• 1307 Citations
19982020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Standardization of preclinical PET/CT imaging to improve quantitative accuracy, precision and reproducibility: a multi-center study

McDougald, W., Vanhove, C., Lehnert, A., Lewellen, B., Wright, J., Mingarelli, M., Corral, C. A., Schneider, J., Plein, S., Newby, D., Welch, A., Miyaoka, R., Vandenberghe, S. & Tavares, A. A. S., 1 Mar 2020, In : Journal of Nuclear Medicine. 61, 3, p. 461-468 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)
2018

Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A., Elmore, C. S., Dawson, D., Sharma, P. & Zanda, M., 30 Jul 2018, In : Contrast Media & Molecular Imaging. 2018, 10 p., 3064751.

Research output: Contribution to journalArticle

Open Access
File
10 Downloads (Pure)
2017

Characterization of viability, scarring and hibernation of the myocardium supplied by epicardial coronary arteries with low flow grades

Al-Mohammad, A., Norton, M. Y., Welch, A. E. & Walton, S., 1 Aug 2017, In : Nuclear Medicine Communications. 38, 8, p. 657-665 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A. E., Elmore, C. S., Sharma, P. & Zanda, M., 1 Feb 2017, In : Bioorganic & Medicinal Chemistry. 25, 3, p. 963-976 14 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
9 Downloads (Pure)

Gated metabolic myocardial imaging, a surrogate for dual perfusion-metabolism imaging by positron emission tomography

AlMohammad, A., Norton, M. Y., Welch, A. E., Sharp, P. F. & Walton, S., 28 Jul 2017, In : Open Heart. 4, 2, p. 1-6 6 p., e000581.

Research output: Contribution to journalArticle

Open Access
File
8 Downloads (Pure)
2016

Neuronal human BACE1 knock-in induces systemic diabetes in mice

Plucinska, K., Dekeryte, R., Koss, D., Shearer, K., Mody, N., Whitfield, P. D., Doherty, M. K., Mingarelli, M., Welch, A., Riedel, G., Delibegovic, M. & Platt, B., Jul 2016, In : Diabetologia. 59, 7, p. 1513-1523 11 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
13 Downloads (Pure)
2014

Comparison of fluorodeoxyglucose uptake in symptomatic carotid artery and stable femoral artery plaques

Shaikh, S., Welch, A., Ramalingam, S. L., Murray, A., Wilson, H. M., McKiddie, F. & Brittenden, J., Mar 2014, In : British Journal of Surgery. 101, 3, p. 363-370 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Glucose uptake by the brain on chronic high-protein weight-loss diets with either moderate or low amounts of carbohydrate

Lobley, G. E., Johnstone, A. M., Fyfe, C., Horgan, G. W., Holtrop, G., Bremner, D. M., Broom, I., Schweiger, L. & Welch, A., Feb 2014, In : British Journal of Nutrition. 111, 4, p. 586-597 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
19 Downloads (Pure)

Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas

Bain, G. H., Collie-Duguid, E., Murray, G. I., Gilbert, F. J., Denison, A., McKiddie, F., Ahearn, T., Fleming, I., Leeds, J., Phull, P., Park, K., Nanthakumaran, S., Grabsch, H. I., Tan, P., Welch, A., Schweiger, L., Dahle-Smith, A., Urquhart, G., Finegan, M., Matula, K. M. & 1 others, Petty, R. D., 18 Mar 2014, In : British Journal of Cancer. 110, 6, p. 1525-1534 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2013

18F-barbiturates are PET tracers with diagnostic potential in Alzheimer's disease

Calamai, E., Dall'Angelo, S., Koss, D., Domarkas, J., McCarthy, T. J., Mingarelli, M., Riedel, G., Schweiger, L. F., Welch, A. E., Platt, B. & Zanda, M., 2013, In : Chemical Communications. 49, 8, p. 792-794 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Mapping Changes in Mouse Brain Metabolism with PET/CT

Welch, A., Mingarelli, M., Riedel, G. & Platt, B., 1 Nov 2013, In : Journal of Nuclear Medicine. 54, 11, p. 1946-1953 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis

