Keith Kerr

Research output

Research output per year 2004 2004 2010 2014 2018 2020 2023 2023

• 17 Article
• 2 Literature review
• 1 Abstract
• 1 Review article

Research output per year

Research output per year

Search results

• 2023

  Antibodies against endogenous retroviruses promote lung cancer immunotherapy

  TRACERx Consortium & CAPTURE Consortium, 20 Apr 2023, In: Nature. 616, 7957, p. 563-573 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tertiary Lymphoid Structures 100%
  • Endogenous Retroviruses 97%
  • Immunotherapy 62%
  • Lung Neoplasms 56%
  • Antibodies 39%
  52 Citations (Scopus)

• Evolutionary characterization of lung adenocarcinoma morphology in TRACERx

  TRACERx Consortium, 12 Apr 2023, In: Nature Medicine. 29, 4, p. 833-845 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Intrathoracic 100%
  • RNA Sequencing 81%
  • Adenocarcinoma of Lung 52%
  • Neoplasms 15%
  • Recurrence 6%
  19 Citations (Scopus)

• Lung adenocarcinoma promotion by air pollutants

  Hill, W., Lim, E. L., Weeden, C. E., Lee, C., Augustine, M., Chen, K., Kuan, F. C., Marongiu, F., Evans, E. J., Moore, D. A., Rodrigues, F. S., Pich, O., Bakker, B., Cha, H., Myers, R., van Maldegem, F., Boumelha, J., Veeriah, S., Rowan, A., Naceur-Lombardelli, C., & 54 othersKarasaki, T., Sivakumar, M., De, S., Caswell, D. R., Nagano, A., Black, J. R. M., Martínez-Ruiz, C., Ryu, M. H., Huff, R. D., Li, S., Favé, M. J., Magness, A., Suárez-Bonnet, A., Priestnall, S. L., Lüchtenborg, M., Lavelle, K., Pethick, J., Hardy, S., McRonald, F. E., Lin, M. H., Troccoli, C. I., Ghosh, M., Miller, Y. E., Merrick, D. T., Keith, R. L., Al Bakir, M., Bailey, C., Hill, M. S., Price, G., Kerr, K. M., TRACERx Consortium, Saal, L. S., Chen, Y., George, A. M., Abbosh, C., Kanu, N., Lee, S-H., McGranahan, N., Berg, C. D., Sasieni, P., Houlston, R., Turnbull, C., Lam, S., Awadalla, P., Grönroos, E., Downward, J., Jacks, T., Carlsen, C., Malanchi, I., Hackshaw, A., Litchfield, K., DeGregori, J., Jamal-Hanjani, M. & Swanton, C., 6 Apr 2023, In: Nature. 616, 7955, p. 159-167 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Air Pollutants 100%
  • Adenocarcinoma of Lung 81%
  • Lung Neoplasms 60%
  • Lung 32%
  • Smokers 25%
  118 Citations (Scopus)

• An endogenous inhibitor of angiogenesis downregulated by hypoxia in human aortic valve stenosis promotes disease pathogenesis

  Lewis, C. T. A., Mascall, K. S., Wilson, H. M., Murray, F., Kerr, K. M., Gibson, G., Buchan, K., Small, G. R. & Nixon, G. F., Jan 2023, In: Journal of Molecular and Cellular Cardiology. 174, p. 25-37 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Angiogenesis Inhibitors 100%
  • Aortic Valve Stenosis 91%
  • Aortic Valve 82%
  • Hypoxia 65%
  • Down-Regulation 58%
  2 Citations (Scopus)

