David Malcolm St Clair


    • AB25 2ZD

    • 28830 Citations
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    Research Output 1999 2019

    17 Citations (Scopus)
    4 Downloads (Pure)

    A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing

    Hu, X., Zhang, B., Liu, W., Paciga, S., He, W., Lanz, T. A., Kleiman, R., Dougherty, B., Hall, S. K., Mcintosh, A. M., Lawrie, S. M., Power, A., John, S. L., Blackwood, D., St Clair, D. & Brandon, N. J., 1 Jan 2014, In : Molecular Psychiatry. 19, 8, p. 857-858 2 p.

    Research output: Contribution to journalLetter

    Open Access
    6 Citations (Scopus)

    Multiplex amplicon quantification screening the ABCA13 gene for copy number variation in schizophrenia and bipolar disorder

    Pickard, B. S., Van Den Bossche, M. J. A., Malloy, M. P., Johnstone, M., Lenaerts, A. S., Nordin, A., Goossens, D., St Clair, D., Muir, W. J., Nilsson, L. G., Sabbe, B., Adolfsson, R., Blackwood, D. H. R. & Del-Favero, J., Oct 2012, In : Psychiatric Genetics. 22, 5, p. 269-270 2 p.

    Research output: Contribution to journalLetter

    2606 Citations (Scopus)

    Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    St Clair, D. M., Purcell, M., Wray, N. R., Stone, J., Visscher, P. M., O'Donovan, M. C., Sullivan, P. F., Sklar, P. & The International Schizophrenia Consortium (ISC), 6 Aug 2009, In : Nature. 460, 7256, p. 748-752 5 p.

    Research output: Contribution to journalLetter

    Bipolar Disorder
    Genome-Wide Association Study
    1169 Citations (Scopus)

    Common variants conferring risk of schizophrenia

    Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietiläinen, O. P. H., Mors, O., Mortensen, P. B., Sigurdsson, E., Gustafsson, O., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T., Suvisaari, J., Lonnqvist, J., Paunio, T., Børglum, A. D. & 31 others, Hartmann, A., Fink-Jensen, A., Nordentoft, M., Hougaard, D., Norgaard-Pedersen, B., Böttcher, Y., Olesen, J., Breuer, R., Möller, H-J., Giegling, I., Rasmussen, H. B., Timm, S., Mattheisen, M., Bitter, I., Réthelyi, J. M., Magnusdottir, B. B., Sigmundsson, T., Olason, P., Masson, G., Gulcher, J. R., Haraldsson, M., Fossdal, R., Thorgeirsson, T. E., Thorsteinsdottir, U., Ruggeri, M., Tosato, S., Franke, B., Strengman, E., Walker, N., St Clair, D. & Genetic Risk and Outcome in Psychosis (GROUP), 6 Aug 2009, In : Nature. 460, 7256, p. 744-747 4 p.

    Research output: Contribution to journalLetter

    Genome-Wide Association Study
    Major Histocompatibility Complex
    1128 Citations (Scopus)

    Rare chromosomal deletions and duplications increase risk of schizophrenia

    Stone, J. L., O'Donovan, M. C., Gurling, H., Kirov, G. K., Blackwood, D. H. R., Corvin, A., Craddock, N. J., Gill, M., Hultman, C. M., Lichtenstein, P., McQuillin, A., Pato, C. N., Ruderfer, D. M., Owen, M. J., St Clair, D., Sullivan, P. F., Sklar, P., Purcell, S. M., Scolnick, E. M., Holmans, P. A. & 31 others, Georgieva, L., Nikolov, I., Norton, N., Williams, H., Williams, N. M., Toncheva, D., Milanova, V., Thelander, E. F., Morris, D. W., O'Dushlaine, C. T., Kenny, E., Waddington, J. L., Choudhury, K., Datta, S., Pimm, J., Thirumalai, S., Puri, V., Krasucki, R., Lawrence, J., Quested, D., Bass, N., Curtis, D., Crombie, C., Fraser, G., Kwan, S. L., Muir, W. J., McGhee, K. A., Pickard, B., Malloy, P., Maclean, A. W. & The International Schizophrenia Consortium (ISC), 11 Sep 2008, In : Nature. 455, 7210, p. 237-241 5 p.

    Research output: Contribution to journalLetter

    17 Citations (Scopus)

    Bipolar 1 disorder is not associated with the RGS4, PRODH, COMT and GRK3 genes

    Prata, D. P., Breen, G., Munro, J., Sinclair, M., Osborne, S., Li, T., Kerwin, R., St. Clair, D. & Collier, D. A., Dec 2006, In : Psychiatric Genetics. 16, 6, p. 229-230 2 p.

    Research output: Contribution to journalLetter

    33 Citations (Scopus)

    Candidate gene association studies of the alpha4 (CHRNA4) and beta2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease

    Cook, L. J., Horrobin, L. W., Taylor, A. E., Brayne, C., Evans, J. G., Xuereb, J., Cairns, N. J., Pritchard, A., Lemmon, H. A., Mann, D., St Clair, D. M., Turic, D., Hollingworth, P., Moore, P. J., Jehu, L., Archer, N., Walter, S., Foy, C., Edmondson, A. & Powell, J., 2004, In : Neuroscience Letters. 358, p. 142-146 4 p.

    Research output: Contribution to journalLetter

    32 Citations (Scopus)

    A family-based association study of T1945C polymorphism in the proline dehydrogenase gene and schizophrenia in the Chinese population

    Fan, J. B., Ma, J., Zhang, C. S., Tang, J. X., Gu, N. F., Feng, G. Y., St Clair, D. M. & He, L., 2003, In : Neuroscience Letters. 338(3), p. 252-254 2 p.

    Research output: Contribution to journalLetter

    6 Citations (Scopus)

    Apolipoprotein-491 promoter polymorphism is an independent risk factor for Alzheimer's disease

    Yang, J. D., Feng, G. Y., Zhang, J., Cheung, J., St Clair, D. M., He, L. & Ichimura, K., 2003, In : Neuroscience Letters. p. 215-216 1 p.

    Research output: Contribution to journalLetter

    14 Citations (Scopus)

    Apolipoprotein E ε4 allele is a risk factor for late-onset Alzheimer's disease and vascular dementia in Han Chinese

    Zhang, J. G., Yang, J. G., Lin, Z. X., He, L., Feng, G. Y., Ma, X. Y., Wang, C. F., Lu, P. F., Song, S. B., Dong, X. Z., St Clair, D. & Breen, G., Apr 2001, In : International Journal of Geriatric Psychiatry. 16, 4, p. 438-439 2 p.

    Research output: Contribution to journalLetter

    7 Citations (Scopus)

    Screening British CADASIL families for mutations in the NOTCH3 gene

    De Lange, R. P. J., Bolt, J., Reid, E., Da Silva, R., Shaw, D. J. & St Clair, D. M., 18 May 2000, In : Journal of Medical Genetics. 37, 3, p. 224-225 2 p.

    Research output: Contribution to journalLetter

    Open Access