• 6321 Citations
19952019
If you made any changes in Pure these will be visible here soon.

Research Output 1995 2019

2019

Developments in understanding and applying prebiotics in research and practice: an ISAPP conference paper

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A., Tang, M. L. K., Lee, J. C-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. & Gibson, G. R., 12 Sep 2019, In : Journal of Applied Microbiology.

Research output: Contribution to journalArticle

Open Access
Prebiotics
Insurance Benefits
Research
Literature
Food Industry

Heterologous gene expression in the human gut bacteria Eubacterium rectale and Roseburia inulinivorans by means of conjugative plasmids

Sheridan, P. O., Martin, J. C., Minton, N. P., Flint, H. J., O'Toole, P. W. & Scott, K. P., 1 Oct 2019, In : Anaerobe. 59, p. 131-140 10 p.

Research output: Contribution to journalArticle

Eubacterium
Plasmids
Bacteria
Gene Expression
Genetic Vectors
Dementia
Behavioral Symptoms
Brain
Psychology
Gastrointestinal Microbiome

The impact of antimicrobials on gut bacteria: an interview with Karen Scott

Scott, K. P., Sep 2019, In : Future Microbiology. 14, 13, p. 1081-1082 2 p.

Research output: Contribution to journalArticle

2018
178 Citations (Scopus)
8 Downloads (Pure)

Gut microbiota functions: metabolism of nutrients and other food components

Rowland, I., Gibson, G., Heinken, A., Scott, K., Swann, J., Thiele, I. & Tuhoy, K., Feb 2018, In : European Journal of Nutrition. 57, 1, p. 1-24 24 p.

Research output: Contribution to journalArticle

Open Access
File
Food
Dietary Carbohydrates
Plant Proteins
Volatile Fatty Acids
Health
2017
8 Citations (Scopus)
11 Downloads (Pure)

16S sequencing and functional analysis of the fecal microbiome during treatment of newly diagnosed pediatric inflammatory bowel disease

Ashton, J. J., Colquhoun, C. M., Cleary, D. W. ., Coelho, T., Haggarty, R., Mulder, I., Batra, A., Afzal, N. A., Beattie, R. M., Scott, K. P. & Ennis, S., Jun 2017, In : Medicine. 96, 26, p. 1-10 10 p., e7347.

Research output: Contribution to journalArticle

Open Access
File
Microbiota
Inflammatory Bowel Diseases
Pediatrics
Siblings
Crohn Disease
511 Citations (Scopus)
7 Downloads (Pure)

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Gibson, G. R., Hutkins, R., Sanders, M. E., Prescott, S. L., Reimer, R. A., Salminen, S. J., Scott, K., Stanton, C., Swanson, K. S., Cani, P. D., Verbeke, K. & Reid, G., 2017, In : Nature Reviews Gastroenterology & Hepatology. 14, p. 491-502 12 p.

Research output: Contribution to journalArticle

Open Access
File
Prebiotics
Probiotics
Microbiota
Insurance Benefits
Health
12 Citations (Scopus)
5 Downloads (Pure)

Strain-level metagenomic analysis of the fermented dairy beverage nunu highlights potential food safety risks

Walsh, A. M., Crispie, F., Daari, K., O’Sullivan, O., Martin, J. C., Arthur, C. T., Claesson, M. J., Scott, K. P. & Cotter, P. D., Aug 2017, In : Applied and Environmental Microbiology. 83, 16, 28 p., e01144-17.

