• 34232 Citations
19972020

Research output per year

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Research Output

102T/C polymorphism of serotonin receptor type 2A gene is not associated with schizophrenia in either Chinese or British populations

He, L., Li, T., Melville, C., Liu, S., Feng, G. Y., Gu, N. F., Fox, H., Shaw, D., Breen, G., Liu, X. H., Sham, P., Brown, J., Collier, D. & St Clair, D., 1999, In : American Journal of Medical Genetics. 88, p. 95-98 4 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

-141 C Del/Ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population

Breen, G., Brown, J., Maude, S., Fox, H., Collier, D., Li, T., Arranz, M., Shaw, D. & St Clair, D., 1999, In : American Journal of Medical Genetics. 88, p. 407-410 4 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

ABCA1 gene polymoprhism and lipid profile in a Scottish population

Pasdar, A., Cumming, A. M., St Clair, D. M. & MacLeod, M. J., 2005.

Research output: Contribution to conferenceAbstract

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

The International Schizophrenia Consortium (ISC), 1 Feb 2012, In : Journal of Medical Genetics. 49, 2, p. 96-103 8 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

A case control and family based association study of the neuregulin1 gene and schizophrenia

Zhao, X., Shi, Y., Tang, J., Tang, R., Yu, L., Gu, N., Feng, G., Zhu, S., Liu, H., Xing, Y., Zhao, S., Sang, H., Guan, Y., St Clair, D. & He, L., 2004, In : Journal of Medical Genetics. 41, p. 31-34 4 p.

Research output: Contribution to journalArticle

A case control and family based association study of the neuregulin 1 gene and schizophrenia

Zhao, X., Shi, Y., Tang, J., Tang, R., Yu, L., Gu, N., Feng, G., Zhu, S. M., Liu, H., Xing, Y., Xhao, S., Sang, H., Guan, Y., St Clair, D. M. & He, L., 2004, In : Journal of Medical Genetics. 41, p. 31-34 3 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Accuracy and sensitivity of DNA pooling with microsatellite repeats using capillary electrophoresis

Breen, G., Sham, P., Li, T., Shaw, D., Collier, D. A. & St Clair, D., 1999, In : Molecular and Cellular Probes. 13, p. 359-365 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

Raychaudhuri, S., Korn, J. M., McCarroll, S. A., The International Schizophrenia Consortium (ISC), Altshuler, D., Sklar, P., Purcell, S., Daly, M. J. & St Clair, D. M., 9 Sep 2010, In : PLoS Genetics. 6, 9, 12 p., e1001097.

Research output: Contribution to journalArticle

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101 Citations (Scopus)
4 Downloads (Pure)

A classification model of schizophrenia using a multivariate eye movement phenotype

Benson, P. J., Beedie, S. A., Giegling, I., Rujescu, D. & St Clair, D. M., 2010, In : European Psychiatry. 25, S1, p. 611 1 p., P01-398.

Research output: Contribution to journalAbstract

A comprehensive family-based replication study of schizophrenia genes

Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, Rujescu, D., St Clair, D., Werge, T., Hultman, C. M., Delisi, L. E., Sullivan, P. & Van Den Oord, E. J., 1 Jun 2013, In : JAMA Psychiatry. 70, 6, p. 573-581 9 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression

Knight, H. M., Pickard, B. S., Maclean, A., Malloy, M. P., Soares, D. C., McRae, A. F., Condie, A., White, A., Hawkins, W., McGhee, K., van Beck, M., MacIntyre, D. J., Starr, J. M., Deary, I. J., Visscher, P. M., Porteous, D. J., Cannon, R. E., St Clair, D., Muir, W. J. & Blackwood, D. H. R., 11 Dec 2009, In : American Journal of Human Genetics. 85, 6, p. 833-46 14 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

ADAMTSL3 as a candidate gene for schizophrenia: Gene sequencing and ultra-high density association analysis by imputation

Dow, D. J., Huxley-Jones, J., Hall, J. M., Francks, C., Maycox, P. R., Kew, J. N. C., Gloger, I. S., Mehta, N. A. L., Kelly, F. M., Muglia, P., Breen, G., Jugurnauth, S., Pederoso, I., St.Clair, D., Rujescu, D. & Barnes, M. R., 1 Apr 2011, In : Schizophrenia Research. 127, 1-3, p. 28-34 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A family-based and case-control association study of the NOTCH4 gene and schizophrenia

