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2020
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2019

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Chapuis, A. F., Ballou, E. R. & MacCallum, D. M., 1 Jun 2019, In : Journal of Fungi. 5, 2, 9 p., 29.

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2 Citations (Scopus)
7 Downloads (Pure)

An ex-vivo human skin model to study superficial fungal infections

Corzo-Leon, D. E., Munro, C. A. & MacCallum, D. M., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1172.

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6 Citations (Scopus)
2 Downloads (Pure)

Inhibition of classical and alternative modes of respiration in Candida albicans leads to cell wall remodelling and increased macrophage recognition

Duvenage, L., Walker, L. A., Bojarczuk, A., Johnston, S. A., MacCallum, D. M., Munro, C. A. & Gourlay, C. W., 29 Jan 2019, In : mBio. 10, 1, e02535-18.

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13 Citations (Scopus)
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2018

Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis

Rudkin, F. M., Raziunaite, I., Workman, H., Essono, S., Belmonte, R., MacCallum, D. M., Johnson, E. M., Silva, L. M., Palma, A. S., Feizi, T., Jensen, A., Erwig, L. P. & Gow, N. A. R., 11 Dec 2018, In : Nature Communications. 9, 5288.

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11 Citations (Scopus)
5 Downloads (Pure)

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

Dambuza, I. M., Drake, T., Chapuis, A., Zhou, X., Correia, J., Taylor-Smith, L., Legrave, N., Rasmussen, T., Fisher, M. C., Bicanic, T., Harrison, T. S., Jaspars, M., May, R. C., Brown, G. D., Yuecel, R., MacCallum, D. M. & Ballou, E., 18 May 2018, In : PLoS Pathogens. 14, 5, p. 1-28 28 p., e1006978.

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34 Citations (Scopus)
9 Downloads (Pure)
2017

Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

Sherrington, S. L., Sorsby, E., Mahtey, N., Kumwenda, P., Lenardon, M., Brown, I., Ballou, E., MacCallum, D. M. & Hall, R. A., 2017, In : PLoS Pathogens. 13, 5, e1006403.

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49 Citations (Scopus)
8 Downloads (Pure)

Blocking two-component signalling enhances Candida albicans virulence and reveals adaptive mechanisms that counteract sustained SAPK activation

Day, A. M., Smith, D. A., Ikeh, M. A. C., Haider, M., Herrero De Dios, C. M., Brown, A. J. P., Morgan, B. A., Erwig, L. P., MacCallum, D. M. & Quinn, J., 2017, In : PLoS Pathogens. 13, 1, p. 1-27 27 p., e1006131.

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10 Citations (Scopus)
7 Downloads (Pure)

Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions

Wagener, J., MacCallum, D. M., Brown, G. D., Gow, N. A. R. & Doering, T. L. (ed.), 24 Jan 2017, In : mBio. 8, 1, e01820-16.

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31 Citations (Scopus)
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Elevated catalase expression in a fungal pathogen is a double-edged sword of iron

Pradhan, A., Herrero De Dios, C., Belmonte, R., Budge, S., Lopez Garcia, A., Kolmogorova, A., LEE, K. K., Martin, B. D., Ribeiro, A., Bebes, A., Yuecel, R., Gow, N. A. R., Munro, C. A., MacCallum, D. M., Quinn, J. & Brown, A. J. P., 22 May 2017, In : PLoS Pathogens. 13, 5, p. 1-25 25 p., 1006405.

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13 Citations (Scopus)
6 Downloads (Pure)

Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen

Day, A. M., Herrero de Dios, C., MacCallum, D. M., Brown, A. J. P. & Quinn, J., 2017, In : Scientific Reports. 7, p. 1-10 10 p., 14340.

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5 Citations (Scopus)
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2016

Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp

Liu, Z., Moran, G. P., Sullivan, D. J., MacCallum, D. M. & Myers, L. C., 31 Oct 2016, In : PLoS Genetics. 12, 10, e1006373.

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7 Citations (Scopus)
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Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections

MacKie, J., Szabo, E. K., Urgast, D. S., Ballou, E. R., Childers, D. S., MacCallum, D. M., Feldmann, J. & Brown, A. J. P., 30 Jun 2016, In : PloS ONE. 11, 6, 0158683.

