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Research Output

2020

Inter-individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption: a Critical Review

Visser, E., Geleijnse, J. M. & de Roos, B., Apr 2020, In : Molecular Nutrition & Food Research. 64, 7, 22 p., e1900479.

Research output: Contribution to journalReview article

Open Access

Why interindividual variation in response to consumption of plant food bioactives matters for future personalised nutrition

Morand, C., De Roos, B., Garcia-Conesa, M. T., Gibney, E. R., Landberg, R., Manach, C., Milenkovic, D., Rodriguez-Mateos, A., Van de Wiele, T. & Tomas-Barberan, F., May 2020, In : Proceedings of the Nutrition Society. 79, 2, p. 225-235 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2019
Open Access
File
2 Downloads (Pure)

Future prospects for dissecting inter-individual variability in the absorption, distribution and elimination of plant bioactives of relevance for cardiometabolic endpoints

Landberg, R., Manach, C., Kerckhof, F-M., Minihane, A-M., Saleh, R. N. M., De Roos, B., Tomas-Barberan, F., Morand, C. & Van de Wiele, T., Nov 2019, In : European Journal of Nutrition. 58, Suppl 2, p. 21-36 16 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
5 Downloads (Pure)

Linking agroecosystems producing farmed seafood with food security and health status to better address the nutritional challenges in Bangladesh

de Roos, B., Roos, N., Mamun, A-A., Ahmed, T., Sneddon, A. A., Murray, F., Grieve, E. & Little, D. C., Nov 2019, In : Public Health Nutrition. 22, 16, p. 2941-2949 9 p.

Research output: Contribution to journalArticle

Open Access
File

Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats

Rodríguez-Gutiérrez, G., Rubio-Senent, F., Gómez-Carretero, A., Maya, I., Fernández-Bolaños, J., Duthie, G. G. & de Roos, B., Aug 2019, In : European Journal of Nutrition. 58, 5, p. 1847-1851 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Targeting the delivery of dietary plant bioactives to those who would benefit most: from science to practical applications

de Roos, B., Aura, A-M., Bronze, M., Cassidy, A., Garcia-Conesa, M. T. & Gibney, E. R., Nov 2019, In : European Journal of Nutrition. 58, Suppl 2, p. 65-73 9 p.

Research output: Contribution to journalReview article

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)
2018

Role of protein in healthy ageing

Donaldson, A. I. C., Johnstone, A. M., de Roos, B. & Myint, P. K., Oct 2018, In : European Journal of Integrative Medicine. 23, p. 32-36 5 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
4 Downloads (Pure)

SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice

Sergi, D., Campbell, F. M., Grant, C., Morris, A. C., Bachmair, E-M., Koch, C. E., McLean, F. H., Muller, A., Hoggard, N., de Roos, B., Porteiro, B., Boekschoten, M. V., McGillicuddy, F. C., Kahn, D., Nicol, P., Benzler, J., Mayer, C-D., Drew, J. E., Roche, H. M., Muller, M. & 4 others, Nogueiras, R., Diéguez, C., Tups, A. & Williams, L. M., 29 Nov 2018, In : Genes & Nutrition. 13, p. 1-14 14 p., 28.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
5 Downloads (Pure)
2017

Acute Consumption of Flavan-3-ol-Enriched Dark Chocolate Affects Human Endogenous Metabolism

Ostertag, L. M., Philo, M., Colquhoun, I. J., Tapp, H. S., Saha, S., Duthie, G. G., Kemsley, E. K., de Roos, B., Kroon, P. A. & Le Gall, G., 2017, In : Journal of Proteome Research. 16, 7, p. 2516-2526 11 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
9 Downloads (Pure)

Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy ageing and cardiometabolic risk reduction

Manach, C., Milenkovic, D., Van de Wiele, T., Rodriguez-Mateos, A., de Roos, B., Garcia-Conesa, M. T., Landberg, R., Gibney, E. R., Heinonen, M., Tomás-Barberán, F. & Morand, C., Jun 2017, In : Molecular Nutrition & Food Research. 61, 6, p. 1-16 16 p.