Fan, J. B., Tang, J. X., Gu, N. F., Feng, G. Y., Zou, F. G., Xing, Y. L., Shi, J. G., Zhao, S. M., Zhu, S. M., Ji, L. P., Sun, W. W., Zheng, Y. L., Liu, W. Q., Breen, G., St. Clair, D. & He, L., 3 Jan 2002, In : Molecular Psychiatry. 7, p. 100-103 4 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

A family-based association study of T1945C polymorphism in the proline dehydrogenase gene and schizophrenia in the Chinese population

Fan, J. B., Ma, J., Zhang, C. S., Tang, J. X., Gu, N. F., Feng, G. Y., St Clair, D. M. & He, L., 2003, In : Neuroscience Letters. 338(3), p. 252-254 2 p.

Research output: Contribution to journalLetter

32 Citations (Scopus)

A genome-wide investigation of SNPs and CNVs in schizophrenia

Need, A. C., Ge, D., Weale, M. E., Maia, J., Feng, S., Heinzen, E. L., Shianna, K. V., Yoon, W., Kasperaviciute, D., Gennarelli, M., Strittmatter, W. J., Bonvicini, C., Rossi, G., Jayathilake, K., Cola, P. A., McEvoy, J. P., Keefe, R. S. E., Fisher, E. M. C., St Jean, P. L., Giegling, I. & 13 others, Hartmann, A. M., Möller, H-J., Ruppert, A., Fraser, G., Crombie, C., Middleton, L. T., St Clair, D., Roses, A. D., Muglia, P., Francks, C., Rujescu, D., Meltzer, H. Y. & Goldstein, D. B., 6 Feb 2009, In : PLoS Genetics. 5, 2, 19 p., e1000373.

Research output: Contribution to journalArticle

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351 Citations (Scopus)
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A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

GROUP Investigators, 1 Apr 2010, In : Human Molecular Genetics. 19, 7, p. 1379-1386 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

A long-range restriction map across 3 Mb of the chromosome 11 breakpoint region of a translocation linked to schizophrenia: Localization of the breakpoint and the search for neighbouring genes

Millar, J. K., Brown, J., Maule, J. C., Shibasaki, Y., Christie, S., Lawson, D., Anderson, S., Wilson-Annan, J. C., Devon, R. S., St Clair, D. M., Blackwood, D. H. R., Muir, W. J. & Porteous, D. J., 2 Nov 1998, In : Psychiatric Genetics. 8, 3, p. 175-181 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

An association study between the transthyretin (TTR) gene and mental retardation

Li, J., Gao, J. J., Zhang, F. C., Xing, Q. H., Dang, F. L., Gao, X. C., Duan, S. W., Zheng, Z. J., Qian, X. Q., Qin, W., Li, X. W., Han, Y. F., Li, J., Feng, G. Y., St Clair, D. M. & He, L., 2006, In : European Archives of Psychiatry and Clinical Neuroscience. 256, 4, p. 230-235 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis

Prata, D. P., Breen, G., Osborne, S., Munro, J., St. Clair, D. & Collier, D., Jun 2009, In : Psychiatric Genetics. 19, 3, p. 113-116 4 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

An inherited duplication at the gene p21 protein-activated Kinase 7 (PAK7) is a risk factor for psychosis

Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L. P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B., Kelleher, E., Fahey, C., Molinos, I., Bellini, S., Pirinen, M., Strange, A., Freeman, C., Thiselton, D. L., Elves, R. L., Regan, R. & 39 others, Ennis, S., Dinan, T. G., McDonald, C., Murphy, K. C., O'Callaghan, E., Waddington, J. L., Walsh, D., O'Donovan, M., Grozeva, D., Craddock, N., Stone, J., Scolnick, E., Purcell, S., Sklar, P., Coe, B., Eichler, E. E., Ophoff, R., Buizer, J., Szatkiewicz, J., Hultman, C., Sullivan, P., Gurling, H., Mcquillin, A., St Clair, D., Rees, E., Kirov, G., Walters, J., Blackwood, D., Johnstone, M., Donohoe, G., The International Schizophrenia Consortium (ISC), SGENE+ Consortium, O'Neill, F. A., The Wellcome Trust Case Control Consortium 2 (WTCCC2), Kendler, K. S., Gill, M., Riley, B. P., Spencer, C. C. A. & Corvin, A., 15 Jun 2014, In : Human Molecular Genetics. 23, 12, p. 3316-3326 11 p.

