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Research Output 1999 2017

  • 1057 Citations
  • 31 Article
  • 1 Literature review
2017
2 Citations (Scopus)
3 Downloads (Pure)

PEA‐15 (Phosphoprotein Enriched in Astrocytes 15) Is a Protective Mediator in the Vasculature and Is Regulated During Neointimal Hyperplasia

Greig, F. H., Kennedy, S., Gibson, G., Ramos, J. W. & Nixon, G. F., 11 Sep 2017, In : Journal of the American Heart Association. 6, 9, p. 1-15 15 p., e006936.

Research output: Contribution to journalArticle

Open Access
File
Phosphoproteins
Astrocytes
Hyperplasia
Vascular Smooth Muscle
Smooth Muscle Myocytes
2016
1 Citation (Scopus)
8 Downloads (Pure)

Sphingosylphosphorylcholine inhibits macrophage adhesion to vascular smooth muscle cells

Wirrig, C., McKean, J. S., Wilson, H. M. & Nixon, G. F., 1 Sep 2016, In : Biochemical Pharmacology. 115, p. 43-50 8 p.

Research output: Contribution to journalArticle

Open Access
File
Macrophages
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
Adhesion
2015
11 Citations (Scopus)
6 Downloads (Pure)

The cAMP-producing agonist beraprost inhibits human vascular smooth muscle cell migration via exchange protein directly activated by cAMP

McKean, J. S., Murray, F., Gibson, G., Shewan, D. A., Tucker, S. J. & Nixon, G. F., 1 Sep 2015, In : Cardiovascular Research. 107, 4, p. 546-555 10 p.

Research output: Contribution to journalArticle

Open Access
File
beraprost
Vascular Smooth Muscle
Cyclic AMP
Smooth Muscle Myocytes
Cell Movement
2014
13 Citations (Scopus)
6 Downloads (Pure)

Phosphoprotein enriched in astrocytes (PEA)-15: A potential therapeutic target in multiple disease states

Greig, F. H. & Nixon, G. F., Sep 2014, In : Pharmacology & Therapeutics. 143, 3, p. 265-274 10 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphoproteins
Astrocytes
Fas-Associated Death Domain Protein
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
2013
19 Citations (Scopus)

Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling

Alcantara, E. H., Shin, M. Y., Feldmann, J., Nixon, G. F., Beattie, J. H. & Kwun, I. S., 1 May 2013, In : Atherosclerosis. 228, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Zinc
Down-Regulation
Cell Proliferation
14 Citations (Scopus)

Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries

Allen-Redpath, K., Ou, O., Beattie, J. H., Kwun, I-S., Feldmann, J. & Nixon, G. F., 1 Aug 2013, In : Cardiovascular Research. 99, 3, p. 525–534 10 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Zinc
Arteries
Apoptosis
7 Citations (Scopus)

Plasma zinc's alter ego is a low-molecular-weight humoral factor

Ou, O., Allen-Redpath, K., Urgast, D., Gordon, M-J., Campbell, G., Feldmann, J., Nixon, G. F., Mayer, C-D., Kwun, I-S. & Beattie, J. H., Sep 2013, In : The FASEB Journal. 27, 9, p. 3672-3682 11 p.

Research output: Contribution to journalArticle

Ego
Zinc
Molecular Weight
Molecular weight
Plasmas
17 Citations (Scopus)

Sphingosine-1-phosphate-induced release of TIMP-2 from vascular smooth muscle cells inhibits angiogenesis

Mascall, K. S., Small, G. R., Gibson, G. & Nixon, G. F., 1 May 2012, In : Journal of Cell Science. 125, 9, p. 2267-2275 9 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-2
Vascular Smooth Muscle
Smooth Muscle Myocytes
Endothelial Cells
Intercellular Junctions
17 Citations (Scopus)

Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis

Beattie, J. H., Gordon, M-J., Duthie, S. J., McNeil, C. J., Horgan, G. W., Nixon, G. F., Feldmann, J. & Kwun, I-S., Jul 2012, In : Molecular Nutrition & Food Research. 56, 7, p. 1097-1105 9 p.

Research output: Contribution to journalArticle

atherogenesis
atherosclerosis
blood vessels
Blood Vessels
Zinc
2011
10 Citations (Scopus)

A phospholipase Cγ1-activated pathway regulates transcription in human vascular smooth muscle cells

Hunter, I., Mascall, K. S., Ramos, J. & Nixon, G. F., 1 Jun 2011, In : Cardiovascular Research. 90, 3, p. 557-564 8 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
Vascular Smooth Muscle
Smooth Muscle Myocytes
Astrocytes
14 Citations (Scopus)

Sphingosylphosphorylcholine is a proinflammatory mediator in cerebral arteries

Wirrig, C., Hunter, I., Mathieson, F. A. & Nixon, G. F., Jan 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 1, p. 212-221 9 p.

