David Stead

Research output

Research output per year 2003 2008 2011 2012 2018 2019 2020 2022 2024

• 34 Article
• 1 Published conference contribution
• 1 Abstract
• 1 Letter

Research output per year

Research output per year

Search results

• 2024

  A nematode-specific ribonucleoprotein complex mediates interactions between the major nematode spliced leader snRNP and its target pre-mRNAs

  Eijlers, P., Al-Khafaji, M. I., Soto Martin, E., Fasimoye, R. Y., Stead, D., Wenzel, M., Müller, B. M. & Pettitt, J., 12 Apr 2024, (Accepted/In press) In: Nucleic Acids Research.

  Research output: Contribution to journal › Article › peer-review
• 2022

  Nature of b-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation

  de Assis, L. J., Bain, J. M., Liddle, C., Leaves, I., Hacker, C., da Silva, R. P., Yuecel, R., Bebes, A., Stead, D., Childers, D. S., Pradhan, A., Mackenzie, K., Lagree, K., Larcombe, D. E., Ma, Q., Avelar, G. M., Netea, M. G., Erwig, L. P., Mitchell, A. P., Brown, G. D., & 2 othersGow, N. A. R. & Brown, A. J. P., 20 Dec 2022, In: mBio. 13, 6, 19 p., e02605-22.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucans 100%
  • Cell Wall 76%
  • Candida albicans 75%
  • Cyclic AMP-Dependent Protein Kinases 20%
  • Pathogen-Associated Molecular Pattern Molecules 20%
  7 Citations (Scopus)

  4 Downloads (Pure)

• Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS

  Bakke, F. K., Gundappa, M. K., Matz, H., Stead, D. A., Macqueen, D. J. & Dooley, H., 6 Jun 2022, In: Frontiers in Immunology. 13, 15 p., 873390.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sharks 100%
  • Tandem Mass Spectrometry 76%
  • Nurses 50%
  • Transcriptome 27%
  • Proteomics 27%
  6 Citations (Scopus)

  1 Downloads (Pure)

• Biomarkers of caspofungin resistance in Candida albicans isolates: A proteomic approach

  Buda de Cesare, G., Hafez, A., Stead, D., Llorens, C. & Munro, C., 2022, In: Virulence. 13, 1, p. 1005-1018 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • caspofungin 100%
  • Caspofungin 88%
  • Candida albicans 67%
  • echinocandins 66%
  • Cell Wall 64%
  6 Citations (Scopus)
• 2020

  Plasma proteome responses in salmonid fish following immunization

  Bakke, F. K., Monte, M. M., Stead, D. A., Causey, D. R., Douglas, A., Macqueen, D. J. & Dooley, H., 8 Oct 2020, In: Frontiers in Immunology. 11, p. 1-20 20 p., 581070.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Salmonidae 100%
  • hen egg lysozyme 79%
  • Egg White 73%
  • Proteome 71%
  • Fishes 63%
  9 Citations (Scopus)

  7 Downloads (Pure)

• Addition of Broad Bean Hull to Wheat Flour for the Development of High-Fiber Bread: Effects on Physical and Nutritional Properties

  Ni, Q., Ranawana, V., Hayes, H., Hayward, N., Stead, D. & Raikos, V., 25 Sept 2020, In: Foods. 9, 9, 15 p., 1192.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Flour 100%
  • Bread 96%
  • Triticum 91%
  • faba beans 82%
  • wheat flour 78%
  33 Citations (Scopus)

  8 Downloads (Pure)

• β-glucan is a major growth substrate for human gut bacteria related to Coprococcus eutactus

  Alessi, A. M., Gray, V., Farquharson, F. M., Flores-López, A., Shaw, S., Stead, D., Wegmann, U., Shearman, C., Gasson, M., Collie-Duguid, E. SR., Flint, H. J. & Louis, P., 1 Jun 2020, In: Environmental Microbiology. 22, 6, p. 2150-2164 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Coprococcus eutactus 100%
  • Glucans 58%
  • glucans 46%
  • Glycoside Hydrolases 44%
  • (1-6)-alpha-glucomannan 44%
  20 Citations (Scopus)