Owen, C., Czopek, A., Agouni, A., Grant, L., Judson, R., Lees, E. K., McIlroy, G. D., Göransson, O., Welch, A., Bence, K. K., Kahn, B. B., Neel, B. G., Mody, N. & Delibegovic, M., 28 Feb 2012, In : PloS ONE. 7, 2, 15 p., e32700.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
7 Downloads (Pure)
2011

Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1

Platt, B., Drever, B., Koss, D., Stoppelkamp, S., Jyoti, A., Plano, A., Utan, A., Merrick, G., Ryan, D., Melis, V., Wan, H., Mingarelli, M., Porcu, E., Scrocchi, L., Welch, A. & Riedel, G., 11 Nov 2011, In : PloS ONE. 6, 11, 13 p., e27068.

Research output: Contribution to journalArticle

Open Access
File
74 Citations (Scopus)
7 Downloads (Pure)
Open Access
File
23 Citations (Scopus)
7 Downloads (Pure)
2010

An enzymatic route to 5-deoxy-5-[18F]fluoro-D-ribose, a [18F]-fluorinated sugar for PET imaging

Onega, M., Domarkas, J., Deng, H., Schweiger, L. F., Smith, T. A. D., Welch, A., Plisson, C., Gee, A. D. & O'Hagan, D., 2010, In : Chemical Communications. 46, 1, p. 139-141 3 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

F-18-FDG and C-11-choline positron emission tomography in human esophago-gastric cancer: prediction of response to therapy

Suttie, S., McAteer, D., Sheehan, M., Nicolson, M., Schweiger, L., Hammonds, S., Smith, T., Welch, A. & Park, K., Apr 2010, In : World Journal of Oncology. 1, 2, p. 66-77 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Downloads (Pure)
2007

[Methyl-3H]-choline incorporation into MCF-7 Cells: Correlation with Proliferation-Choline Kinase and Phospholipase D Assay

Al-Saeedi, F., Smith, T. & Welch, A., 2007, In : Anticancer Research. 27, 2, p. 901-906 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Decreased [18F]fluoro-2-deoxy-d-glucose incorporation and increased glucose transport are associated with resistance to 5FU in MCF7 cells in vitro

Smith, T. A. D., Sharma, R. I., Wang, W. G., Welch, A., Schweiger, L. F. & Collie-Duguid, E. S. R., Nov 2007, In : Nuclear Medicine and Biology. 34, 8, p. 955-960 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Monitoring primary breast cancer throughout chemotherapy using FDG-PET

McDermott, G. M., Welch, A., Staff, R. T., Gilbert, F. J., Schweiger, L. F., Semple, S. I. K., Smith, T. A. D., Hutcheon, A. W., Miller, I. D., Smith, I. C. & Heys, S. D., Mar 2007, In : Breast Cancer Research and Treatment. 102, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Physical health-related quality of life predicts stroke in the EPIC-Norfolk

Myint, P. K., Surtees, P. G., Wainwright, N. W. J., Luben, R. N., Welch, A. A., Bingham, S. A., Wareham, N. J. & Khaw, K-T., 11 Dec 2007, In : Neurology. 69, 24, p. 2243-2248 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Synthesis of (E)-2,3´,4,5´-Tetramethoxy[2-11C]stilbene

Schweiger, L. F., Craib, S. A. P., Welch, A. & Smith, T. A. D., Nov 2007, In : Journal of Labelled Compounds and Radiopharmaceuticals. 50, 13, p. 1206-1210 5 p.

