• 7313 Citations
19952020

Research output per year

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Research Output

2020

Developments in understanding and applying prebiotics in research and practice: an ISAPP conference paper

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A., Tang, M. L. K., Lee, J. C-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. & Gibson, G. R., Apr 2020, In : Journal of Applied Microbiology. 128, 4, p. 934-949 16 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019

Heterologous gene expression in the human gut bacteria Eubacterium rectale and Roseburia inulinivorans by means of conjugative plasmids

Sheridan, P. O., Martin, J. C., Minton, N. P., Flint, H. J., O'Toole, P. W. & Scott, K. P., 1 Oct 2019, In : Anaerobe. 59, p. 131-140 10 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
1 Downloads (Pure)

The impact of antimicrobials on gut bacteria: an interview with Karen Scott

Scott, K. P., Sep 2019, In : Future Microbiology. 14, 13, p. 1081-1082 2 p.

Research output: Contribution to journalArticle

2018

Gut microbiota functions: metabolism of nutrients and other food components

Rowland, I., Gibson, G., Heinken, A., Scott, K., Swann, J., Thiele, I. & Tuhoy, K., Feb 2018, In : European Journal of Nutrition. 57, 1, p. 1-24 24 p.

Research output: Contribution to journalArticle

Open Access
File
292 Citations (Scopus)
10 Downloads (Pure)
2017

16S sequencing and functional analysis of the fecal microbiome during treatment of newly diagnosed pediatric inflammatory bowel disease

Ashton, J. J., Colquhoun, C. M., Cleary, D. W. ., Coelho, T., Haggarty, R., Mulder, I., Batra, A., Afzal, N. A., Beattie, R. M., Scott, K. P. & Ennis, S., Jun 2017, In : Medicine. 96, 26, p. 1-10 10 p., e7347.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
13 Downloads (Pure)

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Gibson, G. R., Hutkins, R., Sanders, M. E., Prescott, S. L., Reimer, R. A., Salminen, S. J., Scott, K., Stanton, C., Swanson, K. S., Cani, P. D., Verbeke, K. & Reid, G., 2017, In : Nature Reviews Gastroenterology & Hepatology. 14, p. 491-502 12 p.

Research output: Contribution to journalArticle

Open Access
File
746 Citations (Scopus)
10 Downloads (Pure)

Strain-level metagenomic analysis of the fermented dairy beverage nunu highlights potential food safety risks

Walsh, A. M., Crispie, F., Daari, K., O’Sullivan, O., Martin, J. C., Arthur, C. T., Claesson, M. J., Scott, K. P. & Cotter, P. D., Aug 2017, In : Applied and Environmental Microbiology. 83, 16, 28 p., e01144-17.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
7 Downloads (Pure)

The agronomic performance and nutritional content of oat and barley varieties grown in a northern maritime environment depends on variety and growing conditions

Chappell, A., Scott, K. P., Griffiths, I. A., Cowan, A. A., Hawes, C., Wishart, J. & Martin, P., Mar 2017, In : Journal of Cereal Science. 74, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
8 Downloads (Pure)

Towards standards for human fecal sample processing in metagenomic studies

Costea, P. I., Zeller, G., Sunagawa, S., Pelletier, E., Alberti, A., Levenez, F., Tramontano, M., Driessen, M., Hercog, R., Jung, F-E., Kultima, J. R., Hayward, M. R., Coelho, L. P., Allen-Vercoe, E., Bertrand, L., Blaut, M., Brown, J. R. M., Carton, T., Cools-Portier, S., Daigneault, M. & 38 others, Derrien, M., Druesne, A., de Vos, W. M., Finlay, B. B., Flint, H. J., Guarner, F., Hattori, M., Heilig, H., Luna, R. A., van Hylckama Vlieg, J., Junick, J., Klymiuk, I., Langella, P., Le Chatelier, E., Mai, V., Manichanh, C., Martin, J. C., Mery, C., Morita, H., O'Toole, P. W., Orvain, C., Patil, K. R., Penders, J., Persson, S., Pons, N., Popova, M., Salonen, A., Saulnier, D., Scott, K. P., Singh, B., Slezak, K., Veiga, P., Versalovic, J., Zhao, L., Zoetendal, E. G., Ehrlich, S. D., Dore, J. & Bork, P., 2017, In : Nature Biotechnology. 35, p. 1069–1076 8 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes

Sheridan, P. O., Martin, J. C., Lawley, T. D., Browne, H. P., Harris, H. M. B., Bernalier-Donadille, A., Duncan, S. H., O'Toole, P. W., Scott, K. P. & Flint, H. J., 9 Feb 2016, In : Microbial Genomics. 2, 2, p. 1-16 16 p., 43.

