• 1030 Citations
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Research Output 2001 2019

  • 1030 Citations
  • 27 Article
  • 3 Poster
  • 2 Chapter
  • 1 Literature review
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Article
2019

Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

Donaldson, A. D. & Nieduszynski, C. A., 30 May 2019, In : Genome Biology. 20, 4 p., 111.

Research output: Contribution to journalArticle

Open Access
File
DNA Replication Timing
DNA replication
genome
Genome
DNA
1 Citation (Scopus)

Human RIF1-Protein Phosphatase 1 prevents degradation and breakage of nascent DNA on replication stalling

Garzón, J., Ursich, S., Lopes, M., Hiraga, S. & Donaldson, A. D., 28 May 2019, In : Cell Reports. 27, 9, p. 2558-2566 13 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
DNA Replication
Degradation
DNA
Genomic Instability
2018
6 Citations (Scopus)
5 Downloads (Pure)

Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks

Hiraga, S., Monerawela, C., Katou, Y., Shaw, S., Clark, K. R. M., Shirahige, K. & Donaldson, A. D., 1 Sep 2018, In : EMBO reports. 19, 9, p. 1-14 14 p., e46222.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycetales
Replication Origin
Hydroxyurea
Yeast
DNA Replication
3 Downloads (Pure)

Identification of Elg1 interaction partners and effects on post-replication chromatin re-formation

Gali, V. K., Dickerson, D., Katou, Y., Fujiki, K., Shirahige, K., Owen-Hughes, T., Kubota, T. & Donaldson, A. D., 12 Nov 2018, In : PLoS Genetics. 14, 11, e1007783.

Research output: Contribution to journalArticle

Open Access
File
DNA replication
DNA Replication
Chromatin
chromatin
Proliferating Cell Nuclear Antigen
6 Citations (Scopus)
5 Downloads (Pure)

Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast

Kedziora, S., Gali, V. K., Wilson, R. H. C., Clark, K. R. M., Nieduszynski, C. A., Hiraga, S. & Donaldson, A. D., 4 May 2018, In : Nucleic Acids Research. 46, 8, p. 3993-4003 11 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Saccharomycetales
Telomere
Replication Origin
Telomere Homeostasis
2017
35 Citations (Scopus)
5 Downloads (Pure)

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Hiraga, S., Ly, T., Garzon, J., Hořejší, Z., Ohkubo, Y., Endo, A., Obuse, C., Boulton, S. J., Lamond, A. I. & Donaldson, A. D., 1 Mar 2017, In : EMBO reports. 18, 3, p. 403-419 17 p., e201641983.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Replication Origin
Licensure
DNA Replication
Chemical activation
2015
29 Citations (Scopus)
5 Downloads (Pure)

Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation

Kubota, T., Katou, Y., Nakato, R., Shirahige, K. & Donaldson, A. D., 4 Aug 2015, In : Cell Reports. 12, 5, p. 774-787 14 p.

Research output: Contribution to journalArticle

Open Access
File
Proliferating Cell Nuclear Antigen
Unloading
Ligation
Genes
Genome
2014
17 Citations (Scopus)
4 Downloads (Pure)

At short telomeres Tel1 directs early replication and phosphorylates Rif1

Sridhar, A., Kedziora, S. M. & Donaldson, A. D., 16 Oct 2014, In : PLoS Genetics. 10, 10, e1004691.

Research output: Contribution to journalArticle

Open Access
File
telomeres
Telomere
proteomics
substrate
phosphorylation
109 Citations (Scopus)
34 Downloads (Pure)

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

Hiraga, S., Alvino, G. M., Chang, F., Lian, H., Sridhar, A., Kubota, T., Brewer, B. J., Weinreich, M., Raghuraman, M. K. & Donaldson, A. D., 15 Feb 2014, In : Genes & Development. 28, 4, p. 372-383 12 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
DNA Replication
Phosphorylation
Phosphotransferases
Saccharomycetales
2013
18 Citations (Scopus)
4 Downloads (Pure)

Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?

Kubota, T., Myung, J-K. & Donaldson, A. D., 15 Aug 2013, In : Cell Cycle. 12, 16, p. 2570-2579 10 p.

Research output: Contribution to journalArticle

Open Access
File
Replication Protein C
Genomic Instability
Proliferating Cell Nuclear Antigen
Saccharomycetales
Fungal Proteins
106 Citations (Scopus)

The Elg1 replication factor C-like complex functions in PCNA unloading during DNA replication

Kubota, T., Nishimura, K., Kanemaki, M. T. & Donaldson, A. D., 25 Apr 2013, In : Molecular Cell. 50, 2, p. 273-280 8 p.