  8 Downloads (Pure)

• Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat

  Johansson, H. K. L., Svingen, T., Boberg, J., Fowler, P. A., Stead, D., Vinggaard, A. M. & Filis, P., Apr 2020, In: Archives of Toxicology. 94, p. 1241-1250 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Calbindin 2 100%
  • Endocrine Disruptors 95%
  • Endocrine Disruptor 91%
  • Paracetamol 89%
  • Marker 65%
  8 Citations (Scopus)

  10 Downloads (Pure)

• Interaction of whey protein with polyphenols from salal fruits (Gaultheria shallon) and the effects on protein structure and hydrolysis pattern by Flavourzyme®

  Ni, H., Hayes, H., Stead, D., Liu, G., Yang, H., Li, H. & Raikos, V., 1 Mar 2020, In: International Journal of Food Science and Technology. 55, 3, p. 1281-1288 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gaultheria 100%
  • flavourzyme 92%
  • Gaultheria shallon 85%
  • Polyphenols 80%
  • Whey 70%
  10 Citations (Scopus)

  5 Downloads (Pure)
• 2019

  Angiotensin‐converting enzyme inhibitory activity of hydrolysates generated from whey protein fortified with salal fruits (Galtheria shallon) by enzymatic treatment with Pronase from Streptomyces griseus

  Raikos, V., Hayes, H., Stead, D. & Ni, H., Nov 2019, In: International Journal of Food Science and Technology. 54, 11, p. 2975-2982 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Streptomyces griseus 100%
  • Enzyme activity 94%
  • Lactalbumin 87%
  • Whey Proteins 83%
  • Pronase 79%
  6 Citations (Scopus)

  5 Downloads (Pure)

• Long-term, proteome-scale analysis of rainbow trout immune proteins: Implications for aquaculture vaccine development

  Bakke, F. K., Monte, M. M., Causey, D., Cornulier, T., Douglas, A., Stead, D., Martin, S. A. M., Macqueen, D. J. & Dooley, H., Aug 2019, In: Fish & Shellfish Immunology. 91, p. 453 1 p.

  Research output: Contribution to journal › Abstract › peer-review

  • Aquaculture 100%
  • Oncorhynchus mykiss 94%
  • vaccine 92%
  • vaccine development 92%
  • rainbow 83%

• Proteomic comparison of selective breeding and growth hormone transgenesis in fish: Unique pathways to enhanced growth

  Causey, D. R., Kim, J-H., Stead, D. A., Martin, S. A. M., Devlin, R. H. & Macqueen, D. J., 10 Feb 2019, In: Journal of Proteomics. 192, p. 114-124 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Selective Breeding 100%
  • Growth Hormone 81%
  • Gene Transfer Techniques 81%
  • Proteomics 58%
  • Fishes 58%
  26 Citations (Scopus)

  7 Downloads (Pure)
• 2018

  High-throughput proteomic profiling of the fish liver following bacterial infection

  Causey, D. R., Pohl, M. A. N., Stead, D. A., Martin, S. A. M., Secombes, C. J. & MacQueen, D., 1 Oct 2018, In: BMC Genomics. 19, 17 p., 719.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aeromonas salmonicida 100%
  • Bacterial Infections 86%
  • Proteomics 85%
  • Fishes 85%
  • Oncorhynchus mykiss 59%
  66 Citations (Scopus)

  10 Downloads (Pure)

• Incorporating salal berry (Gaultheria shallon) and blackcurrant (Ribes nigrum) pomace in yogurt for the development of a beverage with antidiabetic properties

  Ni, H., Hayes, H. E., Stead, D. & Raikos, V., Oct 2018, In: Heliyon. 4, 10, 00875.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gaultheria 100%
  • Ribes 78%
  • Yogurt 66%
  • Glucosidases 58%
  • Beverages 56%
  27 Citations (Scopus)