Research output: Contribution to journalArticle

Open Access
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21 Citations (Scopus)
7 Downloads (Pure)

An integrated genetic-epigenetic analysis of schizophrenia: Evidence for co-localization of genetic associations and differential DNA methylation

Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, A. R., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., Kaprio, J., Toulopoulou, T., Pol, H. E. H., Bohlken, M. M., Kahn, R. S., Nenadic, I., Hultman, C. M., Murray, R. M., Collier, D. A., Bass, N. & 4 others, Gurling, H., McQuillin, A., Schalkwyk, L. & Mill, J., 30 Aug 2016, In : Genome Biology. 17, 176.

Research output: Contribution to journalArticle

Open Access
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110 Citations (Scopus)
7 Downloads (Pure)

Apolipoprotein-491 promoter polymorphism is an independent risk factor for Alzheimer's disease

Yang, J. D., Feng, G. Y., Zhang, J., Cheung, J., St Clair, D. M., He, L. & Ichimura, K., 2003, In : Neuroscience Letters. p. 215-216 1 p.

Research output: Contribution to journalLetter

7 Citations (Scopus)

Apolipoprotein E-491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population

Yang, J. D., Feng, G. Y., Zhang, J., Cheung, J., St Clair, D. & He, L., 2003, In : Neuroscience Letters. 350, p. 25-28 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
35 Citations (Scopus)

Apolipoprotein E e4 allele is a risk factor for late-onset Alzheimer's disease and vascular dementia in Han Chinese

Zhang, J. G., Yang, J. D., Feng, G. Y., Ma, X. Y., Wang, C. F., Lu, P. F., Song, S. B., Dong, X. Z., Lin, Z. X., Breen, G. D., St Clair, D. M. & He, L., 2001, In : International Journal of Geriatric Psychiatry. 4, p. 217-219 2 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Apolipoprotein E is a genetic risk factor for fetal iodine deficiency disorder in China

Wang, H. Y., Zhang, F. C., Gao, J. J., Fan, J. B., Liu, P., Zheng, Z. J., Xi, H., Sun, Y., Gao, X. C., Huang, T. Z., Ke, Z. J., Guo, G. R., Feng, G. Y., Breen, G., St Clair, D. & He, L., 2000, In : Molecular Psychiatry. 5, p. 363-368 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Apolipoprotein E ε4 allele is a risk factor for late-onset Alzheimer's disease and vascular dementia in Han Chinese

Zhang, J. G., Yang, J. G., Lin, Z. X., He, L., Feng, G. Y., Ma, X. Y., Wang, C. F., Lu, P. F., Song, S. B., Dong, X. Z., St Clair, D. & Breen, G., Apr 2001, In : International Journal of Geriatric Psychiatry. 16, 4, p. 438-439 2 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

Are interleukin-1 gene polymorphisms risk factors or disese modifiers in Alzheimer's disease?

Green, E. K., Harris, J. M., Lemmon, H. A., Lambert, J. C., Chartier-Harlin, M. C., St Clair, D. M., Mann, A., Iwatsubo, T. & Lendon, C., 2002, In : Neurology. 58, p. 1566-1568 2 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Are the estrogen receptors involved in Alzheimer's disease?

