• 1404 Citations
1989 …2019
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Research Output 1989 2019

2019

Differential expression of CCR2 and CX3CR1 on CD16+ monocyte subsets is associated with asthma severity

Al-Rashoudi, R., Moir, G., Al-Hajjaj, M. S., Al-Alwan, M. M., Wilson, H. M. & Crane, I. J., 4 Nov 2019, In : Allergy, Asthma, and Clinical Immunology. 15, 64.

Research output: Contribution to journalArticle

Open Access
File
Monocytes
Asthma
Chemokine Receptors
Immune System Diseases
Flow Cytometry
8 Citations (Scopus)

Myocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy

Scally, C., Abbas, H., Ahearn, T., Srinivasan, J., Mezincescu, A., Rudd, A., Spath, N., Yucel-Finn, A., Yuecel, R., Oldroyd, K., Dospinescu, C., Horgan, G., Broadhurst, P., Henning, A., Newby, D. E., Semple, S., Wilson, H. M. & Dawson, D. K., 26 Mar 2019, In : Circulation. 139, 13, p. 1581-1592 12 p.

Research output: Contribution to journalArticle

Takotsubo Cardiomyopathy
Inflammation
Monocytes
Interleukin-6
Myocardium
2018
5 Citations (Scopus)
5 Downloads (Pure)

Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy

Wilson, H. M., Cheyne, L., Brown, P. A. J., Kerr, K., Hannah, A., Srinivasan, J., Duniak, N., Horgan, G. & Dawson, D. K., Dec 2018, In : JACC: Basic to Translational Science. 3, 6, p. 766-778 13 p.

Research output: Contribution to journalArticle

Open Access
File
Takotsubo Cardiomyopathy
Theoretical Models
Myocardium
Neutrophils
Heart Failure
5 Citations (Scopus)
6 Downloads (Pure)

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Le Sommer, S., Morrice, N., Pesaresi, M., Thompson, D., Vickers, M. A., Murray, G. I., Mody, N., Neel, B. G., Bence, K. K., Wilson, H. M. & Delibegovic, M., Jan 2018, In : Cancer Research. 78, 1, p. 75-87 13 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Tyrosine Phosphatases
Leukemia
Myeloid Cells
Acute Myeloid Leukemia
Liver
4 Downloads (Pure)

Gene expression data analysis identifies multiple deregulated pathways in patients with asthma

Alrashoudi, R. H., Crane, I. J., Wilson, H. M., Al-Alwan, M. & Alajez, N. M., Dec 2018, In : Bioscience Reports. 38, 6, BSR20180548.

Research output: Contribution to journalArticle

Open Access
File
Gene expression
Adrenal Cortex Hormones
Asthma
Gene Expression
Genes
4 Downloads (Pure)

Response to comment by Moxon et al

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Lees, E. K., Mody, N., Wilson, H. M. & Delibegovic, M., 2 Jan 2018, In : Clinical Science. 132, 1, p. 39-41 3 p.

Research output: Contribution to journalLetter

Open Access
File
2 Citations (Scopus)

Similarities and differences in surface receptor expression by THP-1 monocytes and differentiated macrophages polarized using seven different conditioning regimens

Forrester, M. A., Wassall, H. J., Hall, L. S., Cao, H., Wilson, H. M., Barker, R. N. & Vickers, M. A., Oct 2018, In : Cellular Immunology. 332, p. 58-76 19 p.

Research output: Contribution to journalArticle

Open Access
File
Monocytes
Macrophages
Sialic Acid Binding Immunoglobulin-like Lectins
C-Type Lectins
Scavenger Receptors
2017
4 Citations (Scopus)
11 Downloads (Pure)
Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
AMP-Activated Protein Kinases
Apolipoproteins E
Atherosclerotic Plaques
Interleukin-10
7 Citations (Scopus)
11 Downloads (Pure)
Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Atherosclerotic Plaques
Atherosclerosis
Pharmacology
Insulin Receptor
2016
11 Downloads (Pure)

Critical Role for Inflammatory Macrophages in Driving Antigen-dependent Th17 Cell Responses?

