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Research Output

  • 737 Citations
  • 27 Article
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2019

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Muller, B. & Connolly, B., Aug 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
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7 Downloads (Pure)
2017

An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly

Philippe, L., Pandarakalam, G. C., Fasimoye, R., Harrison, N., Connolly, B., Pettitt, J. & Muller, B., 21 Aug 2017, In : Nucleic Acids Research. 45, 14, p. 8474-8483 10 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
6 Downloads (Pure)
2014

Operons Are a Conserved Feature of Nematode Genomes

Pettitt, J., Philippe, L., Sarkar, D., Johnston, C., Gothe, H., Massie, D., Connolly, B. & Muller, B., Aug 2014, In : Genetics. 197, 4, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2010

SL2-like spliced leader RNAs in the basal nematode Prionchulus punctatus: new insight into the evolution of nematode SL2 RNAs

Harrison, N., Kalbfleisch, A., Connolly, B., Pettitt, J. & Muller, B., Aug 2010, In : RNA . 16, 8, p. 1500-1507 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The evolution of spliced leader trans-splicing in nematodes

Pettitt, J., Harrison, N., Stansfield, I., Connolly, B. & Müller, B., Aug 2010, In : Biochemical Society Transactions. 38, 4, p. 1125-1130 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2009

Cloning and analysis of a Trichinella pseudospiralis muscle larva secreted serine protease gene

Cwiklinski, K., Meskill, D., Robinson, M. W., Pozio, E., Appleton, J. A. & Connolly, B., 23 Feb 2009, In : Veterinary Parasitology. 159, 3-4, p. 268-271 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Micro-environmental conditions modulate protein secretion and infectivity of the Trichinella spiralis L1 larva

Bolas-Fernandez, F., Dea-Ayuela, M. A., Connolly, B. & Robinson, M. W., 23 Feb 2009, In : Veterinary Parasitology. 159, 3-4, p. 236-239 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2008
20 Citations (Scopus)
2007

Comparative analysis of the excretory-secretory proteome of the muscle larva of Trichinella pseudospiralis and Trichinella spiralis

Robinson, M. W., Greig, R., Beattie, K. A., Lamont, D. J. & Connolly, B., Feb 2007, In : International Journal for Parasitology. 37, 2, p. 139-148 10 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis

Robinson, M. W., Massie, D. H. & Connolly, B., Jan 2007, In : Molecular and Biochemical Parasitology. 151, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2005

Profiling excretory/secretory proteins of Trichinella spiralis muscle larvae by two-dimensional gel electrophoresis and mass spectrometry

Robinson, M. W., Gare, D. C. & Connolly, B., Sep 2005, In : Veterinary Parasitology. 132, 1-2, p. 37-41 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Proteomic analysis of the excretory-secretory proteins of the Trichinella spiralis L1 larva, a nematode parasite of skeletal muscle

Robinson, M. W. & Connolly, B., Nov 2005, In : Proteomics. 5, 17, p. 4525-4532 7 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
2004

Developmental regulation and secretion of nematode-specific cysteine-glycine domain proteins in Trichinella spiralis

Gare, D. C., Boyd, J. & Connolly, B., Apr 2004, In : Molecular and Biochemical Parasitology. 134, 2, p. 257-266 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2001

Secretion of the novel Trichinella protein TSJ5 by T. spiralis and T. pseudospiralis muscle larvae

Kuratli, S., Hemphill, A., Lindh, J., Smith, D. F. & Connolly, B., 1 Jul 2001, In : Molecular and Biochemical Parasitology. 115, 2, p. 199-208 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1999

Trichinella spp.

Kuratli, S., Lindh, J. G., Gottstein, B., Smith, D. F. & Connolly, B., 1 Nov 1999, In : Experimental Parasitology. 93, 3, p. 153-159 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
1998

Identification of a developmentally regulated Trichinella spiralis protein that inhibits MyoD-specific protein

Lindh, J. G., Connolly, B., McGhie, D. L. & Smith, D. F., 1 Apr 1998, In : Molecular and Biochemical Parasitology. 92, 1, p. 163-175 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The major 36 kDa Neospora caninum tachyzoite surface protein is closely related to the major Toxoplasma gondii surface antigen

Sonda, S., Fuchs, N., Connolly, B., Fernandez, P., Gottstein, B. & Hemphill, A., 30 Nov 1998, In : Molecular and Biochemical Parasitology. 97, 1-2, p. 97-108 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
1997

Characterization of a cDNA-clone encoding Nc-p43, a major Neospora caninum tachyzoite surface protein

Hemphill, A., Felleisen, R., Connolly, B., Gottstein, B., Hentrich, B. & Müller, N., 1 Dec 1997, In : Parasitology. 115 ( Pt 6), p. 581-90 10 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Epidemiological investigation of trichinellosis in Switzerland

Gottstein, B., Pozio, E., Connolly, B., Gamble, H. R., Eckert, J. & Jakob, H. P., 1 Oct 1997, In : Veterinary Parasitology. 72, 2, p. 201-207 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
1996

Molecular cloning of a myoD-like gene from the parasitic nematode, Trichinella spiralis

Connolly, B., Trenholme, K. & Smith, D. F., 30 Oct 1996, In : Molecular and Biochemical Parasitology. 81, 2, p. 137-149 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1995

Trichinella spiralis

Connolly, B., Ingram, L. J. & Smith, D. F., 1 May 1995, In : Experimental Parasitology. 80, 3, p. 488-498 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
1992

Biological roles of the Escherichia coli RuvA, RuvB and RuvC proteins revealed

West, S. C. & Connolly, B., 1 Oct 1992, In : Molecular Microbiology. 6, 19, p. 2755-2759 5 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
1991

Resolution of Holliday junctions in vitro requires the Escherichia coli ruvC gene product

Connolly, B., Parsons, C. A., Benson, F. E., Dunderdale, H. J., Sharples, G. J., Lloyd, R. G. & West, S. C., 15 Jul 1991, In : PNAS. 88, 14, p. 6063-6067 5 p.

Research output: Contribution to journalArticle

140 Citations (Scopus)
1990

Genetic recombination in Escherichia coli: Holliday junctions made by RecA protein are resolved by fractionated cell-free extracts

Connolly, B. & West, S. C., 1 Nov 1990, In : PNAS. 87, 21, p. 8476-8480 5 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
1988

Physical monitoring of mating type switching in Saccharomyces cerevisiae

Connolly, B., White, C. I. & Haber, J. E., 1 Jun 1988, In : Molecular and Cellular Biology. 8, 6, p. 2342-2349 8 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Physical monitoring of meiotic and mitotic recombination in yeast

Haber, J. E., Borts, R. H., Connolly, B., Lichten, M., Rudin, N. & White, C. I., 1 Jan 1988, In : Progress in Nucleic Acid Research and Molecular Biology. 35, p. 209-259 51 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
1983

Mating factor dependence of G1 cell cycle mutants of Saccharomyces cerevisiae

Connolly, B., Bugeja, V. C., Piggott, J. R. & Carter, B. L. A., 1983, In : Current Genetics. 7, 4, p. 309-312 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)