  2 Downloads (Pure)
• 2022

  A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer

  Wu, Y., Biswas, D., Usaite, I., Angelova, M., Boeing, S., Karasaki, T., Veeriah, S., Czyzewska-Khan, J., Morton, C., Joseph, M., Hessey, S., Reading, J., Georgiou, A., Al-Bakir, M., Birkbak, N. J., Price, G., Khalil, M., Kerr, K., Richardson, S., Cheyne, H., & 36 othersCruickshank, T., Wilson, G. A., Rosenthal, R., Aerts, H., Hewish, M., Anand, G., Khan, S., Lau, K., Sheaff, M., Schmid, P., Lim, L., Conibear, J., Schwarz, R., Kaufmann, T. L., Huska, M., Shaw, J., Riley, J., Primrose, L., Fennell, D., Hackshaw, A., Ngai, Y., Sharp, A., Pressey, O., Smith, S., Gower, N., Dhanda, H. K., Chan, K., Chakraborty, S., Litchfield, K., Thakkar, K., TRACERx Consortium, McGranahan, N., Jamal-Hanjani, M., Quezada, S., Hayday, A. C. & Swanton, C., Jun 2022, In: Nature Cancer. 3, 6, p. 696-709 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Non-Small Cell Lung Carcinoma 100%
  • T-Lymphocytes 69%
  • Survival 61%
  • Population 43%
  • Memory 34%
  39 Citations (Scopus)
• 2021

  The evolving landscape of biomarker testing for non-small cell lung cancer in Europe

  Kerr, K., Bibeau, F., Thunnissen, E., Botling, J., Ryška, A., Wolf, J., Öhrling, K., Burdon, P., Malapelle, U. & Büttner, R., 1 Dec 2021, In: Lung Cancer. 154, p. 161-175 15 p.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • Non-Small Cell Lung Carcinoma 100%
  • Biomarkers 72%
  • Mutation 31%
  • Technology 21%
  • High-Throughput Nucleotide Sequencing 21%
  106 Citations (Scopus)

  12 Downloads (Pure)
• 2020

  Hypoxia PET/CT and Colorectal Cancer: A Case Report

  Laws, K., Murray, G. I., Kerr, K., McKiddie, F., Dall'angelo, S., Zanda, M., Fleming, I. & Samuel, L., 12 Aug 2020, In: Journal of Case Reports and Images in Oncology. 1(1), 2-5, 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Positron Emission Tomography Computed Tomography 100%
  • Colorectal Neoplasms 72%
  • Hypoxia 72%
  • fluoroazomycin arabinoside 50%
  • Carbonic Anhydrase IX 39%
  4 Downloads (Pure)

• Cytology for PD-L1 testing: A systematic review

  Gosney, J. R., Boothman, A-M., Ratcliffe, M. & Kerr, K. M., 1 Mar 2020, In: Lung Cancer. 141, p. 101-106 6 p.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • Cell Biology 100%
  • Systematic Reviews 84%
  • Ligands 81%
  • Apoptosis 70%
  • Histology 50%
  40 Citations (Scopus)

  10 Downloads (Pure)
• 2018

  Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy

  Wilson, H. M., Cheyne, L., Brown, P. A. J., Kerr, K., Hannah, A., Srinivasan, J., Duniak, N., Horgan, G. & Dawson, D. K., 31 Dec 2018, In: JACC: Basic to Translational Science. 3, 6, p. 766-778 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Takotsubo Cardiomyopathy 100%
  • Theoretical Models 59%
  • Myocardium 30%
  • Neutrophils 28%
  • Heart Failure 26%
  81 Citations (Scopus)

  12 Downloads (Pure)

• Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer

  Bonomi, P. D., Gandara, D., Hirsch, F. R., Kerr, K. M., Obasaju, C., Paz-Ares, L., Bellomo, C., Bradley, J. D., Bunn, P. A., Culligan, M., Jett, J. R., Kim, E. S., Langer, C. J., Natale, R. B., Novello, S., Pérol, M., Ramalingam, S. S., Reck, M., Reynolds, C. H., Smit, E. F., & 5 othersSocinski, M. A., Spigel, D. R., Vansteenkiste, J. F., Wakelee, H. & Thatcher, N., 1 Aug 2018, In: Annals of Oncology. 29, 8, p. 1701-1709 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Squamous Cell Neoplasms 100%
  • ErbB Receptors 76%
  • Lung Neoplasms 63%
  • Monoclonal Antibodies 58%
  • Biomarkers 52%
  23 Citations (Scopus)

