Photo of John Hamilton Beattie
    • AB25 2ZD

    • 3642 Citations
    1978 …2019
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    Research Output 1978 2019

    2019

    Acute dietary zinc deficiency in rats exacerbates myocardial ischaemia/reperfusion injury through depletion of glutathione

    Skene, K., Walsh, S. K., Okafor, O., Godsman, N., Barrows, C., Meier, P., Gordon, M. J., Beattie, J. H. & Wainwright, C. L., 14 May 2019, In : British Journal of Nutrition. 121, 9, p. 961-973 13 p.

    Research output: Contribution to journalArticle

    Myocardial Reperfusion Injury
    Reperfusion Injury
    Myocardial Ischemia
    Glutathione
    Zinc
    2017
    13 Citations (Scopus)

    Zinc transporters and dysregulated channels in cancers

    Pan, Z., Choi, S., Ouadid-Ahidouch, H., Yang, J-M., Beattie, J. H. & Korichneva, I., 1 Jan 2017, In : Frontiers in Bioscience. 22, p. 623-643 21 p.

    Research output: Contribution to journalArticle

    Open Access
    Zinc
    Neoplasms
    Ion Channels
    Carcinogenesis
    Homeostasis
    2015
    45 Citations (Scopus)

    Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, M. J., Beattie, J. H. & Galley, H. F., Jun 2015, In : British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalArticle

    Open Access
    Selenium
    Zinc
    Sepsis
    Inflammation
    Oxidative Stress
    5 Citations (Scopus)

    Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice

    Duthie, S. J., Beattie, J. H., Gordon, M-J., Pirie, L. P., Nicol, F., Reid, M. D., Duncan, G. J., Cantlay, L., Horgan, G. & McNeil, C. J., Jan 2015, In : Genes & Nutrition. 10, 1, 11 p., 446.

    Research output: Contribution to journalArticle

    Vitamin B Deficiency
    Apolipoproteins E
    Vitamin B Complex
    Vascular Smooth Muscle
    Smooth Muscle Myocytes
    2014
    9 Citations (Scopus)
    Trace Elements
    Laser Therapy
    Mass Spectrometry
    Synchrotrons
    Spatial Analysis
    2013
    18 Citations (Scopus)

    Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling

    Alcantara, E. H., Shin, M. Y., Feldmann, J., Nixon, G. F., Beattie, J. H. & Kwun, I. S., 1 May 2013, In : Atherosclerosis. 228, 1, p. 46-52 7 p.

    Research output: Contribution to journalArticle

    Vascular Smooth Muscle
    Smooth Muscle Myocytes
    Zinc
    Down-Regulation
    Cell Proliferation
    13 Citations (Scopus)

    Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries

    Allen-Redpath, K., Ou, O., Beattie, J. H., Kwun, I-S., Feldmann, J. & Nixon, G. F., 1 Aug 2013, In : Cardiovascular Research. 99, 3, p. 525–534 10 p.

    Research output: Contribution to journalArticle

    Vascular Smooth Muscle
    Smooth Muscle Myocytes
    Zinc
    Arteries
    Apoptosis
    6 Citations (Scopus)

    Plasma zinc's alter ego is a low-molecular-weight humoral factor

    Ou, O., Allen-Redpath, K., Urgast, D., Gordon, M-J., Campbell, G., Feldmann, J., Nixon, G. F., Mayer, C-D., Kwun, I-S. & Beattie, J. H., Sep 2013, In : The FASEB Journal. 27, 9, p. 3672-3682 11 p.

    Research output: Contribution to journalArticle

    Ego
    Zinc
    Molecular Weight
    Molecular weight
    Plasmas
    2012
    19 Citations (Scopus)
    14 Citations (Scopus)

    Multi-elemental bio-imaging of rat tissue from a study investigating the bioavailability of bismuth from shotgun pellets

    Urgast, D. S., Ellingsen, D. G., Berlinger, B., Eilertsen, E., Friisk, G., Skaug, V., Thomassen, Y., Beattie, J. H., Kwun, I-S. & Feldmann, J., Jul 2012, In : Analytical and Bioanalytical Chemistry. 404, 1, p. 89-99 11 p.