Arnold, C. E., Barker, R. N. & Wilson, H. M., 5 Apr 2016, In : Journal of Cytokine Biology. 1, 1, p. 1-3 3 p., 105.

Research output: Contribution to journalArticle

Open Access
File
Th17 Cells
Macrophages
Antigens
Helper-Inducer T-Lymphocytes
Macrophage Activation
17 Citations (Scopus)

Electric fields are novel determinants of human macrophage functions

Hoare, J. I., Rajnicek, A. M., McCaig, C. D., Barker, R. N. & Wilson, H. M., Jun 2016, In : Journal of Leukocyte Biology. 99, 6, p. 1141-1151 11 p.

Research output: Contribution to journalArticle

Macrophages
Cytokines
Video Microscopy
Candida albicans
Phosphatidylinositol 3-Kinases
12 Citations (Scopus)
7 Downloads (Pure)

Methionine restriction improves renal insulin signalling in aged kidneys

Grant, L., Lees, E. K., Forney, L. A., Mody, N., Gettys, T., Brown, P. A. J., Wilson, H. M. & Delibegovic, M., Jul 2016, In : Mechanisms of Ageing and Development. 157, p. 35-43 8 p.

Research output: Contribution to journalArticle

Open Access
File
Methionine
Insulin
Kidney
Gene Expression
Insulin Resistance
18 Citations (Scopus)
6 Downloads (Pure)

SOCS3 is a modulator of human macrophage phagocytosis

Gordon, P., Okai, B., Hoare, J. I., Erwig, L. P. & Wilson, H. M., Oct 2016, In : Journal of Leukocyte Biology. 100, 4, p. 771-780 10 p.

Research output: Contribution to journalArticle

Open Access
File
Phagocytosis
Macrophages
Phosphatidylinositol 3-Kinases
Suppressor of Cytokine Signaling Proteins
Video Microscopy
1 Citation (Scopus)
7 Downloads (Pure)

Sphingosylphosphorylcholine inhibits macrophage adhesion to vascular smooth muscle cells

Wirrig, C., McKean, J. S., Wilson, H. M. & Nixon, G. F., 1 Sep 2016, In : Biochemical Pharmacology. 115, p. 43-50 8 p.

Research output: Contribution to journalArticle

Open Access
File
Macrophages
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
Adhesion
2015
31 Citations (Scopus)
3 Downloads (Pure)

The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses

Arnold, C. E., Gordon, P., Barker, R. N. & Wilson, H. M., Jan 2015, In : Immunobiology. 220, 1, p. 10-19 10 p.

Research output: Contribution to journalArticle

Open Access
File
Macrophages
Efficiency
Antigens
Aptitude
Adaptive Immunity
2014
58 Citations (Scopus)
5 Downloads (Pure)

A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo

Arnold, C. E., Whyte, C. S., Gordon, P., Barker, R. N., Rees, A. J. & Wilson, H. M., Jan 2014, In : Immunology. 141, 1, p. 96-110 15 p.

Research output: Contribution to journalArticle

Open Access
File
Macrophage Activation
Cytokines
Macrophages
In Vitro Techniques
Interleukin-6
5 Citations (Scopus)

Comparison of fluorodeoxyglucose uptake in symptomatic carotid artery and stable femoral artery plaques

Shaikh, S., Welch, A., Ramalingam, S. L., Murray, A., Wilson, H. M., McKiddie, F. & Brittenden, J., Mar 2014, In : British Journal of Surgery. 101, 3, p. 363-370 8 p.

Research output: Contribution to journalArticle

Femoral Artery
Carotid Arteries
Macrophages
Thigh
Carotid Stenosis
9 Citations (Scopus)

Electric fields: a novel non-chemical regulator of human macrophage function

Hoare, J. I., Barker, R. N., Mccaig, C. C., Rajnicek, A. & Wilson, H. M., Dec 2014, In : Immunology. 143, Suppl 2, p. 96-96 1 p., 291.