  12 Downloads (Pure)
• 2014

  2nd ESMO consensus conference on lung cancer: Early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up

  Vansteenkiste, J., Crinò, L., Dooms, C., Douillard, J. Y., Faivre-Finn, C., Lim, E., Rocco, G., Senan, S., van Schil, P., Veronesi, G., Stahel, R., Peters, S., Felip, E., Kerr, K., Besse, B., Eberhardt, W., Edelman, M., Mok, T., O'Byrne, K., Novello, S., & 15 othersBubendorf, L., Marchetti, A., Baas, P., Reck, M., Syrigos, K., Paz-Ares, L., Smit, E. F., Meldgaard, P., Adjei, A., Nicolson, M., Weder, W., de Ruysscher, D., Le Pechoux, C., de Leyn, P. & Westeel, V., 1 Aug 2014, In: Annals of Oncology. 25, 8, p. 1462-1474 13 p., mdu089.

  Research output: Contribution to journal › Article › peer-review

  • Congresses 100%
  • Non-Small Cell Lung Carcinoma 90%
  • Lung Neoplasms 80%
  • Molecular Pathology 28%
  • Therapeutics 16%
  388 Citations (Scopus)

• 2nd ESMO Consensus Conference on Lung Cancer: Non-small-cell lung cancer first-line/second and further lines in advanced disease

  Besse, B., Adjei, A., Baas, P., Meldgaard, P., Nicolson, M., Paz-Ares, L., Reck, M., Smit, E. F., Syrigos, K., Stahel, R., Felip, E., Peters, S., Stahel, R., Felip, E., Peters, S., Kerr, K., Besse, B., Vansteenkiste, J., Eberhardt, W., Edelman, M., & 27 othersMok, T., O'Byrne, K., Novello, S., Bubendorf, L., Marchetti, A., Baas, P., Reck, M., Syrigos, K., Paz-Ares, L., Smit, E. F., Meldgaard, P., Adjei, A., Nicolson, M., Crinò, L., Van Schil, P., Senan, S., Faivre-Finn, C., Rocco, G., Veronesi, G., Douillard, J. Y., Lim, E., Dooms, C., Weder, W., De Ruysscher, D., Le Pechoux, C., De Leyn, P. & Westeel, V., 1 Aug 2014, In: Annals of Oncology. 25, 8, p. 1475-1484 10 p., mdu123.

  Research output: Contribution to journal › Article › peer-review

  • Non-Small Cell Lung Carcinoma 100%
  • Lung Neoplasms 88%
  • Molecular Pathology 31%
  • Congresses 27%
  • Biomarkers 18%
  208 Citations (Scopus)

• Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study

  Jamal-Hanjani, M., Hackshaw, A., Ngai, Y., Shaw, J., Dive, C., Quezada, S., Middleton, G., de Bruin, E., Le Quesne, J., Shafi, S., Falzon, M., Horswell, S., Blackhall, F., Khan, I., Janes, S., Nicolson, M., Lawrence, D., Forster, M., Fennell, D., Lee, S. M., & 51 othersLester, J., Kerr, K., Muller, S., Iles, N., Smith, S., Murugaesu, N., Mitter, R., Salm, M., Stuart, A., Matthews, N., Adams, H., Ahmad, T., Attanoos, R., Bennett, J., Birkbak, N. J., Booton, R., Brady, G., Buchan, K., Capitano, A., Chetty, M., Cobbold, M., Crosbie, P., Davies, H., Denison, A., Djearman, M., Goldman, J., Haswell, T., Joseph, L., Kornaszewska, M., Krebs, M., Langman, G., MacKenzie, M., Millar, J., Morgan, B., Naidu, B., Nonaka, D., Peggs, K., Pritchard, C., Remmen, H., Rowan, A., Shah, R., Smith, E., Summers, Y., Taylor, M., Veeriah, S., Waller, D., Wilcox, B., Wilcox, M., Woolhouse, I., McGranahan, N. & Swanton, C., 8 Jul 2014, In: PLoS Biology. 12, 7, p. 1-7 7 p., e1001906.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • precision medicine 100%
  • Precision Medicine 66%
  • lung neoplasms 64%
  • Heterogeneity 56%
  • lungs 48%
  163 Citations (Scopus)

