No photo of Laurent Trembleau

Laurent Trembleau

Dr

    • 1109 Citations
    20002020

    Research output per year

    If you made any changes in Pure these will be visible here soon.

    Research Output

    Filter
    Article
    2020

    Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide

    Idress, M., Milne, B. F., Thompson, G. S., Trembleau, L., Jaspars, M. & Houssen, W. E., 19 Feb 2020, In : Molecules. 25, 4, 922.

    Research output: Contribution to journalArticle

    Open Access
    File
    2019

    Enzymatic Reconstitution and Biosynthetic Investigation of the Bacterial Carbazole Neocarazostatin A

    Liu, Y., Su, L., Fang, Q., Tabudravu, J., Yang, X., Rickaby, K., Trembleau, L., Kyeremeh, K., Deng, Z., Deng, H. & Yu, Y., 20 Dec 2019, In : Journal of Organic Chemistry. 84, 24, p. 16323-16328 6 p.

    Research output: Contribution to journalArticle

    Open Access
    1 Citation (Scopus)
    2018

    Physicochemical Tools: Toward a Detailed Understanding of the Architecture of Targeted Radiotherapy Nanoparticles

    Cabello, G., Nwoko, K. C., Mingarelli, M., McLaughlin, A. C., Trembleau, L., Feldmann, J., Cuesta Ciscar, A. & Smith, T. A. D., 2018, In : ACS Applied Bio Materials. 1, 5, p. 1639-1646 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    3 Citations (Scopus)
    2017

    A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

    Booth, J., Alexandru-Crivac, C-N., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E. & Shalashilin, D. V., 18 May 2017, In : The Journal of Physical Chemistry Letters. 8, 10, p. 2310-2315 6 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    4 Citations (Scopus)
    10 Downloads (Pure)

    Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

    Alexandru-Crivac, C. N., Umeobika, C., Leikoski, N., Jokela, J., Rickaby, K., Grilo, A. M., Sjo, P., Plowright, A. T., Idress, M., Siebs, E., Nneoyi-Egbe, A., Wahlsten, M., Sivonen, K., Jaspars, M., Trembleau, L., Fewer, D. P. & Houssen Ibrahim, W. E., 4 Oct 2017, In : Chemical Communications. 53, 77, p. 10656-10659 4 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    4 Citations (Scopus)
    10 Downloads (Pure)
    2016

    A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

    Parajuli, A., Kwak, D. H., Dalponte, L., Leikoski, N., Galica, T., Umeobika, U., Trembleau, L., Bent, A., Sivonen, K., Wahlsten, M., Wang, H., Rizzi, E., De Bellis, G., Naismith, J., Jaspars, M., Liu, X., Houssen, W. & Fewer, D. P., 7 Mar 2016, In : Angewandte Chemie. 128, 11, p. 3660-3663 4 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    17 Citations (Scopus)
    8 Downloads (Pure)
    3 Citations (Scopus)
    8 Downloads (Pure)

    Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators

    Greig, I. R., Baillie, G. L., Abdelrahman, M., Trembleau, L. & Ross, R. A., 15 Sep 2016, In : Bioorganic & Medicinal Chemistry Letters. 26, 18, p. 4403-4407 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    9 Citations (Scopus)
    6 Downloads (Pure)

    Different N—H···π interactions in two indole derivatives

    Kerr, J. R., Trembleau, L., Storey, J. M. D., Wardell, J. L. & Harrison, W. T. A., May 2016, In : Acta Crystallographica Section E: Crystallographic Communications. 72, 5, p. 699-703 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    2 Citations (Scopus)
    4 Downloads (Pure)
    Open Access
    File
    1 Citation (Scopus)
    4 Downloads (Pure)
    2015
    Open Access
    File
    4 Citations (Scopus)
    9 Downloads (Pure)

    Discovery of a single monooxygenase catalyzing the carbamate formation and ring contraction in the biosynthesis of legonmycins

    Huang, S., Tabudravu, J., Elsayed, S. S., Travert, J., Peace, D., Tong, M. H., Kyeremeh, K., Kelly, S., Trembleau, L. A. C., Ebel, R. P., Jaspars, M., Yu, Y. & Deng, H., 19 Oct 2015, In : Angewandte Chemie International Edition. 54, 43, p. 12697-12701 4 p.

