• 34608 Citations
19972020

Research output per year

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Research Output

2011

Genome-wide association study identifies five new schizophrenia loci

Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N., Malhotra, A. K. & 31 others, Purcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Børglum, A. D., Brown, M. A., Bruggeman, R., Buccola, N. G. & Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Oct 2011, In : Nature Genetics. 43, 10, p. 969-976 8 p.

Research output: Contribution to journalArticle

1295 Citations (Scopus)

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

Fraser, G., Genetic Risk and Outcome in Psychosis (GROUP) & The International Schizophrenia Consortium (ISC), 1 Nov 2011, In : Molecular Psychiatry. 16, 11, p. 1117-1129 13 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

Reilly, M. P., Li, M., He, J., Ferguson, J. F., Stylianou, I. M., Mehta, N. N., Burnett, M. S., Devaney, J. M., Knouff, C. W., Thompson, J. R., Horne, B. D., Stewart, A. F. R., Assimes, T. L., Wild, P. S., Allayee, H., Nitschke, P. L., Patel, R. S., Martinelli, N., Girelli, D., Quyyumi, A. A. & 14 others, Anderson, J. L., Erdmann, J., Hall, A. S., Schunkert, H., Quertermous, T., Blankenberg, S., Hazen, S. L., Roberts, R., Kathiresan, S., Samani, N. J., Epstein, S. E., Rader, D. J., Myocardial Infarction Genetics Consortium & St Clair, D., 29 Jan 2011, In : The Lancet. 377, 9763, p. 383-392 10 p.

Research output: Contribution to journalArticle

349 Citations (Scopus)

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., Guan, W., Mattingsdal, M., McQuillin, A., Kwan, P., Wienker, T. F., Daly, M., Dudbridge, F., Holmans, P. A. & 31 others, Lin, D., Burmeister, M., Greenwood, T. A., Hamshere, M. L., Muglia, P., Smith, E. N., Zandi, P. P., Nievergelt, C. M., McKinney, R., Shilling, P. D., Schork, N. J., Bloss, C. S., Foroud, T., Koller, D. L., Gershon, E. S., Liu, C., Badner, J. A., Scheftner, W. A., Lawson, W. B., Nwulia, E. A., Hipolito, M., Coryell, W., Rice, J., Byerley, W., McMahon, F. J., Schulze, T. G., Berrettini, W., Li, J., Breen, G., St Clair, D. & Psychiatric GWAS Consortium Bipolar Disorder Working Group, Oct 2011, In : Nature Genetics. 43, 10, p. 977-983 7 p.

Research output: Contribution to journalArticle

895 Citations (Scopus)

Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility

The International Schizophrenia Consortium (ISC), 2011, In : Molecular Psychiatry. 16, 3, p. 286-292 7 p.

Research output: Contribution to journalArticle

160 Citations (Scopus)

Polygenic dissection of the bipolar phenotype

Hamshere, M. L., O'Donovan, M. C., Jones, I. R., Jones, L., Kirov, G., Green, E. K., Moskvina, V., Grozeva, D., Bass, N., McQuillin, A., Gurling, H., St Clair, D., Young, A. H., Ferrier, I. N., Farmer, A., McGuffin, P., Sklar, P., Purcell, S., Holmans, P. A., Owen, M. J. & 1 others, Craddock, N., 1 Apr 2011, In : British Journal of Psychiatry. 198, 4, p. 284-288 5 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Prevention and schizophrenia: the role of dietary factors

McGrath, J., Brown, A. & St Clair, D., Mar 2011, In : Schizophrenia Bulletin. 37, 2, p. 272-283 12 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

Chen, J., Lee, G., Fanous, A. H., Zhao, Z., Jia, P., O'Neill, A., Walsh, D., Kendler, K. S., Chen, X., The International Schizophrenia Consortium (ISC) & St Clair, D., Sep 2011, In : Schizophrenia Research. 131, 1-3, p. 43-51 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2010

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function

Raychaudhuri, S., Korn, J. M., McCarroll, S. A., The International Schizophrenia Consortium (ISC), Altshuler, D., Sklar, P., Purcell, S., Daly, M. J. & St Clair, D. M., 9 Sep 2010, In : PLoS Genetics. 6, 9, 12 p., e1001097.

