• 173 Citations
19992018
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Fingerprint Dive into the research topics where Janet Rickard is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 16 Similar Profiles
Tauopathies Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
tau Proteins Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Synucleins Medicine & Life Sciences
Salts Chemical Compounds
Parkinson Disease Medicine & Life Sciences
Brain Medicine & Life Sciences

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Research Output 1999 2018

7 Citations (Scopus)
19 Downloads (Pure)

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

Frahm, S., Melis, V., Horsley, D., Rickard, J. E., Riedel, G., Fadda, P., Scherma, M., Harrington, C. R., Wischik, C. M., Theuring, F. & Schwab, K., 26 Feb 2018, In : Behavioural Brain Research. 339, p. 153-168 16 p.

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Transgenic Mice
Parkinson Disease
Lewy Body Disease
Amphetamine
3 Citations (Scopus)
11 Downloads (Pure)
Open Access
File
Synucleins
Transgenic Mice
Proteins
Parkinson Disease
Endopeptidase K
3 Citations (Scopus)
8 Downloads (Pure)

Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)

Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In : Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.

Research output: Contribution to journalArticle

Open Access
File
Cysteine
Alzheimer Disease
Tauopathies
tau Proteins
Neurofibrillary Tangles
11 Citations (Scopus)
14 Downloads (Pure)

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking

Al-Hilaly, Y. K., Pollack, S. J., Vadukul, D., Citossi, F., Rickard, J. E., Simpson, M., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 24 Nov 2017, In : Journal of Molecular Biology. 429, 23, p. 3650-3665 16 p.

Research output: Contribution to journalArticle

Open Access
File
tau Proteins
Disulfides
Alzheimer Disease
Amyloidogenic Proteins
Neurofibrillary Tangles
2 Citations (Scopus)

Assays for the Screening and Characterization of Tau Aggregation Inhibitors

Rickard, J. E., Horsley, D., Wischik, C. M. & Harrington, C. R., 15 Dec 2016, Tau Protein: Methods and Protocols. Smet-Nocca, C. (ed.). Springer , Vol. 1523. p. 129-140 12 p. (Methods in Molecular Biology; vol. 1523).

Research output: Chapter in Book/Report/Conference proceedingChapter

tau Proteins
Tauopathies
Immunoassay
Recombinant Proteins
Alzheimer Disease

Impacts

Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease

Claude Wischik (Participant), Charles Harrington (Participant), John Storey (Participant), Janet Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven Kemp (Participant), James Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant), C Marshall (Participant)

Impact: Quality of life Impacts, Economic Impacts