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Fingerprint Dive into the research topics where Charles Harrington is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Tauopathies Medicine & Life Sciences
tau Proteins Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Pathology Medicine & Life Sciences
Synucleins Medicine & Life Sciences
Methylene Blue Medicine & Life Sciences
Agglomeration Chemical Compounds

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Research Output 1999 2019

Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

Schelter, B. O., Shiells, H. C., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Riedel, G., Gauthier, S., Jia, J., Bentham, P., Kook, K., Storey, J. M. D., Harrington, C. R. & Wischik, C. M., 26 Nov 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 931-946 16 p.

Research output: Contribution to journalArticle

Open Access
File
Atrophy
Alzheimer Disease
Brain
Therapeutics
Pharmaceutical Preparations

Increased Cholinergic Response in α-Synuclein Transgenic Mice (h-α-synL62)

König, M., Berlin, B., Schwab, K., Frahm, S., Theuring, F., Wischik, C. M., Harrington, C. R., Riedel, G. & Klein, J., 2019, In : ACS Chemical Neuroscience. 10, 4, p. 1915-1922 8 p.

Research output: Contribution to journalArticle

Open Access
File
Synucleins
Cholinergic Agents
Transgenic Mice
Acetylcholine
Choline O-Acetyltransferase

Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study

Flores-Rodríguez, P., Harrington, C. R., Wischik, C. M., Ibarra-Bracamontes, V., Zarco, N., Navarrete, A., Martínez-Maldonado, A., Guadarrama-Ortíz, P., Villanueva-Fierro, I., Ontiveros-Torres, M. A., Perry, G., Alonso, A. D., Florán-Garduño, B., Segovia, J. & Luna-Muñoz, J., 17 Sep 2019, In : Journal of Alzheimer's Disease. 71, 2, p. 631-645 15 p.

Research output: Contribution to journalArticle

Open Access
File
tau Proteins
Neuroblastoma
Cell Cycle
Cell Division
Alzheimer Disease
7 Citations (Scopus)
19 Downloads (Pure)

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

Frahm, S., Melis, V., Horsley, D., Rickard, J. E., Riedel, G., Fadda, P., Scherma, M., Harrington, C. R., Wischik, C. M., Theuring, F. & Schwab, K., 26 Feb 2018, In : Behavioural Brain Research. 339, p. 153-168 16 p.

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Transgenic Mice
Parkinson Disease
Lewy Body Disease
Amphetamine
3 Citations (Scopus)
11 Downloads (Pure)
Open Access
File
Synucleins
Transgenic Mice
Proteins
Parkinson Disease
Endopeptidase K

Impacts

Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease

Claude Wischik (Participant), Charles Harrington (Participant), John Storey (Participant), Janet Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven Kemp (Participant), James Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant), C Marshall (Participant)

Impact: Quality of life Impacts, Economic Impacts