Research output: Contribution to journalArticle

Open Access
File
57 Citations (Scopus)
7 Downloads (Pure)
2015

16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice

Walker, A. W., Martin, J. C., Scott, P., Parkhill, J., Flint, H. J. & Scott, K. P., 22 Jun 2015, In : Microbiome. 3, 26.

Research output: Contribution to journalArticle

Open Access
File
102 Citations (Scopus)
7 Downloads (Pure)

Altered Colonic Bacterial Fermentation as a Potential Pathophysiological Factor in Irritable Bowel Syndrome

Ringel-Kulka, T., Choi, C. H. W., Temas, D., Kim, A., Maier, D. M., Scott, K., Galanko, J. A. & Ringel, Y., 25 Aug 2015, In : The American journal of gastroenterology. 110, 9, p. 1339-1346 8 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Fermentation of oats (Avena sativa) by the faecal microbiota using an in vitro colonic fermentor system

Chappell, A. J., Thies, F., Martin, P., Flint, H. J. & Scott, K. P., 2015, In : Proceedings of the Nutrition Society. 74, OCE5, p. E302-E302 1 p.

Research output: Contribution to journalAbstract

First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota

Hansen, R., Scott, K. P., Khan, S., Martin, J. C., Berry, S. H., Stevenson, M., Okpapi, A., Munro, M. J. & Hold, G. L., 28 Jul 2015, In : PloS ONE. 10, 7, 10 p., e0133320.

Research output: Contribution to journalArticle

Open Access
File
66 Citations (Scopus)
6 Downloads (Pure)

Links between diet, gut microbiota composition and gut metabolism

Flint, H. J., Duncan, S. H., Scott, K. P. & Louis, P., Feb 2015, In : Proceedings of the Nutrition Society. 74, 1, p. 13-22 10 p.

Research output: Contribution to journalLiterature review

284 Citations (Scopus)

Manipulating the gut microbiota to maintain health and treat disease

Scott, K. P., Antoine, J-M., Midtvedt, T. & van Hemert, S., 2015, In : Microbial Ecology in Health and Disease. 26, p. 25877

Research output: Contribution to journalArticle

The effect of in vitro fermentation of oats (Avena sativa) and barley (Hordeum vulgare) on the faecal gut microbiota

Chappell, A. J., Thies, F., Martin, P., Flint, H. J. & Scott, K. P., 15 Apr 2015, In : Proceedings of the Nutrition Society. 74, OCE1, p. E32-E32 1 p.

Research output: Contribution to journalAbstract

The Microbiota of the Human Gastrointestinal Tract: A Molecular View

Tuohy, K. M. & Scott, K. P., 2015, Diet-Microbe Interactions in the Gut: Effects on Human Health and Disease. Elsevier Inc., p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Can prebiotics and probiotics improve therapeutic outcomes for undernourished individuals?

Sheridan, P. O., Bindels, L. B., Saulnier, D. M., Reid, G., Nova, E., Holmgren, K., O'Toole, P. W., Bunn, J., Delzenne, N. & Scott, K. P., Jan 2014, In : Gut Microbes. 5, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)

Impact of a very low-energy diet on the fecal microbiota of obese individuals

Simões, C. D., Maukonen, J., Scott, K. P., Virtanen, K. A., Pietiläinen, K. H. & Saarela, M., Sep 2014, In : European Journal of Nutrition. 53, 6, p. 1421-1429 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

Reichardt, N., Duncan, S. H., Young, P., Belenguer, A., McWilliam Leitch, C., Scott, K. P., Flint, H. J. & Louis, P., Jun 2014, In : The ISME Journal. 8, 6, p. 1323-1335 13 p.

