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Research Output

2020
Open Access
2019

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 1 Jun 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
7 Downloads (Pure)

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1172.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
1 Downloads (Pure)

Erratum to: Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis (Nature Communications, (2018), 9, 1, (5288), 10.1038/s41467-018-07738-1)

Rudkin, F. M., Raziunaite, I., Workman, H., Essono, S., Belmonte, R., MacCallum, D. M., Johnson, E. M., Silva, L., Palma, A. S., Feizi, T., Jensen, A., Erwig, L. P. & Gow, N. A. R., 18 Jan 2019, In : Nature Communications. 10, 394.

Research output: Contribution to journalComment/debate

Open Access

Inhibition of classical and alternative modes of respiration in Candida albicans leads to cell wall remodelling and increased macrophage recognition

Duvenage, L., Walker, L. A., Bojarczuk, A., Johnston, S. A., MacCallum, D. M., Munro, C. A. & Gourlay, C. W., 29 Jan 2019, In : mBio. 10, 1, e02535-18.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
6 Downloads (Pure)
2018

Oxford Textbook of Medical Mycology

Kibbler, C. C. (ed.), Barton, R. (ed.), Gow, N. (ed.), Howell, S. (ed.), MacCallum, D. (ed.) & Manuel, R. (ed.), 2018, Oxford University Press. 400 p. (Oxford Textbooks in Infectious Disease and Microbiology)

Research output: Book/ReportBook

Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis

Rudkin, F. M., Raziunaite, I., Workman, H., Essono, S., Belmonte, R., MacCallum, D. M., Johnson, E. M., Silva, L. M., Palma, A. S., Feizi, T., Jensen, A., Erwig, L. P. & Gow, N. A. R., 11 Dec 2018, In : Nature Communications. 9, 5288.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
5 Downloads (Pure)

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

Dambuza, I. M., Drake, T., Chapuis, A., Zhou, X., Correia, J., Taylor-Smith, L., Legrave, N., Rasmussen, T., Fisher, M. C., Bicanic, T., Harrison, T. S., Jaspars, M., May, R. C., Brown, G. D., Yuecel, R., MacCallum, D. M. & Ballou, E., 18 May 2018, In : PLoS Pathogens. 14, 5, p. 1-28 28 p., e1006978.

Research output: Contribution to journalArticle

Open Access
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33 Citations (Scopus)
9 Downloads (Pure)
2017

Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

Sherrington, S. L., Sorsby, E., Mahtey, N., Kumwenda, P., Lenardon, M., Brown, I., Ballou, E., MacCallum, D. M. & Hall, R. A., 2017, In : PLoS Pathogens. 13, 5, e1006403.

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
8 Downloads (Pure)

Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation

Day, A. M., Smith, D. A., Ikeh, M. A. C., Haider, M., Herrero De Dios, C. M., Brown, A. J. P., Morgan, B. A., Erwig, L. P., MacCallum, D. M. & Quinn, J., 2017, In : PLoS Pathogens. 13, 1, p. 1-27 27 p., e1006131.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
7 Downloads (Pure)

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions

Wagener, J., MacCallum, D. M., Brown, G. D., Gow, N. A. R. & Doering, T. L. (ed.), 24 Jan 2017, In : mBio. 8, 1, e01820-16.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
8 Downloads (Pure)

Elevated catalase expression in a fungal pathogen is a double-edged sword of iron

Pradhan, A., Herrero De Dios, C., Belmonte, R., Budge, S., Lopez Garcia, A., Kolmogorova, A., LEE, K. K., Martin, B. D., Ribeiro, A., Bebes, A., Yuecel, R., Gow, N. A. R., Munro, C. A., MacCallum, D. M., Quinn, J. & Brown, A. J. P., 22 May 2017, In : PLoS Pathogens. 13, 5, p. 1-25 25 p., 1006405.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
6 Downloads (Pure)

Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen

Day, A. M., Herrero de Dios, C., MacCallum, D. M., Brown, A. J. P. & Quinn, J., 2017, In : Scientific Reports. 7, p. 1-10 10 p., 14340.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
5 Downloads (Pure)
2016

Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp

Liu, Z., Moran, G. P., Sullivan, D. J., MacCallum, D. M. & Myers, L. C., 31 Oct 2016, In : PLoS Genetics. 12, 10, e1006373.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
5 Downloads (Pure)

Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

MacKie, J., Szabo, E. K., Urgast, D. S., Ballou, E. R., Childers, D. S., MacCallum, D. M., Feldmann, J. & Brown, A. J. P., 30 Jun 2016, In : PloS ONE. 11, 6, 0158683.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
7 Downloads (Pure)

Lactate signalling regulates fungal β-glucan masking and immune evasion

Ballou, E., M. Avelar, G., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L., Erwig, L. P., Munro, C. A., Gow, N. A. R., Brown, G. D., MacCallum, D. M. & Brown, A. J. P., 12 Dec 2016, In : Nature Microbiology. 2, 16238.

Research output: Contribution to journalArticle

Open Access
File
60 Citations (Scopus)
11 Downloads (Pure)

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

Ikeh, M. A. C., Kastora, S. L., Day, A. M., Herrero-de-Dios, C. M., Tarrant, E., Waldron, K. J., Banks, A. P., Bain, J. M., Lydall, D., Veal, E. A., MacCallum, D. M., Erwig, L. P., Brown, A. J. P. & Quinn, J., 1 Sep 2016, In : Molecular Biology of the Cell. 27, 17, p. 2784-2801 18 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
11 Downloads (Pure)

The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M. & Brown, A. J. P., 13 Apr 2016, In : PLoS Pathogens. 12, 4, p. 1-26 26 p., 1005566.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
6 Downloads (Pure)
2015

Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity

Vautier, S., Drummond, R. A., Chen, K., Murray, G. I., Kadosh, D., Brown, A. J. P., Gow, N. A. R., MacCallum, D. M., Kolls, J. K. & Brown, G. D., Apr 2015, In : Cellular Microbiology. 17, 4, p. 445-450 6 p.

Research output: Contribution to journalArticle

Open Access
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27 Citations (Scopus)
6 Downloads (Pure)

Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans

Tillmann, A. T., Strijbis, K., Cameron, G., Radmaneshfar, E., Thiel, M., Munro, C. A., MacCallum, D. M., Distel, B., Gow, N. A. R. & Brown, A. J. P., 3 Jun 2015, In : PloS ONE. 10, 6, 24 p., e0126940.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
6 Downloads (Pure)
2014

A novel renal epithelial cell in vitro assay to assess Candida albicans virulence

Szabo, E. K. & MacCallum, D. M., 28 Feb 2014, In : Virulence. 5, 2, p. 1-11 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

Whibley, N., Maccallum, D. M., Vickers, M. A., Zafreen, S., Waldmann, H., Hori, S., Gaffen, S. L., Gow, N. A. R., Barker, R. N. & Hall, A. M., Apr 2014, In : European Journal of Immunology. 44, 4, p. 1069-1083 15 p.

Research output: Contribution to journalArticle

Open Access
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26 Citations (Scopus)
7 Downloads (Pure)

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation

Wagener, J., Malireddi, R. K. S., Lenardon, M. D., Köberle, M., Vautier, S., Maccallum, D. M., Biedermann, T., Schaller, M., Netea, M. G., Kanneganti, T-D., Brown, G. D., Brown, A. J. P. & Gow, N. A. R., 10 Apr 2014, In : PLoS Pathogens. 10, 4, 15 p., e1004050.