Research output: Contribution to journalArticle

Replication Protein C
Proliferating Cell Nuclear Antigen
DNA Replication
Chromatin
Genomic Instability
2012
12 Citations (Scopus)

Quantitative proteomic analysis of yeast DNA replication proteins

Kubota, T., Stead, D. A., Hiraga, S., ten Have, S. & Donaldson, A. D., Jun 2012, In : Methods. 57, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle

DNA Replication
Proteomics
Yeast
Chromatin
Yeasts
16 Citations (Scopus)
3 Downloads (Pure)

TFIIIC Localizes Budding Yeast ETC Sites to the Nuclear Periphery

Hiraga, S., Botsios, S., Donze, D. & Donaldson, A. D., 15 Jul 2012, In : Molecular Biology of the Cell. 23, 14, p. 2741-2754 14 p.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycetales
Saccharomyces cerevisiae
transcription factor TFIIIC
Chromatin
RNA Polymerase III
2011
156 Citations (Scopus)

Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast

Mantiero, D., Mackenzie, A., Donaldson, A. D. & Zegerman, P., 2011, In : EMBO Journal. 30, 23, p. 4805-4814 10 p.

Research output: Contribution to journalArticle

Peptide Initiation Factors
Saccharomycetales
Cyclin-Dependent Kinases
S Phase
Yeast
37 Citations (Scopus)
4 Downloads (Pure)

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint

Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D., 1 Jul 2011, In : Molecular and Cellular Proteomics. 10, 7, M110 005561.

Research output: Contribution to journalArticle

Open Access
File
DNA Replication
Proteomics
Chromatin
Replication Protein C
DNA
52 Citations (Scopus)
4 Downloads (Pure)

The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation

Lian, H., Robertson, E. D., Hiraga, S., Alvino, G. M., Collingwood, D., McCune, H. J., Sridhar, A., Brewer, B. J., Raghuraman, M. K. & Donaldson, A. D., 15 May 2011, In : Molecular Biology of the Cell. 22, 10, p. 1753-1756 4 p.

Research output: Contribution to journalArticle

Open Access
File
Telomere
Acetylation
Histones
Genome Components
Replication Origin
2010
23 Citations (Scopus)
3 Downloads (Pure)

Early initiation of a replication origin tethered at the nuclear periphery

Ebrahimi, H., Robertson, E. D., Taddei, A., Gasser, S. M., Donaldson, A. D. & Hiraga, S-I., 23 Mar 2010, In : Journal of Cell Science. 123, p. 1015-1019

Research output: Contribution to journalArticle

Open Access
File
Replication Origin
Single-Cell Analysis
Saccharomycetales
S Phase
Isotopes
2008
25 Citations (Scopus)
6 Downloads (Pure)

Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning

Hiraga, S-I., Botsios, S. & Donaldson, A. D., 17 Nov 2008, In : Journal of Cell Biology. 183, 4, p. 641-651 11 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
2007
3 Downloads (Pure)

OriDB: a DNA replication origin database

Nieduszynski, C. A., Hiraga, S-I., Ak, P., Benham, C. J. & Donaldson, A. D., Jan 2007, In : Nucleic Acids Research. 35, Database Issue, p. D40-D46 7 p.

Research output: Contribution to journalArticle

Open Access
File
Replication Origin
DNA Replication
Databases
Chromosomes
Genome
2006
123 Citations (Scopus)

Genome-wide identification of replication origins in yeast by comparative genomics

Nieduszynski, C. A., Knox, Y. & Donaldson, A. D., Jul 2006, In : Genes & Development. 20, 14, p. 1874-1879 5 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
1 Downloads (Pure)

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time

Hiraga, S-I., Robertson, E. D. & Donaldson, A. D., Apr 2006, In : EMBO Journal. 25, 7, p. 1505-1514 9 p.

Research output: Contribution to journalArticle

File
2005
37 Citations (Scopus)

The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription

Nieduszynski, C. A., Blow, J. J. & Donaldson, A. D., Apr 2005, In : Nucleic Acids Research. 33, 8, p. 2410-2420 10 p.

Research output: Contribution to journalArticle

2003
7 Citations (Scopus)

DNA replication: telling time with microarrays

McCune, H. J. & Donaldson, A. D., 2003, In : Genome Biology. 4, 2

Research output: Contribution to journalArticle

2002
78 Citations (Scopus)

Ku complex controls the replication time of DNA in telomere regions

Cosgrove, A., Nieduszynski, C. A. & Donaldson, A. D., Oct 2002, In : Genes & Development. 16, 19, p. 2485-2490 5 p.

Research output: Contribution to journalArticle

2001
13 Citations (Scopus)

DNA replication: stable driving prevents fatal smashes

Donaldson, A. D. & Blow, J. J., 2001, In : Current Biology. 11, 23, p. R979-82

Research output: Contribution to journalArticle

Eukaryotic DNA Replication: from ORC to fork

Nieduszynski, C. A., Donaldson, A. D. & Blow, J. J., 2001, In : Genome Biology. 2, p. 4030.1-4030.3

Research output: Contribution to journalArticle