Research output per year
Research output per year
- 11 results
Search results
-
2018
Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)
Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In: Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)13 Downloads (Pure) -
2017
Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking
Al-Hilaly, Y. K., Pollack, S. J., Vadukul, D., Citossi, F., Rickard, J. E., Simpson, M., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 24 Nov 2017, In: Journal of Molecular Biology. 429, 23, p. 3650-3665 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Citations (Scopus)20 Downloads (Pure) -
2015
Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease
Harrington, C. R., Storey, J. M. D., Clunas, S., Harrington, K. A., Horsley, D., Ishaq, A., Kemp, S. J., Larch, C. P., Marshall, C., Nicoll, S. L., Rickard, J. E., Simpson, M., Sinclair, J. P., Storey, L. J. & Wischik, C. M., 24 Apr 2015, In: The Journal of Biological Chemistry. 290, 17, p. 10862-10875 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Citations (Scopus)16 Downloads (Pure) -
2012
New phenothiazine diaminium compounds are tau protein aggregation inhibitors, useful to treat e.g. Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia and frontotemporal lobar degeneration syndromes
Baddeley, T., Clunas, S., Harrington, C. R., Horsley, D., Ishaq, A., Khan, K., Loh, Y. S., Marshall, C., Rickard, J. E., Simpson, M., Sinclair, J. P., Storey, J. M. D., Williamson, C., Wischik, C. M. & Wood, B. A., 16 Aug 2012, Patent No. WO2012107706-A1, Priority date 11 Feb 2011Research output: Patent
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2011
Development of 18F-fluorinatable dendrons and their application to cancer cell targeting
Trembleau, L., Simpson, M., Cheyne, R. W., Escofet, I., Appleyard, M. V. C. L., Murray, K., Sharp, S., Thompson, A. M. & Smith, T. A. D., Nov 2011, In: New Journal of Chemistry. 35, 11, p. 2496-2502 7 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
18F-PEG-biotin: Precursor (boroaryl-PEG-biotin) synthesis, 18F-labelling and an in-vitro assessment of its binding to NeutravidinTM -trastuzumab pre-treated cells
Smith, T. A. D., Simpson, M., Cheyne, R. W. & Trembleau, L. A. C., Oct 2011, In: Applied Radiation and Isotopes. 69, 10, p. 1395-1400 6 p.Research output: Contribution to journal › Article › peer-review
File10 Citations (Scopus)7 Downloads (Pure) -
One-pot production of 18F-biotin by conjugation with 18F-FDG for pre-targeted imaging: Synthesis and radio-labelling of a PEGylated precursor
Simpson, M., Trembleau, L. A. C., Cheyne, R. W. & Smith, T. A. D., Feb 2011, In: Applied Radiation and Isotopes. 69, 2, p. 418-422 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)7 Downloads (Pure) -
2010
Materials and methods for medical imaging
Smith, T. A. D., Trembleau, L. A. C., McLaughlin, A. & Simpson, M., 2010, IPC No. WO2009056837, Patent No. GB2467494 (A)Research output: Patent
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2004
Diethyl 9,10-endo-ethano-9,10-dihydroanthracene-11,11-dicarboxylate
Simpson, M., Storey, J. M. D. & Harrison, W. T. A., 2004, In: Acta Crystallographica Section E: Structure Reports Online. E60, p. o1081-o1083 3 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
RbZrOAsO4: a zirconium-containing analogue of potassium titanyl phosphate (KTiOPO4)
Simpson, M. & Harrison, W. T. A., 2004, In: Solid State Sciences. 6, p. 981-985 5 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
2002
New Molecular Perovskites: Cubic C4N2H12·NH4Cl3.H2O and 2-H Hexagonal C6N2H14·NH4Cl3
Bremner, C. A., Simpson, M. & Harrison, W. T. A., 2002, In: Journal of the American Chemical Society. 124, 37, p. 10960-10961 1 p.Research output: Contribution to journal › Article › peer-review
70 Citations (Scopus)