• 2319 Citations
20042020

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2020

Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells, H., Schelter, B. O., Bentham, P., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Wischik, D. J., Riedel, G., Gauthier, S., Jia, J., Moebius, H. J., Hardlund, J., Kipps, C. M., Kook, K., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 19 May 2020, In : Journal of Alzheimer's Disease. 75, 2, p. 501-519 19 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
1 Downloads (Pure)

Hydrogen bonding and the design of twist-bend nematogens

Walker, R., Pociecha, D., Crawford, C. A., Storey, J. M. D., Gorecka, E. & Imrie, C. T., Apr 2020, In : Journal of molecular liquids. 303, 9 p., 112630.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Molecular structure and the twist-bend nematic phase: the role of terminal chains

Abberley, J. P., Walker, R., Storey, J. M. D. & Imrie, C. T., 9 Jul 2020, In : Liquid Crystals. 47, 8, p. 1232–1245 14 p.

Research output: Contribution to journalArticle

Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain

Al-Hilaly, Y. K., Foster, B. E., Biasetti, L., Lutter, L., Pollack, S. J., Rickard, J. E., Storey, J. M. D., Harrington, C. R., Xue, W-F., Wischik, C. M. & Serpell, L. C., Mar 2020, In : FEBS LETTERS. 594, 5, p. 944-950 7 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
2 Downloads (Pure)

Twist-Bend Nematogenic Supramolecular Dimers and Trimers Formed by Hydrogen Bonding

Walker, R., Pociecha, D., Martinez-Felipe, A., Storey, J. MD., Gorecka, E. & Imrie, C. T., Mar 2020, In : Crystals. 10, 3, 16 p., 175.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
4 Downloads (Pure)
2019

Augmenting Bragg Reflection with Polymer-sustained Conical Helix

Joshi, V., Paterson, D. A., Storey, J. M. D., Imrie, C. T. & Chien, L. C., 2 Apr 2019, In : Scientific Reports. 9, 5468.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
7 Downloads (Pure)

Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

Schelter, B. O., Shiells, H. C., Baddeley, T. C., Rubino, C. M., Ganesan, H., Hammel, J., Vuksanovic, V., Staff, R. T., Murray, A. D., Bracoud, L., Riedel, G., Gauthier, S., Jia, J., Bentham, P., Kook, K., Storey, J. M. D., Harrington, C. R. & Wischik, C. M., 26 Nov 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 931-946 16 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
6 Downloads (Pure)

Distinct differences in the nanoscale behaviors of the twist-bend liquid crystal phase of a flexible linear trimer and homologous dimer

Tuchband, M. R., Paterson, D. A., Salamończyk, M., Norman, V. A., Scarbrough, A. N., Forsyth, E., Garcia, E., Wang, C., Storey, J. M. D., Walba, D. M., Sprunt, S., Jákli, A., Zhu, C., Imrie, C. T. & Clark, N. A., 28 May 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 10698-10704 7 p.

Research output: Contribution to journalArticle

Open Access
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15 Citations (Scopus)
5 Downloads (Pure)

Fast-and-Giant Photorheological Effect in a Liquid Crystal Dimer

Aya, S., Salamon, P., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Araoka, F., Jákli, A. & Buka, Á., May 2019, In : Advanced Materials Interfaces. 6, 9, 7 p., 1802032.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
2 Downloads (Pure)

High-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal

Aya, S., Salamon, P., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Araoka, F., Jákli, A. & Buka, Á., 31 Oct 2019, In : Journal of visualized experiments : JoVE. 152, e60433.

Research output: Contribution to journalArticle

Open Access
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20 Citations (Scopus)
3 Downloads (Pure)

Multi-level chirality in liquid crystals formed by achiral molecules

Salamończyk, M., Vaupotič, N., Pociecha, D., Walker, R., Storey, J. M. D., Imrie, C. T., Wang, C., Zhu, C. & Gorecka, E., 23 Apr 2019, In : Nature Communications. 10, 1922.

