• 811 Citations
20052019
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Research Output 2005 2019

  • 811 Citations
  • 19 Article
2019

Dependence on Dectin-1 Varies With Multiple Candida Species

Thompson, A., Griffiths, J. S., Walker, L., da Fonseca, D. M., Lee, K. K., Taylor, P. R., Gow, N. A. R. & Orr, S. J., 6 Aug 2019, In : Frontiers in Microbiology. 10, 12 p., 1800.

Research output: Contribution to journalArticle

Open Access
File
Candida
C-Type Lectins
Infection
dectin 1
Immunity
2018
6 Citations (Scopus)
8 Downloads (Pure)

Cell walls of the dimorphic fungal pathogens Sporothrix schenckii and Sporothrix brasiliensis exhibit bilaminate structures and sloughing of extensive and intact layers

Lopes Bezerra, L. M., Walker, L. A., Vega, G. N., MoraMontes, H. M., Neves, G. W. P., Villalobos-Duno, H., Barreto, L., Garcia, K., Franco, B., Martínez-Álvarez, J. A., Munro, C. A. & Gow, N. A. R., 9 Mar 2018, In : PLoS Neglected Tropical Diseases. 12, 3, e0006169.

Research output: Contribution to journalArticle

Open Access
File
Sporothrix
Cell Wall
Sporotrichosis
Fungi
Glycogen
4 Citations (Scopus)
4 Downloads (Pure)

Generating genomic platforms to study Candida albicans pathogenesis

Legrand, M., Bachellier-Bassi, S., Lee, K. K., Chaudhari, Y., Tournu, H., Arbogast, L., Boyer, H., Chauvel, M., Cabral, V., Maufrais, C., Nesseir, A., Maslanka, I., Permal, E., Rossignol, T., Walker, L. A., Zeidler, U., Znaidi, S., Schoeters, F., Majgier, C., Julien, R. A. & 6 others, Ma, L., Tichit, M., Bouchier, C., Dijck, P. V., Munro, C. A. & d'Enfert, C., 21 Aug 2018, In : Nucleic Acids Research. 46, 14, p. 6935-6949 14 p.

Research output: Contribution to journalArticle

Open Access
File
Candida albicans
Open Reading Frames
Virulence
Proteins
Yeasts
4 Downloads (Pure)

Mitogen activated kinases (MAPK) and protein phosphatases are involved in Aspergillus fumigatus adhesion and biofilm formation

Manfiolli, A., Dos Reis, T. F., de Assis, L. J., de Castro, P. A., Pereira Silva, L., Hori, J., Walker, L. A., Munro, C. A., Rajendran, R., Ramage, G. & Goldman, G. H., Mar 2018, In : The Cell Surface. 1, p. 43-56 14 p.

Research output: Contribution to journalArticle

Open Access
File
Mitogen-Activated Protein Kinase Phosphatases
Aspergillus fumigatus
Biofilms
Mitogen-Activated Protein Kinases
Extracellular Matrix
4 Citations (Scopus)
5 Downloads (Pure)

The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris

Junker, K., Bravo Ruiz, G., Lorenz, A., Walker, L., Gow, N. & Wendland, J., 8 Oct 2018, In : Scientific Reports. 8, 5 p., 14959.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycopsis
Prednisolone
Candida
Yeasts
Pharmaceutical Preparations
11 Citations (Scopus)
3 Downloads (Pure)

The type VI secretion system deploys antifungal effectors against microbial competitors

Trunk, K., Peltier, J., Liu, Y-C., Dill, B. D., Walker, L., Gow, N. A. R., Stark, M. J. R., Quinn, J., Strahl, H., Trost, M. & Coulthurst, S. J., 1 Aug 2018, In : Nature Microbiology. 3, 8, p. 920-931 12 p.

Research output: Contribution to journalArticle

Open Access
File
Serratia marcescens
Cell Shape
Poisons
Autophagy
Eukaryotic Cells
20 Citations (Scopus)
6 Downloads (Pure)

The Viscoelastic Properties of the Fungal Cell Wall Allow Traffic of AmBisome as Intact Liposome Vesicles

Walker, L., Sood, P., Lenardon, M., Milne, G., Olson, J., Jensen, G., Wolf, J., Casadevall, A., Adler-Moore, J. & Gow, N. A. R., 6 Feb 2018, In : mBio. 9, 1, e02383-17.

Research output: Contribution to journalArticle

Open Access
File
Liposomes
Cell Wall
Amphotericin B
Candida albicans
Ergosterol
2017
16 Downloads (Pure)

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining

Nogueira, MF., Istel, F., Jenull, S., Walker, L. A., Gow, N. & Lion, T., 31 Dec 2017, In : Journal of Microbiology and Modern Techniques. 2, 1, 9 p., 101.

Research output: Contribution to journalArticle

Open Access
File
Cellular Structures
Candida
Cell Wall
caspofungin
Fluorescence
2016
40 Citations (Scopus)
10 Downloads (Pure)

Lactate signalling regulates fungal β-glucan masking and immune evasion

Ballou, E., M. Avelar, G., Childers, D. S., Mackie, J., Bain, J. M., Wagener, J., Kastora, S. L., Panea, M. D., Hardison, S. E., Walker, L., Erwig, L. P., Munro, C. A., Gow, N. A. R., Brown, G. D., MacCallum, D. M. & Brown, A. J. P., 12 Dec 2016, In : Nature Microbiology. 2, 16238.

