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Research Output

2020

Ovine prenatal growth-restriction and sex influence fetal adipose tissue phenotype and impact postnatal lipid metabolism and adiposity in vivo from birth until adulthood

Wallace, J. M., Milne, J. S., Aitken, B. W., Aitken, R. P. & Adam, C. L., 14 Feb 2020, In : PloS ONE. 15, 2, e0228732.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)
Open Access
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7 Citations (Scopus)
2018

Ovine prenatal growth restriction impacts glucose metabolism and body composition throughout life in both sexes

Wallace, J. M., Milne, J. S., Aitken, R. P., Horgan, G. W. & Adam, C. L., 1 Aug 2018, In : Reproduction. 156, 2, p. 103-119 17 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
5 Downloads (Pure)
2017

Impact of donor and recipient adiposity on placental and fetal growth in adolescent sheep

Wallace, J. M., Milne, J. S., Adam, C. L. & Aitken, R. P., Apr 2017, In : Reproduction. 153, 4, p. 381-394 14 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
9 Citations (Scopus)
6 Downloads (Pure)
2016

Epigenetics and developmental programming of welfare and production traits in farm animals

Sinclair, K. D., Rutherford, K. M. D., Wallace, J. M., Brameld, J. M., Stoger, R., Alberio, R., Sweetman, D., Gardner, D. S., Perry, V. E. A., Adam, C. L., Ashworth, C. J., Robinson, J. E. & Dwyer, C. M., 2016, In : Reproduction, Fertility and Development. 28, 10, p. 1443-1478 36 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
5 Downloads (Pure)

Inter-Pregnancy Weight Change and the Risk of Recurrent Pregnancy Complications

Wallace, J. M., Bhattacharya, S., Campbell, D. M. & Horgan, G. W., 4 May 2016, In : PloS ONE. 11, 5, p. 1-14 14 p., 0154812.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
8 Downloads (Pure)

Peri- and postnatal effects of prenatal adenoviral VEGF gene therapy in growth-restricted sheep

Carr, D. J., Wallace, J. M., Aitken, R. P., Milne, J. S., Martin, J. F., Zachary, I. C., Peebles, D. M. & David, A. L., 1 Jun 2016, In : Biology of Reproduction. 94, 6, 142.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
1 Downloads (Pure)

Placental vascularity and markers of angiogenesis in relation to prenatal growth status in overnourished adolescent ewes

Carr, D. J., David, A. L., Aitken, R. P., Milne, J. S., Borowicz, P. P., Wallace, J. M. & Redmer, D. A., Oct 2016, In : Placenta. 46, p. 79-86 8 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
5 Downloads (Pure)

Young maternal age, body composition and gestational intake impact pregnancy outcome: translational perspectives

Wallace, J. M., 2016, Parental Obesity: Intergenerational programming and consequences. Green, L. & Hester, R. (eds.). 1 ed. New York: Springer-Verlag, p. 57-80 24 p. (Physiology in Health and Disease).

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics; biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth and fetal growth restriction

Barbaux, S., Erwich, J. J. H. M., Favaron, P. O., Gil, S., Gallot, D., Golos, T. G., Gonzalez-Bulnes, A., Guibourdenche, J., Heazell, A. E. P., Jansson, T., Laprévote, O., Lewis, R. M., Miller, R. K., Monk, D., Novakovic, B., Oudejans, C., Parast, M., Peugnet, P., Pfarrer, C., Pinar, H. & 13 others, Roberts, C. T., Robinson, W., Saffery, R., Salomon, C., Sexton, A., Staff, A. C., Suter, M., Tarrade, A., Wallace, J., Vaillancourt, C., Vaiman, D., Worton, S. A. & Lash, G. E., 1 Apr 2015, In : Placenta. 36, S1, p. S5-S10 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inter-pregnancy weight change and pregnancy hypertension

Campbell, D. M., Bhattacharya, S., Horgan, G. & Wallace, J., Jan 2015, In : Pregnancy Hypertension. 5, 1, p. 67 1 p., 126-POS.