    Research output: Contribution to journalArticle

    10 Citations (Scopus)
    vitamin B deficiency
    Vitamin B Deficiency
    Adventitia
    Apolipoproteins E
    aorta
    16 Citations (Scopus)

    Suboptimal dietary zinc intake promotes vascular inflammation and atherogenesis in a mouse model of atherosclerosis

    Beattie, J. H., Gordon, M-J., Duthie, S. J., McNeil, C. J., Horgan, G. W., Nixon, G. F., Feldmann, J. & Kwun, I-S., Jul 2012, In : Molecular Nutrition & Food Research. 56, 7, p. 1097-1105 9 p.

    Research output: Contribution to journalArticle

    atherogenesis
    atherosclerosis
    blood vessels
    Blood Vessels
    Zinc
    23 Citations (Scopus)

    Zinc isotope ratio imaging of rat brain thin sections from stable isotope tracer studies by LA-MC-ICP-MS

    Urgast, D. S., Hill, S., Kwun, I-S., Beattie, J. H., Goenaga-Infante, H. & Feldmann, J., 1 Oct 2012, In : Metallomics. 4, 10, p. 1057-1063 7 p.

    Research output: Contribution to journalArticle

    2011
    17 Citations (Scopus)
    Folic Acid Deficiency
    Hyperhomocysteinemia
    Apolipoproteins E
    DNA Methylation
    Folic Acid
    20 Citations (Scopus)

    Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis

    Beattie, J. H., Nicol, F., Gordon, M. J., Reid, M. D., Cantlay, L., Horgan, G. W., Kwun, I-S., Ahn, J-Y. & Ha, T-Y., Sep 2011, In : Molecular Nutrition & Food Research. 55 , Supplement 2, p. S203-213 10 p.

    Research output: Contribution to journalArticle

    Ginger
    ginger
    Phytochemicals
    High Fat Diet
    high fat diet
    45 Citations (Scopus)

    Metabolomics and human nutrition

    Primrose, S., Draper, J., Elsom, R., Kirkpatrick, V., Mathers, J. C., Seal, C., Beckmann, M., Haldar, S., Beattie, J. H., Lodge, J. K., Jenab, M., Keun, H. & Scalbert, A., 28 Apr 2011, In : British Journal of Nutrition. 105, 8, p. 1277-1283 7 p.

    Research output: Contribution to journalArticle

    Metabolomics
    Biomarkers
    Research
    Public Health
    Eating
    20 Citations (Scopus)

    Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts

    Alcantara, E. H., Lomeda, R-A. R., Feldmann, J., Nixon, G. F., Beattie, J. H. & Kwun, I-S., Oct 2011, In : Molecular Nutrition & Food Research. 55, 10, p. 1552-1560 9 p.

    Research output: Contribution to journalArticle

    2010
    96 Citations (Scopus)

    Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation

    Kwun, I-S., Cho, Y-E., Lomeda, R-A. R., Shin, H-I., Choi, J-Y., Kang, Y-H. & Beattie, J. H., Mar 2010, In : Bone. 46, 3, p. 732-741 10 p.

    Research output: Contribution to journalArticle

    2009
    47 Citations (Scopus)

    Preliminary evidence of immune function modulation by thyroid hormones in healthy men and women aged 55-70 years

    Hodkinson, C. F., Simpson, E. E. A., Beattie, J. H., O'Connor, J. M., Campbell, D. J., Strain, J. J. & Wallace, J. M. W., 1 Jul 2009, In : Journal of Endocrinology. 202, 1, p. 55-63 9 p.