Research output: Contribution to journalArticle

Open Access
File
Metagenome
Metagenomics
food safety
Food Safety
Beverages
12 Citations (Scopus)
4 Downloads (Pure)

The agronomic performance and nutritional content of oat and barley varieties grown in a northern maritime environment depends on variety and growing conditions

Chappell, A., Scott, K. P., Griffiths, I. A., Cowan, A. A., Hawes, C., Wishart, J. & Martin, P., Mar 2017, In : Journal of Cereal Science. 74, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
Glucans
Hordeum
agronomic traits
Crops
oats
100 Citations (Scopus)

Towards standards for human fecal sample processing in metagenomic studies

Costea, P. I., Zeller, G., Sunagawa, S., Pelletier, E., Alberti, A., Levenez, F., Tramontano, M., Driessen, M., Hercog, R., Jung, F-E., Kultima, J. R., Hayward, M. R., Coelho, L. P., Allen-Vercoe, E., Bertrand, L., Blaut, M., Brown, J. R. M., Carton, T., Cools-Portier, S., Daigneault, M. & 38 others, Derrien, M., Druesne, A., de Vos, W. M., Finlay, B. B., Flint, H. J., Guarner, F., Hattori, M., Heilig, H., Luna, R. A., van Hylckama Vlieg, J., Junick, J., Klymiuk, I., Langella, P., Le Chatelier, E., Mai, V., Manichanh, C., Martin, J. C., Mery, C., Morita, H., O'Toole, P. W., Orvain, C., Patil, K. R., Penders, J., Persson, S., Pons, N., Popova, M., Salonen, A., Saulnier, D., Scott, K. P., Singh, B., Slezak, K., Veiga, P., Versalovic, J., Zhao, L., Zoetendal, E. G., Ehrlich, S. D., Dore, J. & Bork, P., 2017, In : Nature Biotechnology. 35, p. 1069–1076 8 p.

Research output: Contribution to journalArticle

Metagenomics
DNA
Processing
Microbiota
Gram-Negative Bacteria
45 Citations (Scopus)
5 Downloads (Pure)

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes

Sheridan, P. O., Martin, J. C., Lawley, T. D., Browne, H. P., Harris, H. M. B., Bernalier-Donadille, A., Duncan, S. H., O'Toole, P. W., Scott, K. P. & Flint, H. J., 9 Feb 2016, In : Microbial Genomics. 2, 2, p. 1-16 16 p., 43.

Research output: Contribution to journalArticle

Open Access
File
Firmicutes
butyrates
Roseburia
Eubacterium rectale
polysaccharides
2015
89 Citations (Scopus)
5 Downloads (Pure)

16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice

Walker, A. W., Martin, J. C., Scott, P., Parkhill, J., Flint, H. J. & Scott, K. P., 22 Jun 2015, In : Microbiome. 3, 26.

Research output: Contribution to journalArticle

Open Access
File
Bifidobacterium
rRNA Genes
Polymerase Chain Reaction
Feces
DNA
45 Citations (Scopus)

Altered Colonic Bacterial Fermentation as a Potential Pathophysiological Factor in Irritable Bowel Syndrome

Ringel-Kulka, T., Choi, C. H. W., Temas, D., Kim, A., Maier, D. M., Scott, K., Galanko, J. A. & Ringel, Y., 25 Aug 2015, In : The American journal of gastroenterology. 110, 9, p. 1339-1346 8 p.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Fermentation
Volatile Fatty Acids
Colon
Dysbiosis

Fermentation of oats (Avena sativa) by the faecal microbiota using an in vitro colonic fermentor system

Chappell, A. J., Thies, F., Martin, P., Flint, H. J. & Scott, K. P., 2015, In : Proceedings of the Nutrition Society. 74, OCE5, p. E302-E302 1 p.

Research output: Contribution to journalAbstract

52 Citations (Scopus)
4 Downloads (Pure)

First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota

Hansen, R., Scott, K. P., Khan, S., Martin, J. C., Berry, S. H., Stevenson, M., Okpapi, A., Munro, M. J. & Hold, G. L., 28 Jul 2015, In : PloS ONE. 10, 7, 10 p., e0133320.

Research output: Contribution to journalArticle

Open Access
File
Meconium
Microbiota
Enterococcaceae
Bacteria
neonates
222 Citations (Scopus)

Links between diet, gut microbiota composition and gut metabolism

Flint, H. J., Duncan, S. H., Scott, K. P. & Louis, P., Feb 2015, In : Proceedings of the Nutrition Society. 74, 1, p. 13-22 10 p.