Research output: Contribution to journalArticle

2006

Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administration

Semple, S. I. K., Staff, R. T., Heys, S. D., Redpath, T. W., Welch, A., Ahearn, T. S., Hutcheon, A. W. & Gilbert, F. J., Sep 2006, In : Annals of Oncology. 17, p. 1393-1398 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Development of a Monte Carlo simulation for APO-based PET detectors using a continuous scintillating crystal

Clowes, P., McCallum, S. & Welch, A., Oct 2006, In : IEEE Transactions on Nuclear Science. 53, 5, p. 2563-2569 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2005

[methyl-3H]Choline incorporation into MCF7 tumour cells: correlation with proliferation

Al-Saeedi, F., Welch, A. & Smith, T. A. D., Jun 2005, In : European Journal of Nuclear Medicine and Molecular Imaging. 32, 6, p. 660-667 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

A four-layer attenuation compensated PET detector based on APD arrays without discrete crystal elements

McCallum, S. J., Clowes, P. & Welch, A., Sep 2005, In : Physics in Medicine and Biology. 50, 17, p. 4187-4207 20 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Respiratory function and self-reported functional health: EPIC-Norfolk population study

Myint, P. K., Luben, R. N., Surtees, P. G., Wainwright, N. W. J., Welch, A. A., Bingham, S. A., Wareham, N. J., Day, N. E. & Khaw, K-T., Sep 2005, In : European Respiratory Journal. 26, 3, p. 494-502 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2004

The correlation between FDG PET and the vascular characteristic of breast tumours measured using dynamic contrast enhanced MRI

Semple, S. I. K., Staff, R. T., Gilbert, F. J., Redpath, T. W., Ahearn, T. S., Welch, A. & Heys, S. D., Aug 2004, In : European Journal of Nuclear Medicine and Molecular Imaging. 31, Suppl., p. S231 1 p.

Research output: Contribution to journalArticle

The relationship between vascular and metabolic characteristics of primary breast tumours

Semple, S. I. K., Gilbert, F. J., Redpath, T. W., Staff, R. T., Ahearn, T. S., Welch, A., Heys, S. D., Hutcheon, A. W., Smyth, E. H. & Chaturvedi, S., Nov 2004, In : European Radiology. 14, 11, p. 2038-2045 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2003

Accurate Attenuation Correction in PET using Short Transmission Scans and Consistency Information

Welch, A., Hallett, W., Marsden, P. & Bromiley, A., Jun 2003, In : IEEE Transactions on Nuclear Science. 50, 3, p. 427-432 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Correlation of MRI/PET rim enhancement in breast cancer: a delivery related phenomenon with therapy implications?

Semple, S. I. K., Gilbert, F. J., Redpath, T. W., Ahearn, T. S., Welch, A., Hutcheon, A. W., Heys, S. D., Smyth, E. H., Miller, I. D. & Smith, I. C., Dec 2003, In : The Lancet Oncology. 4, 12, p. 759-759

Research output: Contribution to journalArticle

7 Citations (Scopus)

Detection of scarred and viable myocardium using a new magnetic resonance imaging technique: Blood Oxygen Level Dependent (BOLD) MRI

Egred, M., Al-Mohammad, A., Waiter, G. D., Redpath, T. W., Semple, S. I. K., Norton, M. Y., Welch, A. & Walton, S., Jul 2003, In : Heart. 89, 7, p. 738-744 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Radiosynthesis of [N-methyl-C-11]methylene blue

Schweiger, L. F., Craib, S. A. P., Welch, A. & Sharp, P. F., 2003, In : Journal of Labelled Compounds and Radiopharmaceuticals. 46, p. 1221-1228 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2002

[F-18]fluorodeoxy-D-glucose positron emission tomography may predict the pathological response of breast cancer to primary chemotherapy

Gardiner, E., Ogston, K. N., Smith, I. C., Welch, A., Sharp, P. F., Hutcheon, A. W., Ah-See, A. K., Eremin, O. & Heys, S. D., 2002, In : British Journal of Surgery. 88, p. 761-767 6 p.

Research output: Contribution to journalArticle

A digital phantom of the axilla based on the visible human project data set

McCallum, S. J., Welch, A. & Baker, L., 2002, In : IEEE Transactions on Nuclear Science. 48, p. 1418-1422 4 p.

