• 1974 Citations
19992019
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  • 5 Similar Profiles
Androgen Receptors Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Androgens Medicine & Life Sciences
Ligands Medicine & Life Sciences
Steroid Receptors Medicine & Life Sciences
Hormones Medicine & Life Sciences
Castration Medicine & Life Sciences

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Research Output 1999 2019

A New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Hwang, D-J., He, Y., Ponnusamy, S., Mohler, M. L., Thiyagarajan, T., McEwan, I. J., Narayanan, R. & Miller, D. D., 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 491-511 20 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgen Receptor Antagonists
Castration
Cyclization
1 Citation (Scopus)
5 Downloads (Pure)

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., D'Santos, C., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., Mills, I. G., Carroll, J. S. & 5 othersTilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., 2019, In : Oncogene. 38, p. 1136-1150 15 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
PDZ-binding kinase
Systems Biology
Proteome

Androgens and androgen receptor: Above and beyond

Gibson, D. A., Saunders, P. T. K. & McEwan, I. J., 15 Apr 2018, In : Molecular and Cellular Endocrinology. 465, p. 1-3 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
4 Downloads (Pure)

Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators

De Mol, E., Szulc, E., Di Sanza, C., Martínez-Cristóbal, P., Bertoncini, C. W., Fenwick, R. B., Frigolé-Vivas, M., Masín, M., Hunter, I., Buzón, V., Brun-Heath, I., García, J., De Fabritiis, G., Estébanez-Perpiñá, E., McEwan, I. J., Nebreda, Á. R. & Salvatella, X., 2 Jan 2018, In : Structure. 26, 1, p. 145-152 8 p.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Transcriptional Activation
Prostatic Neoplasms
Castration
Proteins
6 Citations (Scopus)
6 Downloads (Pure)

Tissue control of androgen action: The ups and downs of androgen receptor expression

Hunter, I., Hay, C. W., Esswein, B., Watt, K. & McEwan, I. J., 15 Apr 2018, In : Molecular and Cellular Endocrinology. 465, p. 27-35 9 p.

Research output: Contribution to journalReview article

Open Access
File
Androgen Receptors
Androgens
Genes
Tissue
Testosterone