Research output: Contribution to journalAbstract

38 Citations (Scopus)
26 Downloads (Pure)

Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dependent Mechanism

Grant, L., Shearer, K. D., Czopek, A., Lees, E. K., Owen, C., Agouni, A., Workman, J., Martin-Granados, C., Forrester, J. V., Wilson, H. M., Mody, N. & Delibegovic, M., Feb 2014, In : Diabetes. 63, 2, p. 456-470 15 p.

Research output: Contribution to journalArticle

Open Access
File
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Endotoxemia
Hyperinsulinism
High Fat Diet
Myeloid Cells
3 Citations (Scopus)

SOCS3: a novel regulator of phagocytosis in m1 macrophages

Gordon, P., Graham, A., Erwig, L. P. & Wilson, H. M., Dec 2014, In : Immunology. 143, Suppl 2, p. 101-101 1 p., 430.

Research output: Contribution to journalAbstract

50 Citations (Scopus)
4 Downloads (Pure)

SOCS Proteins in Macrophage Polarization and Function

Wilson, H. M., 28 Jul 2014, In : Frontiers in Immunology. 5, 357.

Research output: Contribution to journalArticle

Open Access
File
Suppressor of Cytokine Signaling Proteins
Macrophages
Innate Immunity
Regeneration
Homeostasis
2013

Cytokines

Wilson, H. M. & Barker, R. N., 15 Feb 2013, els. John Wiley & Sons

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytokines
Cytokine Receptors
Hematopoiesis
Cell Communication
Embryonic Development
18 Citations (Scopus)

Predominance of activated, clonally expanded T helper type 17 cells within the CD4+ T cell population in psoriatic lesions

Lewis, B. J., Rajpara, S., Haggart, A. M., Wilson, H. M., Barker, R. N. & Ormerod, A. D., Jul 2013, In : Clinical and Experimental Immunology. 173, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

Th17 Cells
T-Lymphocytes
Regulatory T-Lymphocytes
Psoriasis
Population
2012
8 Citations (Scopus)

Glomerular Epithelial and Mesangial Cell Culture and Characterization

Wilson, H. M. & Stewart, K. N., 2012, Human cell Culture Protocols. Mitry, R. R. & Hughes, R. D. (eds.). 3 ed. London, UK: Humana Press, Vol. 806. p. 187-201 15 p. (Methods in Molecular Biology; vol. 806).

Research output: Chapter in Book/Report/Conference proceedingChapter

Glomerular Epithelial and Mesangial Cell Culture and Characterization

Wilson, H. M. & Stewart, K. N., 2012, In : Methods in Molecular Biology. 806, p. 187-201 15 p.

Research output: Contribution to journalArticle

Mesangial Cells
Cell Culture Techniques
Epithelial Cells
Kidney
Kidney Cortex
8 Citations (Scopus)
lycopene
lymphocyte proliferation
Lymphocytes
T-lymphocytes
interleukin-2
41 Citations (Scopus)
4 Downloads (Pure)

Macrophage subtypes in symptomatic carotid artery and femoral artery plaques

Shaik, S., Brittenden, J., Lahiri, R., Brown, P. A. J., Thies, F. & Wilson, H. M., 1 Nov 2012, In : European Journal of Vascular and Endovascular Surgery. 44, 5, p. 491-497 7 p.

Research output: Contribution to journalArticle

Open Access
File
Femoral Artery
Thigh
Carotid Arteries
Macrophages
T-Lymphocytes
42 Citations (Scopus)

Role of cysteine residues and disulfide bonds in the activity of a legume root nodule-specific, cysteine-rich peptide

Haag, A. F., Kerscher, B., Dall'Angelo, S., Sani, M., Longhi, R., Baloban, M., Wilson, H. M., Mergaert, P., Zanda, M. & Ferguson, G. P., 30 Mar 2012, In : The Journal of Biological Chemistry. 287, 14, p. 10791-10798 8 p.

