• 4933 Citations
20032020

Research output per year

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Research Output

  • 4933 Citations
  • 42 Article
  • 2 Abstract
  • 1 Other contribution
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Article
2020

Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin

Alnajjar, M., Barik, S. K., Bestwick, C., Campbell, F., Cruickshank, M., Farquharson, F., Holtrop, G., Horgan, G., Louis, P., Moar, K-M., Russell, W. R., Scobbie, L. & Hoggard, N., Jan 2020, In : Journal of Functional Foods. 64, 103597.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
6 Downloads (Pure)

Pivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystem

Wang, S. P., Rubio, L. A., Duncan, S. H., Donachie, G. E., Holtrop, G., Lo, G., Farquharson, F. M., Wagner, J., Parkhill, J., Louis, P., Walker, A. & Flint, H. J., 8 Sep 2020, In : mSystems.

Research output: Contribution to journalArticle

Open Access
2019

Dietary carbohydrate rather than protein intake drives colonic microbial fermentation during weight loss

Gratz, S. W., Hazim, S., Richardson, A. J., Scobbie, L., Johnstone, A. M., Fyfe, C., Holtrop, G., Lobley, G. E. & Russell, W. R., Apr 2019, In : European Journal of Nutrition. 58, 3, p. 1147-1158 12 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
4 Downloads (Pure)
2018
Open Access
File
2 Citations (Scopus)
26 Downloads (Pure)

Porcine small and large intestinal microbiota rapidly hydrolyze the masked mycotoxin deoxynivalenol-3-glucoside and release deoxynivalenol in spiked batch cultures in vitro

Gratz, S., Currie, V., Richardson, A., Duncan, G., Holtrop, G., Farquharson, F., Louis, P., Pinton, P. & Oswald, I. P., Jan 2018, In : Applied and Environmental Microbiology. 84, 2, p. 1-9 9 p., 02106-17.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
9 Downloads (Pure)

Specific substrate-driven changes in human faecal microbiota composition contrast with functional redundancy in short-chain fatty acid production

Reichardt, N., Vollmer, M., Holtrop, G., Farquharson, F. M., Wefers, D., Bunzel, M., Duncan, S. H., Drew, J. E., Williams, L. M., Milligan, G., Preston, T., Morrison, D., Flint, H. J. & Louis, P., 2018, In : The ISME Journal. 12, p. 610-622 13 p.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
13 Downloads (Pure)
2017

Masked trichothecene and zearalenone mycotoxins withstand digestion and absorption in the upper GI tract but are efficiently hydrolyzed by human gut microbiota in vitro

Gratz, S. W., Dinesh, R., Yoshinari, T., Holtrop, G., Richardson, A. J., Duncan, G., MacDonald, S., Lloyd, A. & Farbin, J., Apr 2017, In : Molecular Nutrition & Food Research. 61, 4, 1600680.

Research output: Contribution to journalArticle

Open Access
File
35 Citations (Scopus)
17 Downloads (Pure)
2016

Responses in whole-body amino acid kinetics to an acute, sub-clinical endotoxin challenge in lambs

Hoskin, S. O., Bremner, D. M., Holtrop, G. & Lobley, G. E., 28 Feb 2016, In : British Journal of Nutrition. 115, 4, p. 576-584 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Whole body and splanchnic amino acid metabolism in sheep during an acute endotoxin challenge

McNeil, C. J., Hoskin, S. O., Bremner, D. M., Holtrop, G. & Lobley, G. E., Jul 2016, In : British Journal of Nutrition. 116, 2, p. 211-222 12 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
8 Downloads (Pure)
2015

Modelling the emergent dynamics and major metabolites of the human colonic microbiota

Kettle, H., Louis, P. G. H., Holtrop, G., Duncan, S. H. & Flint, H. J., May 2015, In : Environmental Microbiology. 17, 5, p. 1615-1630 16 p.