Research output: Contribution to journalArticle

Open Access
File
101 Citations (Scopus)
4 Downloads (Pure)

A classification model of schizophrenia using a multivariate eye movement phenotype

Benson, P. J., Beedie, S. A., Giegling, I., Rujescu, D. & St Clair, D. M., 2010, In : European Psychiatry. 25, S1, p. 611 1 p., P01-398.

Research output: Contribution to journalAbstract

A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

GROUP Investigators, 1 Apr 2010, In : Human Molecular Genetics. 19, 7, p. 1379-1386 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

Datta, S. R., McQuillin, A., Rizig, M., Blaveri, E., Thirumalai, S., Kalsi, G., Lawrence, J., Bass, N. J., Puri, V., Choudhury, K., Pimm, J., Crombie, C., Fraser, G., Walker, N., Curtis, D., Zvelebil, M., Pereira, A., Kandaswamy, R., St Clair, D. & Gurling, H. M. D., 1 Jun 2010, In : Molecular Psychiatry. 15, 6, p. 615-628 14 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

Thorleifsson, G., Walters, G. B., Hewitt, A. W., Masson, G., Helgason, A., Dewan, A., Sigurdsson, A., Jonasdottir, A., Gudjonsson, S. A., Magnusson, K. P., Stefansson, H., Lam, D. S. C., Tam, P. O. S., Gudmundsdottir, G. J., Southgate, L., Burdon, K. P., Gottfredsdottir, M. S., Aldred, M. A., Mitchell, P., St Clair, D. & 27 others, Collier, D. A., Tang, N., Sveinsson, O., MacGregor, S., Martin, N. G., Cree, A. J., Gibson, J., MacLeod, A., Jacob, A., Ennis, S., Young, T. L., Chan, J. C. N., Karwatowski, W. S. S., Hammond, C. J., Thordarson, K., Zhang, M., Wadelius, C., Lotery, A. J., Trembath, R. C., Pang, C. P., Hoh, J., Craig, J. E., Kong, A., MacKey, D. A., Jonasson, F., Thorsteinsdottir, U. & Stefansson, K., 12 Oct 2010, In : Nature Genetics. 42, 10, p. 906-909 4 p.

Research output: Contribution to journalArticle

268 Citations (Scopus)

Erratum to: evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging

Nicodemus, K. K., Callicott, J. H., Higier, R. G., Luna, A., Nixon, C., Lipska, B. K., Vakkalanka, R., Giegling, I., Rujescu, D., St Clair, D. M., Muglia, P., Shugart, Y. Y. & Weinberger, D. R., 1 Apr 2010, In : Human Genetics. 127, 4, p. 453-454 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging

Nicodemus, K. K., Callicott, J. H., Higier, R. G., Luna, A., Nixon, D. C., Lipska, B. K., Vakkalanka, R., Giegling, I., Rujescu, D., St Clair, D., Muglia, P., Shugart, Y. Y. & Weinberger, D. R., Apr 2010, In : Human Genetics. 127, 4, p. 441-452 12 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Frontal brain function and visual exploration of natural scenes in schizophrenia

Beedie, S. A., St Clair, D. M. & Rujescu, D., 2010, In : European Psychiatry. 25, S1, p. 1104 1 p., P03-124.