    Research output: Contribution to journalArticle

    17 Citations (Scopus)
    6 Downloads (Pure)
    2014

    In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569

    Gamage, T. F., Ignatowska-Jankowska, B. M., Wiley, J. L., Abdelrahman, M., Trembleau, L., Greig, I. R., Thakur, G. A., Tichkule, R., Poklis, J., Ross, R. A., Pertwee, R. G. & Lichtman, A. H., Apr 2014, In : Behavioural Pharmacology. 25, 2, p. 182-185 4 p.

    Research output: Contribution to journalArticle

    40 Citations (Scopus)

    Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria

    Tadesse, M., Svenson, J., Sepicic, K., Trembleau, L., Engqvist, M., Andersen, J. H., Jaspars, M., Stensvag, K. & Haug, T., 28 Feb 2014, In : Journal of Natural Products. 77, 2, p. 364-369 6 p.

    Research output: Contribution to journalArticle

    20 Citations (Scopus)
    2013

    Receptor conformational change induces fluoride binding despite competitive water binding

    Trembleau, L., Smith, T. A. D. & Abdelrahman, M. H., 4 Jul 2013, In : Chemical Communications. 49, 52, p. 5850-5852 3 p.

    Research output: Contribution to journalArticle

    18 Citations (Scopus)
    2012

    The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

    Houssen, W. E., Koehnke, J., Bent, A., Zollman, D., Morawitz, F., Shirran, S., Vendome, J., Nneoyiegbe, A. F., Trembleau, L., Botting, C. H., Smith, M. C. M., Jaspars, M. & Naismith, J. H., Aug 2012, In : Nature Structural & Molecular Biology. 19, 8, p. 767-772 6 p.

    Research output: Contribution to journalArticle

    87 Citations (Scopus)
    2011
    File
    7 Citations (Scopus)
    Open Access
    File
    11 Citations (Scopus)
    3 Downloads (Pure)

    Development of 18F-fluorinatable dendrons and their application to cancer cell targeting

    Trembleau, L., Simpson, M., Cheyne, R. W., Escofet, I., Appleyard, M. V. C. L., Murray, K., Sharp, S., Thompson, A. M. & Smith, T. A. D., Nov 2011, In : New Journal of Chemistry. 35, 11, p. 2496-2502 7 p.

    Research output: Contribution to journalArticle

    14 Citations (Scopus)
    Open Access
    File
    10 Citations (Scopus)
    4 Downloads (Pure)

    Synthesis and characterisation of biologically compatible TiO2 nanoparticles

    Cheyne, R. W., Smith, T. A. D., Trembleau, L. A. C. & McLaughlin, A., 2011, In : Nanoscale Research Letters. 6, -, 423.

    Research output: Contribution to journalArticle

    Open Access
    File
    25 Citations (Scopus)
    4 Downloads (Pure)
    2010

    Multigram-scale synthesis of short peptides via a simplified repetitive solution-phase procedure

    Meneses, C., Nicoll, S. L. & Trembleau, L. A. C., 2010, In : Journal of Organic Chemistry. 75, 3, p. 564-569 6 p.

    Research output: Contribution to journalArticle

    9 Citations (Scopus)
    2007

    5-chloro-3-ethyl-N-[2-(morpholin-4-yl)ethyl]-1H-indole-2-carboxamide

    Muirhead, K. E. A., Trembleau, L. & Harrison, W. T. A., 1 Aug 2007, In : Acta Crystallographica Section E: Structure Reports Online. 63, 8, 11 p., o3389.

