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    • AB25 2ZD

    • 161 Citations
    19992018
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    Fingerprint Dive into the research topics where Janet Elizabeth Rickard is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 16 Similar Profiles
    Tauopathies Medicine & Life Sciences
    Alzheimer Disease Medicine & Life Sciences
    tau Proteins Medicine & Life Sciences
    Transgenic Mice Medicine & Life Sciences
    Synucleins Medicine & Life Sciences
    Salts Chemical Compounds
    Parkinson Disease Medicine & Life Sciences
    Brain Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 1999 2018

    6 Citations (Scopus)
    16 Downloads (Pure)

    Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

    Frahm, S., Melis, V., Horsley, D., Rickard, J. E., Riedel, G., Fadda, P., Scherma, M., Harrington, C. R., Wischik, C. M., Theuring, F. & Schwab, K., 26 Feb 2018, In : Behavioural Brain Research. 339, p. 153-168 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    alpha-Synuclein
    Transgenic Mice
    Parkinson Disease
    Lewy Body Disease
    Amphetamine
    1 Citation (Scopus)
    11 Downloads (Pure)
    Open Access
    File
    Synucleins
    Transgenic Mice
    Proteins
    Parkinson Disease
    Endopeptidase K
    1 Citation (Scopus)
    7 Downloads (Pure)

    Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)

    Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In : Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Cysteine
    Alzheimer Disease
    Tauopathies
    tau Proteins
    Neurofibrillary Tangles
    10 Citations (Scopus)
    13 Downloads (Pure)

    Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking

    Al-Hilaly, Y. K., Pollack, S. J., Vadukul, D., Citossi, F., Rickard, J. E., Simpson, M., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 24 Nov 2017, In : Journal of Molecular Biology. 429, 23, p. 3650-3665 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    tau Proteins
    Disulfides
    Alzheimer Disease
    Amyloidogenic Proteins
    Neurofibrillary Tangles
    2 Citations (Scopus)

    Assays for the Screening and Characterization of Tau Aggregation Inhibitors

    Rickard, J. E., Horsley, D., Wischik, C. M. & Harrington, C. R., 15 Dec 2016, Tau Protein: Methods and Protocols. Smet-Nocca, C. (ed.). Springer , Vol. 1523. p. 129-140 12 p. (Methods in Molecular Biology; vol. 1523).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    tau Proteins
    Tauopathies
    Immunoassay
    Recombinant Proteins
    Alzheimer Disease

    Impacts

    Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease

    Claude Michel Wischik (Participant), Charles Robert Harrington (Participant), John Mervyn David Storey (Participant), Janet Elizabeth Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven John Kemp (Participant), James Peter Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant), C Marshall (Participant)

    Impact: Quality of life Impacts, Economic Impacts