Research output: Contribution to journalArticle

310 Citations (Scopus)

Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro

Scott, K. P., Martin, J. C., Duncan, S. H. & Flint, H. J., Jan 2014, In : FEMS Microbiology Ecology. 87, 1, p. 30-40 11 p.

Research output: Contribution to journalArticle

160 Citations (Scopus)
2013

Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans

Neville, B. A., Sheridan, P. O., Harris, H. M. B., Coughlan, S., Flint, H. J., Duncan, S. H., Jeffery, I. B., Claesson, M. J., Ross, R. P., Scott, K. P. & O'Toole, P. W., 23 Jul 2013, In : PloS ONE. 8, 7, 15 p., e68919.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
6 Downloads (Pure)

The influence of diet on the gut microbiota

Scott, K. P., Gratz, S. W., Sheridan, P. O., Flint, H. J. & Duncan, S. H., Mar 2013, In : Pharmacological Research. 69, 1, p. 52-60 9 p.

Research output: Contribution to journalLiterature review

432 Citations (Scopus)
2012

Evaluation of novel assays to assess the influence of different iron sources on the growth of Clostridium difficile

Cernat, R. C. & Scott, K. P., Jun 2012, In : Anaerobe. 18, 3, p. 298-304 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Functional dysbiosis within the intestinal microbiota of patients with irritable bowel syndrome

Chassard, C., Dapoingny, M., Scott, K. P., Crouzet, L., Del'homme, C., Marquet, P., Martin, J. C., Pikering, G., Ardid, D., Eschalier, A., Dubray, C., Flint, H. J. & Bernalier-Donadille, A., 2012, In : Alimentary Pharmacology & Therapeutics. 35, 7, p. 828-838 11 p.

Research output: Contribution to journalArticle

193 Citations (Scopus)

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

Bindels, L. B., Porporato, P., Dewulf, E. M., Verrax, J., Neyrinck, A. M., Martin, J. C., Scott, K. P., Buc Calderon, P., Feron, O., Muccioli, G. G., Sonveaux, P., Cani, P. D. & Delzenne, N. M., 9 Oct 2012, In : British Journal of Cancer. 107, 8, p. 1337-1344 8 p.

Research output: Contribution to journalArticle

Open Access
File
121 Citations (Scopus)
5 Downloads (Pure)

Microbial degradation of complex carbohydrates in the gut

Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P. & Forano, E., 1 Jul 2012, In : Gut Microbes. 3, 4, p. 289-306 18 p.

Research output: Contribution to journalLiterature review

647 Citations (Scopus)

Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model

Bindels, L., Beck, R., Schakman, O., Martin, J. C., de Backer, F., Sohet, F. M., Dewulf, E. M., Pachikian, B. D., Neyrinck, A. M., Thissen, J-P., Verrax, J., Buc Calderon, P., Pot, B., Grangette, C., Cani, P. D., Scott, K. P. & Delzenne, N., 27 Jun 2012, In : PloS ONE. 7, 6, 10 p., e37971.

Research output: Contribution to journalArticle

Open Access
File
84 Citations (Scopus)
8 Downloads (Pure)

The role of the gut microbiota in nutrition and health

Flint, H. J., Scott, K. P., Louis, P. & Duncan, S. H., Oct 2012, In : Nature Reviews Gastroenterology & Hepatology. 9, 10, p. 577-589 13 p.

Research output: Contribution to journalLiterature review

766 Citations (Scopus)
2011

Micro-organisms in the human gut: diversity and function

Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., Aug 2011, In : The Biochemist. 33, 4, p. 4-9 5 p.

Research output: Contribution to journalLiterature review

1 Citation (Scopus)

Nutritional influences on the gut microbiota and the consequences for gastrointestinal health

Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., 1 Aug 2011, In : Biochemical Society Transactions. 39, 4, p. 1073-1078 6 p.