    Research output: Contribution to journalArticle

    21 Citations (Scopus)

    Rapid Quantification of Aortic Lesions in ApoE(-/-) Mice

    Beattie, J. H., Duthie, S. J., Kwun, I-S., Ha, T-Y. & Gordon, M. J., Jun 2009, In : Journal of Vascular Research. 46, 4, p. 347-352 6 p.

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    The impact of rapid economic growth and globalization on zinc nutrition in South Korea

    Kwun, I-S., Do, M-S., Chung, H-R., Kim, Y. H. & Beattie, J. H., Aug 2009, In : Public Health Nutrition. 12, 8, p. 1234-1241 8 p.

    Research output: Contribution to journalArticle

    2008
    21 Citations (Scopus)

    Aorta protein networks in marginal and acute zinc deficiency

    Beattie, J. H., Gordon, M. J., Rucklidge, G. J., Reid, M. D., Duncan, G. J., Horgan, G. W., Cho, Y-E. & Kwun, I-S., May 2008, In : Proteomics. 8, 10, p. 2126-2135 10 p.

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Impact of overexpression of metallothionein-1 on cell cycle progression and zinc toxicity

    Smith, P. J., Wiltshire, M., Furon, E., Beattie, J. H. & Errington, R. J., Nov 2008, In : American Journal of Physiology: Cell Physiology. 295, 5, p. C1399-C1408 10 p.

    Research output: Contribution to journalArticle

    Zinc deficiency decreased cell viability both in endothelial EA.hy926 cells and mouse aortic culture ex vivo and its implication for anti-atherosclerosis

    Cho, Y-E., Choi, J-E., Alam, M. J., Lee, M-H., Sohn, H-Y., Beattie, J. H. & Kwun, I-S., Jun 2008, In : Nutrition Research and Practice. 2, 2, p. 74-79 6 p.

    Research output: Contribution to journalArticle

    atherosclerosis
    cell viability
    Zinc
    Cell Survival
    Atherosclerosis
    2007
    17 Citations (Scopus)

    Assessment of zinc and copper status in weaned piglets in relation to dietary zinc and copper supply

    Carlson, D., Beattie, J. H. & Poulsen, H. D., Feb 2007, In : Journal of Animal Physiology and Animal Nutrition. 91, 1-2, p. 19-28 10 p.

    Research output: Contribution to journalArticle

    Cellular Zn depletion by metal ion chelators (TPEN, DTPA and chelex resin) and its application to osteoblastic MC3T3-E1 cells

    Cho, Y-E., Lomeda, R-A. R., Ryu, S-H., Lee, J-H., Beattie, J. H. & Kwun, I-S., 2007, In : Nutrition Research and Practice. 1, 1, p. 29-35 7 p.

    Research output: Contribution to journalArticle

    Pentetic Acid
    Chelating Agents
    chelating agents
    metal ions
    resins

    Leptin signaling through the JAK2-STAT3 pathway under Zn deficiency in osteoblastic MC3T3-E1 cells

    Kwun, I-S., Lomeda, R-A. R., Cho, Y-E., Kim, H-J., Shin, H-I., Choi, B-H., Do, M-S. & Beattie, J. H., Apr 2007, In : The FASEB Journal. 21, Suppl., p. A1109 1 p.

    Research output: Contribution to journalAbstract

    20 Citations (Scopus)

    Marginal zinc deficiency in rats decreases leptin expression independently of food intake and corticotrophin-releasing hormone in relation to food intake

    Kwun, I-S., Cho, Y-E., Lomeda, R-A. R., Kwon, S-T., Kim, Y. & Beattie, J. H., Sep 2007, In : British Journal of Nutrition. 98, 3, p. 485-489 5 p.

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Mononuclear cell metallothionein mRNA levels in human subjects with poor zinc nutrition

    Kwon, C-S., Kountouri, A. M., Mayer, C., Gordon, M-J., Kwun, I-S. & Beattie, J. H., Feb 2007, In : British Journal of Nutrition. 97, 2, p. 247-254 8 p.

