• 5717 Citations
20002020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020
Open Access
File
2 Downloads (Pure)
2019

A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor

Khatib, T., Whiting, A., Chisholm, D. R., Redfern, C., Muller, B. & McCaffery, P., Oct 2019, In : Molecular Neurobiology. 56, 10, p. 7074-7084 11 p.

Research output: Contribution to journalArticle

Open Access
File
3 Downloads (Pure)

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In : Cell Communication and Signaling. 17, 16 p., 40.

Research output: Contribution to journalArticle

Open Access
File
7 Downloads (Pure)

Highly Sensitive Quantitative Determination of Retinoic Acid Levels, Retinoic Acid Synthesis, and Catabolism in Embryonic Tissue Using a Reporter Cell-Based Method

Lee, L. M. Y., Tam, S. T. K., McCaffery, P. J. & Shum, A. S. W., 30 Jul 2019, Retinoid and Rexinoid Signaling. Ray, S. K. (ed.). HUMANA PRESS INC, Vol. 2019. p. 181-192 12 p. (Methods in Molecular Biology; vol. 2019).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Rapid Action of Retinoic Acid on the Hypothalamic Pituitary Adrenal Axis

Imoesi, P. I., Bowman, E. E., Stoney, P. N., Matz, S. & McCaffery, P., 30 Oct 2019, In : Frontiers in Neuroscience. 12, 8 p., 259.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
6 Downloads (Pure)

Synthetic Retinoids for Use in RAR Mediated Conditions

Whiting, A., Chisholm, D., Valentine, R., Greig, I. R., McCaffery, P. J. A. & Alkhatib, T., 18 Apr 2019, IPC No. C07C 63/66, A61K 31/192, A61K 31/203, A61P 25/28, C07D 209/82, C07D 215/06, European Patent Office, Patent No. WO2017174999, Priority date 6 Apr 2017, Priority No. 2017050977

Research output: Patent

2018

Neurogenesis in Response to Synthetic Retinoids at Different Temporal Scales

Haffez, H., Khatib, T., McCaffery, P., Przyborski, S., Redfern, C. & Whiting, A., Mar 2018, In : Molecular Neurobiology. 55, 3, p. 1942-1950 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
8 Downloads (Pure)

Rhythmic Diurnal Synthesis and Signaling of Retinoic Acid in the Rat Pineal Gland and Its Action to Rapidly Downregulate ERK Phosphorylation

Ashton, A., Stoney, P. N., Ransom, J. & McCaffery, P., Nov 2018, In : Molecular Neurobiology. 55, 11, p. 8219-8235 16 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
4 Downloads (Pure)
2017

A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways

Stoney, P. N., Rodrigues, D., Helfer, G., Khatib, T., Ashton, A., Hay, E. A., Starr, R., Kociszewska, D., Morgan, P. & McCaffery, P., Mar 2017, In : Brain, Behavior, and Immunity. 61, p. 340-352 13 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
12 Downloads (Pure)

Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes

Lee, L. M. Y., Leung, M. B. W., Kwok, R. C. Y., Leung, Y-C., Wang, C-C., McCaffery, P. J., Copp, A. J. & Shum, A. S. W., Apr 2017, In : Diabetes. 66, 4, p. 1041-1051 11 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
4 Downloads (Pure)

Synthetic retinoids for use in RAR mediated conditions

Greig, I. R., McCaffery, P. J. A., Whiting, A., Valentine, R., Chisholm, D. & Khatib, T., 12 Oct 2017, Patent No. WO2017174999

Research output: Patent

2016
Open Access
File
12 Citations (Scopus)
12 Downloads (Pure)

A Vitamin on the Mind: New Discoveries on Control of the Brain by Vitamin A

Stoney, P. N. & McCaffery, P., 2016, In : World Review in Nutrition and Dietetics. 115, p. 98-108 11 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
6 Downloads (Pure)

Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis

Stoney, P. N., Fragoso, Y., Bu Saeed, R., Ashton, A., Goodman, T., Simons, C., Gomaa, M. S., Sementilli, A., Sementilli, L., Ross, A. W., Morgan, P. J. & McCaffery, P. J., Jul 2016, In : Brain Structure and Function. 221, 6, p. 3315-3326 12 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
7 Downloads (Pure)

Targeting Retinoid Receptors to Treat Schizophrenia: Rationale and Progress to Date

Lerner, V., McCaffery, P. J. A. & Ritsner, M. S., 1 Apr 2016, In : CNS Drugs. 30, 4, p. 269-280 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Thyroid hormone activation of retinoic acid synthesis in hypothalamic tanycytes

Stoney, P. N., Helfer, G., Rodrigues, D., Morgan, P. J. & McCaffery, P., Mar 2016, In : Glia. 64, 3, p. 425-439 15 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
8 Downloads (Pure)
2015

Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders

Fragoso, Y. D., Stoney, P. N., Shearer, K. D., Sementilli, A., Nanescu, S. E., Sementilli, P. & McCaffery, P., Mar 2015, In : Brain Structure and Function. 220, 2, p. 1195-1203 9 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
5 Downloads (Pure)

Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen-signaling

Shearer, K. D., Morrice, N., Henderson, C., Reekie, J., McIlroy, G. D., McCaffery, P. J., Delibegovic, M. & Mody, N., Aug 2015, In : Obesity. 23, 8, p. 1655-1662 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Investigating the role of vitamin A in melatonin production in the pineal gland

Ashton, A. J., Stoney, P. N. & McCaffery, P. J., 2015, In : Proceedings of the Nutrition Society. 74, OCE3, p. E195-E195 1 p.

Research output: Contribution to journalAbstract

Retinoid Signaling in the Central Nervous System

Mccaffery, P. & Krezel, W., 12 Jun 2015, The Retinoids: Biology, Biochemistry, and Disease. Dolle, P. & Niederreither, K. (eds.). WILEY-BLACKWELL, p. 421-448 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
2014

The Evidence for a Beneficial Role of Vitamin A in Multiple Sclerosis

Fragoso, Y. D., Stoney, P. N. & McCaffery, P. J., Apr 2014, In : CNS Drugs. 28, 4, p. 291-299 9 p.

Research output: Contribution to journalLiterature review

22 Citations (Scopus)
11 Downloads (Pure)

The Expression and Roles of Nde1 and Ndel1 in the Adult Mammalian Central Nervous System

Pei, Z., Lang, B., Fragoso, Y. D., Shearer, K. D., Zhao, L., McCaffery, P. J. A., Shen, S., Ding, Y. Q., McCaig, C. D. & Collinson, J. M., 20 Jun 2014, In : Neuroscience. 271, p. 119-136 18 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
5 Downloads (Pure)

The rhythm of retinoids in the brain

Ransom, J., Morgan, P. J., McCaffery, P. J. & Stoney, P. N., May 2014, In : Journal of Neurochemistry. 129, 3, p. 366-376 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
28 Citations (Scopus)
53 Downloads (Pure)
2013
Open Access
File
30 Citations (Scopus)
5 Downloads (Pure)
2012

A paradoxical teratogenic mechanism for retinoic acid

Lee, L. M. Y., Leung, C-Y., Tang, W. W. C., Choi, H-L., Leung, Y-C., McCaffery, P. J., Wang, C-C., Woolf, A. S. & Shum, A. S. W., 21 Aug 2012, In : PNAS. 109, 34, p. 13668-13673 6 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Astrocytes as a regulated source of retinoic acid for the brain

Shearer, K. D., Fragoso, Y. D., Clagett-Dame, M. & McCaffery, P. J., Dec 2012, In : Glia. 60, 12, p. 1964-1976 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

A vitamin for the brain

Shearer, K. D., Stoney, P. N., Morgan, P. J. & McCaffery, P. J., Dec 2012, In : Trends in Neurosciences. 35, 12, p. 733-741 9 p.

Research output: Contribution to journalLiterature review

67 Citations (Scopus)

High expression of retinoic acid receptors and synthetic enzymes in the human hippocampus

Fragoso, Y. D., Shearer, K. D., Sementilli, A., de Carvalho, L. V. & McCaffery, P. J., Apr 2012, In : Brain Structure and Function. 217, 2, p. 473-483 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Influence of isotretinoin on hippocampal-based learning in human subjects

Ormerod, A., Thind, C. K., Rice, S. A., Reid, I. C., Williams, J. H. G. & McCaffery, P. J. A., Jun 2012, In : Psychopharmacology. 221, 4, p. 667-674 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Patterning of retinoic acid signaling and cell proliferation in the hippocampus

Goodman, T., Crandall, J. E., Nanescu, S. E., Quadro, L., Shearer, K., Ross, A. & McCaffery, P., Nov 2012, In : Hippocampus. 22, 11, p. 2171-2183 13 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Photoperiodic Expression of Two RALDH Enzymes and the Regulation of Cell Proliferation by Retinoic Acid in the Rat Hypothalamus

Shearer, K. D., Stoney, P. N., Nanescu, S. E., Helfer, G., Barrett, P., Ross, A. W., Morgan, P. J. & McCaffery, P., Aug 2012, In : Journal of Neurochemistry. 122, 4, p. 789-799 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Photoperiod regulates vitamin A and Wnt/β-catenin signaling in F344 rats

Helfer, G., Ross, A. W., Russell, L., Thomson, L. M., Shearer, K. D., Goodman, T. H., McCaffery, P. J. & Morgan, P. J., 1 Feb 2012, In : Endocrinology. 153, 2, p. 815-824 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2011

Positive effects of isotretinoin on cognition learning and memory

Ormerod, A. D., Thind, C., Rice, S., Williams, J. H. G. & McCaffery, P. J. A., Jul 2011, In : British Journal of Dermatology. 165, S1, p. 3-4 2 p.