Research output: Contribution to journalArticle

Open Access
File
Immune Evasion
Glucans
Candida albicans
Lactic Acid
Fungi
2015
19 Citations (Scopus)

Aspergillus fumigatus sitA phosphatase homologue is important for adhesion, cell wall integrity, biofilm formation and virulence

Bom, V. L. P., de Castro, P. A., Winkelströter, L. K., Marine, M., Hori, J. I., Ramalho, L. N. Z., Dos Reis, T. F., Goldman, M. H. S., Brown, N. A., Rajendran, R., Ramage, G., Walker, L. A., Munro, C. A., Rocha, M. C., Malavazi, I., Hagiwara, D. & Goldman, G. H., Aug 2015, In : Eukaryotic Cell. 14, 8, p. 728-744 17 p.

Research output: Contribution to journalArticle

Aspergillus fumigatus
Biofilms
Phosphoric Monoester Hydrolases
Cell Wall
Virulence
32 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
caspofungin
Chitin
Aspergillus fumigatus
Up-Regulation
Chitin Synthase
52 Citations (Scopus)
4 Downloads (Pure)

Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance

Ene, I. V., Walker, L. A., Schiavone, M., Lee, K. K., Martin-Yken, H., Dague, E., Gow, N. AR., Munro, C. A. & Brown, A. JP., 2015, In : mBio. 6, 4, e00986-15.

Research output: Contribution to journalArticle

Open Access
File
Osmotic Pressure
Elasticity
Cell Wall
Enzymes
Shock
2013
19 Citations (Scopus)
5 Downloads (Pure)

Cell wall stress induces alternative fungal cytokinesis and septation strategies

Walker, L., Lenardon, M. D., Preechasuth, K., Munro, C. A. & Gow, N. A. R., 15 Jun 2013, In : Journal of Cell Science. 126, 12, p. 2668-2677 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cytokinesis
Chitin Synthase
Cell Division
Cell Wall
Chitin
79 Citations (Scopus)
5 Downloads (Pure)
Open Access
File
caspofungin
Chitin
Candida
Echinocandins
Candida albicans
57 Citations (Scopus)
4 Downloads (Pure)

Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis

Gioti, A., Nystedt, B., Li, W., Xu, J., Andersson, A., Averette, A. F., Münch, K., Wang, X., Kappauf, C., Kingsbury, J. M., Kraak, B., Walker, L., Johansson, H. J., Holm, T., Lehtiö, J., Stajich, J. E., Mieczkowski, P., Kahmann, R., Kennell, J. C., Cardenas, M. E. & 9 others, Lundeberg, J., Saunders, C. W., Boekhout, T., Dawson, T. L., Munro, C. A., de Groot, P. W. J., Butler, G., Heitman, J. & Scheynius, A., 22 Jan 2013, In : mBio. 4, 1, 16 p., e00572-12.

Research output: Contribution to journalArticle

Open Access
File
Malassezia
Atopic Dermatitis
Dandruff
Yeasts
Skin
2012
55 Citations (Scopus)
4 Downloads (Pure)

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

Leach, M., Budge, S., Walker, L., Munro, C., Cowen, L. E. & Brown, A. J. P., 27 Dec 2012, In : PLoS Pathogens. 8, 12, 20 p., e1003069.

Research output: Contribution to journalArticle

Open Access
File
HSP90 Heat-Shock Proteins
Cell Wall
Yeasts
Candida albicans
Heat-Shock Response
2008
203 Citations (Scopus)
10 Downloads (Pure)

Stimulation of chitin synthesis rescues Candida albicans from echinocandins

Walker, L., Munro, C. A., De Bruijn, I., Lenardon, M. D., McKinnon, A. D. & Gow, N. A. R., 8 Apr 2008, In : PLoS Pathogens. 4, 4, 12 p., e1000040.

Research output: Contribution to journalArticle

Open Access
File
2007
168 Citations (Scopus)
4 Downloads (Pure)

The PKC, HOG and Ca2+ signalling pathways co-ordinately regulate chitin synthesis in Candida albicans

Munro, C. A., Selvaggini, S., de Bruijn, I., Walker, L., Lenardon, M. D., Gerssen, B., Milne, S., Brown, A. J. P. & Gow, N. A. R., Mar 2007, In : Molecular Microbiology. 63, 5, p. 1399-1413 15 p.

Research output: Contribution to journalArticle

Open Access
File
2005
42 Citations (Scopus)

Global regulation of the protein kinase Gcn2 in the human pathogen Candida albicans

Tournu, H., Tripathi, G., Bertram, G., MacAskill, S., Mavor, A., Walker, L., Odds, F. C., Gow, N. A. R. & Brown, A. J. P., 2005, In : Eukaryotic Cell. 4, 10, p. 1687-1696 9 p.

Research output: Contribution to journalArticle