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George David McIlroy

Dr

    • AB25 2ZD

    • 249 Citations
    20102018
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    Fingerprint Dive into the research topics where George David McIlroy is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 44 Similar Profiles
    Fenretinide Medicine & Life Sciences
    Retinoids Medicine & Life Sciences
    Obesity Medicine & Life Sciences
    High Fat Diet Medicine & Life Sciences
    Adipocytes Medicine & Life Sciences
    Adipose Tissue Medicine & Life Sciences
    Congenital Generalized Lipodystrophy Medicine & Life Sciences
    Drosophila Medicine & Life Sciences

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    Research Output 2010 2018

    • 249 Citations
    • 10 Article
    • 2 Abstract
    3 Citations (Scopus)
    9 Downloads (Pure)

    Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

    McIlroy, G. D., Suchacki, K., Roelofs, A. J., Yang, W., Fu, Y., Bai, B., Wallace, R. J., de Bari, C., Cawthorn, W. P., Han, W., Delibegovic, M. & Rochford, J. J., Apr 2018, In : Molecular Metabolism. 10, p. 55-65 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Congenital Generalized Lipodystrophy
    Metabolic Diseases
    Adipocytes
    High Fat Diet
    Lipodystrophy
    5 Downloads (Pure)
    Open Access
    File
    High Fat Diet
    Knockout Mice
    Adipose Tissue
    Lipodystrophy
    Congenital Generalized Lipodystrophy
    12 Citations (Scopus)
    12 Downloads (Pure)

    Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

    Morrice, N., McIlroy, G. D., Tammireddy, S., Reekie, J., Shearer, K. D., Doherty, M. K., Delibegovic, M., Whitfield, P. D. & Mody, N., 3 Mar 2017, In : Scientific Reports. 7, 43782 .

    Research output: Contribution to journalArticle

    Open Access
    File
    Fenretinide
    Retinoids
    Insulin
    Liver
    Homeostasis
    16 Citations (Scopus)
    6 Downloads (Pure)

    Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

    McIlroy, G. D., Tammireddy, S. R., Maskrey, B. H., Grant, L., Doherty, M. K., Watson, D. G., Delibegovic, M., Whitfield, P. D. & Mody, N., 15 Jan 2016, In : Biochemical Pharmacology. 100, p. 86-97 12 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Fenretinide
    Adipogenesis
    Retinoic Acid Receptors
    Ceramides
    Biosynthesis