Research output: Contribution to journalArticle

Open Access
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27 Citations (Scopus)
8 Downloads (Pure)

Spherical-cap droplets of a photo-responsive bent liquid crystal dimer

Yoshioka, J., Salamon, P., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Jákli, A., Araoka, F. & Buka, A., 7 Feb 2019, In : Soft matter. 15, 5, p. 989-998 10 p.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
2 Downloads (Pure)

Structure-property relationships in azobenzene-based twist-bend nematogens

Abberley, J. P., Storey, J. M. D. & Imrie, C. T., 2019, In : Liquid Crystals. 46, 13-14, p. 2102-2114 13 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)

Sulfur-linked cyanobiphenyl-based liquid crystal dimers and the twist-bend nematic phase

Cruickshank, E., Salamończyk, M., Pociecha, D., Strachan, G. J., Storey, J. M. D., Wang, C., Feng, J., Zhu, C., Gorecka, E. & Imrie, C. T., 9 Aug 2019, In : Liquid Crystals. 46, 10, p. 1595-1609 15 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)

The Chiral Twist-Bend Nematic Phase (N*TB)

Walker, R., Pociecha, D., Storey, J. M. D., Gorecka, E. & Imrie, C. T., 17 Oct 2019, In : Chemistry : a European Journal. 25, 58, p. 13329-13335 7 p.

Research output: Contribution to journalArticle

Open Access
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13 Citations (Scopus)
2018
Open Access
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9 Citations (Scopus)
13 Downloads (Pure)

Cholesteric Metronomes with Flexoelectrically Programmable Amplitude

Joshi, V., Chang, K. H., Varanytsia, A., Paterson, D. A., Storey, J. M. D., Imrie, C. T. & Chien, L. C., 19 Jun 2018, In : Advanced Optical Materials. 6, 12, 1800013.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Critical behavior of the optical birefringence at the nematic to twist bend nematic phase transition

Pociecha, D., Crawford, C. A., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Vaupotič, N. & Gorecka, E., 26 Nov 2018, In : Physical Review. E, Statistical, Nonlinear and Soft Matter Physics. 98, 5, p. 1-5 5 p., 052706.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
6 Downloads (Pure)

Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)

Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In : Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
10 Downloads (Pure)

Heliconical smectic phases formed by achiral molecules

Abberley, J. P., Killah, R., Walker, R., Storey, J. M. D., Imrie, C. T., Salamończyk, M., Zhu, C., Gorecka, E. & Pociecha, D., 15 Jan 2018, In : Nature Communications. 9, 228.

Research output: Contribution to journalArticle

Open Access
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73 Citations (Scopus)
10 Downloads (Pure)
Open Access
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9 Citations (Scopus)
14 Downloads (Pure)

Spontaneous chirality through mixing achiral components: A twist-bend nematic phase driven by hydrogen-bonding between unlike components

Walker, R., Pociecha, D., Abberley, J. P., Martinez-Felipe, A., Paterson, D. A., Forsyth, E., Lawrence, G., Henderson, P. A., Storey, J. M. D., Gorecka, E. & Imrie, C. T., 7 Apr 2018, In : Chemical Communications. 54, 27, p. 3383-3386 4 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
36 Citations (Scopus)
2017

Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking

Al-Hilaly, Y. K., Pollack, S. J., Vadukul, D., Citossi, F., Rickard, J. E., Simpson, M., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 24 Nov 2017, In : Journal of Molecular Biology. 429, 23, p. 3650-3665 16 p.

Research output: Contribution to journalArticle

Open Access
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18 Citations (Scopus)
16 Downloads (Pure)

Azobenzene-based liquid crystal dimers and the twist-bend nematic phase

Paterson, D. A., Walker, R., Abberley, J. P., Forestier, J., Harrison, W. T. A., Storey, J. M. D., Pociecha, D., Gorecka, E. & Imrie, C. T., 21 Oct 2017, In : Liquid Crystals. 44, 12-13, p. 2060-2078 19 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Cyanobiphenyl-based liquid crystal dimers and the twist-bend nematic phase

Paterson, D. A., Abberley, J. P., Harrison, W. T. A., Storey, J. & Imrie, C. T., 2017, In : Liquid Crystals. 44, 1, p. 127-146 20 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial

Wilcock, G. K., Gauthier, S., Frisoni, G. B., Jia, J., Hardlund, J. H., Moebius, H. J., Bentham, P., Kook, K. A., Schelter, B. O., Wischik, D. J., Davis, C. S., Staff, R. T., Vuksanovic, V., Ahearn, T., Bracoud, L., Shamsi, K., Marek, K., Seibyl, J., Riedel, G., Storey, J. M. D. & 2 others, Harrington, C. R. & Wischik, C. M., 28 Nov 2017, In : Journal of Alzheimer's Disease. 61, 1, p. 435-457 24 p.

Research output: Contribution to journalArticle

Open Access
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36 Citations (Scopus)
28 Downloads (Pure)

Structure–property relationships in twist-bend nematogens: the influence of terminal groups

Abberley, J. P., Jansze, S. M., Walker, R., Paterson, D. A., Henderson, P. A., Marcelis, A. T. M., Storey, J. M. D. & Imrie, C. T., 2017, In : Liquid Crystals. 44, 1, p. 68-83 16 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Tunable backflow in chiral nematic liquid crystals via twist-bend nematogens and surface-localised in-situ polymer protrusions

Joshi, V., Paterson, D. A., Storey, J. M. D., Imrie, C. T. & Chien, L. C., 2017, In : Liquid Crystals. 44, 14-15, p. 2327-2336 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016
Open Access
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42 Citations (Scopus)
6 Downloads (Pure)
3 Citations (Scopus)
11 Downloads (Pure)

Different N—H···π interactions in two indole derivatives

Kerr, J. R., Trembleau, L., Storey, J. M. D., Wardell, J. L. & Harrison, W. T. A., May 2016, In : Acta Crystallographica Section E: Crystallographic Communications. 72, 5, p. 699-703 5 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
6 Downloads (Pure)

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial

Gauthier, S., Feldman, H. H., Schneider, L. S., Wilcock, G. K., Frisoni, G. B., Hardlund, J. H., Moebius, H. J., Bentham, P., Kook, K. A., Wischik, D. J., Schelter, B. O., Davis, C. S., Staff, R. T., Bracoud, L., Shamsi, K., Storey, J. M. D., Harrington, C. R. & Wischik, C. M., Dec 2016, In : The Lancet. 388, 10062, p. 2873-2884 12 p.

Research output: Contribution to journalArticle

Open Access
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134 Citations (Scopus)
8 Downloads (Pure)

Electrically tunable laser based on oblique heliconical cholesteric liquid crystal

Xiang, J., Varanytsia, A., Minkowski, F., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Lavrentovich, O. D. & Palffy-Muhoray, P., 15 Nov 2016, In : PNAS. 113, 46, p. 12925-12928 4 p.

Research output: Contribution to journalArticle

Open Access
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65 Citations (Scopus)
8 Downloads (Pure)

Ethyl 2-(5-bromo-2-iodo­anilino)cyclo­pent-1-ene-1-carboxyl­ate

Barnes, P., Storey, J. M. D. & Harrison, W. T. A., Jan 2016, In : IUCrData. 1, 1, p. 1-7 7 p., x152178.

Research output: Contribution to journalArticle

Open Access
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7 Downloads (Pure)
Open Access
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7 Downloads (Pure)

Magnetically tunable selective reflection of light by heliconical cholesterics

Salili, S. M., Xiang, J., Wang, H., Li, Q., Paterson, D. A., Storey, J. M. D., Imrie, C. T., Lavrentovich, O. D., Sprunt, S. N., Gleeson, J. T. & Jákli, A., 21 Oct 2016, In : Physical Review. E, Statistical, Nonlinear and Soft Matter Physics. 94, 4, 042705.