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24 Citations (Scopus)
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Lactate signalling regulates fungal β-glucan masking and immune evasion

Ballou, E., M. Avelar, G., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L., Erwig, L. P., Munro, C. A., Gow, N. A. R., Brown, G. D., MacCallum, D. M. & Brown, A. J. P., 12 Dec 2016, In : Nature Microbiology. 2, 16238.

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64 Citations (Scopus)
11 Downloads (Pure)

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

Ikeh, M. A. C., Kastora, S. L., Day, A. M., Herrero-de-Dios, C. M., Tarrant, E., Waldron, K. J., Banks, A. P., Bain, J. M., Lydall, D., Veal, E. A., MacCallum, D. M., Erwig, L. P., Brown, A. J. P. & Quinn, J., 1 Sep 2016, In : Molecular Biology of the Cell. 27, 17, p. 2784-2801 18 p.

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19 Citations (Scopus)
11 Downloads (Pure)

The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

Childers, D. S., Raziunaite, I., Mol Avelar, G., Mackie, J., Budge, S., Stead, D., Gow, N. A. R., Lenardon, M. D., Ballou, E. R., MacCallum, D. M. & Brown, A. J. P., 13 Apr 2016, In : PLoS Pathogens. 12, 4, p. 1-26 26 p., 1005566.

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30 Citations (Scopus)
6 Downloads (Pure)
2015

Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity

Vautier, S., Drummond, R. A., Chen, K., Murray, G. I., Kadosh, D., Brown, A. J. P., Gow, N. A. R., MacCallum, D. M., Kolls, J. K. & Brown, G. D., Apr 2015, In : Cellular Microbiology. 17, 4, p. 445-450 6 p.

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27 Citations (Scopus)
6 Downloads (Pure)

Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans

Tillmann, A. T., Strijbis, K., Cameron, G., Radmaneshfar, E., Thiel, M., Munro, C. A., MacCallum, D. M., Distel, B., Gow, N. A. R. & Brown, A. J. P., 3 Jun 2015, In : PloS ONE. 10, 6, 24 p., e0126940.

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17 Citations (Scopus)
6 Downloads (Pure)
2014

A novel renal epithelial cell in vitro assay to assess Candida albicans virulence

Szabo, E. K. & MacCallum, D. M., 28 Feb 2014, In : Virulence. 5, 2, p. 1-11 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

Whibley, N., Maccallum, D. M., Vickers, M. A., Zafreen, S., Waldmann, H., Hori, S., Gaffen, S. L., Gow, N. A. R., Barker, R. N. & Hall, A. M., Apr 2014, In : European Journal of Immunology. 44, 4, p. 1069-1083 15 p.

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27 Citations (Scopus)
7 Downloads (Pure)

Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation

Wagener, J., Malireddi, R. K. S., Lenardon, M. D., Köberle, M., Vautier, S., Maccallum, D. M., Biedermann, T., Schaller, M., Netea, M. G., Kanneganti, T-D., Brown, G. D., Brown, A. J. P. & Gow, N. A. R., 10 Apr 2014, In : PLoS Pathogens. 10, 4, 15 p., e1004050.

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128 Citations (Scopus)
4 Downloads (Pure)

Murine model for Fusarium oxysporum invasive fusariosis reveals organ-specific structures for dissemination and long-term persistence

Schafer, K., Di Pietro, A., Gow, N. A. R. & MacCallum, D., 27 Feb 2014, In : PloS ONE. 9, 2, 9 p., e89920.

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9 Citations (Scopus)
6 Downloads (Pure)
2013

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1

Marakalala, M. J., Vautier, S., Potrykus, J., Walker, L. A., Shepardson, K. M., Hopke, A., Mora-Montes, H. M., Lee, K., Kerrigan, A., Netea, M. G., Murray, G. I., Maccallum, D. M., Wheeler, R., Munro, C. A., Gow, N. A. R., Cramer, R. A., Brown, A. J. P. & Brown, G. D., 2013, In : PLoS Pathogens. 9, 4, 12 p., e1003315.