Research output: Contribution to journalLiterature review

22 Citations (Scopus)

Optimization of a high-throughput CTAB-based protocol for the extraction of qPCR-grade DNA from rumen fluid, plant and bacterial pure cultures

Minas, K., Mcewan, N., Newbold, C. & Scott, K. P., Dec 2011, In : FEMS Microbiology Letters. 325, 2, p. 162-169 7 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Probiotic and prebiotic claims in Europe: Seeking a clear roadmap

Guarner, F., Sanders, M. E., Gibson, G., Klaenhammer, T., Cabana, M., Scott, K., Reid, G., Delzenne, N. M., Fahey, G. C. & Hill, C., 14 Dec 2011, In : British Journal of Nutrition. 106, 11, p. 1765-1767 3 p.

Research output: Contribution to journalLetter

15 Citations (Scopus)

Substrate-driven gene expression in Roseburia inulinivorans: Importance of inducible enzymes in the utilization of inulin and starch

Scott, K. P., Martin, J. C., Chassard, C., Clerget, M., Potrykus, J., Campbell, G. P., Mayer, C-D., Young, P., Rucklidge, G., Ramsay, A. G. & Flint, H. J., 15 Mar 2011, In : PNAS. 108, Supplement 1, p. 4672-4679 8 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)
2009

Distribution of Tetracycline and Erythromycin Resistance Genes Among Human Oral and Fecal Metagenomic DNA

Seville, L. A., Patterson, A. J., Scott, K. P., Mullany, P., Quail, M. A., Parkhill, J., Ready, D., Wilson, M., Spratt, D. & Roberts, A. P., Sep 2009, In : Microbial Drug Resistance. 15, 3, p. 159-166 8 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Tetracycline resistome of the organic pig gut

Kazimierczak, K. A., Scott, K. P., Kelly, D. & Aminov, R. I., Mar 2009, In : Applied and Environmental Microbiology. 75, 6, p. 1717-1722 6 p.

Research output: Contribution to journalArticle

The Intestinal Microbiota of Irritable Bowel Syndrome Patients Is Characterized By Functional Dysbiosis

Chassard, C., Dapoigny, M. C., Scott, K. P., Del'Homme, C., Dubray, C., Eschalier, A., Flint, H. J., Bernalier-Donadille, A. & Flint, H. J., May 2009, In : Gastroenterology. 136, 5, Supplement 1, p. A214-A214 1 p.

Research output: Contribution to journalArticle

2008

A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones

Kazimierczak, K. A., Rincon, M. T., Patterson, A. J., Martin, J. C., Young, P., Flint, H. J. & Scott, K. P., Nov 2008, In : Antimicrobial Agents and Chemotherapy. 52, 11, p. 4001-4009 9 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Assessment of metabolic diversity within the intestinal microbiota from healthy humans using combined molecular and cultural approaches

Chassard, C., Scott, K. P., Marquet, P., Martin, J. C., Del'homme, C., Dapoigny, M., Flint, H. J. & Bernalier-Donadille, A., Dec 2008, In : FEMS Microbiology Ecology. 66, 3, p. 496-504 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Dietary fibre and the gut microbiota

Scott, K. P., Duncan, S. H. & Flint, H. J., Sep 2008, In : Nutrition Bulletin. 33, 3, p. 201-211 11 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

Transfer of conjugative elements from rumen and human Firmicutes bacteria to Roseburia inulinivorans

Scott, K. P., Martin, J. C., Mrazek, J. & Flint, H. J., Jun 2008, In : Applied and Environmental Microbiology. 74, 12, p. 3915-3917 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2007

Antibiotics and Resistance Genes: Influencing the Microbial Ecosystem in the Gut

Kazimierczak, K. A. & Scott, K. P., 2007, In : Advances in Applied Microbiology. 62, p. 269-292 24 p.

Research output: Contribution to journalLiterature review

12 Citations (Scopus)

Commensal bacteria in health and disease

Flint, H. J., Louis, P., Scott, K. P. & Duncan, S. H., Sep 2007, Virulence mechanisms of bacterial pathogens. Brogden, K. A., Minion, F. C., Cornick, N., Stanton, T. B., Zhang, Q., Nolan, L. K. & Wannemuehler, M. J. (eds.). 4 ed. ASM Press, p. 101-114 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection

Patterson, A. J., Colangeli, R., Spigaglia, P. & Scott, K. P., Mar 2007, In : Environmental Microbiology. 9, 3, p. 703-715 13 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
363 Citations (Scopus)