Research output: Contribution to journalArticle

Open Access
File
124 Citations (Scopus)
4 Downloads (Pure)

Murine model for Fusarium oxysporum invasive fusariosis reveals organ-specific structures for dissemination and long-term persistence

Schafer, K., Di Pietro, A., Gow, N. A. R. & MacCallum, D., 27 Feb 2014, In : PloS ONE. 9, 2, 9 p., e89920.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
6 Downloads (Pure)
2013

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1

Marakalala, M. J., Vautier, S., Potrykus, J., Walker, L. A., Shepardson, K. M., Hopke, A., Mora-Montes, H. M., Lee, K., Kerrigan, A., Netea, M. G., Murray, G. I., Maccallum, D. M., Wheeler, R., Munro, C. A., Gow, N. A. R., Cramer, R. A., Brown, A. J. P. & Brown, G. D., 2013, In : PLoS Pathogens. 9, 4, 12 p., e1003315.

Research output: Contribution to journalArticle

Open Access
File
112 Citations (Scopus)
5 Downloads (Pure)
7 Citations (Scopus)

Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events

Potrykus, J., Stead, D., Maccallum, D. M., Urgast, D. S., Raab, A., van Rooijen, N., Feldmann, J. & Brown, A. J. P., 17 Oct 2013, In : PLoS Pathogens. 9, 10, 12 p., e1003676.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
6 Downloads (Pure)

Mouse Model of Invasive Fungal Infection

MacCallum, D. M., 2013, Mouse Models of Innate Immunity: Methods and Protocols. Allen, I. C. (ed.). Totowa: Humana Press, p. 145-153 9 p. 17. (Methods in Molecular Biology; vol. 1031).

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)

Role of the Candida albicans MNN1 gene family in cell wall structure and virulence

Bates, S., Hall, R. A., Cheetham, J., Netea, M. G., Maccallum, D. M., Brown, A. J. P., Odds, F. C. & Gow, N. A. R., 26 Jul 2013, In : BMC Research Notes. 6, p. 1-9 9 p., 294.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
5 Downloads (Pure)

The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans

Hall, R. A., Bates, S., Lenardon, M. D., Maccallum, D. M., Wagener, J., Lowman, D. W., Kruppa, M. D., Williams, D. L., Odds, F. C., Brown, A. J. P. & Gow, N. A. R., 25 Apr 2013, In : PLoS Pathogens. 9, 4, 16 p., e1003276.

Research output: Contribution to journalArticle

Open Access
File
62 Citations (Scopus)
16 Downloads (Pure)

Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape

Patterson, M. J., MacKenzie, C. G., Smith, D. A., da Silva Dantas, A., Sherston, S., Veal, E. A., Morgan, B. A., MacCallum, D. M., Erwig, L. P. & Quinn, J., Dec 2013, In : Antioxidants & Redox Signaling. 19, 18, p. 2244-2260 17 p.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
6 Downloads (Pure)
2012

A new in vitro model of host-fungus interaction

Szabo, E. K. & MacCallum, D. M., Jun 2012, In : Mycoses. 55, s4, p. 299-299 1 p.

Research output: Contribution to journalAbstract

Candida albicans evades protective immunity by promoting the expansion of induced CD4(+) CD25(+) FoxP3(+) Helioslo regulatory T cells that enhance Th17 responses

Whibley, N. W., MacCallum, D. M., Vickers, M. A., Waldmann, H., Hori, S., Gow, N. A. R., Barker, R. N. & Hall, A. M., Sep 2012, In : Immunology. 137, s1, p. 206-206 1 p.

Research output: Contribution to journalAbstract

53 Citations (Scopus)

C-type lectin receptors and cytokines in fungal immunity

Vautier, S., Maccallum, D. M. & Brown, G. D., Apr 2012, In : Cytokine. 58, 1, p. 89-99 10 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Cytokine Measurement Using Cytometric Bead Arrays

Castillo-Barahona, L. C. & MacCallum, D. M., 2012, Host-Fungus Interactions: Methods and Protocols. Brand, A. C. & MacCallum, D. M. (eds.). Humana Press, Vol. 845. p. 425-434 10 p. (Methods in Molecular Biology; vol. 845, no. 6).