Research output: Contribution to journalArticle

Open Access
File
53 Citations (Scopus)
5 Downloads (Pure)
14 Citations (Scopus)
2014
26 Citations (Scopus)

Glucose uptake by the brain on chronic high-protein weight-loss diets with either moderate or low amounts of carbohydrate

Lobley, G. E., Johnstone, A. M., Fyfe, C., Horgan, G. W., Holtrop, G., Bremner, D. M., Broom, I., Schweiger, L. & Welch, A., Feb 2014, In : British Journal of Nutrition. 111, 4, p. 586-597 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
20 Downloads (Pure)

Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

Salonen, A., Lahti, L., Salojärvi, J., Holtrop, G., Korpela, K., Duncan, S. H., Date, P., Farquharson, F., Johnstone, A. M., Lobley, G. E., Louis, P., Flint, H. J. & de Vos, W. M., Nov 2014, In : The ISME Journal. 8, 11, p. 2218-2230 13 p.

Research output: Contribution to journalArticle

232 Citations (Scopus)

Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes

Zhang, X., McGeoch, S. C., Megson, I. L., MacRury, S. M., Johnstone, A. M., Abraham, P., Pearson, D. W. M., De Roos, B., Holtrop, G., O'Kennedy, N. & Lobley, G. E., Jun 2014, In : Molecular Nutrition & Food Research. 58, 6, p. 1322-1332 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
8 Downloads (Pure)

Platelet-derived microparticle count and surface molecule expression differ between subjects with and without type 2 diabetes, independently of obesity status

Zhang, X., McGeoch, S. C., Johnstone, A. M., Holtrop, G., Sneddon, A. A., Macrury, S. M., Megson, I. L., Pearson, D. W. M., Abraham, P., De Roos, B., Lobley, G. E. & O'Kennedy, N., May 2014, In : Journal of Thrombosis and Thrombolysis. 37, 4, p. 455-463 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2013
Open Access
File
23 Citations (Scopus)
7 Downloads (Pure)
2012

Diet composition is associated with endogenous formation of N-nitroso compounds in obese men.

Holtrop, G., Johnstone, A. M., Fyfe, C. & Gratz, S. W., 1 Sep 2012, In : The Journal of Nutrition. 142, 9, p. 1652-1658 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Phylogenetic distribution of genes encoding β-glucuronidase activity in human colonic bacteria and the impact of diet on faecal glycosidase activities

McIntosh, F. M., Maison, N., Holtrop, G., Young, P., Stevens, V. J., Ince, J., Johnstone, A. M., Lobley, G., Flint, H. J. & Louis, P., 2012, In : Environmental Microbiology. 14, 8, p. 1876-1887 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

The effects of methyl-deficient diets on methionine and homocysteine metabolism in the pregnant rat

Wilson, F. A., Holtrop, G., Calder, A. G., Anderson, S. E., Lobley, G. E. & Rees, W., 15 Jun 2012, In : American Journal of Physiology: Endocrinology and Metabolism. 302, 12, p. E1531-E1540 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

Walker, A. W., Ince, J., Duncan, S. H., Webster, L., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., Louis, P., McIntosh, F., Johnstone, A. M., Lobley, G. E., Parkhill, J. & Flint, H. J., Feb 2011, In : The ISME Journal. 5, 2, p. 220-230 11 p.

Research output: Contribution to journalArticle

826 Citations (Scopus)

Food intake and dietary glycaemic index in free-living adults with and without type 2 diabetes mellitus

McGeoch, S. C., Holtrop, G., Fyfe, C., Lobley, G. E., Pearson, D. W. M., Abraham, P., Megson, I. L., Macrury, S. M. & Johnstone, A., Jun 2011, In : Nutrients. 3, 6, p. 683-693 11 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
5 Downloads (Pure)
339 Citations (Scopus)

Rates of production and utilization of lactate by microbial communities from the human colon

Belenguer, A., Holtrop, G., Duncan, S. H., Anderson, S. E., Calder, A. G., Flint, H. J. & Lobley, G. E., Jul 2011, In : FEMS Microbiology Ecology. 77, 1, p. 107-119 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2010
291 Citations (Scopus)
2009

Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii

Ramirez-Farias, C., Slezak, K., Fuller, Z., Duncan, A. S., Holtrop, G. & Louis, P., 28 Feb 2009, In : British Journal of Nutrition. 101, 4, p. 541-550 10 p.