Research output: Contribution to journalAbstract

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Craddock, N., Hurles, M. E., Cardin, N., Pearson, R. D., Plagnol, V., Robson, S., Vukcevic, D., Barnes, C., Conrad, D. F., Giannoulatou, E., Holmes, C., Marchini, J. L., Stirrups, K., Tobin, M. D., Wain, L. V., Yau, C., Aerts, J., Ahmad, T., Andrews, T. D., Arbury, H. & 31 others, Attwood, A., Auton, A., Ball, S. G., Balmforth, A. J., Barrett, J. C., Barroso, I., Barton, A., Bennett, A. J., Bhaskar, S., Blaszczyk, K., Bowes, J., Brand, O. J., Braund, P. S., Bredin, F., Breen, G. D., Brown, M. J., Bruce, I. N., Bull, J., Burren, O. S., Burton, J., Byrnes, J., Caesar, S., Clee, C. M., Coffey, A. J., Connell, J. M. C., Cooper, J. D., Hocking, L., Reid, D. M., St Clair, D. M., Webster, J. & Wellcome Trust Case Control Consortium, 1 Apr 2010, In : Nature. 464, 7289, p. 713-720 8 p.

Research output: Contribution to journalArticle

584 Citations (Scopus)

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Liu, J. Z., Tozzi, F., Waterworth, D. M., Pillai, S. G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C. W., Yuan, X., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Barroso, I., Khaw, K-T., Grundy, S., Barter, P., Mahley, R. & 31 others, Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Farmer, A., McGuffin, P., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H-E., Rawal, R., Dahmen, N., Lamina, C., Polasek, O., Zgaga, L., Huffman, J., Campbell, S. E., Kooner, J., Chambers, J. C., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., St Clair, D. M. & Wellcome Trust Case Control Consortium, May 2010, In : Nature Genetics. 42, 5, p. 436-440 5 p.

Research output: Contribution to journalArticle

452 Citations (Scopus)

Multivariate eye movement psychophysiology accurately differentiates schizophrenia cases from unaffected controls

Benson, P. J., Beedie, S. A., Geigling, I., Rujescu, D. & St. Clair, D., Apr 2010, In : Schizophrenia Research. 117, 2-3, p. 248-249 2 p.

Research output: Contribution to journalArticle

Penetrance for copy number variants associated with schizophrenia

Vassos, E., Collier, D. A., Holden, S., Patch, C., Rujescu, D., St Clair, D. M. & Lewis, C. M., 1 Sep 2010, In : Human Molecular Genetics. 19, 17, p. 3477-3481 5 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

Perseverative eye movements in obsessive-compulsive disorder and schizophrenia

Shephard, E., Beedie, S. A., Kuriakose, J., Benson, P. J. & St Clair, D. M., Sep 2010, In : Perception. 39, ECVP Abstract Supplement, p. 37 1 p.

Research output: Contribution to journalAbstract

Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia

Xu, M., Xing, Q., Li, S., Zheng, Y., Wu, S., Gao, R., Yu, L., Guo, T., Yang, Y., Liu, J., Zhang, A., Zhao, X., He, G., Zhou, J., Wang, L., Xuan, J., Du, J., Li, X., Feng, G., Lin, Z. & 4 others, Xu, Y., St Clair, D. M., Lin, Z. & He, L., 16 Aug 2010, In : Progress in Neuro -Psychopharmacology & Biological Psychiatry. 34, 6, p. 1026-1032 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Grozeva, D., Kirov, G., Ivanov, D., Jones, I. R., Jones, L., Green, E. K., St Clair, D. M., Young, A. H., Ferrier, N., Farmer, A. E., McGuffin, P., Holmans, P. A., Owen, M. J., O'Donovan, M. C., Craddock, N. & Wellcome Trust Case Control Consortium, Apr 2010, In : Archives of General Psychiatry. 67, 4, p. 318-327 10 p.

Research output: Contribution to journalArticle

140 Citations (Scopus)

Scanpaths as a generalised deficit in schizophrenia

Beedie, S. A., Shephard, E., Giegling, I., Rujescu, D., St Clair, D. M. & Benson, P. J., Sep 2010, In : Perception. 39, ECVP Abstract Supplement, p. 34 1 p.