  8 Downloads (Pure)
• 2013

  Serpin b3 is associated with poor survival after chemotherapy and is a potential novel predictive biomarker in advanced non-small-cell lung cancer

  Urquhart, G., Kerr, K. M., Nicolson, M., Loo, P. S., Sharma, R., Shrimali, R. & Petty, R. D., Dec 2013, In: Journal of Thoracic Oncology. 8, 12, p. 1502-1509 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Serpins 100%
  • Non-Small Cell Lung Carcinoma 63%
  • Biomarkers 46%
  • Drug Therapy 41%
  • Survival 39%
  8 Citations (Scopus)
• 2010

  MAGEA tumour antigens mediate platinum cytotoxicity in NSCLC

  Collie-Duguid, E. S. R., Bissett, J. D., Petty, R. D., Nicolson, M. C. & Kerr, K., Nov 2010, In: European Journal of Cancer. 8, 7, p. 99-100 2 p.

  Research output: Contribution to journal › Abstract › peer-review

• Squamous cell carcinoma of an ileo-anal pouch

  Macdonald, E., Gee, C., Kerr, K., Denison, A., Keenan, R. & Binnie, N., Sept 2010, In: Colorectal Disease. 12, 9, p. 945-946 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• How to investigate a patient with suspected interstitial lung disease

  Dempsey, O. J., Kerr, K. M., Remmen, H. & Denison, A. R., 2010, In: BMJ. 340, c2843.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)
• 2008

  Cutaneous penile and perianal Crohn's disease treated with a combination of medical and surgical interventions

  Rajpara, S., Siddha, S. K., Ormerod, A., Kerr, K. & Kolhe, P. S., 1 Feb 2008, In: The Australasian Journal of Dermatology. 49, 1, p. 21-24 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Crohn Disease 100%
  • Clobetasol 80%
  • Minocycline 65%
  • Thalidomide 65%
  • Skin Transplantation 65%
  15 Citations (Scopus)
• 2006

  Tumor transcriptome reveals the predictive and prognostic impact of lysosomal protease inhibitors in non-small-cell lung cancer

  Petty, R. D., Kerr, K., Murray, G. I., Nicolson, M., Rooney, P. H., Bissett, D. & Collie-Duguid, E. S. R., 10 Apr 2006, In: Journal of Clinical Oncology. 24, 11, p. 1729-1744 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Protease Inhibitors 100%
  • Transcriptome 88%
  • Non-Small Cell Lung Carcinoma 86%
  • Platinum 84%
  • Drug Therapy 56%
  47 Citations (Scopus)
• 2004

  Severe breathlessness, mouth ulcers and skin blistering in a female

  Gudi, V., Ormerod, A., Weir, J., Kerr, K. & Devereux, G. S., 1 Nov 2004, In: European Respiratory Journal. 24, 5, p. 884-887 4 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application

  Petty, R. D., Nicolson, M. C., Kerr, K. M., Collie-Duguid, E. & Murray, G. I., 15 May 2004, In: Clinical Cancer Research. 10, 10, p. 3237-3248 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Expression Profiling 100%
  • Non-Small Cell Lung Carcinoma 86%
  • Oligonucleotide Array Sequence Analysis 28%
  • Premature Mortality 16%
  • Molecular Biology 11%
  127 Citations (Scopus)