If you made any changes in Pure these will be visible here soon.

Research Output

  • 710 Citations
  • 46 Article
2019

Genome-wide associations reveal human-mouse genetic convergence and modifiers of myogenesis, CPNE1 and STC2

Hernandez Cordero, A. I., Gonzales, N. M., Parker, C. C., Sokoloff, G., Vandenbergh, D. J., Cheng, R., Abney, M., Skol, A., Douglas, A., Palmer, A. A., Gregory, J. S. & Lionikas, A., 5 Dec 2019, In : American Journal of Human Genetics. 105, 6, p. 1222-1236 15 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity

Alhindi, Y., Vaanholt, L. M., Al-Tarrah, M., Gray, S. R., Speakman, J. R., Hambly, C., Alanazi, B. S., Gabriel, B. M., Lionikas, A. & Ratkevicius, A., 3 Mar 2019, In : Journal of Nutrition and Metabolism. 2019, 14 p., 8594825.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
7 Downloads (Pure)

Myostatin dysfunction does not protect from fasting-induced loss of muscle mass in mice

Fokin, A., Minderis, P., Venckunas, T., Lionikas, A., Kvedaras, M. & Ratkevicius, A., 1 Sep 2019, In : Journal of musculoskeletal & neuronal interactions. 19, 3, p. 342-353 12 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
2 Downloads (Pure)

Myostatin dysfunction is associated with lower physical activity and reduced improvements in glucose tolerance in response to caloric restriction in Berlin high mice

Kvedaras, M., Minderis, P., Krusnauskas, R., Lionikas, A. & Ratkevicius, A., Dec 2019, In : Experimental Gerontology. 128, 11 p., 110751.

Research output: Contribution to journalArticle

2018

Genome wide association analysis in a mouse advanced intercross line

Gonzales, N. M., Seo, J., Hernandez Cordero, A., St. Pierre, C., Gregory, J., Distler, M., Abney, M., Canzar, S., Lionikas, A. & Palmer, A., 4 Dec 2018, In : Nature Communications. 9, 5162.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)

Replication and discovery of musculoskeletal QTLs in LG/J and SM/J advanced intercross lines

Hernandez Cordero, A. I., Carbonetto, P., Verri, G. R., Gregory, J. S., Vandenbergh, D. J., Gyekis, J. P., Blizard, D. A. & Lionikas, A., Feb 2018, In : Physiological reports. 6, 4, 13561.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
9 Downloads (Pure)
2017

Fine mapping of genes determining extrafusal fiber properties in murine soleus muscle

Carroll, AM., Cheng, R., Collie-Duguid, ESR., Meharg, C., Scholz, ME., Fiering, S., Fields, JL., Palmer, AA. & Lionikas, A., 1 Mar 2017, In : Physiological Genomics. 49, 3, p. 141-150 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
6 Downloads (Pure)

Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10

Kvedaras, M., Minderis, P., Fokin, A., Ratkevicius, A., Venckunas, T. & Lionikas, A., 23 Jan 2017, In : Frontiers in Physiology. 8, 9.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
5 Downloads (Pure)

H55N polymorphism is associated with low citrate synthase activity which regulates lipid metabolism in mouse muscle cells

Gabriel, B. M., Al-Tarrah, M., Alhindi, Y. Z. Y., Kilikevicius, A., Venckunas, T., Gray, S. R., Lionikas, A. & Ratkevicius, A., 2 Nov 2017, In : PloS ONE. 12, 11, p. 1-20 20 p., e0185789.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
5 Downloads (Pure)
2016

Baseline Muscle Mass Is a Poor Predictor of Functional Overload-Induced Gain in the Mouse Model

Kilikevicius, A., Bunger, L. & Lionikas, A., 15 Nov 2016, In : Frontiers in Physiology. 534.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

Joyce, P. I., Fratta, P., Landman, A. S., Mcgoldrick, P., Wackerhage, H., Groves, M., Busam, B. S., Galino, J., Corrochano, S., Beskina, O. A., Esapa, C., Ryder, E., Carter, S., Stewart, M., Codner, G., Hilton, H., Teboul, L., Tucker, J., Lionikas, A., Estabel, J. & 9 others, Ramirez-Solis, R., White, J. K., Brandner, S., Plagnol, V., Bennet, D. L. H., Abramov, A. Y., Greensmith, L., Fisher, E. M. C. & Acevedo-Arozena, A., 15 Jan 2016, In : Human Molecular Genetics. 25, 2, p. 291-307 17 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
5 Downloads (Pure)

Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

Nicod, J., Davies, R. W., Cai, N., Hassett, C., Goodstadt, L., Cosgrove, C., Yee, B. K., Lionikaite, V., McIntyre, R. E., Remme, C. A., Lodder, E. M., Gregory, J. S., Hough, T., Joynson, R., Phelps, H., Nell, B., Rowe, C., Wood, J., Walling, A., Bopp, N. & 22 others, Bhomra, A., Hernandez-Pliego, P., Callebert, J., Aspden, R. M., Talbot, N. P., Robbins, P. A., Harrison, M., Fray, M., Launay, J-M., Pinto, Y. M., Blizard, D. A., Bezzina, C. R., Adams, D. J., Franken, P., Weaver, T., Wells, S., Brown, S. D. M., Potter, P. K., Klenerman, P., Lionikas, A., Mott, R. & Flint, J., 31 Aug 2016, In : Nature Genetics. 48, 8, p. 912-918 7 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
5 Downloads (Pure)

Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice

Parker, C. C., Gopalakrishnan, S., Carbonetto, P., Gonzales, N. M., Leung, E., Park, Y. J., Aryee, E., Davis, J., Blizard, D. A., Ackert-Bicknell, C. L., Lionikas, A., Pritchard, J. K. & Palmer, A. A., 31 Aug 2016, In : Nature Genetics. 48, 8, p. 919-926 8 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
6 Downloads (Pure)

Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice

Minderis, P., Kilikevicius, A., Baltusnikas, J., Alhindi, Y., Venckunas, T., Bunger, L., Lionikas, A. & Ratkevicius, A., Aug 2016, In : Scandinavian Journal of Medicine & Science in Sports. 26, 8, p. 894-901 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
6 Downloads (Pure)
2015
Open Access
File
2 Citations (Scopus)
4 Downloads (Pure)

Regenerated soleus muscle shows reduced creatine kinase efflux after contractile activity in vitro

Baltusnikas, J., Kilikevicius, A., Venckunas, T., Fokin, A., Lionikas, A. & Ratkevicius, A., Feb 2015, In : Applied Physiology Nutrition and Metabolism / Physiologie Appliquée, Nutrition et Métabolisme. 40, 2, p. 129-133 5 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)
2014

Discovery and refinement of muscle weight QTLs in B6 x D2 advanced intercross mice

Carbonetto, P., Cheng, R., Gyekis, J. P., Parker, C. C., Blizard, D. A., Palmer, A. A. & Lionikas, A., 15 Aug 2014, In : Physiological Genomics. 46, 16, p. 571-582 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis

Corrochano, S., Männikkö, R., Joyce, P. I., McGoldrick, P., Wettstein, J., Lassi, G., Raja Rayan, D. L., Blanco, G., Quinn, C., Liavas, A., Lionikas, A., Amior, N., Dick, J., Healy, E. G., Stewart, M., Carter, S., Hutchinson, M., Bentley, L., Fratta, P., Cortese, A. & 9 others, Cox, R., Brown, S. D. M., Tucci, V., Wackerhage, H., Amato, A. A., Greensmith, L., Koltzenburg, M., Hanna, M. G. & Acevedo-Arozena, A., Dec 2014, In : Brain. 137, 12, p. 3171-3185 15 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
5 Downloads (Pure)
2013

Analyses of muscle spindles in the soleus of six inbred mouse strains: Spind.les in soleus muscle

Lionikas, A., Smith, C. J., Smith, T. L., Bunger, L., Banks, R. W. & Bewick, G. S., Sep 2013, In : Journal of Anatomy. 223, 3, p. 289-296 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy

Judson, R. N., Gray, S. R., Walker, C., Carroll, A. M., Itzstein, C., Lionikas, A., Zammit, P. S., De Bari, C. & Wackerhage, H., 27 Mar 2013, In : PloS ONE. 8, 3, 12 p., e59622.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
5 Downloads (Pure)

Divergent physiological characteristics and responses to endurance training among inbred mouse strains