Research output: Contribution to journalArticle

Fabaceae
Disulfides
Cysteine
Sinorhizobium meliloti
Peptides
2011
120 Citations (Scopus)

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

Whyte, C. S., Bishop, E. T., Rückerl, D., Gaspar-Pereira, S., Barker, R. N., Allen, J. E., Rees, A. J. & Wilson, H. M., Nov 2011, In : Journal of Leukocyte Biology. 90, 5, p. 845-854 10 p.

Research output: Contribution to journalArticle

Macrophage Activation
Macrophages
Cytokines
Arginase
Interleukin-4
2010
50 Citations (Scopus)

Macrophages heterogeneity in atherosclerosis: implications for therapy

Wilson, H. M., Aug 2010, In : Journal of Cellular and Molecular Medicine. 14, 8, p. 2055-2065 11 p.

Research output: Contribution to journalArticle

Atherosclerosis
Macrophages
Therapeutics
Monocytes
Cytokines
2008
98 Citations (Scopus)

Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo

Liu, Y., Stewart, K. N., Bishop, E., Marek, C. J., Kluth, D. C., Rees, A. J. & Wilson, H. M., 1 May 2008, In : The Journal of Immunology. 180, 9, p. 6270-6278 9 p.

Research output: Contribution to journalArticle

2007

Cytokines

Wilson, H. M. & Barker, R. N., 30 Mar 2007, Encyclopedia of Life Sciences. Chichester, United Kingdom: John Wiley & Sons, (Encyclopedia of Life Sciences).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cytokines
Cytokine Receptors
Hematopoiesis
Cell Communication
Embryonic Development

Pathogenesis of Renal Disease: Cellular Mechanisms

Erwig, L-P., Wilson, H. M. & Rees, A. J., 2007, The Kidney in Systemic Autoimmune Diseases. Mason, J. C. & Pusey, C. D. (eds.). Amsterdam, Netherlands: Elsevier Science , Vol. 7. p. 81-92 12 p. (Handbook of Systemic Autoimmune Diseases; vol. 7).

Research output: Chapter in Book/Report/Conference proceedingChapter

2005
2 Citations (Scopus)

Glomerular epithelial and mesangial cell culture and characterization

Wilson, H. M. & Stewart, K. N., 1 Jan 2005, In : Methods in Molecular Medicine. 107, 1, p. 269-282 14 p.

Research output: Contribution to journalArticle

Mesangial Cells
Cell Culture Techniques
Epithelial Cells
Culture Techniques
Cell Line
68 Citations (Scopus)

Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo.

Wilson, H. M., Chettibi, S., Jobin, C., Walbaum, D., Rees, A. J. & Kluth, D. C., 2005, In : American Journal of Pathology. 167, 1, p. 27-37 10 p.

Research output: Contribution to journalArticle

2004
68 Citations (Scopus)

Macrophages and the kidney

Wilson, H. M., Walbaum, D. & Rees, A. J., 2004, In : Current Opinion in Nephrology and Hypertension. 13, 3, p. 285-290 5 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Selective expression of TGF-beta2 and TGF-beta3 isoforms in early mesangioproliferative glomerulonephritis.

Minto, A. W., Wilson, H. M., Rees, A. J., Quigg, R. J. & Brown, P. A. J., 2004, In : Nephron Experimental Nephrology. 96, 4, p. 111-118 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta3
Transforming Growth Factor beta2
Glomerulonephritis
Protein Isoforms
Transforming Growth Factor beta1
2002
59 Citations (Scopus)

Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis.

Wilson, H. M., Stewart, K. N., Brown, P. A. J., Anegon, I., Chettibi, S., Rees, A. J. & Kluth, D. C., 2002, In : Molecular Therapy. 6, p. 710-717 8 p.

Research output: Contribution to journalArticle

2001
56 Citations (Scopus)

Plasminogen activator inhibitor-1 and haemostasis in obesity

Mutch, N. J., Wilson, H. M. & Booth, N. A., Aug 2001, In : Proceedings of the Nutrition Society. 60, 3, p. 341-347 7 p.