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Dectin-1 is not required for controlling Candida albicans colonisation of the gastrointestinal tract

Vautier, S., Drummond, R. A., Redelinghuys, P., Murray, G. I., Maccallum, D. M. & Brown, G. D., Dec 2012, In : Infection and Immunity. 80, 12, p. 4216-4222 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Echinocandin resistance due to simultaneous FKS mutation and increased cell wall chitin in a Candida albicans bloodstream isolate following brief exposure to caspofungin

Imtiaz, T., Lee, K. K., Munro, C. A., Maccallum, D. M., Shankland, G. S., Johnson, E. M., Macgregor, M. S. & Bal, A. M., Sep 2012, In : Journal of Medical Microbiology. 61, 9, p. 1330-1334 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo

Lee, K. K., Maccallum, D. M., Jacobsen, M. D., Walker, L. A., Odds, F. C., Gow, N. A. R. & Munro, C. A., Jan 2012, In : Antimicrobial Agents and Chemotherapy. 56, 1, p. 208-217 10 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

Ene, I. V., Adya, A., Wehmeier, S., Brand, A., MacCallum, D. M., Gow, N. A. R. & Brown, A. J. P., Sep 2012, In : Cellular Microbiology. 14, 9, p. 1319-1335 17 p.

Research output: Contribution to journalArticle

Open Access
File
135 Citations (Scopus)
5 Downloads (Pure)

Host carbon sources modulate cell wall architecture and virulence in Candida albicans

Ene, I. V., Adya, A. K., Heilmann, C. J., Sorgo, A. G., Klis, F. M., MacCallum, D. M., Gow, N. A. & Brown, A. J. P., Jun 2012, In : Mycoses. 55, s4, p. 172-173 2 p.

Research output: Contribution to journalArticle

Hosting Infection: Experimental Models to Assay Candida Virulence

MacCallum, D. M., 2012, In : International Journal of Microbiology. 2012, 12 p., 363764.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
5 Downloads (Pure)

Mouse Intravenous Challenge Models and Applications

MacCallum, D. M., 2012, Host-Fungus Interactions: Methods and Protocols. Brand, A. C. & MacCallum, D. M. (eds.). Humana Press, Vol. 845. p. 499-509 11 p. (Methods in Molecular Biology; vol. 845, no. 8).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

State of the art: Mouse models of invasive candidiasis

MacCallum, D. M., Jun 2012, In : Mycoses. 55, s4, p. 10-11 2 p., B3.

Research output: Contribution to journalAbstract

Ypd1-mediated two-component signalling in Candida albicans

Smith, D. A., MacCallum, D. M., Morgan, B. A. & Quinn, J., Jun 2012, In : Mycoses. 55, s4, p. 15-15 1 p.

Research output: Contribution to journalAbstract

2011

Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans

Nicholls, S., MacCallum, D. M., Kaffarnik, F. A. R., Selway, L., Peck, S. C. & Brown, A. J. P., Mar 2011, In : Fungal Genetics and Biology. 48, 3, p. 297-305 9 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
6 Downloads (Pure)

A three day mouse model of Candida albicans infection outcome

MacCallum, D. M. & Odds, F., 2011, In : Mycoses. 54, Suppl. 2, p. 112 1 p.

Research output: Contribution to journalAbstract

Candida albicans induces the expansion of regulatory helper T cells in healthy humans

Whibley, N., Ormerod, A. D., MacCallum, D. M., Gow, N. A. R., Barker, R. N. & Hall, A. M., Dec 2011, In : Immunology. 135, Suppl. 1, p. 157 1 p., 397.

Research output: Contribution to journalAbstract

Candida albicans promotes the differentiation of induced CD4(+) CD25(+) Foxp3(+) regulatory T cells

Whibley, N., MacCallum, D. M., Vickers, M. A., Gow, N. A., Barker, R. N. & Hall, A. M., Dec 2011, In : Immunology. 135, Suppl. 1, p. 161 1 p.

Research output: Contribution to journalAbstract

11 Citations (Scopus)