Kilikevicius, A., Venckunas, T., Zelniene, R., Carroll, A. M., Lionikaite, S., Ratkevicius, A. & Lionikas, A., Oct 2013, In : Scandinavian Journal of Medicine & Science in Sports. 23, 5, p. 657-668 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Genetic and genomic analyses of musculoskeletal differences between BEH and BEL strains

Lionikas, A., Kilikevicius, A., Bünger, L., Meharg, C., Carroll, A. M., Ratkevicius, A., Venckunas, T. & Blizard, D. A., 15 Oct 2013, In : Physiological Genomics. 45, 20, p. 940-947 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012

QTL analysis of type I and type IIA fibers in soleus muscle in a cross between LG/J and SM/J mouse strains

Carroll, A. M., Palmer, A. & Lionikas, A., Jan 2012, In : Frontiers in Genetics. 2, 9 p., 99.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
5 Downloads (Pure)

Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses

Lionikas, A., Meharg, C., Derry, J. M. J., Ratkevicius, A., Carroll, A. M., Vandenbergh, D. J. & Blizard, D. A., 5 Nov 2012, In : BMC Genomics. 13, 14 p., 592.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
5 Downloads (Pure)
2011

B6-MSM consomic mouse strains reveal multiple loci for genetic variation in sucrose octaacetate aversion

Ishii, A., Koide, T., Takahashi, A., Shiroishi, T., Hettinger, T., Frank, M., Savoy, L., Formaker, B., Yertutanol, S., Lionikas, A. & Blizard, D., Sep 2011, In : Behavior Genetics. 41, 5, p. 716-723 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2010

Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses

Lionikas, A., Cheng, R., Lim, J., Palmer, A. & Blizard, D., Sep 2010, In : Physiological Genomics. 42A, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Genomic analysis of variation in hindlimb musculature of mice from the C57BL/6J and DBA/2J lineage

Lionikas, A., Carlborg, Ö., Lu, L., Peirce, J. L., Williams, R. W., Yu, F., Vogler, G. P., McClearn, G. E. & Blizard, D. A., May 2010, In : Journal of Heredity. 101, 3, p. 360-367 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

H55N polymorphism as a likely cause of variation in citrate synthase activity of mouse skeletal muscle

Ratkevicius, A., Carroll, A. M., Kilikevicius, A., Venckunas, T., McDermott, K. T., Gray, S. R., Wackerhage, H. & Lionikas, A., 1 Oct 2010, In : Physiological Genomics. 42A, 2, p. 96-102 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2009

Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex differences and environmental influences

Blizard, D. A., Lionikas, A., Vandenbergh, D. J., Vasilopoulos, T., Gerhard, G. S., Griffith, J. W., Klein, L. C., Stout, J. T., Mack, H. A., Lakoski, J. M., Larsson, L., Spicer, J. M., Vogler, G. P. & McClearn, G. E., Feb 2009, In : Physiological Genomics. 36, 3, p. 158-166 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Bone, muscle, and physical activity: structural equation modeling of relationships and genetic influence with age

Lang, D. H., Conroy, D. E., Lionikas, A., Mack, H. A., Larsson, L., Vogler, G. P., Vandenbergh, D. J., Blizard, D. A., McClearn, G. E. & Sharkey, N. A., Sep 2009, In : Journal of Bone and Mineral Research. 24, 9, p. 1608-1617 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Genetic architecture for hole-board behaviors across substantial time intervals in young, middle-aged and old mice

Foreman, J. E., Lionikas, A., Lang, D. H., Gyekis, J. P., Krishnan, M., Sharkey, N. A., Gerhard, G. S., Grant, M. D., Vogler, G. P., Mack, H. A., Stout, J. T., Griffith, J. W., Lakoski, J. M., Hofer, S. M., McClearn, G. E., Vandenbergh, D. J. & Blizard, D. A., Oct 2009, In : Genes, Brain, and Behavior. 8, 7, p. 714-727 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains

Umemori, J., Nishi, A., Lionikas, A., Sakaguchi, T., Kuriki, S., Blizard, D. A. & Koide, T., 29 Jul 2009, In : BMC Genetics. 10, 11 p., 40.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
5 Downloads (Pure)
2008

Diverse effects of stanozolol in C57BL/6J and A/J mouse strains

Lionikas, A. & Blizard, D. A., Jun 2008, In : European Journal of Applied Physiology. 103, 3, p. 333-341 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Echocardiographic parameters in athletes of different sports