Research output: Contribution to journalArticle

Open Access
File
90 Citations (Scopus)
7 Downloads (Pure)

An extra virgin olive oil-rich diet intervention ameliorates the non-alcoholic steatohepatitis induced by a high-fat "Western type" diet in mice

Jurado-Ruiz, E., Varela, L. M., Luque, A., Berná, G., Cahuana, G., Martinez-Force, E., Gallego-Durán, R., Soria, B., de Roos, B., Gómez, M. R. & Martín, F., 1 Mar 2017, In : Molecular Nutrition & Food Research. 61, 3, p. 1-12 12 p., 1600549 .

Research output: Contribution to journalArticle

31 Citations (Scopus)

Availability and dose response of phytophenols from a wheat bran-rich cereal product in healthy human volunteers

Neacsu, M., McMonagle, J., Fletcher, R. J., Hulshof, T., Duncan, S. H., Scobbie, L., Duncan, G. J., Cantlay, L., Horgan, G., De Roos, B., Duthie, G. G. & Russell, W. R., 1 Mar 2017, In : Molecular Nutrition & Food Research. 61, 3, p. 1-15 15 p., 1600202.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
16 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
9 Downloads (Pure)

Personalised Interventions - A Precision Approach for the Next Generation of Dietary Intervention Studies

de Roos, B. & Brennan, L., 9 Aug 2017, In : Nutrients. 9, 8, p. 1-9 9 p., 847.

Research output: Contribution to journalReview article

Open Access
File
24 Citations (Scopus)
8 Downloads (Pure)
Open Access
File
22 Citations (Scopus)
7 Downloads (Pure)
Open Access
File
17 Citations (Scopus)
6 Downloads (Pure)
2016

Is life longer with a box of chocolates?

Donaldson, A. IC., de Roos, B., Johnstone, A. M. & Myint, P. K., Jul 2016, In : Heart. 102, 13, p. 990-991 2 p.

Research output: Contribution to journalEditorial

1 Downloads (Pure)
2015

Inhibitory and synergistic effects of natural olive phenols on human platelet aggregation and lipid peroxidation of microsomes from vitamin E-deficient rats

Rubio-Senent, F., de Roos, B., Duthie, G., Fernández-Bolaños, J. & Rodríguez-Gutiérrez, G., Dec 2015, In : European Journal of Nutrition. 54, 8, p. 1287-1295 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle

Arrabal, S., Lucena, M. A., Canduela, M. J., Ramos-Uriarte, A., Rivera, P., Serrano, A., Pavón, F. J., Decara, J., Vargas, A., Baixeras, E., Martín-Rufián, M., Márquez, J., Fernández-Llébrez, P., De Roos, B., Grandes, P., Rodríguez de Fonseca, F. & Suárez, J., 2015, In : PloS ONE. 10, 12, 23 p., e0145244.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
6 Downloads (Pure)
26 Citations (Scopus)
8 Citations (Scopus)
2014

Dietary manipulation of platelet function

Bachmair, E. M., Ostertag, L. M., Zhang, X. & De Roos, B., Nov 2014, In : Pharmacology & Therapeutics. 144, 2, p. 97-113 17 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes

Zhang, X., McGeoch, S. C., Megson, I. L., MacRury, S. M., Johnstone, A. M., Abraham, P., Pearson, D. W. M., De Roos, B., Holtrop, G., O'Kennedy, N. & Lobley, G. E., Jun 2014, In : Molecular Nutrition & Food Research. 58, 6, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
8 Downloads (Pure)

Platelet-derived microparticle count and surface molecule expression differ between subjects with and without type 2 diabetes, independently of obesity status

Zhang, X., McGeoch, S. C., Johnstone, A. M., Holtrop, G., Sneddon, A. A., Macrury, S. M., Megson, I. L., Pearson, D. W. M., Abraham, P., De Roos, B., Lobley, G. E. & O'Kennedy, N., May 2014, In : Journal of Thrombosis and Thrombolysis. 37, 4, p. 455-463 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism

Elliott, R. M., de Roos, B., Duthie, S. J., Bouwman, F. G., Rubio-Aliaga, I., Crosley, L. K., Mayer, C., Polley, A. C., Heim, C., Coort, S. L., Evelo, C. T., Mulholland, F., Daniel, H., Mariman, E. C. & Johnson, I. T., Nov 2014, In : Genes & Nutrition. 9, 6, p. 1-11 11 p., 432.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2013

Bound phytophenols from ready-to-eat cereals: comparison with other plant-based foods

Neacsu, M., McMonagle, J., Fletcher, R. J., Scobbie, L., Duncan, G. J., Cantlay, L., de Roos, B., Duthie, G. G. & Russell, W. R., Dec 2013, In : Food Chemistry. 141, 3, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Flavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way: A randomized-controlled human intervention trial

Ostertag, L. M., Kroon, P. A., Wood, S., Horgan, G., Cienfuegos-Jovellanos, E., Saha, S., Duthie, G. G. & De Roos, B., Feb 2013, In : Molecular Nutrition & Food Research. 57, 2, p. 191-202 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Mechanisms of Fish Oil-Modulated Inflammation and Health

de Roos, B., 2013, Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases. Watson, R. R. & Preedy, V. R. (eds.). Elsevier Inc, p. 545-553 9 p. 42

Research output: Chapter in Book/Report/Conference proceedingChapter

Personalised nutrition: ready for practice?

De Roos, B., Feb 2013, In : Proceedings of the Nutrition Society. 72, 1, p. 48-52 5 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2012

A diet rich in unsaturated fatty acids prevents progression toward heart failure in a rabbit model of pressure and volume overload

Den Ruijter, H. M., Verkerk, A. O., Schumacher, C. A., Houten, S. M., Belterman, C. N. W., Baartscheer, A., Brouwer, I. A., van Bilsen, M., de Roos, B. & Coronel, R., 2012, In : Circulation. Heart Failure. 5, 3, p. 376-384 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A key role for dietary bioactives in the prevention of atherosclerosis

de Roos, B., Jul 2012, In : Molecular Nutrition & Food Research. 56, 7, p. 1001-1002 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats: a proteomics and network analysis approach

Rodríguez-Gutiérrez, G., Duthie, G. G., Wood, S., Morrice, P., Nicol, F., Reid, M., Cantlay, L. L., Kelder, T., Horgan, G., Fernández-Bolaños Guzmán, J. & De Roos, B., Jul 2012, In : Molecular Nutrition & Food Research. 56, 7, p. 1131-1147 17 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Effect of supplementation with an 80:20 cis9, trans11 conjugated linoleic acid blend on the human platelet proteome

Bachmair, E-M., Bots, M. L., Mennen, L. I., Kelder, T., Evelo, C. T., Horgan, G. W., Ford, I. & de Roos, B., Jul 2012, In : Molecular Nutrition & Food Research. 56, 7, p. 1148-1159 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
34 Citations (Scopus)

Inter-organ proteomic analysis reveals insights into the molecular mechanisms underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in ob/ob mice

Rungapamestry, V., McMonagle, J., Reynolds, C., Rucklidge, G., Reid, M., Duncan, G., Ross, K., Horgan, G., Toomey, S., Moloney, A. P., de Roos, B. & Roche, H. M., Feb 2012, In : Proteomics. 12, 3, p. 461-476 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Potential benefits of ready meal reformulation for the elderly

Duthie, G. G. & De Roos, B., 2012, Aberdeen: Rowett Institute of Nutrition and Health. 4 p. (Rowett Food Reports; no. 4)

Research output: Book/ReportCommissioned Report

Open Access

Proteomic approaches to predict bioavailability of fatty acids and their influence on cancer and chronic disease prevention

de Roos, B. & Romagnolo, D. F., 1 Jul 2012, In : The Journal of Nutrition. 142, 7, p. 1370S-1376S 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2011

