• 1001 Citations
20102018

Research output per year

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Research Output

  • 1001 Citations
  • 13 Article
  • 1 Chapter
2018

mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol

González-García, I., Martinez de Morentin, P. B., Estévez-Salguero, Á., Contreras, C., Romero-Picó, A., Fernø, J., Nogueiras, R., Diéguez, C., Tena-Sempere, M., Tovar, S. & López, M., Sep 2018, In : Journal of Endocrinology. 238, 3, p. 177-186 9 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)

Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake

d'Agostino, G., Lyons, D., Cristiano, C., Lettieri, M., Olarte-Sanchez, C., Burke, L. K., Greenwald-Yarnell, M., Cansell, C., Doslikova, B., Georgescu, T., Blanco Martinez de Morentin, P., Myers Jr., M. G., Rochford, J. J. & Heisler, L., 2 Oct 2018, In : Cell Metabolism. 28, 4, p. 619.-630.e5 18 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
7 Downloads (Pure)
2017

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

Martínez-Sánchez, N., Seoane-Collazo, P., Contreras, C., Varela, L., Villarroya, J., Rial-Pensado, E., Buqué, X., Aurrekoetxea, I., Delgado, T. C., Vázquez-Martínez, R., González-García, I., Roa, J., Whittle, A. J., Gomez-Santos, B., Velagapudi, V., Tung, Y. C. L., Morgan, D. A., Voshol, P. J., Martínez de Morentin, P. B., López-González, T. & 21 others, Liñares-Pose, L., Gonzalez, F., Chatterjee, K., Sobrino, T., Medina-Gómez, G., Davis, R. J., Casals, N., Orešič, M., Coll, A. P., Vidal-Puig, A., Mittag, J., Tena-Sempere, M., Malagón, M. M., Diéguez, C., Martínez-Chantar, M. L., Aspichueta, P., Rahmouni, K., Nogueiras, R., Sabio, G., Villarroya, F. & López, M., 5 Jul 2017, In : Cell Metabolism. 26, 1, p. 212-229 17 p.

Research output: Contribution to journalArticle

Open Access
File
77 Citations (Scopus)
7 Downloads (Pure)

Lorcaserin improves glycemic control via a melanocortin neurocircuit

Burke, L. K., Ogunnowo-Bada, E., Georgescu, T., Cristiano, C., Martinez De Morentin, P. B., Valencia-Torres, L., D'Agostino, G., Riches, C., Heeley, N., Ruan, Y., Rubinstein, M., Low, M. J., Myers, M. G., Rochford, J. J., Evans, M. L. & Heisler, L. K., Oct 2017, In : Molecular Metabolism. 6, 10, p. 1092-1102 11 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
10 Downloads (Pure)
2016

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Yavari, A., Stocker, C. J., Ghaffari, S., Wargent, E. T., Steeples, V., Czibik, G., Pinter, K., Bellahcene, M., Woods, A., Martínez de Morentin, P. B., Cansell, C., Lam, B. Y. H., Chuster, A., Petkevicius, K., Nguyen-Tu, M-S., Martinez-Sanchez, A., Pullen, T. J., Oliver, P. L., Stockenhuber, A., Nguyen, C. & 34 others, Lazdam, M., O'Dowd, J. F., Harikumar, P., Tóth, M., Beall, C., Kyriakou, T., Parnis, J., Sarma, D., Katritsis, G., Wortmann, D. D. J., Harper, A. R., Brown, L. A., Willows, R., Gandra, S., Poncio, V., de Oliveira Figueiredo, M. J., Qi, N. R., Peirson, S. N., McCrimmon, R. J., Gereben, B., Tretter, L., Fekete, C., Redwood, C., Yeo, G. S. H., Heisler, L. K., Rutter, G. A., Smith, M. A., Withers, D. J., Carling, D., Sternick, E. B., Arch, J. R. S., Cawthorne, M. A., Watkins, H. & Ashrafian, H., 10 May 2016, In : Cell Metabolism. 23, 5, p. 821-836 16 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
6 Downloads (Pure)

Molecular mechanisms of appetite and obesity: a role for brain AMPK

Martínez de Morentin, P. B., Urisarri, A., Couce, M. L. & López, M., 1 Oct 2016, In : Clinical Science. 130, 19, p. 1697-709 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

Burke, L. K., Doslikova, B., D'Agostino, G., Greenwald-Yarnell, M., Georgescu, T., Chianese, R., Martinez de Morentin, P. B., Ogunnowo-Bada, E., Cansell, C., Valencia-Torres, L., Garfield, A. S., Apergis-Schoute, J., Lam, D. D., Speakman, J. R., Rubinstein, M., Low, M. J., Rochford, J. J., Myers, M. G., Evans, M. L. & Heisler, L. K., Mar 2016, In : Molecular Metabolism. 5, 3, p. 245-252 8 p.

Research output: Contribution to journalArticle

Open Access
File
38 Citations (Scopus)
8 Downloads (Pure)
2015

Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats

Martínez de Morentin, P. B., Lage, R., González-García, I., Ruíz-Pino, F., Martins, L., Fernández-Mallo, D., Gallego, R., Fernø, J., Señarís, R., Saha, A. K., Tovar, S., Diéguez, C., Nogueiras, R., Tena-Sempere, M. & López, M., Mar 2015, In : Endocrinology. 156, 3, p. 947-960 14 p.

Research output: Contribution to journalArticle

Open Access
36 Citations (Scopus)
2014

Hypothalamic mTOR: the rookie energy sensor

Martínez de Morentin, P. B., Martinez-Sanchez, N., Roa, J., Ferno, J., Nogueiras, R., Tena-Sempere, M., Dieguez, C. & Lopez, M., Jan 2014, In : Current molecular medicine. 14, 1, p. 3-21 19 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats

Seoane-Collazo, P., Martinez De Morentin, P. B., Ferno, J., Dieguez, C., Nogueiras, R. & Lopez, M., May 2014, In : Endocrinology. 155, 5, p. 1679-1689 11 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2013

Ghrelin, Lipid Metabolism, and Metabolic Syndrome

Blanco Martinez de Morentin, P., Tovar, S., Nogueiras, R., Lopez, M. & Diéguez, C., 15 Nov 2013, Metabolic Syndrome and Neurological Disorders. Farooqui, A. A. & Farooqui, T. (eds.). Wiley-Blackwell , p. 475-484 10 p. 29

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Hyperthyroidism differentially regulates neuropeptide S system in the rat brain

González, C. R., Martínez de Morentin, P. B., Martínez-Sánchez, N., Gómez-Díaz, C., Lage, R., Varela, L., Diéguez, C., Nogueiras, R., Castaño, J. P. & López, M., 23 Apr 2012, In : Brain Research. 1450, p. 40-48 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase

Martinez De Morentin, P. B., Whittle, A. J., Fernø, J., Nogueiras, R., Diéguez, C., Vidal-Puig, A. & López, M., Apr 2012, In : Diabetes. 61, 4, p. 807-817 11 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)
2010

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

López, M., Varela, L., Vázquez, M. J., Rodríguez-Cuenca, S., González, C. R., Velagapudi, V. R., Morgan, D. A., Schoenmakers, E., Agassandian, K., Lage, R., Martínez de Morentin, P. B., Tovar, S., Nogueiras, R., Carling, D., Lelliott, C., Gallego, R., Oresic, M., Chatterjee, K., Saha, A. K., Rahmouni, K. & 2 others, Diéguez, C. & Vidal-Puig, A., Sep 2010, In : Nature Medicine. 16, 9, p. 1001-1008 8 p.

Research output: Contribution to journalArticle

426 Citations (Scopus)