Research output: Contribution to journalAbstract

Orexigenic Gene Expression in Late Gestation Ovine Foetal Hypothalamus is Sensitive to Maternal Undernutrition and Realimentation

Adam, C. L., Williams, P. A., Milne, J. S., Aitken, R. P. & Wallace, J. M., Oct 2015, In : Journal of Neuroendocrinology. 27, 10, p. 765-771 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)

Undernutrition and stage of gestation influence fetal adipose tissue gene expression

Wallace, J. M., Milne, J. S., Aitken, R. P., Redmer, D. A., Reynolds, L. P., Luther, J. S., Horgan, G. W. & Adam, C. L., 1 Jun 2015, In : Journal of Molecular Endocrinology. 54, 3, p. 263-275 13 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
5 Downloads (Pure)

VEGF Gene Transfer to the Utero-Placental Circulation of Pregnant Sheep to Enhance Fetal Growth

Carr, D. J., Mehta, V., Wallace, J. & David, A. L., 2015, VEGF Signalling: Methods and Protocols, Methods in Molecular Biology. Fiedler, L. (ed.). First ed. New York: Springer , p. 197-204 8 p. (Methods in Molecular Biology; vol. 1332).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)
2014
9 Citations (Scopus)

Influence of birth weight and gender on lipid status and adipose tissue gene expression in lambs

Wallace, J. M., Milne, J. S., Aitken, R. P. & Adam, C. L., 1 Aug 2014, In : Journal of Molecular Endocrinology. 53, 1, p. 131-144 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
Open Access
File
29 Citations (Scopus)
9 Downloads (Pure)
2013

A case of successful pregnancy in a ewe with Uterine Didelphys

Carr, DJ., Aitken, RP., Milne, JS., David, AL. & Wallace, JM., Oct 2013, In : Reproduction in Domestic Animals. 48, 5, p. e78-e80 3 p.

Research output: Contribution to journalArticle

Gestational age, gender and parity specific charts for placental weight for singleton deliveries in Aberdeen, UK

Wallace, J., Bhattacharya, S. & Horgan, G., Mar 2013, In : Placenta. 34, 3, p. 269-274 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Impact of birth weight and gender on early postnatal hypothalamic energy balance regulatory gene expression in the young lamb

Adam, C. L., Bake, T., Findlay, P. A., Milne, J. S., Aitken, R. P. & Wallace, J. M., Nov 2013, In : International Journal of Developmental Neuroscience. 31, 7, p. 608-615 8 p.

Research output: Contribution to journalArticle

File
13 Citations (Scopus)
1 Downloads (Pure)
2012

Adverse metabolic phenotype in low-birth-weight lambs and its modification by postnatal nutrition

Wallace, J. M., Milne, J. S., Adam, C. L. & Aitken, R. P., 28 Feb 2012, In : British Journal of Nutrition. 107, 4, p. 510-522 13 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Decreasing maternal nutrient intake during the final third of pregnancy in previously overnourished adolescent sheep: effects on maternal nutrient partitioning and feto-placental development

Redmer, D. A., Milne, J. S., Aitken, R. P., Johnson, M. L., Borowicz, P. P., Reynolds, L. P., Caton, J. S. & Wallace, J. M., Feb 2012, In : Placenta. 33, 2, p. 114-121 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Fetoplacental biometry and umbilical artery Doppler velocimetry in the overnourished adolescent model of fetal growth restriction

Carr, D. J., Aitken, R., Milne, J., David, A. L. & Wallace, J., Aug 2012, In : American Journal of Obstetrics and Gynecology. 207, 2, p. 1410.e6-141.e15 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

In vivo changes in central and peripheral insulin sensitivity in a large animal model of obesity

Adam, C. L., Findlay, P. A., Aitken, R. P., Milne, J. S. & Wallace, J. M., Jul 2012, In : Endocrinology. 153, 7, p. 3147-3157 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Monitoring for potential adverse effects of prenatal gene therapy: use of large animal models with relevance to human application

Mehta, V., Abi-Nader, K., Carr, D., Wallace, J., Coutelle, C., Waddington, S., Peebles, D. & David, A., 2012, In : Methods in Molecular Biology. 891, p. 291-328 38 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
83 Citations (Scopus)
2011

Central and peripheral insulin resistance in a large animal model of obesity

Adam, C. L., Findlay, P., Aitken, R., Milne, J. & Wallace, J., 2011, In : Proceedings of the Nutrition Society. 70, OCE6, 1 p., E381.

Research output: Contribution to journalAbstract

Open Access
File
6 Downloads (Pure)
10 Citations (Scopus)

Growth, body composition and metabolism at neonatal and adolescent life stages in low birth weight offspring

Wallace, J., Aitken, R., Milne, J., Bake, T. & Adam, C. L., Apr 2011, In : Proceedings of the Nutrition Society. 70, OCE1, E7.