Research output: Contribution to journalArticle

2000

Prolonged elevation of glomerular total cellularity and cell density, but only late matrix accumulation, precede accelerated proteinuria in Thy1 glomerulonephritis

Brown, P. A., Minto, A. W., Wilson, H. M., Haites, N., Whiting, P. H., Macleod, A. M., Stewart, K. N. & Wilson, P. J., Mar 2000, In : The Journal of pathology. 190, 1 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Transforming growth factor-beta isoforms and glomerular injury in nephrotoxic nephritis

Wilson, H. M., Minto, A. W. M., Brown, P. A. J., Erwig, L. P. & Rees, A. J., 2000, In : Kidney International. 57, p. 2434-2444 11 p.

Research output: Contribution to journalArticle

1996

A model of progressive mesangio-proliferative glomerulonephritis.

Stewart, K. N., Brown, P. A. J., Hall, A., Whiting, P. H., McKay, N. G., Wilson, H. M., Haites, N. E., Simpson, J. G., MacLeod, A. M. & Turner, A. N., Sep 1996, In : Journal of the American Society of Nephrology. 7, 9, 1 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704

Price, J. T., Wilson, H. M. & Haites, N. E., Oct 1996, In : European Journal of Cancer. 32, 11, p. 1977-1982 6 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Carcinoma
Kidney
Cell Line
Matrix Metalloproteinases
1995
6 Citations (Scopus)
1994
15 Citations (Scopus)

Urokinase-plasminogen activator is synthesized in vitro by human glomerular epithelial cells but not by mesangial cells

Brown, P. A. J., Wilson, H. M., Reid, F. J., Booth, N. A., Simpson, J. G., Morrison, L., Power, D. A. & Haites, N. E., Jan 1994, In : Kidney International. 45, 1, p. 43-47 5 p.

Research output: Contribution to journalArticle

Open Access
Mesangial Cells
Plasminogen Activators
Urokinase-Type Plasminogen Activator
Epithelial Cells
Fibrinolysin
1993
72 Citations (Scopus)

Alterations in the concentration of an apolipoprotein E-containing subfraction of plasma high density lipoprotein in coronary heart disease

Wilson, H. M., Patel, J. C., Russell, D. & Skinner, E. R., 15 Nov 1993, In : CLINICA CHIMICA ACTA. 220, 2, p. 175-187 13 p.

Research output: Contribution to journalArticle

Apolipoproteins E
HDL Lipoproteins
Coronary Disease
Plasmas
Cholesterol
31 Citations (Scopus)

Effect of transforming growth factor-beta 1 on plasminogen activators and plasminogen activator inhibitor-1 in renal glomerular cells.

Wilson, H. M., Reid, F. J., Brown, P. A., Power, D. A., Haites, N. E. & Booth, N. A., Nov 1993, In : Experimental Nephrology. 1, 6, p. 343-350 8 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Plasminogen Activator Inhibitor 1
Transforming Growth Factor beta
Mesangial Cells
Kidney
67 Citations (Scopus)

Induction of nitric oxide synthase in human mesangial cells

Nicolson, A. G., Haites, N. E., McKay, N. G., Wilson, H. M., MacLeod, A. M. & Benjamin, N., 30 Jun 1993, In : Biochemical and Biophysical Research Communications. 193, 3, p. 1269-74 6 p.

Research output: Contribution to journalArticle

Mesangial Cells
Nitric Oxide Synthase
omega-N-Methylarginine
Nitric Oxide
Rats
1992
20 Citations (Scopus)

The isolation and characterization of high-density-lipoprotein subfractions containing apolipoprotein E from human plasma

Wilson, H. M., Griffin, B. A., Watt, C. & Skinner, E. R., 1 Jun 1992, In : Biochemical Journal. 284, 2, p. 477-481 5 p.

Research output: Contribution to journalArticle

Plasma (human)
Apolipoproteins E
HDL Lipoproteins
Buffers
Fatty Acids
1990
8 Citations (Scopus)

High-density lipoprotein subfractions and cardiovascular disease

Skinner, E. R. & Wilson, H. M., 1 Dec 1990, In : Biochemical Society Transactions. 18, 6, p. 1074-1076 3 p.

Research output: Contribution to journalArticle