Research output: Contribution to journalSpecial issue

Retinoic acid and affective disorders: the evidence for an association

Bremner, J. D., Shearer, K. D. & McCaffery, P. J., 2011, In : Journal of Clinical Psychiatry. 73, 1, p. 37-50 14 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex

Crandall, J. E., Goodman, T., McCarthy, D. M., Duester, G., Bhide, P. G., Draeger, U. C. & McCaffery, P., Nov 2011, In : Journal of Neurochemistry. 119, 4, p. 723-735 13 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2010

HPLC/MS(N) analysis of retinoids

Evans, J. E. & McCaffery, P., May 2010, In : Methods in Molecular Biology. 652, p. 149-162 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Photoperiodic regulation of retinoic acid signaling in the hypothalamus

Shearer, K. D., Goodman, T. H., Ross, A., Reilly, L., Morgan, P. J. & McCaffery, P. J. A., Jan 2010, In : Journal of Neurochemistry. 112, 1, p. 246-257 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Vulnerability of the brain to neuropsychiatric disorders resulting from abnormal thyroid hormone or vitamin D homeostasis

Bailey, S. J. & McCaffery, P. J., 1 Jan 2010, Brain Protection in Schizophrenia, Mood and Cognitive Disorders. Ritsner, M. S. (ed.). Springer Netherlands, p. 105-133 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)
2009

Restricted patterns of Hoxd10 and Hoxd11 set segmental differences in motoneuron subtype complement in the lumbosacral spinal cord

Misra, M., Shah, V., Carpenter, E., McCaffery, P. & Lance-Jones, C., 1 Jun 2009, In : Developmental Biology. 330, 1, p. 54-72 19 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Retinoic Acid Signalling in Neuropsychiatric Disease: Possible Markers and Treatment Agents

Bailey, S. J. & McCaffery, P. J., 25 May 2009, The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes: Volume III: Metabolic and Peripheral Biomarkers. Ritsner, M. (ed.). Dordrecht, Netherlands: Springer Science+Business Media, Vol. 3. p. 171-190 20 p. (The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingChapter

2008

Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

Silvestri, C., Narimatsu, M., von Both, I., Liu, Y., Tan, N. B. J., Izzi, L., McCaffery, P., Wrana, J. L. & Attisano, L., 11 Mar 2008, In : Developmental Cell. 14, 3, p. 411-423 13 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid

Spiegl, N., Didichenko, S., McCaffery, P., Langen, H. & Dahinden, C. A., 1 Nov 2008, In : Blood. 112, 9, p. 3762-3771 10 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2007

Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury

Kern, J., Schrage, K., Koopmans, G. C., Joosten, E. A., McCaffery, P. & Mey, J., Feb 2007, In : International Journal of Developmental Neuroscience. 25, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Enhancement of brain retinoic acid levels

Goodman, A. B., McCaffery, P. J. A., Palha, J. A., Simons, C. & Pardee, A. B., 3 Dec 2007, Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies . Smith, H. J., Simons, C. & Sewell, R. D. E. (eds.). Boca Raton, FL, USA: CRC Press, p. 337-378 42 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Prospective teratology of retinoic acid metabolic blocking agents (RAMBAs) and loss of CYP26 activity

McCaffery, P. & Simons, C., Oct 2007, In : Current Pharmaceutical Design. 13, 29, p. 3020-3037 18 p.

Research output: Contribution to journalLiterature review

21 Citations (Scopus)
2006

Defects in tangential neuronal migration of pontine nuclei neurons in the Largemyd mouse are associated with stalled migration in the ventrolateral hindbrain

Qu, Q., Crandall, J. E., Luo, T., McCaffery, P. J. & Smith, F. I., 1 Jun 2006, In : European Journal of Neuroscience. 23, 11, p. 2877-2886 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Retinoic acid regulates neurogenesis in the hippocampus: Possible consequences for depression

McCaffery, P. J. A., Jul 2006, In : International Journal of Neuropsychopharmacology. 9, Supplement 1, p. S79-S80 2 p.

Research output: Contribution to journalSpecial issue

Retinoic acid signaling and function in the adult hippocampus

McCaffery, P., Zhang, J. & Crandall, J. E., Jun 2006, In : Journal of Neurobiology. 66, 7, p. 780-791 12 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
2005

Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain

Tse, S-W., Broderick, J. A., Wei, M-L., Luo, M-H., Smith, D., McCaffery, P. J. A., Stamm, S. & Andreadis, A., 10 Oct 2005, In : Gene. 359, p. 63-72 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)