Research output: Contribution to journalAbstract

Open Access
File
4 Downloads (Pure)
5 Downloads (Pure)

Postnatal hypothalamic-pituitary-adrenal function in sheep is influenced by age and sex, but not by prenatal growth restriction

Wallace, J., Milne, J., Green, L. R. & Aitken, R., Jan 2011, In : Reproduction, Fertility and Development. 23, 2, p. 275-284 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Prenatal Ad.VEGF gene therapy - a promising new treatment for fetal growth restriction

Carr, D. J., Aitken, R. P., Milne, J., Peebles, D. M., Martin, J. F., Zachary, I. C., Wallace, J. & David, A. L., Oct 2011, In : Human Gene Therapy. 22, 10, p. A128 1 p.

Research output: Contribution to journalBook/Film/Article review

Ultrasonographic assessment of growth and estimation of birthweight in late gestation fetal sheep

Carr, D. J., Aitken, R. P., Milne, J. S., David, A. L. & Wallace, J. M., Oct 2011, In : Ultrasound in Medicine & Biology. 37, 10, p. 1588-1595 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2010
37 Citations (Scopus)
2 Citations (Scopus)
2009

Adiposity and Glycemia Can Influence Central Energy Balance Regulatory Pathways in Late Gestation Growth-Restricted Ovine Fetuses

Adam, C. L., Bake, T., Findlay, P. A., Milne, J., Aitken, R. & Wallace, J., Mar 2009, In : Reproductive Sciences. 16, 3, p. 321A 1 p.

Research output: Contribution to journalAbstract

Effects of maternal nutrition and stage of gestation on body weight, visceral organ mass, and indices of jejunal cellularity, proliferation, and vascularity in pregnant ewe lambs

Caton, J., Reed, J. J., Aitken, R., Milne, J., Borowicz, P. P., Reynolds, L. P., Redmer, D. A. & Wallace, J., Jan 2009, In : Journal of Animal Science. 87, 1, p. 222-235 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Fetoplacental growth and vascular development in overnourished adolescent sheep at day 50, 90 and 130 of gestation

Redmer, D. A., Luther, J. S., Milne, J., Aitken, R., Johnson, M. L., Borowicz, P. P., Borowicz, M. A., Reynolds, L. P. & Wallace, J., Apr 2009, In : Reproduction. 137, 4, p. 749-757 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2008

Effect of weight and adiposity at conception and gestational dietary intake on pregnancy outcome in young adolescent sheep

Aitken, R., Milne, J. & Wallace, J., 2008, Proceedings of the Physiological Soceity. Vol. 11. p. PC36 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

18 Citations (Scopus)

Influence of maternal nutrition on placental mRNA expression of angiogenic factors (AF) and their receptors (AFR) in adolescent sheep at days 50 and 75 of pregnancy

Redmer, D., Aitken, R., Milne, J., Johnson, M., Carlson, D., Reynolds, L. & Wallace, J., May 2008, In : Biology of Reproduction. Supp.1, p. 217-217 1 p.

Research output: Contribution to journalArticle

Nutrition, placental growth and pregnancy outcome

Wallace, J., 2008, Proceedings of the Physiological Society. p. SA17 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Putative role for oestrogen as the missing link between nutrition and feto-placental growth restriction in overnourished adolescent sheep

Wallace, J., Milne, J., Aitken, R., Redmer, D. A. & Reynolds, L. P., 2008, Proceedings of the Physiological Society. Vol. 11. p. PC37 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Serial measurement of uterine blood flow from mid to late gestation in growth restricted pregnancies induced by overnourishing adolescent sheep dams

Wallace, J. M., Milne, J. S., Matsuzaki, M. & Aitken, R. P., Aug 2008, In : Placenta. 29, 8, p. 718-724 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2007

An immunochemical study of the localisation and developmental expression of ghrelin and its functional receptor in the ovine placenta

Harrison, JL., Adam, C., Brown, YA., Wallace, J., Aitken, R., Lea, R. & Miller, DW., 2007, In : Reproductive Biology and Endocrinology. 5, Art 25

Research output: Contribution to journalArticle

Maternal and Fetal Growth, Body Composition, Endocrinology, and Metabolic Status in Undernourished Adolescent Sheep

Luther, J. S., Aitken, R., Milne, J., Matsuzaki, M., Reynolds, L., Redmer, D. A. & Wallace, J., 1 Aug 2007, In : Biology of Reproduction. 77, 2, p. 343-350 8 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Placental Growth, Angiogenic Gene Expression, and Vascular Development in Undernourished Adolescent Sheep

Luther, J. S., Milne, J., Aitken, R. P., Matsuzaki, M., Reynolds, L., Redmer, D. A. & Wallace, J., 2007, In : Biology of Reproduction. 77, 2, p. 351-357 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep

Wallace, J., Milne, J., Aitken, R. & Hay, W., Nov 2007, In : American Journal of Physiology: Endocrinology and Metabolism. 293, 5, p. E1233-E1241 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)