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    5-Chloro-3-ethyl-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide

    Muirhead, K. E. A., Trembleau, L. & Harrison, W. T. A., Aug 2007, In : Acta Crystallographica Section E: Structure Reports Online. 63, 8, 11 p., o3390.

    Research output: Contribution to journalArticle

    1 Citation (Scopus)
    2006

    Lipid fluorination enables phase separation from fluid phospholipid bilayers

    Webb, S. J., Greenway, K., Bayati, M. & Trembleau, L. A. C., May 2006, In : Organic & Biomolecular Chemistry. 4, p. 2399-2407 8 p.

    Research output: Contribution to journalArticle

    19 Citations (Scopus)
    2005

    Membrane Composition Determines the Fate of Aggregated Vesicles

    Webb, S. J., Wang, X., Mart, R. J. & Trembleau, L. A. C., 2005, In : Organic & Biomolecular Chemistry. 3, p. 3615-3617 2 p.

    Research output: Contribution to journalArticle

    20 Citations (Scopus)
    2004

    Galmic, a nonpeptide galanin receptor agonist, affects behaviours in seizure, pain, and forced-swim tests

    Barfai, T., lu, X., Badie-Mahdavi, H., Barr, A. M., Mazarati, A., Hua, X. Y., Yaksh, T., Haberhauser, G., Ceide, S. C., Trembleau, L. A. C., Somogyi, L., Krock, L. & Rebek Jnr, J., 2004, In : PNAS. 101, p. 10470-10475 5 p.

    Research output: Contribution to journalArticle

    110 Citations (Scopus)

    Helical Folding of Alkanes in a Self-Assembled, Cylindrical Capsule

    Scarso, A., Trembleau, L. A. C. & Rebek Jnr, J., 2004, In : Journal of the American Chemical Society. 126, p. 13512-13518 6 p.

    Research output: Contribution to journalArticle

    127 Citations (Scopus)

    Interactions Between a Surfactant and Cavitand: Blur Distinctions Between Host and Guest

    Trembleau, L. A. C. & Rebek Jnr, J., 2004, In : Chemical Communications. 1, p. 58-59 1 p.

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    Kinetically Stable Complexes in Water: The Role of Hydration and Hydrophobicity

    Biros, S. M., Ullrich, E. C., Hof, F., Trembleau, L. A. C. & Rebek Jnr, J., 2004, In : Journal of the American Chemical Society. 126, p. 2870-2876 6 p.

    Research output: Contribution to journalArticle

    93 Citations (Scopus)

    Synthesis of galmic: A nonpeptide galanin receptor agonist

    Ceide, S. C., Trembleau, L. A. C., Haberhauer, G., Somogyi, L., Bartfai, T. & Rebek Jnr, J., 2004, In : PNAS. 101, 48, p. 16727-16732 5 p.

    Research output: Contribution to journalArticle

    25 Citations (Scopus)
    2003

    Acetylcholine Recognition by a Deep, Biomimetic Pocket

    Hof, F., Trembleau, L. A. C., Ulrich, E. & Rebek Jnr, J., 2003, In : Angewandte Chemie International Edition. 42, p. 3150-3153 3 p.

    Research output: Contribution to journalArticle

    89 Citations (Scopus)

    Encapsulation Induces Helical Folding of Alkanes

    Scarso, A., Trembleau, L. A. C. & Rebek Jnr, J., 2003, In : Angewandte Chemie International Edition. 42, p. 5499-5502 3 p.

    Research output: Contribution to journalArticle

    95 Citations (Scopus)

    Helical Conformation of Alkanes in a Hydrophobic Cavitand

    Trembleau, L. A. C. & Rebek Jnr, J., 2003, In : Science. 301, p. 1219-1220 1 p.

    Research output: Contribution to journalArticle

    167 Citations (Scopus)
    2000
    1 Citation (Scopus)
    22 Citations (Scopus)