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Research Output

  • 1887 Citations
  • 30 Article
2020

Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 30 Jul 2020, In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

2018

Structural basis of the filamin A actin-binding domain interaction with F-actin

Iwamoto, D. V., Huehn, A., Simon, B., Huet-Calderwood, C., Baldassarre, M., Sindelar, C. V. & Calderwood, D. A., 17 Sep 2018, In : Nature Structural & Molecular Biology. 25, p. 918-927 10 p.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
6 Downloads (Pure)
2016

Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms

Shi, X., Mihaylova, V. T., Kuruvilla, L., Chen, F., Viviano, S., Baldassarre, M., Sperandio, D., Martinez, R., Yue, P., Bates, J. G., Breckenridge, D. G., Schlessinger, J., Turk, B. E. & Calderwood, D. A., 2 Aug 2016, In : PNAS. 113, 31, p. E4558-4566 9 p.

Research output: Contribution to journalArticle

Open Access
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27 Citations (Scopus)
10 Downloads (Pure)

NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting

Graziadio, A., Zanda, M., Frau, S., Fleming, I. N., Musolino, M., Dall'Angelo, S., Baldassarre, M. & Piras, M., 18 May 2016, In : Bioconjugate Chemistry. 27, 5, p. 1332-1340 9 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
7 Downloads (Pure)

Novel Synthetic Strategies for the Development of Tryptophan-Proline Chimeras, Useful Tool for Drug Discovery

De Filippis, B., Fantacuzzi, M., Piras, M. & Baldassarre, M., 1 Sep 2016, In : Current Bioactive Compounds. 12, 3, p. 161-167 7 p.

Research output: Contribution to journalArticle

Open Access
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7 Downloads (Pure)
2013
9 Citations (Scopus)
2012

Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells

Baldassarre, M., Razinia, Z., Brahme, N. N., Buccione, R. & Calderwood, D. A., 15 Aug 2012, In : Journal of Cell Science. 125, 16, p. 3858-3869 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Polarised apical-like intracellular sorting and trafficking regulates invadopodia formation and degradation of the extracellular matrix in cancer cells

Caldieri, G., Capestrano, M., Bicanova, K., Beznoussenko, G., Baldassarre, M. & Buccione, R., Nov 2012, In : European Journal of Cell Biology. 91, 11-12, p. 961-968 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Functional and Structural Insights into ASB2α, a Novel Regulator of Integrin-dependent Adhesion of Hematopoietic Cells

Lamsoul, I., Burande, C. F., Razinia, Z., Houles, T. C., Menoret, D., Baldassarre, M., Erard, M., Moog-Lutz, C., Calderwood, D. A. & Lutz, P. G., 2 Sep 2011, In : The Journal of Biological Chemistry. 286, 35, p. 30571-30581 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain

Razinia, Z., Baldassarre, M., Bouaouina, M., Lamsoul, I., Lutz, P. G. & Calderwood, D. A., 1 Aug 2011, In : Journal of Cell Science. 124, 15, p. 2631-2641 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2009

Filamin A–β1 integrin complex tunes epithelial cell response to matrix tension

Gehler, S., Baldassarre, M., Lad, Y., Leight, J. L., Wozniak, M. A., Riching, K. M., Eliceiri, K. W., Weaver, V. M., Calderwood, D. A. & Keely, P. J., 15 Jul 2009, In : Molecular Biology of the Cell. 20, 14, p. 3224-3238 15 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)

Filamins regulate cell spreading and initiation of cell migration

Baldassarre, M., Razinia, Z., Burande, C. F., Lamsoul, I., Lutz, P. G. & Calderwood, D. A., 2009, In : PloS ONE. 4, 11, e7830.

Research output: Contribution to journalArticle

Open Access
File
73 Citations (Scopus)
7 Downloads (Pure)
2008

ASB2 targets filamins A and B to proteasomal degradation

Heuzé, M. L., Lamsoul, I., Baldassarre, M., Lad, Y., Lévêque, S., Razinia, Z., Moog-Lutz, C., Calderwood, D. A. & Lutz, P. G., 15 Dec 2008, In : Blood. 112, 13, p. 5130-5140 11 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation

Ayala, I., Baldassarre, M., Giacchetti, G., Caldieri, G., Tetè, S., Luini, A. & Buccione, R., 1 Feb 2008, In : Journal of Cell Science. 121, 3, p. 369-378 10 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)
2006

Actin dynamics at sites of extracellular matrix degradation

Baldassarre, M., Ayala, I., Beznoussenko, G., Giacchetti, G., Machesky, L. M., Luini, A. & Buccione, R., Dec 2006, In : European Journal of Cell Biology. 85, 12, p. 1217-1231 15 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Invadopodia: a guided tour

Ayala, I., Baldassarre, M., Caldieri, G. & Buccione, R., Apr 2006, In : European Journal of Cell Biology. 85, 3-4, p. 159-64 6 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Mancozeb exposure in vivo impairs mouse oocyte fertilizability

Rossi, G., Buccione, R., Baldassarre, M., Macchiarelli, G., Palmerini, M. G. & Cecconi, S., Feb 2006, In : Reproductive Toxicology. 21, 2, p. 216-219 4 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

The molecular basis of filamin binding to integrins and competition with talin

Kiema, T., Lad, Y., Jiang, P., Oxley, C. L., Baldassarre, M., Wegener, K. L., Campbell, I. D., Ylänne, J. & Calderwood, D. A., 3 Feb 2006, In : Molecular Cell. 21, 3, p. 337-47 11 p.