Research output: Contribution to journalAbstract

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotypeGABAA receptors in bipolar disorder

Craddock, N., Jones, L., Jones, I. R., Kirov, G., Green, E. K., Grozeva, D., Moskvina, V., Nikolov, I., Hamshere, M. L., Vukcevic, D., Caesar, S., Gordon-Smith, K., Fraser, C., Russell, E., Norton, N., Breen, G. D., St Clair, D. M., Collier, D. A., Young, A. H., Ferrier, I. N. & 6 others, Farmer, A., McGuffin, P., Holmans, P. A., Donnelly, P., Owen, M. J. & O'Donovan, M. C., Feb 2010, In : Molecular Psychiatry. 15, 2, p. 146-153 8 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)
26 Citations (Scopus)

Variation at the GABAA receptor gene, rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder

Green, E. K., Grozeva, D., Moskvina, V., Hamshere, M. L., Jones, I. R., Jones, L., Forty, L., Caesar, S., Gordon-Smith, K., Fraser, C., Russell, E., St Clair, D., Young, A. H., Ferrier, N., Farmer, A., McGuffin, P., Holmans, P. A., Owen, M. J., O'Donovan, M. C. & Craddock, N., 1 Oct 2010, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 153, 7, p. 1347-1349 3 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2009

A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression

Knight, H. M., Pickard, B. S., Maclean, A., Malloy, M. P., Soares, D. C., McRae, A. F., Condie, A., White, A., Hawkins, W., McGhee, K., van Beck, M., MacIntyre, D. J., Starr, J. M., Deary, I. J., Visscher, P. M., Porteous, D. J., Cannon, R. E., St Clair, D., Muir, W. J. & Blackwood, D. H. R., 11 Dec 2009, In : American Journal of Human Genetics. 85, 6, p. 833-46 14 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

A genome-wide investigation of SNPs and CNVs in schizophrenia

Need, A. C., Ge, D., Weale, M. E., Maia, J., Feng, S., Heinzen, E. L., Shianna, K. V., Yoon, W., Kasperaviciute, D., Gennarelli, M., Strittmatter, W. J., Bonvicini, C., Rossi, G., Jayathilake, K., Cola, P. A., McEvoy, J. P., Keefe, R. S. E., Fisher, E. M. C., St Jean, P. L., Giegling, I. & 13 others, Hartmann, A. M., Möller, H-J., Ruppert, A., Fraser, G., Crombie, C., Middleton, L. T., St Clair, D., Roses, A. D., Muglia, P., Francks, C., Rujescu, D., Meltzer, H. Y. & Goldstein, D. B., 6 Feb 2009, In : PLoS Genetics. 5, 2, 19 p., e1000373.

Research output: Contribution to journalArticle

Open Access
File
352 Citations (Scopus)
4 Downloads (Pure)

An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis

Prata, D. P., Breen, G., Osborne, S., Munro, J., St. Clair, D. & Collier, D., Jun 2009, In : Psychiatric Genetics. 19, 3, p. 113-116 4 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

St Clair, D. M., Purcell, M., Wray, N. R., Stone, J., Visscher, P. M., O'Donovan, M. C., Sullivan, P. F., Sklar, P. & The International Schizophrenia Consortium (ISC), 6 Aug 2009, In : Nature. 460, 7256, p. 748-752 5 p.

