• 3051 Citations
1992 …2019
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Personal profile

Research Overview:

Professor Alison Murray is the Roland Sutton Chair of Radiology at the University of Aberdeen. She is Director of the Aberdeen Biomedical Imaging Centre www.abdn.ac.uk/ims/imaging/   Lilian Sutton Building, University of Aberdeen. This houses the 3T research magnetic resonance imaging (MRI) scanner. Research MRI facilities are located within the acute NHS hospital and are immediately adjacent to the John Mallard Positron Emission Tomography (PET) Centre and the NHS Department of Nuclear Medicine, facilitating combined studies of brain structure and function.

She leads clinical brain imaging research in structural and functional brain imaging correlates of cognitive ageing and dementia and recent work includes MRI in the Aberdeen 1936 Birth Cohort, and MRI, regional cerebral blood flow SPECT and FDG PET in clinical trials of novel Tau Aggregation Inhibitor therapies in Alzheimer's disease.  Particular interests are the relative cotributions of vascular risk factors and subclinical Alzheimer's disease to cognitve ageing and contributors to conitive researve and resilience against dementia.  She is also involved in brain imaging research in other neurodegenerative and neurodevelopmental diseases, utilising quantitative assessment of brain volumes, disease burden and function. 

She has extensive clinical experience of brain imaging in dementia, being responsible for over 500 nuclear medicine brain regional cerebral blood flow SPECT studies per annum, receptor studies in movement disorder and, previously with colleagues in Nuclear Medicine, development of national clinical positron emission service across Scotland.

She is a founding member and executive member of the Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) www.sinapse.ac.uk  a successful brain imaging pooling initiative funded by the Scottish Funding Council and participating universities to develop state of the art brain imaging research training and resources across Scotland.

Research Keywords:

medicine; neuroradiology; normal cognitive ageing; dementia

Qualifications:

MB ChB (Hons), MRCP, FRCR, FRCP, PhD

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Research Output 1992 2019

3 Downloads (Pure)

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O. K. L., Zhang, Q., McRae, A. F., Walker, R. M., Morris, S. W., Redmond, P., Campbell, A., Murray, A. D., Porteous, D. J., Evans, K. L., McIntosh, A. M., Deary, I. J. & Marioni, R. E., 6 Mar 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Epigenomics
Body Mass Index
Parturition
Health
1 Downloads (Pure)
Open Access
File
Aging of materials
Brain
Neurodegenerative diseases
Complex networks
Magnetic resonance

Functional and structural magnetic resonance imaging correlates of fatigue in patients with rheumatoid arthritis

Basu, N., Kaplan, C. M., Ichesco, E., Larkin, T., Schrepf, A., Murray, A. D., Clauw, D. J., Waiter, G. D. & Harris, R. E., 28 Apr 2019, In : Rheumatology.

Research output: Contribution to journalArticle

Fatigue
Rheumatoid Arthritis
Magnetic Resonance Imaging
Brain
Putamen

Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability

Lorgen-Ritchie, M., Murray, A. D., Ferguson-Smith, A. C., Richards, M., Horgan, G. W., Phillips, L. H., Hoad, G., Gall, I., Harrison, K., McNeill, G., Ito, M. & Haggarty, P., 1 Feb 2019, In : PloS ONE. 14, 2, 15 p., e0211799.

Research output: Contribution to journalArticle

Open Access
File
snRNP Core Proteins
Aptitude
Methylation
genomic imprinting
methylation

Insulin resistance: Genetic associations with depression and cognition in population based cohorts

Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., 6 Apr 2019, In : Experimental Neurology. 316, p. 20-26 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cognition
Insulin Resistance
Depression
Population
Intelligence

Prizes

Fellow of the Royal Society of Edinburgh

Alison Dorothy Murray (Recipient), 26 Feb 2018

Prize: Election to learned society

Equipment

Radiochemistry
Technology
Cyclotrons
Diagnostic Imaging
Research