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114 Citations (Scopus)
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9 Citations (Scopus)

Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events

Potrykus, J., Stead, D., Maccallum, D. M., Urgast, D. S., Raab, A., van Rooijen, N., Feldmann, J. & Brown, A. J. P., 17 Oct 2013, In : PLoS Pathogens. 9, 10, 12 p., e1003676.

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33 Citations (Scopus)
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Role of the Candida albicans MNN1 gene family in cell wall structure and virulence

Bates, S., Hall, R. A., Cheetham, J., Netea, M. G., Maccallum, D. M., Brown, A. J. P., Odds, F. C. & Gow, N. A. R., 26 Jul 2013, In : BMC Research Notes. 6, p. 1-9 9 p., 294.

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18 Citations (Scopus)
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The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicans

Hall, R. A., Bates, S., Lenardon, M. D., Maccallum, D. M., Wagener, J., Lowman, D. W., Kruppa, M. D., Williams, D. L., Odds, F. C., Brown, A. J. P. & Gow, N. A. R., 25 Apr 2013, In : PLoS Pathogens. 9, 4, 16 p., e1003276.

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64 Citations (Scopus)
16 Downloads (Pure)

Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape

Patterson, M. J., MacKenzie, C. G., Smith, D. A., da Silva Dantas, A., Sherston, S., Veal, E. A., Morgan, B. A., MacCallum, D. M., Erwig, L. P. & Quinn, J., Dec 2013, In : Antioxidants & Redox Signaling. 19, 18, p. 2244-2260 17 p.

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48 Citations (Scopus)
6 Downloads (Pure)
2012

C-type lectin receptors and cytokines in fungal immunity

Vautier, S., Maccallum, D. M. & Brown, G. D., Apr 2012, In : Cytokine. 58, 1, p. 89-99 10 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Dectin-1 is not required for controlling Candida albicans colonisation of the gastrointestinal tract

Vautier, S., Drummond, R. A., Redelinghuys, P., Murray, G. I., Maccallum, D. M. & Brown, G. D., Dec 2012, In : Infection and Immunity. 80, 12, p. 4216-4222 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Echinocandin resistance due to simultaneous FKS mutation and increased cell wall chitin in a Candida albicans bloodstream isolate following brief exposure to caspofungin

Imtiaz, T., Lee, K. K., Munro, C. A., Maccallum, D. M., Shankland, G. S., Johnson, E. M., Macgregor, M. S. & Bal, A. M., Sep 2012, In : Journal of Medical Microbiology. 61, 9, p. 1330-1334 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo

Lee, K. K., Maccallum, D. M., Jacobsen, M. D., Walker, L. A., Odds, F. C., Gow, N. A. R. & Munro, C. A., Jan 2012, In : Antimicrobial Agents and Chemotherapy. 56, 1, p. 208-217 10 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

Ene, I. V., Adya, A., Wehmeier, S., Brand, A., MacCallum, D. M., Gow, N. A. R. & Brown, A. J. P., Sep 2012, In : Cellular Microbiology. 14, 9, p. 1319-1335 17 p.

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139 Citations (Scopus)
5 Downloads (Pure)

Host carbon sources modulate cell wall architecture and virulence in Candida albicans

Ene, I. V., Adya, A. K., Heilmann, C. J., Sorgo, A. G., Klis, F. M., MacCallum, D. M., Gow, N. A. & Brown, A. J. P., Jun 2012, In : Mycoses. 55, s4, p. 172-173 2 p.

Research output: Contribution to journalArticle

Hosting Infection: Experimental Models to Assay Candida Virulence

MacCallum, D. M., 2012, In : International Journal of Microbiology. 2012, 12 p., 363764.

Research output: Contribution to journalArticle

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47 Citations (Scopus)
5 Downloads (Pure)
2011

Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans

Nicholls, S., MacCallum, D. M., Kaffarnik, F. A. R., Selway, L., Peck, S. C. & Brown, A. J. P., Mar 2011, In : Fungal Genetics and Biology. 48, 3, p. 297-305 9 p.