Research output: Contribution to journalArticle

Cerebral Arteries
Chemokine CCL2
Transcription Factors
Subarachnoid Hemorrhage
Inflammation
21 Citations (Scopus)

Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts

Alcantara, E. H., Lomeda, R-A. R., Feldmann, J., Nixon, G. F., Beattie, J. H. & Kwun, I-S., Oct 2011, In : Molecular Nutrition & Food Research. 55, 10, p. 1552-1560 9 p.

Research output: Contribution to journalArticle

2009
9 Citations (Scopus)
clopidogrel
Angioplasty
Aspirin
Smooth Muscle
Randomized Controlled Trials
143 Citations (Scopus)

Sphingolipids in inflammation: pathological implications and potential therapeutic targets

Nixon, G. F., Oct 2009, In : British Journal of Pharmacology. 158, 4, p. 982-993 12 p.

Research output: Contribution to journalArticle

Sphingolipids
Inflammation
Ceramides
Therapeutics
Cell Membrane
2008
22 Citations (Scopus)

Advanced glycation endproducts induce a proliferative response in vascular smooth muscle cells via altered calcium signaling

David, K. C., Scott, R. H. & Nixon, G. F., 30 Oct 2008, In : Biochemical Pharmacology. 76, 9, p. 1110-1120 11 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle

Kinnear, N. P., Wyatt, C. N., Clark, J. H., Calcraft, P. J., Fleischer, S., Jeyakumar, L. H., Nixon, G. F. & Evans, A. M., Aug 2008, In : Cell Calcium. 44, 2, p. 190-201 12 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
3 Downloads (Pure)

The multi-functional role of sphingosylphosphorylcholine

Nixon, G. F., Mathieson, F. A. & Hunter, I., 2008, In : Progress in Lipid Research. 47, p. 62-75 14 p.

Research output: Contribution to journalLiterature review

Open Access
File
2007
4 Citations (Scopus)

The potential roles of sphingolipids in vascular smooth-muscle function

Nixon, G. F., Mathieson, F. A. & Hunter, I., 2007, In : Biochemical Society Transactions. 35, 5, p. 908-909 2 p.

Research output: Contribution to journalArticle

2005
15 Citations (Scopus)

PDGF-induced signaling in proliferating and differentiated vascular smooth muscle: Effects of altered intracellular Ca2+ regulation

Egan, C. G., Wainwright, C., Wadsworth, R. M. & Nixon, G. F., Aug 2005, In : Cardiovascular Research. 67, 2, p. 308-316 8 p.

Research output: Contribution to journalArticle

2004
11 Citations (Scopus)
2003
25 Citations (Scopus)
84 Citations (Scopus)

Tumor necrosis factor-a-induced activation of RhoA in airway smooth muscle cells: Role in the Ca2+ sensitization of myosin light chain20 phosphorylation

Hunter, I., Cobban, H. J., Vandenabeele, P., MacEwan, D. J. & Nixon, G. F., Mar 2003, In : Molecular Pharmacology. 63, 3, p. 714-721 7 p.

Research output: Contribution to journalArticle

2002
106 Citations (Scopus)

Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction

Coussin, F., Scott, R. H., Wise, A. & Nixon, G. F., Jul 2002, In : Circulation Research. 91, 2, p. 151-157 6 p.

Research output: Contribution to journalArticle

2001
25 Citations (Scopus)

Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle

McFarlane, S. M., Jupp, O. J., Cobban, H. J., Hunter, I., Anderson, H. M., Vandenabeele, P., Nixon, G. F. & MacEwan, D. J., 2001, In : Biochemical Pharmacology. 61, 6, p. 749-759 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Thrombin-induced activation of RhoA in platelet shape change

Bodie, S. L., Ford, I., Greaves, M. & Nixon, G. F., 2001, In : Biochemical and Biophysical Research Communications. 287, 1, p. 71-76 5 p.

Research output: Contribution to journalArticle

2000
34 Citations (Scopus)
51 Citations (Scopus)

Expression and distribution of the type 1 and type 3 inositol 1,4,5-trisphosphate receptor in developing vascular smooth muscle

Tasker, P. N., Michelangeli, F. & Nixon, G. F., 1999, In : Circulation Research. 84, p. 536-542 7 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Tumour necrosis factor-alpha activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle

Parris, J. R. M., Cooban, H. J., Littlejohn, A. F., MacEwan, D. J. & Nixon, G. F., 1999, In : The Journal of Physiology. 518, p. 561-569 9 p.

Research output: Contribution to journalArticle