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    Stable isotope pilot study of exchangeable copper kinetics in human blood plasma

    Venelinov, T. I., Beattie, J. H., Dainty, J. R., Hollands, W. J., Fairweather-Tait, S. J. & Harvey, L. J., Jun 2007, In : Journal of Trace Elements in Medicine and Biology. 21, 2, p. 138-140 3 p.

    Research output: Contribution to journalArticle

    Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats

    Cho, Y-E., Lomeda, R-A. R., Ryu, S-H., Sohn, H-Y., Shin, H-I., Beattie, J. H. & Kwun, I-S., 2007, In : Nutrition Research and Practice. 1, 2, p. 113-119 7 p.

    Research output: Contribution to journalArticle

    Alkaline Phosphatase
    alkaline phosphatase
    Zinc
    zinc
    Minerals
    2006

    A proteomic analysis of aortic proteins in zinc and metallothionein deficiency

    Beattie, J. H., Gordon, M. J., Rucklidge, G. J., Reid, M. D. & Kwun, I. S., 2006, In : Proceedings of the Nutrition Society. 65, Supplement OCA-B, p. 86A-86A 1 p.

    Research output: Contribution to journalBook/Film/Article review

    A proteomic analysis of aortic proteins in zinc and metallothionein deficiency

    Beattie, J. H., Gordon, M. J., Rucklidge, G. J., Reid, M. D., Duncan, G. & Kwun, I-S., 7 Mar 2006, In : The FASEB Journal. 20, 5, p. A995-A995 1 p.

    Research output: Contribution to journalBook/Film/Article review

    4 Citations (Scopus)

    Hepatic responses to dietary stress in zinc- and metallothionein-deficient mice

    Beattie, J. H., Gordon, M. J., Reid, M. D., Rucklidge, G. J., Kwon, C-S. & Kwun, I-S., Oct 2006, In : Experimental Biology and Medicine. 231, 9, p. 1542-1547 6 p.

    Research output: Contribution to journalArticle

    18 Citations (Scopus)

    Properties of the copper(II)-histidine complex obtained after dialysis of human plasma with histidine

    Venelinov, T., Arpadjan, S., Karadjova, I. & Beattie, J. H., 1 Mar 2006, In : Acta Pharmaceutica. 56, 1, p. 105-112 8 p.

    Research output: Contribution to journalArticle

    Histidine
    Dialysis
    Cation Exchange Resins
    Ion Exchange Resins
    Dialysis Solutions

    Zn increased extracellular matrix mineralization, bone-related genes and runx2 expression in osteoblastic MC3T3-E1 cells

    Kwun, I-S., Cho, Y-E., Kim, H-J., Lomeda, R-A. R., Beattie, J. H., Kim, H-J. & Choi, J-Y., 6 Mar 2006, In : The FASEB Journal. 20, 4, p. A561-A561 1 p.

    Research output: Contribution to journalBook/Film/Article review

    2005
    9 Citations (Scopus)

    Basal metabolic rate and thyroid hormones of late-middle-aged and older human subjects: the ZENITH study

    Meunier, N., Beattie, J. H., Ciarapica, D., O'Connor, J. M., Andriollo-Sanchez, M., Taras, A., Coudray, C. & Polito, A., Nov 2005, In : European Journal of Clinical Nutrition. 59, Supplement 2, p. S53-S57 5 p.

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Copper absorption from foods labelled intrinsically and extrinsically with Cu-65 stable isotope

    Harvey, L. J., Dainty, J. R., Beattie, J. H., Majsak-Newman, G., Wharf, S. G. & Fairweather-Tait, S. J., Mar 2005, In : European Journal of Clinical Nutrition. 59, 3, p. 363-368 6 p.

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Lower antioxidant vitamins (A, C and E) and trace minerals (Zn, Cu, Mn, Fe and Se) status in patients with cerebrovascular disease

    Kwun, I. S., Park, K. H., Jang, H. S., Beattie, J. H. & Kwon, C-S., Aug 2005, In : Nutritional Neuroscience. 8, 4, p. 251-257 7 p.