  10 Downloads (Pure)

• Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs

  Herrero de Dios, C., Day, A. M., Tillmann, A. T., Kastora, S. L., Stead, D., Salgado, P. S., Quinn, J. & Brown, A. J. P., 27 Mar 2018, In: mBio. 9, 2, 16 p., e02229-17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nitrosative Stress 100%
  • Mitogen-Activated Protein Kinases 72%
  • Oxidation-Reduction 70%
  • Phosphorylation 50%
  • Phosphotransferases 34%
  23 Citations (Scopus)

  8 Downloads (Pure)
• 2017

  Postprandial hepatic protein expression in trout Oncorhynchus mykiss a proteomics examination

  Mente, E., Pierce, G. J., Antonopoulou, E., Stead, D. A. & Martin, SAM., Mar 2017, In: Biochemistry and Biophysics Reports . 9, p. 79-85 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Trout 100%
  • Oncorhynchus mykiss 96%
  • Proteomics 69%
  • Meals 56%
  • Liver 39%
  10 Citations (Scopus)

  13 Downloads (Pure)
• 2016

  Combination antimicrobial susceptibility testing of Burkholderia cepacia complex: significance of species

  Abbott, F. K., Milne, K. E. N., Stead, D. A. & Gould, I. M., Nov 2016, In: International Journal of Antimicrobial Agents. 48, 5, p. 521-527 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Burkholderia cepacia complex 100%
  • Tobramycin 31%
  • Burkholderia cenocepacia 20%
  • Burkholderia 18%
  • Sulfamethoxazole 17%
  11 Citations (Scopus)

• The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

  Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M. & Brown, A. J. P., 13 Apr 2016, In: PLoS Pathogens. 12, 4, 26 p., 1005566.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • ubiquitination 100%
  • Ubiquitination 86%
  • Carbon 78%
  • Virulence 69%
  • Candida albicans 67%
  60 Citations (Scopus)

  10 Downloads (Pure)
• 2013

  Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events

  Potrykus, J., Stead, D., Maccallum, D. M., Urgast, D. S., Raab, A., van Rooijen, N., Feldmann, J. & Brown, A. J. P., 17 Oct 2013, In: PLoS Pathogens. 9, 10, 12 p., e1003676.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • candidiasis 100%
  • Candidiasis 81%
  • Iron 58%
  • iron 51%
  • immunity 22%
  46 Citations (Scopus)

  10 Downloads (Pure)
• 2012

  The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans

  Sandai, D., Yin, Z., Selway, L., Stead, D., Walker, J., Leach, M. D., Bohovych, I., Ene, I. V., Kastora, S., Budge, S., Munro, C. A., Odds, F. C., Gow, N. A. R. & Brown, A. J. P., 11 Dec 2012, In: mBio. 3, 6, 12 p., e00495-12.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ubiquitination 100%
  • Candida albicans 93%
  • Carbon 90%
  • Yeasts 74%
  • Saccharomyces cerevisiae 37%
  85 Citations (Scopus)

  9 Downloads (Pure)

• Survey of the camel urinary proteome by shotgun proteomics using a multiple database search strategy

  Alhaider, A. A., Bayoumi, N., Argo, E., Gader, A. G. M. A. & Stead, D. A., Nov 2012, In: Proteomics. 12, 22, p. 3403-3406 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Camelus 100%
  • Firearms 79%
  • Proteome 72%
  • Proteomics 64%
  • Databases 42%
  17 Citations (Scopus)

• Quantitative proteomic analysis of yeast DNA replication proteins

  Kubota, T., Stead, D. A., Hiraga, S., ten Have, S. & Donaldson, A. D., Jun 2012, In: Methods. 57, 2, p. 196-202 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroxyurea 100%
  • Stable Isotope 75%
  • DNA Replication 68%
  • Proteomics 63%
  • Chromatin 60%
  17 Citations (Scopus)

• Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans

  Leach, M. D., Stead, D. A., Argo, E., MacCallum, D. M. & Brown, A. J. P., May 2012, In: Molecular Microbiology. 84, 3, p. 594 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitination 100%
  • Candida albicans 93%
  • Proteomics 84%
  • Virulence 80%
  1 Citation (Scopus)
• 2011