Research output: Contribution to journalLetter

2882 Citations (Scopus)

Common variants conferring risk of schizophrenia

Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietiläinen, O. P. H., Mors, O., Mortensen, P. B., Sigurdsson, E., Gustafsson, O., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T., Suvisaari, J., Lonnqvist, J., Paunio, T., Børglum, A. D. & 31 others, Hartmann, A., Fink-Jensen, A., Nordentoft, M., Hougaard, D., Norgaard-Pedersen, B., Böttcher, Y., Olesen, J., Breuer, R., Möller, H-J., Giegling, I., Rasmussen, H. B., Timm, S., Mattheisen, M., Bitter, I., Réthelyi, J. M., Magnusdottir, B. B., Sigmundsson, T., Olason, P., Masson, G., Gulcher, J. R., Haraldsson, M., Fossdal, R., Thorgeirsson, T. E., Thorsteinsdottir, U., Ruggeri, M., Tosato, S., Franke, B., Strengman, E., Walker, N., St Clair, D. & Genetic Risk and Outcome in Psychosis (GROUP), 6 Aug 2009, In : Nature. 460, 7256, p. 744-747 4 p.

Research output: Contribution to journalLetter

1219 Citations (Scopus)

Copy number variation and schizophrenia

St Clair, D., Jan 2009, In : Schizophrenia Bulletin. 35, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Deregulation of EIF4E: a novel mechanism for autism

Neves-Pereira, M., Muller, B., Massie, D., Williams, J. H. G., O'Brien, P. C. M., Hughes, A., Shen, S-B., St Clair, D. & Miedzybrodzka, Z., Nov 2009, In : Journal of Medical Genetics. 46, 11, p. 759-765 7 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Disruption of the neurexin 1 gene is associated with schizophrenia

Rujescu, D., Ingason, A., Cichon, S., Pietiläinen, O. P. H., Barnes, M. R., Toulopoulou, T., Picchioni, M., Vassos, E., Ettinger, U., Bramon, E., Murray, R., Ruggeri, M., Tosato, S., Bonetto, C., Steinberg, S., Sigurdsson, E., Sigmundsson, T., Petursson, H., Gylfason, A., Olason, P. I. & 31 others, Hardarsson, G., Jonsdottir, G. A., Gustafsson, O., Fossdal, R., Giegling, I., Möller, H-J., Hartmann, A. M., Hoffmann, P., Crombie, C., Fraser, G., Walker, N., Lonnqvist, J., Suvisaari, J., Tuulio-Henriksson, A., Djurovic, S., Melle, I., Andreassen, O. A., Hansen, T., Werge, T., Kiemeney, L. A., Franke, B., Veltman, J., Buizer-Voskamp, J. E., Sabatti, C., Ophoff, R. A., Rietschel, M., Nöthen, M. M., Stefansson, K., Peltonen, L., St Clair, D. & GROUP Investigators, 2009, In : Human Molecular Genetics. 18, 5, p. 988-996 9 p.

Research output: Contribution to journalArticle

350 Citations (Scopus)

Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept

Hamshere, M. L., Green, E. K., Jones, I. R., Jones, L., Moskvina, V., Kirov, G., Grozeva, D., Nikolov, I., Vukcevic, D., Caesar, S., Gordon-Smith, K., Fraser, C., Russell, E., Breen, G., St Clair, D., Collier, D. A., Young, A. H., Ferrier, I. N., Farmer, A., McGuffin, P. & 4 others, Holmans, P. A., Owen, M. J., O'Donovan, M. C. & Craddock, N., 1 Jul 2009, In : British Journal of Psychiatry. 195, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Identifying relationships among genomic disease regions: Predicting genes at pathogenic SNP associations and rare deletions

The International Schizophrenia Consortium (ISC), 26 Jun 2009, In : PLoS Genetics. 5, 6, e1000534.

Research output: Contribution to journalArticle

Open Access
326 Citations (Scopus)

Prenatal malnutrition and adult schizophrenia: Further evidence from the 1959-1961 Chinese famine

Xu, M-Q., Sun, W-S., Liu, B-X., Feng, G-Y., Yu, L., Yang, L., He, G., Sham, P., Susser, E., St Clair, D. & He, L., May 2009, In : Schizophrenia Bulletin. 35, 3, p. 568-576 9 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

The impact of divergence time on the nature of population structure: an example from Iceland

Price, A. L., Helgason, A., Palsson, S., Stefansson, H., St Clair, D., Andreassen, O. A., Reich, D., Kong, A. & Stefansson, K., 5 Jun 2009, In : PLoS Genetics. 5, 6, 10 p., e1000505.