Lambert, J. C., Harris, J. M., Lemmon, H. A., Cummings, A., Coates, J., Mann, D. & St Clair, D. M., 29 Jun 2001, In : Neuroscience Letters. 306, 3, p. 193-197 4 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Association analysis of the glycogen synthase kinase-3 beta gene in bipolar disorder

Nishiguchi, N., Breen, G., Russ, C., St Clair, D. & Collier, D., 2006, In : Neuroscience Letters. 394, p. 243-245 3 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Association analysis of the RGS4 gene in Han Chinese and Scottish populations with schizophrenia

Zhang, F., St Clair, D., Liu, X., Sun, X., Sham, P. C., Crombie, C., Ma, X., Wang, Q., Meng, H., Deng, W., Yates, P., Hu, X., Walker, N., Murray, R. M., Collier, D. A. & Li, T., 2005, In : Genes, Brain, and Behavior. 4, p. 444-448 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Association between Alzheimer's disease and the NOS3 gene

Dahiyat, M., Cumming, A., Harrington, C., Wischik, C., Xuereb, J., Corrigan, F., Breen, G., Shaw, D. & St Clair, D., 1999, In : Annals of Neurology. 46, p. 664-667 4 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Association between angiotensin-converting enzyme gene and late onset Alzheimer's disease in Han Chinese

Yang, J. D., Feng, G. Y., Zhang, J., Lin, Z. X., Shen, T., Breen, G., St Clair, D. & He, L., 2000, In : Neuroscience Letters. 295, p. 41-44 4 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population

Helgadottir, A., Gretasdottir, S., St Clair, D. M., Maolescu, A., Cheung, J. K. S., Thorleifsson, G., Pasdar, A., Grant, S. F., Whalley, L. J., Hakonarson, H., Thorsteinsdottir, U., Kong, A., Gulcher, J. R., Stefansson, K. & MacLeod, M. J., Mar 2005, In : American Journal of Human Genetics. 76, 3, p. 505-509 4 p.

Research output: Contribution to journalArticle

220 Citations (Scopus)

Association of APOE gene with schizophrenia in Chinese: a possible risk facator in times of malnutrition

Liu, W. Q., Breen, G., Zhang, J. G., Li, S., Gu, N. F., Feng, G. Y., Bai, S. C., Shen, T., Yu, A., Xue, H., St Clair, D. & He, L., 1 Aug 2003, In : Schizophrenia Research. 62, 3, p. 225-230 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Association of DAO and G72(DAOA)/G30 genes with bipolar affective disorder

Prata, D., Breen, G. D., Osborne, S., Munro, J., St Clair, D. M. & Collier, D., 5 Sep 2008, In : American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 147B, 6, p. 914-917 4 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Association of Neuregulin 1 with schizophrenia confirmed in a Scottish population

Stefansson, H., Sarginson, J., Kong, A., Yates, P., Steinthorsdottir, V., Gudfinnsson, E., Gunnarsdottir, S., Walker, N., Peturrsson, H., Crombie, C. M., Ingason, A., Gulcher, J. R., Stefansson, J. R. & St Clair, D. M., Jan 2003, In : American Journal of Human Genetics. 72, 1, p. 83-87 4 p.

Research output: Contribution to journalArticle

471 Citations (Scopus)

Association of the dysbindin gene with bipolar affective disorder

Breen, G., Prata, D., Osborne, S., Munro, J., Sinclair, M., Li, T., Staddon, S., Dempster, D., Sainz, R., Arroyo, B., Kerwin, R. W., St. Clair, D. & Collier, D., Sep 2006, In : American Journal of Psychiatry. 163, 9, p. 1636-1638 3 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease

Pritchard, A., Harris, J., Pritchard, C. W., St Clair, D., Lemmon, H., Lambert, J. C., Chartier-Harlin, M. C., Hayes, A., Thaker, U., Iwatsubo, T., Mann, D. M. A. & Lendon, C., 2005, In : Neuroscience Letters. 382, p. 221-226 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Association study of a (TG)n dinucleotide repeat at chromosome 15q13.3 and schizophrenia in the Chinese population

Ma, J., Fan, J-B., Bian, L., Zhang, C-S., Li, X-W., Gu, N-F., Feng, G-Y., St Clair, D. M. & He, L., 30 May 2008, In : Psychiatry Research. 159, 1-2, p. 245-249 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Association study of CHRFAM7A copy number and 2bp deletion polymorphisms with schizophrenia and bipolar affective disorder