Research output: Contribution to journalLiterature review

Butyrates
Microbiota
Propionates
Diet
Lactic Acid

Manipulating the gut microbiota to maintain health and treat disease

Scott, K. P., Antoine, J-M., Midtvedt, T. & van Hemert, S., 2015, In : Microbial Ecology in Health and Disease. 26, p. 25877

Research output: Contribution to journalArticle

Probiotics
Microbiota
Health
Prebiotics
Ruminococcus

The effect of in vitro fermentation of oats (Avena sativa) and barley (Hordeum vulgare) on the faecal gut microbiota

Chappell, A. J., Thies, F., Martin, P., Flint, H. J. & Scott, K. P., 15 Apr 2015, In : Proceedings of the Nutrition Society. 74, OCE1, p. E32-E32 1 p.

Research output: Contribution to journalAbstract

2 Citations (Scopus)

The Microbiota of the Human Gastrointestinal Tract: A Molecular View

Tuohy, K. M. & Scott, K. P., 2015, Diet-Microbe Interactions in the Gut: Effects on Human Health and Disease. Elsevier Inc., p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Microbiota
Gastrointestinal Tract
Metagenome
Metagenomics
Geography
2014
27 Citations (Scopus)

Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals?

Sheridan, P. O., Bindels, L. B., Saulnier, D. M., Reid, G., Nova, E., Holmgren, K., O'Toole, P. W., Bunn, J., Delzenne, N. & Scott, K. P., Jan 2014, In : Gut Microbes. 5, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

Open Access
Prebiotics
Probiotics
Microbiota
Malnutrition
Nutritional Status
12 Citations (Scopus)

Impact of a very low-energy diet on the fecal microbiota of obese individuals

Simões, C. D., Maukonen, J., Scott, K. P., Virtanen, K. A., Pietiläinen, K. H. & Saarela, M., Sep 2014, In : European Journal of Nutrition. 53, 6, p. 1421-1429 9 p.

Research output: Contribution to journalArticle

Microbiota
Fluorescence In Situ Hybridization
Diet
Weights and Measures
Denaturing Gradient Gel Electrophoresis
257 Citations (Scopus)

Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

Reichardt, N., Duncan, S. H., Young, P., Belenguer, A., McWilliam Leitch, C., Scott, K. P., Flint, H. J. & Louis, P., Jun 2014, In : The ISME Journal. 8, 6, p. 1323-1335 13 p.

Research output: Contribution to journalArticle

Propionates
propionates
intestinal microorganisms
Coprococcus catus
phylogenetics
134 Citations (Scopus)

Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro

Scott, K. P., Martin, J. C., Duncan, S. H. & Flint, H. J., Jan 2014, In : FEMS Microbiology Ecology. 87, 1, p. 30-40 11 p.

Research output: Contribution to journalArticle

Prebiotics
Bifidobacterium
Butyrates
Bacteria
bacterium
2013
18 Citations (Scopus)
4 Downloads (Pure)

Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans

Neville, B. A., Sheridan, P. O., Harris, H. M. B., Coughlan, S., Flint, H. J., Duncan, S. H., Jeffery, I. B., Claesson, M. J., Ross, R. P., Scott, K. P. & O'Toole, P. W., 23 Jul 2013, In : PloS ONE. 8, 7, 15 p., e68919.

Research output: Contribution to journalArticle

Open Access
File
Flagellin
flagellin
Metagenome
Bacteria
Genes
369 Citations (Scopus)

The influence of diet on the gut microbiota

Scott, K. P., Gratz, S. W., Sheridan, P. O., Flint, H. J. & Duncan, S. H., Mar 2013, In : Pharmacological Research. 69, 1, p. 52-60 9 p.

Research output: Contribution to journalLiterature review

Diet
Fermentation
Dietary Carbohydrates
Butyrates
Colon
2012
10 Citations (Scopus)

Evaluation of novel assays to assess the influence of different iron sources on the growth of Clostridium difficile

Cernat, R. C. & Scott, K. P., Jun 2012, In : Anaerobe. 18, 3, p. 298-304 7 p.