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

Bouwman, F. G., De Roos, B., Rubio-Aliaga, I., Crosley, L. K., Duthie, S. J., Mayer, C., Horgan, G., Polley, A. C., Heim, C., Coort, S. LM., Evelo, C. T., Mulholland, F., Johnson, I. T., Elliott, R. M., Daniel, H. & Mariman, E. CM., 25 Mar 2011, In : BMC Medical Genomics. 4, 12 p., 24.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
6 Downloads (Pure)

A high intake of industrial or ruminant trans fatty acids does not affect the plasma proteome in healthy men

de Roos, B., Wanders, A. J., Wood, S., Horgan, G., Rucklige, G., Reid, M., Siebelink, E. & Brouwer, I. A., Oct 2011, In : Proteomics. 11, 19, p. 3928-3934 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Alterations in hepatic one-carbon metabolism and related pathways following a high fat dietary intervention

Rubio-Aliaga, I., De Roos, B., Sailer, M., McLoughlin, G., van Boekschoten, M., van Erk, M., Bachmair, E. M., van Schothorst, E., Keijer, J., Coort, S., Evelo, C., Gibney, M., Daniel, H., Muller, M., Kleemann, R. & Brennan, L., Apr 2011, In : Physiological Genomics. 43, 8, p. 408-416 9 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Anti-platelet effects of olive oil extract: in vitro functional and proteomic studies

de Roos, B., Zhang, X., Rodriguez Gutierrez, G., Wood, S., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Cantlay, L. L., Duthie, G. G. & O'Kennedy, N., Oct 2011, In : European Journal of Nutrition. 50, 7, p. 553-562 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Determination of 3,4-dihydroxyphenylglycol, hydroxytyrosol and tyrosol purified from olive oil by-products with HPLC in animal plasma and tissues

Rodriguez-Gutierrez, G., Wood, S., Fernandez-Bolanos Guzman, J., Duthie, G. G. & de Roos, B., 15 Jun 2011, In : Food Chemistry. 126, 4, p. 1948-1952 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

In vitro anti-platelet effects of simple plant-derived phenolic compounds are only found at high, non-physiological concentrations

Ostertag, L. M., O'Kennedy, N., Horgan, G., Kroon, P. A., Duthie, G. G. & de Roos, B., Nov 2011, In : Molecular Nutrition & Food Research. 55, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Metabolomics of prolonged fasting in humans reveals new catabolic markers

Rubio-Aliaga, I., de Roos, B., Duthie, S. J., Crosley, L. K., Mayer, C., Horgan, G., Colquhoun, I. J., Le Gall, G., Huber, F., Kremer, W., Rychlik, M., Wopereis, S., van Ommen, B., Schmidt, G., Heim, C., Bouwman, F. G., Mariman, E. C., Mulholland, F., Johnson, I. T., Polley, A. C. & 2 others, Elliott, R. M. & Daniel, H., Sep 2011, In : Metabolomics. 7, 3, p. 375-387 13 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2010

Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation

Duthie, S. J., Horgan, G., De Roos, B., Rucklidge, G., Reid, M., Duncan, G., Pirie, L., Basten, G. P. & Powers, H. J., 5 Apr 2010, In : Journal of Proteome Research. 9, 4, p. 1941-1950 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Dietary supplementation with cis-9, trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adults

Sluijs, I., Plantinga, Y., De Roos, B., Mennen, L. I. & Bots, M. L., Jan 2010, In : The American Journal of Clinical Nutrition. 91, 1, p. 175-183 9 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Impact of dietary polyphenols on human platelet function: a critical review of controlled dietary intervention studies

Ostertag, L. M., O'Kennedy, N., Kroon, P. A., Duthie, G. G. & De Roos, B., Jan 2010, In : Molecular Nutrition & Food Research. 54, 1, p. 60-81 22 p.

Research output: Contribution to journalLiterature review

88 Citations (Scopus)