combined studies of brain structure and function.

She leads clinical brain imaging research in structural and functional brain imaging correlates of cognitive ageing and dementia and recent work includes MRI in the Aberdeen 1936 Birth Cohort, and MRI, regional cerebral blood flow SPECT and FDG PET in clinical trials of novel Tau Aggregation Inhibitor therapies in Alzheimer's disease.  Particular interests are the relative cotributions of vascular risk factors and subclinical Alzheimer's disease to cognitve ageing and contributors to conitive researve and resilience against dementia.  She is also involved in brain imaging research in other neurodegenerative and neurodevelopmental diseases, utilising quantitative assessment of brain volumes, disease burden and function. 

She has extensive clinical experience of brain imaging in dementia, being responsible for over 500 nuclear medicine brain regional cerebral blood flow SPECT studies per annum, receptor studies in movement disorder and, previously with colleagues in Nuclear Medicine, development of national clinical positron emission service across Scotland.

She is a founding member and executive member of the Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) www.sinapse.ac.uk  a successful brain imaging pooling initiative funded by the Scottish Funding Council and participating universities to develop state of the art brain imaging research training and resources across Scotland.

Research Keywords:

medicine; neuroradiology; normal cognitive ageing; dementia

Qualifications:

MB ChB (Hons), MRCP, FRCR, FRCP, PhD

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Research Output 1992 2018

2 Citations

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Sung, Y. J. , Winkler, T. W. , de Las Fuentes, L. , Bentley, A. R. , Brown, M. R. , Kraja, A. T. , Schwander, K. , Ntalla, I. , Guo, X. , Franceschini, N. , Lu, Y. , Cheng, C-Y. , Sim, X. , Vojinovic, D. , Marten, J. , Musani, S. K. , Li, C. , Feitosa, M. F. , Kilpeläinen, T. O. , Richard, M. A. & 31 others Noordam, R., Aslibekyan, S., Aschard, H., Bartz, T. M., Dorajoo, R., Liu, Y., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Warren, H. R., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Horimoto, A. R. V. R., Murray, A. D. & CHARGE Neurology Working Group 1 Mar 2018 In : American Journal of Human Genetics. 102, 3, p. 375-400 6 p.

Research output: Contribution to journalArticle

Smoking
Genome
Blood Pressure
Genome-Wide Association Study
Blood Vessels
1 Citations

A multi-modal MRI study of the central response to inflammation in rheumatoid arthritis

Schrepf, A., Kaplan, C. M., Ichesco, E., Larkin, T., Harte, S., Harris, R. E., Murray, A. D., Waiter, G. D., Clauw, D. J. & Basu, N. 8 Jun 2018 In : Nature communications. 9, p. 1-11 11 p., 2243

Research output: Contribution to journalArticle

Open Access
File
arthritis
Magnetic resonance imaging
Parietal Lobe
brain
Brain
1 Citations

Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): a questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS)

Navrady, L. B., Wolters, M. K., MacIntyre, D. J., Clarke, T-K., Campbell, A. I., Murray, A. D., Evans, K. L., Seckl, J., Haley, C., Milburn, K., Wardlaw, J. M., Porteous, D. J., Deary, I. J. & McIntosh, A. M. Feb 2018 In : International Journal of Epidemiology. 47, 1, p. 13-14G 2 p.

Research output: Contribution to journalArticle

Open Access
File
Aging of materials
Brain
Neurodegenerative diseases
Complex networks
Magnetic resonance
1 Citations

Epigenetic prediction of complex traits and death

McCartney, D. L. , Hillary, R. F. , Stevenson, A. J. , Ritchie, S. J. , Walker, R. M. , Zhang, Q. , Morris, S. W. , Bermingham, M. L. , Campbell, A. , Murray, A. D. , Whalley, H. C. , Gale, C. R. , Porteous, D. J. , Haley, C. S. , McRae, A. F. , Wray, N. R. , Visscher, P. M. , McIntosh, A. M. , Evans, K. L. , Deary, I. J. & 1 others Marioni, R. E. 27 Sep 2018 In : Genome Biology. 19, 136

Research output: Contribution to journalArticle

Open Access
File
methylation
DNA methylation
DNA Methylation
Epigenomics
epigenetics

Prizes

Fellow of the Royal Society of Edinburgh

Alison Dorothy Murray (Recipient), 26 Feb 2018

Prize: Election to learned society

Equipment

Radiochemistry
Technology
Cyclotrons
Diagnostic Imaging
Research