Research output: Contribution to journalArticle

Attenuation correction in PET using consistency conditions and a three-dimensional template

Bromiley, A., Welch, A., Chilcott, F. I., Waiker, S., McCallum, S. J., Dodd, M. G., Craib, S. A. P., Schweiger, L. F. & Sharp, P. F., 2002, In : IEEE Transactions on Nuclear Science. 48, p. 1371-1377 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Blood oxygen level dependent (BOLD) MRI for the detection of scarred and viable myocardium, a PET comparative study

Egred, M., Al-Mohammad, A., Waiter, G. D., Redpath, T. W., Semple, S., Welch, A., Norton, M. & Walton, S., 2002, In : European Heart Journal. 23, p. 305 1 p.

Research output: Contribution to journalArticle

Does the presence of hibernating myocardium in patients with impaired left ventricular contraction affect QT dispersion

Al Mohammad, A., Mahy, I. R., Buckley, A., Cargill, R. I., Norton, M. Y., Welch, A. & Walton, S., 2002, In : American Heart Journal. 141, p. 944-948 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2001

Dos the presence of hibernating myocardium in patients with impaired left ventricular contraction affect QT dispersion?

Al Mohammad, A., Mahy, I. R., Buckley, A., Cargill, R. I., Norton, M. Y., Welch, A. E. & Walton, S., 2001, In : American Heart Journal. 141, p. 944-948 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2000

A three-dimensional ray-driven attenuation, scatter and geometric response correction technique for SPECT in inhomogeneous media

Laurette, I., Zeng, G. L., Welch, A., Christian, P. E. & Gullberg, G. T., 2000, In : Physics in Medicine and Biology. 45, p. 3459-3480 22 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Language mapping in a left handed patient with glioma using H215O positron emission tomography

Malagoli, M., Murray, A. D., Venneri, A., Welch, A., Currie, D. G., Kaar, G. & Staff, R. T., 2000, In : Neuroimage. 11, 5, p. S321 1 p.

Research output: Contribution to journalArticle

Positron emission tomography using [F-18]-fluorodeoxy-D-glucose to predict the pathologic response of breast cancer to primary chemotherapy

Smith, I. C., Welch, A. E., Hutcheon, A. W., Miller, I. D., Payne, S., Chilcott, F., Waikar, S., Whitaker, T., Ah-See, A. K., Eremin, O., Heys, S. D., Gilbert, F. J. & Sharp, P. F., 2000, In : Journal of Clinical Oncology. 18, p. 1676-1688 13 p.

Research output: Contribution to journalArticle

382 Citations (Scopus)

Regional myocardial wall thickening assessed at rest by ECG gated F-18-FDG positron emission tomography and by magnetic resonance imaging

Waiter, G. D., Al-Mohammad, A., Norton, M. Y., Redpath, T. W., Welch, A. & Walton, S., 2000, In : Heart. 84, p. 332-333 2 p.

Research output: Contribution to journalArticle

1999

Can the surface electrocardiogram be used to predict myocardial viability?

Al-Mohammad, A., Norton, M. Y., Mahy, I. R., Patel, J. C., Welch, A. E., Mikecz, P. & Walton, S., 1999, In : Heart. 82, p. 663-667 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Comparison of three applications of ConTraSPECT

Laurette, I., Clackdoyle, R., Welch, A., Natterer, F. & Gullberg, G. T., 1999, In : IEEE Transactions on Nuclear Science. 46, p. 2146-2153 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

McAteer, D., Wallis, F., Couper, G., Norton, M., Welch, A., Bruce, D., Park, K., Nicholson, M., Gilbert, F. J. & Sharp, P. F., Jun 1999, In : British Journal of Radiology. 72, 858, p. 525-529 5 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Gated metabolic imaging: A single agent method in detecting hibernating myocardium

Al-Mohammad, A., Norton, M. Y., Mahy, I. R., Welch, A. E., Mikecz, P. & Walton, S., 1 May 1999, In : Heart. 81, SUPPL. 1

Research output: Contribution to journalArticle

1998

Attenuation correction in PET using consistency information

Welch, A., Campbell, C. & Clackdoyle, R., 1 Dec 1998, In : IEEE Transactions on Nuclear Science. 45, 6 PART 2, p. 3134-3141 8 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)