  A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease

  Mukhopadhya, I., Hansen, R., Nicholl, C. E., Alhaidan, Y. A., Thomson, J. M., Berry, S. H., Pattinson, C., Stead, D. A., Russell, R. K., El-Omar, E. M. & Hold, G. L., 31 Oct 2011, In: PloS ONE. 6, 10, 10 p., e27076.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Inflammatory Bowel Diseases 100%
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry 31%
  • Ulcerative Colitis 26%
  • Electron Scanning Microscopy 25%
  • Proteomics 24%
  67 Citations (Scopus)

  10 Downloads (Pure)

• Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans

  Leach, M. D., Stead, D. A., Argo, E. & Brown, A. J. P., 1 Mar 2011, In: Molecular Biology of the Cell. 22, 5, p. 687-702 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sumoylation 100%
  • Candida albicans 74%
  • Growth 37%
  • Proteomics 19%
  • Chaperonin 60 15%
  49 Citations (Scopus)

  10 Downloads (Pure)

• Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans

  Leach, M. D., Stead, D. A., Argo, E. A., MacCallum, D. M. & Brown, A. J. P., Mar 2011, In: Molecular Microbiology. 79, 6, p. 1574-1593 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ubiquitination 100%
  • Candida albicans 93%
  • Proteomics 84%
  • Virulence 80%
  • Polyubiquitin 19%
  52 Citations (Scopus)

  9 Downloads (Pure)
• 2010

  Impact of the transcriptional regulator, Ace2, on the Candida glabrata secretome

  Stead, D. A., Walker, J., Holcombe, L. J., Gibbs, S. R. S., Yin, Z., Selway, L., Butler, G., Brown, A. J. P. & Haynes, K., Jan 2010, In: Proteomics. 10, 2, p. 212-223 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Candida glabrata 100%
  • Protein 30%
  • Proteins 20%
  • Proteome 19%
  • Cell Wall 18%
  21 Citations (Scopus)
• 2009

  A proteomic analysis of the salt, cadmium and peroxide stress responses in Candida albicans and the role of the Hog1 stress-activated MAPK in regulating the stress-induced proteome

  Yin, Z., Stead, D., Walker, J., Selway, L., Smith, D. A., Brown, A. J. P. & Quinn, J., Oct 2009, In: Proteomics. 9, 20, p. 4686-4703 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Salt Stress 100%
  • Cadmium Salt 93%
  • Peroxides 77%
  • Cadmium 69%
  • Proteome 63%
  50 Citations (Scopus)
• 2008

  MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans

  Ramsdale, M., Selway, L., Stead, D. A., Walker, J., Yin, Z., Nicholls, S. M., Crowe, J. D., Brown, A. J. P. & Sheils, E. M., Oct 2008, In: Molecular Biology of the Cell. 19, 10, p. 4393-4403 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Candida albicans 100%
  • Acids 74%
  • Response Elements 17%
  • Microarray Analysis 17%
  • Saccharomyces cerevisiae 15%
  63 Citations (Scopus)

• Guidelines for reporting the use of gel electrophoresis in proteomics

  Gibson, F., Anderson, L., Babnigg, G., Baker, M., Binz, P. . A., Borthwick, A., Cash, P., Day, B. W., Friedman, D. B., Garland, D., Gutstein, H. B., Hoogland, C., Jones, N. A., Khan, A., Klose, J., Lamond, A. I., Lemkin, P. F., Lilley, K. S., Minden, J., Morris, N. J., & 9 othersPaton, N. W., Pisano, M. R., Prime, J. E., Rabilloud, T., Stead, D. A., Taylor, C. F., Voshol, H., Wipat, A. & Jones, A. R., Aug 2008, In: Nature Biotechnology. 26, 8, p. 863-864 1 p.