Research output: Contribution to journalArticle

Clostridium difficile
Iron
Growth
Hemin
Lactoferrin
182 Citations (Scopus)

Functional dysbiosis within the intestinal microbiota of patients with irritable bowel syndrome

Chassard, C., Dapoingny, M., Scott, K. P., Crouzet, L., Del'homme, C., Marquet, P., Martin, J. C., Pikering, G., Ardid, D., Eschalier, A., Dubray, C., Flint, H. J. & Bernalier-Donadille, A., 2012, In : Alimentary Pharmacology & Therapeutics. 35, 7, p. 828-838 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
3 Downloads (Pure)

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

Bindels, L. B., Porporato, P., Dewulf, E. M., Verrax, J., Neyrinck, A. M., Martin, J. C., Scott, K. P., Buc Calderon, P., Feron, O., Muccioli, G. G., Sonveaux, P., Cani, P. D. & Delzenne, N. M., 9 Oct 2012, In : British Journal of Cancer. 107, 8, p. 1337-1344 8 p.

Research output: Contribution to journalArticle

Open Access
File
Fructans
Inulin
Propionates
Cell Proliferation
Volatile Fatty Acids
547 Citations (Scopus)

Microbial degradation of complex carbohydrates in the gut

Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P. & Forano, E., 1 Jul 2012, In : Gut Microbes. 3, 4, p. 289-306 18 p.

Research output: Contribution to journalLiterature review

Dietary Carbohydrates
Intestines
Verrucomicrobia
Carbohydrates
Bacteroidetes
67 Citations (Scopus)
6 Downloads (Pure)

Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model

Bindels, L., Beck, R., Schakman, O., Martin, J. C., de Backer, F., Sohet, F. M., Dewulf, E. M., Pachikian, B. D., Neyrinck, A. M., Thissen, J-P., Verrax, J., Buc Calderon, P., Pot, B., Grangette, C., Cani, P. D., Scott, K. P. & Delzenne, N., 27 Jun 2012, In : PloS ONE. 7, 6, 10 p., e37971.

Research output: Contribution to journalArticle

Open Access
File
muscular atrophy
Muscular Atrophy
Lactobacillus
leukemia
intestinal microorganisms
675 Citations (Scopus)

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P. & Duncan, S. H., Oct 2012, In : Nature Reviews Gastroenterology & Hepatology. 9, 10, p. 577-589 13 p.

Research output: Contribution to journalLiterature review

Large Intestine
Health
Diet
Gastrointestinal Diseases
Microbiota
2011
1 Citation (Scopus)

Micro-organisms in the human gut: diversity and function

Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., Aug 2011, In : The Biochemist. 33, 4, p. 4-9 5 p.

Research output: Contribution to journalLiterature review

Gastrointestinal Tract
Health
Chemical analysis
Research
21 Citations (Scopus)

Nutritional influences on the gut microbiota and the consequences for gastrointestinal health

Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., 1 Aug 2011, In : Biochemical Society Transactions. 39, 4, p. 1073-1078 6 p.

Research output: Contribution to journalLiterature review

Health
Lower Gastrointestinal Tract
Upper Gastrointestinal Tract
Microbiota
Chemical analysis
52 Citations (Scopus)

Optimization of a high-throughput CTAB-based protocol for the extraction of qPCR-grade DNA from rumen fluid, plant and bacterial pure cultures

Minas, K., Mcewan, N., Newbold, C. & Scott, K. P., Dec 2011, In : FEMS Microbiology Letters. 325, 2, p. 162-169 7 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Substrate-driven gene expression in Roseburia inulinivorans: Importance of inducible enzymes in the utilization of inulin and starch

Scott, K. P., Martin, J. C., Chassard, C., Clerget, M., Potrykus, J., Campbell, G. P., Mayer, C-D., Young, P., Rucklidge, G., Ramsay, A. G. & Flint, H. J., 15 Mar 2011, In : PNAS. 108, Supplement 1, p. 4672-4679 8 p.