Research output: Contribution to journalArticle

279 Citations (Scopus)
2005

Glycerophosphoinositols inhibit the ability of tumour cells to invade the extracellular matrix

Buccione, R., Baldassarre, M., Trapani, V., Catalano, C., Pompeo, A., Brancaccio, A., Giavazzi, R., Luini, A. & Corda, D., Feb 2005, In : European Journal of Cancer. 41, 3, p. 470-6 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2004

Intracellular processing and activation of membrane type 1 matrix metalloprotease depends on its partitioning into lipid domains

Mazzone, M., Baldassarre, M., Beznoussenko, G., Giacchetti, G., Cao, J., Zucker, S., Luini, A. & Buccione, R., 15 Dec 2004, In : Journal of Cell Science. 117, Pt 26, p. 6275-87 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments

Trucco, A., Polishchuk, R. S., Martella, O., Di Pentima, A., Fusella, A., Di Giandomenico, D., San Pietro, E., Beznoussenko, G. V., Polishchuk, E. V., Baldassarre, M., Buccione, R., Geerts, W. J. C., Koster, A. J., Burger, K. N. J., Mironov, A. A. & Luini, A., Nov 2004, In : Nature Cell Biology. 6, 11, p. 1071-81 11 p.

Research output: Contribution to journalArticle

231 Citations (Scopus)

The role of dynamin in the assembly and function of podosomes and invadopodia

McNiven, M. A., Baldassarre, M. & Buccione, R., 1 May 2004, In : Frontiers in Bioscience. 9, p. 1944-53 10 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)
2003

Dynamin participates in focal extracellular matrix degradation by invasive cells

Baldassarre, M., Pompeo, A., Beznoussenko, G., Castaldi, C., Cortellino, S., McNiven, M. A., Luini, A. & Buccione, R., Mar 2003, In : Molecular Biology of the Cell. 14, 3, p. 1074-84 11 p.

Research output: Contribution to journalArticle

159 Citations (Scopus)
2000

Regulation of protein sorting at the TGN by plasma membrane receptor activation

Baldassarre, M., Dragonetti, A., Marra, P., Luini, A., Isidoro, C. & Buccione, R., Feb 2000, In : Journal of Cell Science. 113 ( Pt 4), p. 741-8 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The lysosomal protease cathepsin D is efficiently sorted to and secreted from regulated secretory compartments in the rat basophilic/mast cell line RBL

Dragonetti, A., Baldassarre, M., Castino, R., Démoz, M., Luini, A., Buccione, R. & Isidoro, C., Sep 2000, In : Journal of Cell Science. 113 ( Pt 18), p. 3289-98 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
1999

Cyclosporin A, but not FK506, increases arachidonic acid release and inhibits proliferation of pituitary corticotrope tumor cells

Pompeo, A., Baldassarre, M., Luini, A., Buccione, R. & Baldassarre, M., 1999, In : Life Sciences. 64, 10, p. 837-46 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Morphological and biochemical analysis of the secretory pathway in melanoma cells with distinct metastatic potential

Ayala, I., Babià, T., Baldassarre, M., Pompeo, A., Fabra, A., Kok, J. W., Luini, A., Buccione, R. & Egea, G., 28 May 1999, In : FEBS Letters. 451, 3, p. 315-20 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
1998

Procollagen traverses the Golgi stack without leaving the lumen of cisternae: evidence for cisternal maturation

Bonfanti, L., Mironov, A. A., Martínez-Menárguez, J. A., Martella, O., Fusella, A., Baldassarre, M., Buccione, R., Geuze, H. J., Mironov, A. A. & Luini, A., 23 Dec 1998, In : Cell. 95, 7, p. 993-1003 11 p.

Research output: Contribution to journalArticle

300 Citations (Scopus)
1997

Neutrophil extracted lipocortin inhibits corticotropin secretion in the AtT-20 D16:16 clonal mouse pituitary cell line. Lipocortin inhibition of ACTH release in vitro

Pompeo, A., Luini, A., Hirata, F., Baldassarre, M. & Buccione, R., 31 Oct 1997, In : Regulatory Peptides. 72, 2-3, p. 169-77 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
1996

Regulation of constitutive exocytic transport by membrane receptors. A biochemical and morphometric study

Buccione, R., Bannykh, S., Santone, I., Baldassarre, M., Facchiano, F., Bozzi, Y., Di Tullio, G., Mironov, A., Luini, A. & De Matteis, M. A., 16 Feb 1996, In : The Journal of Biological Chemistry. 271, 7, p. 3523-33 11 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)