• 539 Citations
20082019
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Research Output 2008 2019

  • 539 Citations
  • 12 Article
  • 1 Abstract
  • 1 Poster
  • 1 Literature review
2019
1 Citation (Scopus)

Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion

Pradhan, A., Avelar, G. M., Bain, J. M., Childers, D., Pelletier, C., Larcombe, D. E., Shekhova, E., Netea, M. G., Brown, G. D., Erwig, L., Gow, N. A. R. & Brown, A. J. P., 22 Nov 2019, In : Nature Communications. 10, 5315.

Research output: Contribution to journalArticle

Open Access
File
Immune Evasion
Glucans
pathogens
Cell Wall
Iron
2018
14 Citations (Scopus)
13 Downloads (Pure)

Hypoxia promotes immune evasion by triggering β-glucan masking on the Candida albicans cell surface via mitochondrial and cAMP-protein kinase A signalling

Pradhan, A., Avelar, G., Bain, J. M., Childers, D., Larcombe, D. E., Netea, M. G., Shekhova, E., Munro, C. A., Brown, G. D., Erwig, L., Gow, N. A. R. & Brown, A. J. P., 2018, In : mBio. 9, e01318-18.

Research output: Contribution to journalArticle

Open Access
File
Immune Evasion
Glucans
Mitochondrial Proteins
Cyclic AMP-Dependent Protein Kinases
Candida albicans
2016
18 Citations (Scopus)
6 Downloads (Pure)

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

MacKie, J., Szabo, E. K., Urgast, D. S., Ballou, E. R., Childers, D. S., MacCallum, D. M., Feldmann, J. & Brown, A. J. P., 30 Jun 2016, In : PloS ONE. 11, 6, 0158683.

Research output: Contribution to journalArticle

Open Access
File
Candida
Micronutrients
Candida albicans
dietary minerals
Poisoning
54 Citations (Scopus)
10 Downloads (Pure)

Lactate signalling regulates fungal β-glucan masking and immune evasion

Ballou, E., M. Avelar, G., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L., Erwig, L. P., Munro, C. A., Gow, N. A. R., Brown, G. D., MacCallum, D. M. & Brown, A. J. P., 12 Dec 2016, In : Nature Microbiology. 2, 16238.

Research output: Contribution to journalArticle

Open Access
File
Immune Evasion
Glucans
Candida albicans
Lactic Acid
Fungi
26 Citations (Scopus)
5 Downloads (Pure)

The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M. & Brown, A. J. P., 13 Apr 2016, In : PLoS Pathogens. 12, 4, p. 1-26 26 p., 1005566.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitination
Virulence
Candida albicans
Carbon
Yeasts
2015
11 Citations (Scopus)
Open Access
File
Candida
response elements
Response Elements
Candida albicans
Virulence
2014
24 Citations (Scopus)

A 5′ UTR-mediated Translational Efficiency Mechanism Inhibits the Candida albicans Morphological Transition

Childers, D. S., Mundodi, V., Banerjee, M. & Kadosh, D., May 2014, In : Molecular Microbiology. 92, 3, p. 570-585 16 p.

Research output: Contribution to journalArticle

5' Untranslated Regions
Candida albicans
Virulence
Biological Phenomena
Polyribosomes
25 Citations (Scopus)
4 Downloads (Pure)

Conflicting interests in the pathogen-host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity

Potrykus, J., Ballou, E. R., Childers, D. S. & Brown, A. J. P., 13 Mar 2014, In : PLoS Pathogens. 10, 3, 4 p., e1003910.

Research output: Contribution to journalLiterature review

Open Access
File
Micronutrients
Immunity
Fungi
Nutritional Physiological Phenomena
Trace Elements

New Clox systems for rapid and efficient gene disruption in Candida albicans

Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R. & Brown, A. J. P., Mar 2014.

Research output: Contribution to conferenceAbstract

New Clox systems for rapid and efficient gene disruption in Candida albicans

Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R. & Brown, A. J. P., Mar 2014.

Research output: Contribution to conferencePoster

16 Citations (Scopus)
3 Downloads (Pure)

New Clox Systems for rapid and efficient gene disruption in Candida albicans

Shahana, S., Childers, D. S., Ballou, E. R., Bohovych, I., Odds, F. C., Gow, N. A. R. & Brown, A. J. P., 18 Jun 2014, In : PloS ONE. 9, 6, 10 p., e100390.

Research output: Contribution to journalArticle

Open Access
File
Candida
gene targeting
Candida albicans
Genes
Recycling
110 Citations (Scopus)
4 Downloads (Pure)

Stress adaptation in a pathogenic fungus

Brown, A. J. P., Budge, S., Kaloriti, D., Tillmann, A., Jacobsen, M. D., Yin, Z., Ene, I. V., Bohovych, I., Sandai, D., Kastora, S., Potrykus, J., Ballou, E. R., Childers, D. S., Shahana, S. & Leach, M. D., 1 Jan 2014, In : Journal of Experimental Biology. 217, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Open Access
File
Candida albicans
Fungi
fungus
fungi
yeast
2013
23 Citations (Scopus)

Comparative evolution of morphological regulatory functions in Candida species

Lackey, E., Vipulanandan, G., Childers, D. S. & Kadosh, D., Oct 2013, In : Eukaryotic Cell. 12, 10, p. 1356-1368 13 p.

Research output: Contribution to journalArticle

Candida albicans
Candida
Virulence
Aptitude
Regulator Genes
2011
84 Citations (Scopus)

Coevolution of morphology and virulence in Candida species

Childers, D. S. T., Carlisle, P. L. & Kadosh, D., Sep 2011, In : Eukaryotic Cell. 10, 9, p. 1173-1182 10 p.

Research output: Contribution to journalArticle

Candida
Virulence
Fungi
Gene Expression
Research
2008
133 Citations (Scopus)
4 Downloads (Pure)

UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence

Banerjee, M., Thompson, D. S., Lazzell, A., Carlisle, P. L., Pierce, C., Monteagudo, C., López-Ribot, J. L. & Kadosh, D., 1 Apr 2008, In : Molecular Biology of the Cell. 19, 4, p. 1354-1365 12 p.

Research output: Contribution to journalArticle

Open Access
File
Candida albicans
Virulence
Gene Expression
Aptitude
Growth