  Research output: Contribution to journal › Letter › peer-review
  48 Citations (Scopus)

• Information quality in proteomics

  Stead, D. A., Paton, N. W., Missier, P., Embury, S. M., Hedeler, C., Jin, B., Brown, A. J. P. & Preece, A., 1 Mar 2008, In: Briefings in Bioinformatics. 9, 2, p. 174-188 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics 100%
  • Data Accuracy 39%
  • Proteins 34%
  • Data Curation 28%
  • Information Management 24%
  29 Citations (Scopus)
• 2006

  Universal metrics for quality assessment of protein identifications by mass spectrometry

  Stead, D. A., Preece, A. D. & Brown, A. J. P., 2006, In: Molecular and Cellular Proteomics. 5, p. 1205-1211 6 p.

  Research output: Contribution to journal › Article › peer-review

  38 Citations (Scopus)
• 2005

  Managing information quality in e-science: A case study in proteomics

  Missier, P., Preece, A., Embury, S., Jin, B. L., Greenwood, M., Stead, D. & Brown, A., 2005, Perspectives in Conceptual Modeling. ER 2005. Springer , p. 423-432 10 p. (Lecture Notes in Computer Science; vol. 3770).

  Research output: Chapter in Book/Report/Conference proceeding › Published conference contribution

  • e-Science 100%
  • Proteomics 93%
  • Ontology 59%
  6 Citations (Scopus)

• Proteomic changes associated with inactivation of the Candida glabrata ACE2 virulence-moderating gene

  Stead, D. A., Findon, H., Yin, Z., Walker, J., Selway, L., Cash, P., Dujon, B., Hennequin, C., Brown, A. J. P. & Haynes, K., 2005, In: Proteomics. 5, p. 1838-1848 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Candida glabrata 100%
  • Proteomics 68%
  • Virulence 64%
  • Two Dimensional Polyacrylamide Gel Electrophoresis 43%
  • Protein Synthesis 38%
  19 Citations (Scopus)
• 2004

  PEDRo: A database for storing, searching and disseminating experimental proteomics data

  Garwood, K., McLaughlin, T., Garwood, C., Joens, S., Morrison, N., Taylor, C. F., Carroll, K., Evans, C., Whetton, A. D., Hart, S., Stead, D., Yin, Z., Brown, A. J. P., Hesketh, A., Chater, K., Hansson, L., Mewissen, M., Ghazal, P., Howard, J., Lilley, K. S., & 5 othersGaskell, S. J., Brass, A., Hubbard, S. J., Oliver, S. G. & Paton, N. W., 17 Sept 2004, In: BMC Genomics. 5, 11 p., 68.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Proteomics 100%
  • Databases 65%
  • Datasets 57%
  • Proteome 56%
  • Data Management 24%
  61 Citations (Scopus)

  12 Downloads (Pure)

• Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae

  Yin, Z., Stead, D. A., Selway, L., Walker, J., Riba-Garcia, I., McInerney, T., Gaskell, S., Oliver, S. G., Cash, P. & Brown, A. J. P., 2004, In: Proteomics. 4, 8, p. 2425-2436 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Starvation 100%
  • Candida albicans 93%
  • Saccharomyces cerevisiae 85%
  • Proteomics 84%
  • Amitrole 72%
  81 Citations (Scopus)
• 2003

  A systematic approach to modeling, capturing, and disseminating proteomics experimental data

  Taylor, C. F., Paton, N. W., Garwood, K. L., Kirby, P. D., Stead, D. A., Yin, Z., Deutsch, E., Selway, L., Walker, J., Riba-Garcia, I., Mohammed, S., Deery, M., Howard, J., Dunkley, T., Aebersold, R., Kell, D., Lilley, A., Roepstorff, P., Yates, J. R., Brass, A., & 5 othersBrown, A. J. P., Cash, P., Gaskell, S., Hubbard, S. & Oliver, S. G., Mar 2003, In: Nature Biotechnology. 21, 3, p. 247-254 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics 100%
  • Microarrays 81%
  • XML 43%
  • Proteome 31%
  • Proteins 27%
  229 Citations (Scopus)