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Use of mathematical modeling to study copper metabolism in humans

    Harvey, L. J., Dainty, J. R., Hollands, W. J., Bull, V. J., Beattie, J. H., Venelinov, T. I., Hoogewerff, J. A., Davies, I. M. & Fairweather-Tait, S. J., Apr 2005, In : The American Journal of Clinical Nutrition. 81, 4, p. 807-813 7 p.

    Research output: Contribution to journalArticle

    2004
    15 Citations (Scopus)

    Dialysis-Chelex method for determination of exchangeable copper in human plasma

    Venelinov, T. I., Davies, I. M. & Beattie, J. H., Jul 2004, In : Analytical and Bioanalytical Chemistry. 379, 5-6, p. 777-780 4 p.

    Research output: Contribution to journalArticle

    72 Citations (Scopus)

    Is zinc deficiency a risk factor for atherosclerosis?

    Beattie, J. H. & Kwun, I-S., Feb 2004, In : British Journal of Nutrition. 91, 2, p. 177-181 5 p.

    Research output: Contribution to journalArticle

    2003
    25 Citations (Scopus)

    Copper-homocysteine complexes and potential physiological actions

    Apostolova, M. D., Bontchev, P. R., Ivanova, B. B., Russell, W. R., Mehandjiev, D. R., Beattie, J. H. & Nachev, C. K., 1 Jul 2003, In : Journal of Inorganic Biochemistry. 95, 4, p. 321-333 13 p.

    Research output: Contribution to journalArticle

    Paxillin
    Endothelial cells
    Homocysteine
    Action Potentials
    Copper
    2002
    14 Citations (Scopus)

    Holmium as a faecal marker for copper absorption studies in adults

    Harvey, L. J., Majsak-Newman, G., Dainty, J. R., Wharf, S. G., Reid, M. D., Beattie, J. H. & Fairweather-Tait, S. J., Feb 2002, In : Clinical Science. 102, 2, p. 233-240 8 p.

    Research output: Contribution to journalArticle

    50 Citations (Scopus)

    Metal- and tissue-dependent relationship between metallothionein mRNA and protein

    Vasconcelos, M. H., Tam, S. C., Hesketh, J. E., Reid, M. & Beattie, J. H., 2002, In : Toxicology and Applied Pharmacology. 182, p. 91-97 7 p.

    Research output: Contribution to journalArticle

    35 Citations (Scopus)

    Metallothionein gene expression in human adipose tissue from lean and obese subjects

    Do, M. S., Nam, S. Y., Hong, S. E., Kim, K. W., Duncan, J. S., Beattie, J. H. & Trayhurn, P., Jun 2002, In : Hormone and Metabolic Research. 34, 6, p. 348-351 4 p.

    Research output: Contribution to journalArticle

    2001

    Lymphocyte metallothionein mRNA responds to marginal zinc intake in human volunteers (vol 84, pg 751, 2000)

    Allan, A. K., Hawksworth, G. M., Woodhouse, L. R., Sutherland, B., King, J. C. & Beattie, J. H., Feb 2001, In : British Journal of Nutrition. 85, 2, p. 247-247 1 p.

    Research output: Contribution to journalArticle

    801 Citations (Scopus)

    Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ

    Trayhurn, P. & Beattie, J. H., Aug 2001, In : Proceedings of the Nutrition Society. 60, 3, p. 329-339 11 p.

    Research output: Contribution to journalLiterature review

    10 Citations (Scopus)

    Selective extraction of blood plasma exchangeable copper for isotope studies of dietary copper absorption

    Beattie, J. H., Reid, M. D., Harvey, L. J., Dainty, J. R., Majsak-Newman, G. & Fairweather-Tait, S. J., 2001, In : Analyst. 126, 12, p. 2225-2229 5 p.

    Research output: Contribution to journalArticle