Venckunas, T., Lionikas, A., Marcinkeviciene, J. E., Raugaliene, R., Alekrinskis, A. & Stasiulis, A., Mar 2008, In : Journal of Sports Science and Medicine. 7, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Learning in the 2-bottle alcohol preference test

Blizard, D. A., Vandenbergh, D. J., Lionikas, A. & McClearn, G. E., Dec 2008, In : Alcoholism: Clinical and Experimental Research. 32, 12, p. 2041-2046 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2006

Anomaly of anatomical origin of soleus muscle

Lionikas, A., Glover, M. G., Yu, F., Larsson, L., Vogler, G. P., McClearn, G. E. & Blizard, D. A., 1 Mar 2006, In : Anatomical Science International. 81, 1, p. 47-49 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genetic determinants of weight of fast- and slow-twitch skeletal muscles in old mice

Lionikas, A., Blizard, D. A., Vandenbergh, D. J., Stout, J. T., Vogler, G. P., McClearn, G. E. & Larsson, L., 2006, In : Mammalian Genome. 17, 6, p. 615-628 14 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Human skeletal muscle myosin function at physiological and non-physiological temperatures

Lionikas, A., Li, M. & Larsson, L., 1 Feb 2006, In : Acta Physiologica. 186, 2, p. 151-158 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Muscle cell and motor protein function in patients with a IIa myosin missense mutation (Glu-706 to Lys)

Li, M., Lionikas, A., Yu, F., Tajsharghi, H., Oldfors, A. & Larsson, L., Nov 2006, In : Neuromuscular Disorders. 16, 11, p. 782-791 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

QTL influencing baseline hematocrit in the C57BL/6J and DBA/2J lineage: age-related effects

Johannes, F., Blizard, D. A., Lionikas, A., Lang, D. H., Vandenbergh, D. J., Stout, J. T., Strauss, J. A., McClearn, G. E. & Vogler, G. P., 2006, In : Mammalian Genome. 17, 6, p. 689-699 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2005

Adjusting data to body size: a comparison of methods as applied to quantitative trait loci analysis of musculoskeletal phenotypes

Lang, D. H., Sharkey, N. A., Lionikas, A., Mack, H. A., Larsson, L., Vogler, G. P., Vandenbergh, D. J., Blizard, D. A., Stout, J. T., Stitt, J. P. & McClearn, G. E., May 2005, In : Journal of Bone and Mineral Research. 20, 5, p. 748-757 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Genetic determinants of weight of fast- and slow-twitch skeletal muscle in 500-day-old mice of the C57BL/6J and DBA/2J lineage

Lionikas, A., Blizard, D. A., Gerhard, G. S., Vandenbergh, D. J., Stout, J. T., Vogler, G. P., McClearn, G. E. & Larsson, L., Apr 2005, In : Physiological Genomics. 21, 2, p. 184-192 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2003

Genetic architecture of fast- and slow-twitch skeletal muscle weight in 200-day-old mice of the C57BL/6J and DBA/2J lineage

Lionikas, A., Blizard, D. A., Vandenbergh, D. J., Glover, M. G., Stout, J. T., Vogler, G. P., McClearn, G. E. & Larsson, L., 2003, In : Physiological Genomics. 16, 1, p. 141-152 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2001

Effects of concentric and eccentric contractions on phosphorylation of MAPK(erk1/2) and MAPK(p38) in isolated rat skeletal muscle

Wretman, C., Lionikas, A., Widegren, U., Lännergren, J., Westerblad, H. & Henriksson, J., 15 Aug 2001, In : The Journal of Physiology. 535, Pt 1, p. 155-164 10 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)
2000

Differential activation of mitogen-activated protein kinase signalling pathways by isometric contractions in isolated slow- and fast-twitch rat skeletal muscle

Wretman, C., Widegren, U., Lionikas, A., Westerblad, H. & Henriksson, J., 1 Sep 2000, In : Acta Physiologica Scandinavica. 170, 1, p. 45-49 5 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Influence of exercise intensity on ERK/MAP kinase signalling in human skeletal muscle

Widegren, U., Wretman, C., Lionikas, A., Hedin, G. & Henriksson, J., 1 Dec 2000, In : Pflugers Archiv : European Journal of Physiology. 441, 2-3, p. 317-22 6 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)