Flomen, R. H., Collier, D. A., Osborne, S., Munro, J., Breen, G., St Clair, D. M. & Makoff, A. J., 2006, In : American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 141B, 6, p. 571-575 5 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia

Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E. & 12 others, St Clair, D., Tosato, S., Werge, T., Stefansson, K., González, J. C., Valero, J., Gutiérrez-Zotes, A., Labad, A., Martorell, L., Vilella, E., Carracedo, Á. & Costas, J., 15 Jan 2012, In : Biological Psychiatry. 71, 2, p. 169-177 9 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Association study of the CACN1A4 (SCA6) triplet repeat and schizophrenia

Breen, G., Fox, H., Glen, I., Collier, D., Shaw, D. & St Clair, D., 1999, In : Psychiatric Genetics. 9, p. 111-113 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing

Hu, X., Zhang, B., Liu, W., Paciga, S., He, W., Lanz, T. A., Kleiman, R., Dougherty, B., Hall, S. K., Mcintosh, A. M., Lawrie, S. M., Power, A., John, S. L., Blackwood, D., St Clair, D. & Brandon, N. J., 1 Jan 2014, In : Molecular Psychiatry. 19, 8, p. 857-858 2 p.

Research output: Contribution to journalLetter

Open Access
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17 Citations (Scopus)
6 Downloads (Pure)

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

Datta, S. R., McQuillin, A., Rizig, M., Blaveri, E., Thirumalai, S., Kalsi, G., Lawrence, J., Bass, N. J., Puri, V., Choudhury, K., Pimm, J., Crombie, C., Fraser, G., Walker, N., Curtis, D., Zvelebil, M., Pereira, A., Kandaswamy, R., St Clair, D. & Gurling, H. M. D., 1 Jun 2010, In : Molecular Psychiatry. 15, 6, p. 615-628 14 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia

Hansen, T., Ingason, A., Djurovic, S., Melle, I., Fenger, M., Gustafsson, O., Jakobsen, K. D., Rasmussen, H. B., Tosato, S., Rietschel, M., Frank, J., Owen, M., Bonetto, C., Suvisaari, J., Thygesen, J. H., Pétursson, H., Lönnqvist, J., Sigurdsson, E., Giegling, I., Craddock, N. & 12 others, O'Donovan, M. C., Ruggeri, M., Cichon, S., Ophoff, R. A., Pietiläinen, O., Peltonen, L., Nöthen, M. M., Rujescu, D., St Clair, D., Collier, D. A., Andreassen, O. A. & Werge, T., 1 Jul 2011, In : Biological Psychiatry. 70, 1, p. 59-63 5 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Balanced translocation linked to psychiatric disorder, glutamate, and cortical structure/function

Thomson, P. A., Duff, B., Blackwood, D. H. R., Romaniuk, L., Watson, A., Whalley, H. C., Li, X., Dauvermann, M. R., Moorhead, T. W. J., Bois, C., Ryan, N. M., Redpath, H., Hall, L., Morris, S. W., Van Beek, E. J. R., Roberts, N., Porteous, D. J., St Clair, D., Whitcher, B., Dunlop, J. & 5 others, Brandon, N. J., Hughes, Z. A., Hall, J., McIntosh, A. & Lawrie, S. M., 10 Aug 2016, In : npj Schizophrenia. 2, 9 p., 16024.

Research output: Contribution to journalArticle

Open Access
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24 Citations (Scopus)
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BDNF gene is a risk factor for schizophrenia in a Scottish population

Neves-Pereira, M. D. L., Cheung, J. K. S., Pasdar, A., Zhang, F., Breen, G. D., Yates, P., Crombie, C. M., Walker, N. & St Clair, D. M., Jan 2005, In : Molecular Psychiatry. 10, p. 208-212 4 p.

Research output: Contribution to journalArticle

227 Citations (Scopus)

Bipolar 1 disorder is not associated with the RGS4, PRODH, COMT and GRK3 genes

Prata, D. P., Breen, G., Munro, J., Sinclair, M., Osborne, S., Li, T., Kerwin, R., St. Clair, D. & Collier, D. A., Dec 2006, In : Psychiatric Genetics. 16, 6, p. 229-230 2 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)