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50 Citations (Scopus)
6 Downloads (Pure)
11 Citations (Scopus)

Identification of a novel response regulator, Crr1, that is required for hydrogen peroxide resistance in Candida albicans

Bruce, C. R., Smith, D. A., Rodgers, D., da Silva Dantas, A., MacCallum, D. M., Morgan, B. A. & Quinn, J., 2 Dec 2011, In : PloS ONE. 6, 12, 10 p., e27979.

Research output: Contribution to journalArticle

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6 Citations (Scopus)
4 Downloads (Pure)

MAPKKK-Independent regulation of the Hog1 stress activated protein kinase in Candida albicans

Cheetham, J., MacCallum, D. M., Doris, K. S., da Silva Dantas, A., Scorfield, S., Odds, F., Smith, D. A. & Quinn, J., 9 Dec 2011, In : The Journal of Biological Chemistry. 286, p. 42002-42016 15 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
Open Access
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35 Citations (Scopus)
6 Downloads (Pure)

Wild-type Drosophila melanogaster as an alternative model system for investigating the pathogenicity of Candida albicans

Glittenberg, M. T., Silas, S., MacCallum, D. M., Gow, N. A. R. & Ligoxygakis, P., Jul 2011, In : Disease Models & Mechanisms. 4, 4, p. 504-514 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2010

a multicenter collaborative study for the standardization of Candida albicans genotyping using a polymorphic microsatellite marker

Garcia-Hermoso, D., MacCallum, D. M., Lott, T., Sampaio, P., Buitrago Serna, M-J., Grenouillet, F., Klaassen, C. & Bretagne, S., Jul 2010, In : Journal of Clinical Microbiology. 48, 7, p. 2578-2581 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

CO2 acts as a signalling molecule in populations of the fungal pathogen Candida albicans

Hall, R., De Sordi, L., MacCallum, D. M., Topal, H., Eaton, R., Bloor, J. W., Robinson, G. K., Levin, L. R., Buck, J., Wang, Y., Gow, N. A. R., Steegborn, C. & Muehlschlegel, F. A., 18 Nov 2010, In : PLoS Pathogens. 6, 11, 11 p., e1001193.

Research output: Contribution to journalArticle

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77 Citations (Scopus)
4 Downloads (Pure)

Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model

Spiering, M. J., Moran, G. P., Chauvel, M., MacCallum, D. M., Higgins, J., Hokamp, K., Yeomans, T., d'Enfert, C., Coleman, D. C. & Sullivan, J., Feb 2010, In : Eukaryotic Cell. 9, 2, p. 251-265 15 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans

Vieira, N., Casal, M., Johansson, B., MacCallum, D. M., Brown, A. J. P. & Paiva, S., Mar 2010, In : Molecular Microbiology. 75, 6, p. 1337-1354 18 p.

Research output: Contribution to journalArticle

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33 Citations (Scopus)
3 Downloads (Pure)

Genetic dissection of azole resistance mechanisms in Candida albicansand their validation in a mouse model of disseminated infection

MacCallum, D. M., Coste, A., Ischer, F., Jacobsen, M. D., Odds, F. C. & Sanglard, D., Apr 2010, In : Antimicrobial Agents and Chemotherapy. 54, 4, p. 1476-1483 8 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans

da Silva Dantas, A., Patterson, M. J., Smith, D. A., MacCallum, D. M., Erwig, L. P., Morgan, B. A. & Quinn, J., Oct 2010, In : Molecular and Cellular Biology. 30, 19, p. 4550-4563 14 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
2009

Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney

Walker, L. A., MacCallum, D. M., Bertram, G., Gow, N. A. R., Odds, F. C. & Brown, A. J. P., Feb 2009, In : Fungal Genetics and Biology. 46, 2, p. 210-219 10 p.

Research output: Contribution to journalArticle

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62 Citations (Scopus)
53 Downloads (Pure)

Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress

Enjalbert, B., Moran, G. P., Vaughan, C., Yeomans, T., MacCallum, D. M., Quinn, J., Coleman, D. C., Brown, A. J. P. & Sullivan, D. J., Apr 2009, In : Molecular Microbiology. 72, 1, p. 216-228 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)