Research output: Contribution to journalArticle

Open Access
File
71 Citations (Scopus)
4 Downloads (Pure)

Treatment and Diagnosis of Behavioural Disorders

Miedzybrodzka, Z. H., St Clair, D. M., Muller, B. M., Neves-Pereira, M. D. L. & Massie, D., 2009, IPC No. C12Q 1/68 (2006.01), Patent No. WO/2009/144480

Research output: Patent

2008

Association of DAO and G72(DAOA)/G30 genes with bipolar affective disorder

Prata, D., Breen, G. D., Osborne, S., Munro, J., St Clair, D. M. & Collier, D., 5 Sep 2008, In : American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 147B, 6, p. 914-917 4 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Association study of a (TG)n dinucleotide repeat at chromosome 15q13.3 and schizophrenia in the Chinese population

Ma, J., Fan, J-B., Bian, L., Zhang, C-S., Li, X-W., Gu, N-F., Feng, G-Y., St Clair, D. M. & He, L., 30 May 2008, In : Psychiatry Research. 159, 1-2, p. 245-249 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Rare chromosomal deletions and duplications increase risk of schizophrenia

Stone, J. L., O'Donovan, M. C., Gurling, H., Kirov, G. K., Blackwood, D. H. R., Corvin, A., Craddock, N. J., Gill, M., Hultman, C. M., Lichtenstein, P., McQuillin, A., Pato, C. N., Ruderfer, D. M., Owen, M. J., St Clair, D., Sullivan, P. F., Sklar, P., Purcell, S. M., Scolnick, E. M., Holmans, P. A. & 31 others, Georgieva, L., Nikolov, I., Norton, N., Williams, H., Williams, N. M., Toncheva, D., Milanova, V., Thelander, E. F., Morris, D. W., O'Dushlaine, C. T., Kenny, E., Waddington, J. L., Choudhury, K., Datta, S., Pimm, J., Thirumalai, S., Puri, V., Krasucki, R., Lawrence, J., Quested, D., Bass, N., Curtis, D., Crombie, C., Fraser, G., Kwan, S. L., Muir, W. J., McGhee, K. A., Pickard, B., Malloy, P., Maclean, A. W. & The International Schizophrenia Consortium (ISC), 11 Sep 2008, In : Nature. 455, 7210, p. 237-241 5 p.

Research output: Contribution to journalLetter

1157 Citations (Scopus)

Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1

Shen, S., Lang, B., Nakamoto, C., Zhang, F., Pu, J., Kuan, S-L., Chatzi, C., He, S., Mackie, I., Brandon, N. J., Marquis, K. L., Day, M., Hurko, O., McCaig, C. D., Riedel, G. & St Clair, D., 22 Oct 2008, In : Journal of Neuroscience. 28, 43, p. 10893-10904 12 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)
2007

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., Ouwehand, W. H., Samani, N. J., Todd, J. A., Donnelly, P., Barrett, J. C., Davison, D., Easton, D., Evans, D., Leung, H-T., Marchini, J. L., Morris, A. P., Spencer, C. C. A. & 31 others, Tobin, M. D., Attwood, A. P., Boorman, J. P., Cant, B., Everson, U., Hussey, J. M., Jolley, J. D., Knight, A. S., Koch, K., Meech, E., Nutland, S., Prowse, C. V., Stevens, H. E., Taylor, N. C., Walters, G. R., Walker, N. M., Watkins, N. A., Winzer, T., Jones, R. W., McArdle, W. L., Ring, S. M., Strachan, D. P., Pembrey, M., Breen, G., St Clair, D., Caesar, S., Gordon-Smith, K., Jones, L., Fraser, C., Green, E. K. & Biol RA Genet & Genom Study Syndicate, Wellcome Trust Case Control Consortium, Breast Canc Susceptib Collaborat, 7 Jun 2007, In : Nature. 447, 7145, p. 661-678 18 p.

