• 1640 Citations
19992020

Research output per year

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Fingerprint Dive into the research topics where Charles Harrington is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Research Output

Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Cranston, A. L., Wysocka, A., Steczkowska, M., Zadrozny, M., Palasz, E., Harrington, C. R., Theuring, F., Wischik, C., Riedel, G. & Niewiadomska, G., 3 Feb 2020, (Accepted/In press) In : Brain Communications.

Research output: Contribution to journalArticle

Concentration-dependent activity of hydromethylthionine on clinical decline and brain atrophy in a randomized controlled trial in behavioural variant frontotemporal dementia (bvFTD)

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 4 Mar 2020, (Accepted/In press) In : Journal of Alzheimer's Disease.

Research output: Contribution to journalArticle

  • Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

    Schelter, B. O., Shiells, H. C., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Riedel, G., Gauthier, S., Jia, J., Bentham, P., Kook, K., Storey, J. M. D., Harrington, C. R. & Wischik, C. M., 26 Nov 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 931-946 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)
    1 Downloads (Pure)

    Increased Cholinergic Response in α-Synuclein Transgenic Mice (h-α-synL62)

    König, M., Berlin, B., Schwab, K., Frahm, S., Theuring, F., Wischik, C. M., Harrington, C. R., Riedel, G. & Klein, J., 2019, In : ACS Chemical Neuroscience. 10, 4, p. 1915-1922 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • Mechanisms of anticholinesterase interference with tau aggregation inhibitor activity in a tau-transgenic mouse model

    Riedel, G., Klein, J., Niewiadomska, G., Kondak, C., Schwab, K., Lauer, D., Magbagbeolu, M., Steczkowska, M., Zadrozny, M., Wydrych, M., Cranston, A., Melis, V., Coelho Dos Santos, R., Theuring, F., Harrington, C. & Wischik, C., 30 Jan 2019, (Accepted/In press) In : Current Alzheimer Research.

    Research output: Contribution to journalArticle

  • Impacts

    Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease

    Claude Wischik (Participant), Charles Harrington (Participant), John Storey (Participant), Janet Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven Kemp (Participant), James Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant), C Marshall (Participant)

    Impact: Quality of life Impacts, Economic Impacts