Research output: Contribution to journalArticle

Open Access
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29 Citations (Scopus)
7 Downloads (Pure)

Reversible Isothermal Twist-Bend Nematic-Nematic Phase Transition Driven by the Photoisomerization of an Azobenzene-Based Nonsymmetric Liquid Crystal Dimer

Paterson, D. A., Xiang, J., Singh, G., Walker, R., Agra-Kooijman, D. M., Martinez-Felipe, A., Gao, M., Storey, J. M. D., Kumar, S., Lavrentovich, O. D. & Imrie, C. T., 27 Apr 2016, In : Journal of the American Chemical Society. 138, 16, p. 5283-5289 7 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Understanding the twist-bend nematic phase: the characterisation of 1-(4-cyanobiphenyl-4'-yloxy)-6-(4-cyanobiphenyl-4'-yl) hexane (CB6OCB) and comparison with CB7CB

Paterson, D. A., Gao, M., Kim, Y-K., Jamali, A., Finley, K., Robles-Hernandez, B., Diez-Berat, S., Salud, J., de la Fuente, M. R., Timimi, B. A., Zimmermann, H., Greco, C., Ferrarini, A., Storey, J. M. D., Lopez, D. O., Lavrentovich, O. D., Luckhurst, G. R. & Imrie, C. T., 2016, In : Soft matter. 12, 32, p. 6827-6840 14 p.

Research output: Contribution to journalArticle

Open Access
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95 Citations (Scopus)
8 Downloads (Pure)
Open Access
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1 Citation (Scopus)
7 Downloads (Pure)
2015

A Twist-Bend Nematic Phase Driven by Hydrogen Bonding

Jansze, S. M., Martinez-Felipe, A., Storey, J. M. D., Marcelis, A. T. M. & Imrie, C. T., 7 Jan 2015, In : Angewandte Chemie International Edition. 54, 2, p. 643-646 4 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)
Open Access
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48 Citations (Scopus)
10 Downloads (Pure)
66 Citations (Scopus)
Open Access
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4 Citations (Scopus)
11 Downloads (Pure)

Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models

Melis, V., Magbagbeolu, M., Rickard, J. E., Horsley, D., Davidson, K., Harrington, K. A., Goatman, K., Goatman, E. A., Deiana, S., Close, S. P., Zabke, C., Stamer, K., Dietze, S., Schwab, K., Storey, J. M. D., Harrington, C. R., Wischik, C. M., Theuring, F. & Riedel, G., Jun 2015, In : Behavioural Pharmacology. 26, 4, p. 353-368 16 p.

Research output: Contribution to journalArticle

Open Access
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43 Citations (Scopus)
11 Downloads (Pure)

Electrically Tunable Selective Reflection of Light from Ultraviolet to Visible and Infrared by Heliconical Cholesterics

Xiang, J., Li, Y., Li, Q., Paterson, D. A., Storey, J. M. D., Imrie, C. T. & Lavrentovich, O. D., 20 May 2015, In : Advanced Materials. 27, 19, p. 3014-3018 5 p.

Research output: Contribution to journalArticle

Open Access
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143 Citations (Scopus)
8 Downloads (Pure)

New insights into the liquid crystal behaviour of hydrogen-bonded mixtures provided by temperature-dependent FTIR spectroscopy

Paterson, D. A., Martinez-Felipe, A., Jansze, S. M., Marcelis, A. T. M., Storey, J. M. D. & Imrie, C. T., 2015, In : Liquid Crystals. 42, 5-6, p. 928-939 12 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Tau Aggregation Inhibitor Therapy: An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease

Wischik, C. M., Staff, R. T., Wischik, D. J., Bentham, P., Murray, A. D., Storey, J. M. D., Kook, K. A. & Harrington, C. R., 22 Jan 2015, In : Journal of Alzheimer's Disease. 44, 2, p. 705-720 16 p.

Research output: Contribution to journalArticle

Open Access
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141 Citations (Scopus)
6 Downloads (Pure)
2014

Tau-aggregation inhibitor therapy for Alzheimer's disease

Wischik, C. M., Harrington, C. R. & Storey, J. M. D., 15 Apr 2014, In : Biochemical Pharmacology. 88, 4, p. 529-539 11 p.

Research output: Contribution to journalArticle

Open Access
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154 Citations (Scopus)
7 Downloads (Pure)