Research output: Contribution to journalLiterature review

7075 Citations (Scopus)

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

Nejentsev, S., Howson, J. M. M., Walker, N. M., Szeszko, J., Field, S. F., Stevens, H. E., Reynolds, P., Hardy, M., King, E., Masters, J., Hulme, J., Maier, L. M., Smyth, D., Bailey, R., Cooper, J. D., Ribas, G., Campbell, R. D., Clayton, D. G., Todd, J. A., Burton, P. R. & 191 others, Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., Ouwehand, W. H., Samani, N. J., Donnelly, P., Barrett, J. C., Davison, D., Easton, D., Evans, D., Leung, H. T., Marchini, J. L., Morris, A. P., Spencer, C. C. A., Tobin, M. D., Attwood, A. P., Boorman, J. P., Cant, B., Everson, U., Hussey, J. M., Jolley, J. D., Knight, A. S., Koch, K., Meech, E., Nutland, S., Prowse, C. V., Taylor, N. C., Walters, G. R., Watkins, N. A., Winzer, T., Jones, R. W., McArdle, W. L., Ring, S. M., Strachan, D. P., Pembrey, M., Breen, G., St Clair, D., Caesar, S., Gordon-Smith, K., Jones, L., Fraser, C., Green, E. K., Grozeva, D., Hamshere, M. L., Holmans, P. A., Jones, I. R., Kirov, G., Moskvina, V., Nikolov, I., O'Donovan, M. C., Owen, M. J., Collier, D. A., Elkin, A., Farmer, A., Williamson, R., McGuffin, P., Young, A. H., Ferrier, I. N., Ball, S. G., Balmforth, A. J., Barrett, J. H., Bishop, D. T., Iles, M. M., Maqbool, A., Yuldasheva, N., Hall, A. S., Braund, P. S., Dixon, R. J., Mangino, M., Stevens, S., Thompson, J. R., Bredin, F., Tremelling, M., Parkes, M., Drummond, H., Lees, C. W., Nimmo, E. R., Satsangi, J., Fisher, S. A., Forbes, A., Lewis, C. M., Onnie, C. M., Prescott, N. J., Sanderson, J., Mathew, C. G., Barbour, J., Mohiuddin, M. K., Todhunter, C. E., Mansfield, J. C., Tariq, A., Cummings, F. R., Jewell, D. P., Webster, J., Brown, M. J., Lathrop, G. M., Connell, J., Dominiczak, A., Braga Marcano, C. A., Burke, B., Dobson, R., Gungadoo, J., Lee, K. L., Munroe, P. B., Newhouse, S. J., Onipinla, A., Wallace, C., Xue, M., Caulfield, M., Farrall, M., Barton, A., Bruce, I. N., Donovan, H., Eyre, S., Gilbert, P. D., Hider, S. L., Hinks, A. M., John, S. L., Potter, C., Silman, A. J., Symmons, D. P. M., Thomson, W., Worthington, J., Dunger, D. B., Widmer, B., Frayling, T. M., Freathy, R. M., Lango, H., Perry, J. R. B., Shields, B. M., Weedon, M. N., Hattersley, A. T., Hitman, G. A., Walker, M., Elliott, K. S., Groves, C. J., Lindgren, C. M., Rayner, N. W., Timpson, N. J., Zeggini, E., Newport, M., Sirugo, G., Lyons, E., Vannberg, F., Hill, A. V. S., Bradbury, L. A., Farrar, C., Pointon, J. J., Wordsworth, P., Brown, M. A., Franklyn, J. A., Heward, J. M., Simmonds, M. J., Gough, S. C. L., Seal, S., Stratton, M. R., Rahman, N., Ban, M., Goris, A., Sawcer, S. J., Compston, A., Conway, D., Jallow, M., Rockett, K. A., Bryan, C., Bumpstead, S. J., Chaney, A., Downes, K., Ghori, J., Gwilliam, R., Hunt, S. E., Inouye, M., Keniry, A., King, E., McGinnis, R., Potter, S., Ravindrarajah, R., Whittaker, P., Withers, D., Cardin, N. J., Ferreira, T., Pereira-Gale, J., Hallgrimsdóttir, I. B., Howie, B. N., Su, Z., Yik, Y. T., Vukcevic, D., Bentley, D. & Compston, A., 6 Dec 2007, In : Nature. 450, 7171, p. 887-892 6 p.

