Julie Brittenden

Professor

    • 1797 Citations
    1992 …2019

    Research output per year

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    Personal profile

    Research Interests:

    • Deputy lead of division of applied medicine (2011-)
    • University Academic lead for MHRA activites (2011)-Chair Clinical studies Oversight Group,  oversee that processes/SOPS/ structures  are in place to ensure compliance with regulations, provide medical advice when a SAE/ SUSAR/serious breech is notified, to contribute to the different groups established to ensure the highest quality CTIMPS 
    • Clinical Advisor to CHART (2009-2010)-advise on the suitability of clinical trials and liaise between the unit and clinicians.
    • Lead ofInstitute ofMedical Science Vascular research programmes (2006-), Division (2007-2009)
    • Deputy lead: Cardiovascular research programme (2010-)
    • Lead of NHS Vascular research programmes (2007-, Co-Lead 2005-2007)

    My research interests are in cardiovascular biomarkers, platelet and endothelial function, plaque instability and the management of venous diseases.

    National roles include: Member of the Research Council of the Vascular Society of Great Britain & Ireland, Council member of Venous Forum, Facualty Member of Charing Cross International Vascular Symposium, Advisor on NHS research priorities to HTA interventional procedures panel

    Teaching Responsibilities:

    I am Asessment co-ordinator for the Medical school, University of Aberdeen. 

    National interests include: ¿member of the PLAB board ¿¿responsible for developing, analysing and reviewing assessment in medicine (2006-¿)¿¿;¿¿¿¿¿¿¿¿¿ ex¿¿ternal examin¿¿e¿r¿¿¿ for the final year medicine at the Universities of Leeds and Dundee.

    Other Interests:

     National interests include: Vascular Surgery Advisor to the Scottish Chief Medical Officer, member of the Scottish Medical and Advisory Committee, member of the Scottish National Aortic Aneurysm Screening Implementation Group and Work Delivery Group, Chairperson of SIGN guidelines on management of Venous ulcers and critiscm editor for Cochrane Peripheral arterial disease group

    Qualifications:

    FRCS (Glasgow): 1994

    MD with Honours (University of Aberdeen):1995

    FRCS intercollegiate (Gold medal):2000

    Research Overview:

    The main findings of our research to date are

    1) Patients with peripheral arterial disease have a prothrombotic state which may predispose to their increased risk of cardiovascular morbidity and mortality

    2) routine treatment such as surgery may exacebate this prothrombotic state and contribute to to the post-operative cardiovascular complications seen in these patients

    3) Platelet activity increases with the severity of the disease suggesting the need for more aggresive anti-platelet therapy in patients with severe disease

    4)Aspirin non-responsiveness increases post-operatively and predisposes to post-operative myocardial injury

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    Research Output

    Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

    Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J. & 1 others, Campbell, M. K., 5 Sep 2019, In : The New England Journal of Medicine. 381, 10, p. 912-922 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 12 Citations (Scopus)
    5 Downloads (Pure)

    Behavioural recovery after treatment for varicose veins

    Cotton, S. C., MacLennan, G., Brittenden, J., Prior, M. & Francis, J., Mar 2016, In : British Journal of Surgery. 103, 4, p. 374-381 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 8 Citations (Scopus)
    6 Downloads (Pure)

    Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

    Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M. & 2 others, Bolsover, D. & Campbell, M. K., Apr 2015, In : Health Technology Assessment. 19, 27, p. 1-342 342 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 43 Citations (Scopus)
    16 Downloads (Pure)

    Increased levels of Symmetric dimethyl-arginine are associated with all-cause mortality in patients with symptomatic peripheral arterial disease

    Staniszewska, A., Rajagopalan, S., Al-Shaheen, A., Thies, F. & Brittenden, J., Feb 2015, In : British Journal of Surgery. 102, p. 4-4 1 p.

    Research output: Contribution to journalAbstract

    56 Citations (Scopus)

    Increased levels of Symmetric dimethyl-arginine are associated with all-cause mortality in patients with symptomatic peripheral arterial disease

    Staniszewska, A., Rajagopalan, S., Al-Shaheen, A., Thies, F. & Brittenden, J., May 2015, In : Journal of Vascular Surgery. 61, 5, p. 1292-1298 7 p.

    Research output: Contribution to journalArticle

    Open Access
  • 6 Citations (Scopus)