Research output: Contribution to journalArticle

2009
62 Citations (Scopus)

Distribution of Tetracycline and Erythromycin Resistance Genes Among Human Oral and Fecal Metagenomic DNA

Seville, L. A., Patterson, A. J., Scott, K. P., Mullany, P., Quail, M. A., Parkhill, J., Ready, D., Wilson, M., Spratt, D. & Roberts, A. P., Sep 2009, In : Microbial Drug Resistance. 15, 3, p. 159-166 8 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Tetracycline resistome of the organic pig gut

Kazimierczak, K. A., Scott, K. P., Kelly, D. & Aminov, R. I., Mar 2009, In : Applied and Environmental Microbiology. 75, 6, p. 1717-1722 6 p.

Research output: Contribution to journalArticle

The Intestinal Microbiota of Irritable Bowel Syndrome Patients Is Characterized By Functional Dysbiosis

Chassard, C., Dapoigny, M. C., Scott, K. P., Del'Homme, C., Dubray, C., Eschalier, A., Flint, H. J., Bernalier-Donadille, A. & Flint, H. J., May 2009, In : Gastroenterology. 136, 5, Supplement 1, p. A214-A214 1 p.

Research output: Contribution to journalArticle

2008
30 Citations (Scopus)

A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones

Kazimierczak, K. A., Rincon, M. T., Patterson, A. J., Martin, J. C., Young, P., Flint, H. J. & Scott, K. P., Nov 2008, In : Antimicrobial Agents and Chemotherapy. 52, 11, p. 4001-4009 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Assessment of metabolic diversity within the intestinal microbiota from healthy humans using combined molecular and cultural approaches

Chassard, C., Scott, K. P., Marquet, P., Martin, J. C., Del'homme, C., Dapoigny, M., Flint, H. J. & Bernalier-Donadille, A., Dec 2008, In : FEMS Microbiology Ecology. 66, 3, p. 496-504 9 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Dietary fibre and the gut microbiota

Scott, K. P., Duncan, S. H. & Flint, H. J., Sep 2008, In : Nutrition Bulletin. 33, 3, p. 201-211 11 p.

Research output: Contribution to journalArticle

Dietary Fiber
Butyrates
Lactic Acid
Volatile Fatty Acids
Colon
4 Citations (Scopus)

Transfer of conjugative elements from rumen and human Firmicutes bacteria to Roseburia inulinivorans

Scott, K. P., Martin, J. C., Mrazek, J. & Flint, H. J., Jun 2008, In : Applied and Environmental Microbiology. 74, 12, p. 3915-3917 3 p.

Research output: Contribution to journalArticle

2007
10 Citations (Scopus)

Antibiotics and Resistance Genes: Influencing the Microbial Ecosystem in the Gut

Kazimierczak, K. A. & Scott, K. P., 2007, In : Advances in Applied Microbiology. 62, p. 269-292 24 p.

Research output: Contribution to journalLiterature review

Commensal bacteria in health and disease

Flint, H. J., Louis, P., Scott, K. P. & Duncan, S. H., Sep 2007, Virulence mechanisms of bacterial pathogens. Brogden, K. A., Minion, F. C., Cornick, N., Stanton, T. B., Zhang, Q., Nolan, L. K. & Wannemuehler, M. J. (eds.). 4 ed. ASM Press, p. 101-114 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

73 Citations (Scopus)

Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection

Patterson, A. J., Colangeli, R., Spigaglia, P. & Scott, K. P., Mar 2007, In : Environmental Microbiology. 9, 3, p. 703-715 13 p.

Research output: Contribution to journalArticle

348 Citations (Scopus)
32 Citations (Scopus)

Mosaic Tetracycline Resistance Genes Are Widespread in Human and Animal Fecal Samples

Patterson, A. J., Rincon, M. T., Flint, H. J. & Scott, K. P., Mar 2007, In : Antimicrobial Agents and Chemotherapy. 51, 3, p. 1115-1118 4 p.

Research output: Contribution to journalArticle