Research output: Contribution to journalArticle

379 Citations (Scopus)

LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia

Francks, C., Maegawa, S., Laurén, J., Abrahams, B. S., Velayos-Baeza, A., Medland, S. E., Colella, S., Groszer, M., McAuley, E. Z., Caffrey, T. M., Timmusk, T., Pruunsild, P., Koppel, I., Lind, P. A., Matsumoto-Itaba, N., Nicod, J., Xiong, L., Joober, R., Enard, W., Krinsky, B. & 22 others, Nanba, E., Richardson, A. J., Riley, B. P., Martin, N. G., Strittmatter, S. M., Möller, H-J., Rujescu, D., St Clair, D., Muglia, P., Roos, J. L., Fisher, S. E., Wade-Martins, R., Rouleau, G. A., Stein, J. F., Karayiorgou, M., Geschwind, D. H., Ragoussis, J., Kendler, K. S., Airaksinen, M. S., Oshimura, M., DeLisi, L. E. & Monaco, A. P., Dec 2007, In : Molecular Psychiatry. 12, 12, p. 1129-1139 11 p.

Research output: Contribution to journalArticle

240 Citations (Scopus)

LRRTM1 protein is located in the endoplasmic reticulum (ER) in mammalian cells

Francks, C., Maegawa, S., Laurén, J., Abrahams, B. S., Velayos-Baeza, A., Medland, S. E., Colella, S., Groszer, M., McAuley, E. Z., Caffrey, T. M., Timmusk, T., Pruunsild, P., Koppel, I., Lind, P. A., Matsumoto-Itaba, N., Nicod, J., Xiong, L., Joober, R., Enard, W., Krinsky, B. & 22 others, Nanba, E., Richardson, A. J., Riley, B. P., Martin, N. G., Strittmatter, S. M., Möller, H. J., Rujescu, D., St. Clair, D., Muglia, P., Roos, J. L., Fisher, S. E., Wade-Martins, R., Rouleau, G. A., Stein, J. F., Karayiorgou, M., Geschwind, D. H., Ragoussis, J., Kendler, K. S., Airaksinen, M. S., Oshimura, M., Delisi, L. E. & Monaco, A. P., 1 Dec 2007, In : Molecular Psychiatry. 12, 1 p., 1057.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Visual scan paths in first-episode schizophrenia and cannabis-induced psychosis

Benson, P. J., Leonards, U., Lothian, R. M., St Clair, D. M. & Merlo, M. C. G., 1 Jul 2007, In : Journal of Psychiatry and Neuroscience. 32, 4, p. 267-274 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2006

An association study between the transthyretin (TTR) gene and mental retardation

Li, J., Gao, J. J., Zhang, F. C., Xing, Q. H., Dang, F. L., Gao, X. C., Duan, S. W., Zheng, Z. J., Qian, X. Q., Qin, W., Li, X. W., Han, Y. F., Li, J., Feng, G. Y., St Clair, D. M. & He, L., 2006, In : European Archives of Psychiatry and Clinical Neuroscience. 256, 4, p. 230-235 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)