Research output: Contribution to journalArticle

451 Citations (Scopus)

Fetal iron status regulates maternal iron metabolism during pregnancy in the rat

Gambling, L., Czopek, A., Andersen, H. S., Holtrop, G., Srai, S. K. S., Krejpcio, Z. & McArdle, H. J., 1 Apr 2009, In : American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 296, 4, p. R1063-R1070 8 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Tissue methionine cycle activity and homocysteine metabolism in female rats: impact of dietary methionine and folate plus choline

Wilson, F. A., van den Borne, J. J. G. C., Calder, A. G., O'Kennedy, N., Holtrop, G., Rees, W. & Lobley, G., Apr 2009, In : American Journal of Physiology: Endocrinology and Metabolism. 296, 4, p. E702-713 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2008

Contribution of gut microbial lysine to liver and milk amino acids in lactating does

Abecia, L., Balcells, J., Fondevila, M., Belenguer, A., Holtrop, G. & Lobley, G., Oct 2008, In : British Journal of Nutrition. 100, 5, p. 977-983 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Distribution of N-15 in amino acids during N-15-leucine infusion: impact on the estimation of endogenous flows in dairy cows

Lapierre, H., Ouellet, D. R., Berthiaume, R., Martineau, R., Holtrop, G. & Lobley, G. E., Jul 2008, In : Journal of Dairy Science. 91, 7, p. 2702-2714 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Human colonic microbiota associated with diet, obesity and weight loss

Duncan, S. H., Lobley, G., Holtrop, G., Ince, J., Johnstone, A., Louis, P. & Flint, H. J., Nov 2008, In : International Journal of Obesity. 32, 11, p. 1720-1724 5 p.

Research output: Contribution to journalArticle

697 Citations (Scopus)

The species composition of the human intestinal microbiota differs between particle-associated and liquid phase communities

Walker, A. W., Duncan, S. H., Harmsen, H. J. M., Holtrop, G., Welling, G. W. & Flint, H. J., Dec 2008, In : Environmental Microbiology. 10, 12, p. 3275-3283 9 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)
2007

Effect of dietary copper deficiency on iron metabolism in the pregnant rat

Andersen, H. S., Gambling, L., Holtrop, G. & McArdle, H. J., 1 Feb 2007, In : British Journal of Nutrition. 97, 2, p. 239-246 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Impact of pH on Lactate Formation and Utilization by Human Fecal Microbial Communities

Belenguer, A., Duncan, S. H., Holtrop, G., Anderson, S. E., Lobley, G. E. & Flint, H. J., Oct 2007, In : Applied and Environmental Microbiology. 73, 20, p. 6526-6533 8 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Reduced Dietary Intake of Carbohydrates by Obese Subjects Results in Decreased Concentrations of Butyrate and Butyrate-Producing Bacteria in Feces

Duncan, S. H., Belenguer, A., Holtrop, G., Johnstone, A. M., Flint, H. J. & Lobley, G. E., Feb 2007, In : Applied and Environmental Microbiology. 73, 4, p. 1073-1078 6 p.

Research output: Contribution to journalArticle

505 Citations (Scopus)

Selective colonization of insoluble substrates by human faecal bacteria

Leitch, E. C. M., Walker, A. W., Duncan, S. H., Holtrop, G. & Flint, H. J., Mar 2007, In : Environmental Microbiology. 9, 3, p. 667-679 13 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)

Maternal iron deficiency identifies critical windows for growth and cardiovascular development in the rat postimplantation embryo

Andersen, H. S., Gambling, L., Holtrop, G. & McArdle, H. J., May 2006, In : The Journal of Nutrition. 136, 5, p. 1171-1177 7 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut

Belenguer, A., Duncan, S. H., Calder, A. G., Holtrop, G., Louis, P., Lobley, G. & Flint, H. J., 1 May 2006, In : Applied and Environmental Microbiology. 72, 5, p. 3593-3599 7 p.

Research output: Contribution to journalArticle

408 Citations (Scopus)
2004

Contribution of acetate to butyrate formation by human faecal bacteria

Duncan, S. H., Holtrop, G., Lobley, G. E., Calder, A. G., Stewart, C. S. & Flint, H. J., Jun 2004, In : British Journal of Nutrition. 91, 6, p. 915-923 9 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)
2003

Effect of feed intake on amino acid transfers across the ovine hindquarters

Hoskin, S. O., Savary-Auzeloux, I. C., Calder, A. G., Zuur, G. & Lobley, G., 1 Feb 2003, In : British Journal of Nutrition. 89, 2, p. 167-179 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)