Petra Gisela Helen Louis

Dr

    • AB25 2ZD

    • 10179 Citations
    19942019
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    Research Output 1994 2019

    2019

    Flintibacter

    Louis, P., Lo, G., Kramer, T. & Duncan, S., 22 May 2019, (Accepted/In press) Bergey’s Manual of Systematics of Archaea and Bacteria. Wiley

    Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

    1 Citation (Scopus)
    6 Downloads (Pure)
    Open Access
    File
    formic acid
    Ruminococcus bromii
    formates
    coculture
    Coculture Techniques
    1 Citation (Scopus)

    Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation

    Dimidi, E., Zdanaviciene, A., Christodoulides, S., Taheri, S., Louis, P., Duncan, P. I., Emami, N., Crabbé, R., De Castro, C. A., McLean, P., Bergonzelli, G. E., Whelan, K. & Mark Scott, S., 28 Feb 2019, In : Alimentary Pharmacology & Therapeutics. 49, 3, p. 251-264 14 p.

    Research output: Contribution to journalArticle

    Probiotics
    Constipation
    Microbiology
    Randomized Controlled Trials
    Placebos
    2 Citations (Scopus)
    4 Downloads (Pure)

    The effect of prunes on stool output, gut transit time and gastrointestinal microbiota: a randomised controlled trial

    Lever, E., Scott, S. M., Louis, P., Emery, P. W. & Whelan, K., Feb 2019, In : Clinical Nutrition. 38, 1, p. 165-173 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Volatile Fatty Acids
    Randomized Controlled Trials
    Weights and Measures
    Water
    Flatulence
    2018
    3 Citations (Scopus)
    3 Downloads (Pure)

    Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition

    Drew, J. E., Reichardt, N., Williams, L. M., Mayer, C-D., Walker, A. W., Farquharson, A. J., Kastora, S., Farquharson, F., Milligan, G., Morrison, D. J., Preston, T., Flint, H. J. & Louis, P., 22 Oct 2018, In : Scientific Reports. 8, 15566.

    Research output: Contribution to journalArticle

    Open Access
    File
    Inulin
    Cecum
    Dietary Fiber
    Obesity
    Esters
    2 Citations (Scopus)
    8 Downloads (Pure)

    microPop: modelling microbial populations and communities in R

    Kettle, H., Holtrop, G., Louis, P. G. H. & Flint, H. J., Feb 2018, In : Methods in Ecology and Evolution. 9, 2, p. 399-409 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    functional group
    parameter uncertainty
    bacteriophage
    ecosystem function
    dynamic models
    5 Citations (Scopus)
    3 Downloads (Pure)

    Mutual Interaction of Phenolic Compounds and Microbiota: Metabolism of Complex Phenolic Apigenin-C- and Kaempferol-O-Derivatives by Human Fecal Samples

    Vollmer, M., Esders, S., Farquharson, F. M., Neugart, S., Duncan, S., Schreiner, M., Louis, P., Maul, R. & Rohn, S., 17 Jan 2018, In : Journal of Agricultural and Food Chemistry. 66, 2, p. 485–497 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Apigenin
    apigenin
    Microbiota
    kaempferol
    Metabolism
    4 Citations (Scopus)
    6 Downloads (Pure)

    Porcine small and large intestinal microbiota rapidly hydrolyze the masked mycotoxin deoxynivalenol-3-glucoside and release deoxynivalenol in spiked batch cultures in vitro

    Gratz, S., Currie, V., Richardson, A., Duncan, G., Holtrop, G., Farquharson, F., Louis, P., Pinton, P. & Oswald, I. P., Jan 2018, In : Applied and Environmental Microbiology. 84, 2, p. 1-9 9 p., 02106-17.

    Research output: Contribution to journalArticle

    Open Access
    File
    deoxynivalenol-3-glucoside
    Batch Cell Culture Techniques
    Mycotoxins
    deoxynivalenol
    intestinal microorganisms
    17 Citations (Scopus)
    10 Downloads (Pure)

    Specific substrate-driven changes in human faecal microbiota composition contrast with functional redundancy in short-chain fatty acid production

    Reichardt, N., Vollmer, M., Holtrop, G., Farquharson, F. M., Wefers, D., Bunzel, M., Duncan, S. H., Drew, J. E., Williams, L. M., Milligan, G., Preston, T., Morrison, D., Flint, H. J. & Louis, P., 2018, In : The ISME Journal. 12, p. 610-622 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Volatile Fatty Acids
    Butyrates
    Microbiota
    short chain fatty acids
    butyrates
    12 Citations (Scopus)
    9 Downloads (Pure)

    Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

    Mukhopadhya, I., Morais, S., Laverde-Gomez, J., Sheridan, P. O., Walker, A. W., Kelly, W., Klieve, A. V., Ouwerkerk, D., Duncan, S. H., Louis, P., Koropatkin, N., Cockburn, D., Kibler, R., Cooper, P. J., Sandoval, C., Crost, E., Juge, N., Bayer, E. A. & Flint, H. J., Jan 2018, In : Environmental Microbiology. 20, p. 324-336 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Ruminococcus bromii
    Ruminococcus
    sporulation
    Rumen
    starch
    2017
    6 Citations (Scopus)
    3 Downloads (Pure)

    Chlorogenic acid versus amaranth's caffeoylisocitric acid – Gut microbial degradation of caffeic acid derivatives

    Vollmer, M., Schröter, D., Esders, S., Neugart, S., Farquharson, F. M., Duncan, S. H., Schreiner, M., Louis, P., Maul, R. & Rohn, S., Oct 2017, In : Food Research International. 100, 3, p. 375-384 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Chlorogenic Acid
    caffeic acid
    chlorogenic acid
    biodegradation
    intestinal microorganisms
    102 Citations (Scopus)
    4 Downloads (Pure)

    Diet Low in FODMAPs Reduces Symptoms in Patients with Irritable Bowel Syndrome and Probiotic Restores Bifidobacterium Species: a Randomized Controlled Trial

    Staudacher, HM., Lomer, MCE., Farquharson, FM., Louis, P., Fava, F., Franciosi, E., Scholz, M., Tuohy, KM., Lindsay, J. O., Irving, PM. & Whelan, K., Oct 2017, In : Gastroenterology. 153, 4, p. 936-947 12 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Bifidobacterium
    Irritable Bowel Syndrome
    Probiotics
    Randomized Controlled Trials
    Diet
    2 Citations (Scopus)
    4 Downloads (Pure)

    Different Substrate Preferences Help Closely Related Bacteria To Coexist in the Gut

    Louis, P., 7 Nov 2017, In : mBio. 8, 6, p. 1-4 4 p., e01824-17.

    Research output: Contribution to journalComment/debate

    Open Access
    File
    Polysaccharides
    Bacteria
    Food
    Bacteroides
    Coculture Techniques
    161 Citations (Scopus)
    7 Downloads (Pure)

    Formation of propionate and butyrate by the human colonic microbiota

    Louis, P. & Flint, H. J., Jan 2017, In : Environmental Microbiology. 19, 1, p. 29-41 13 p.

    Research output: Contribution to journalLiterature review

    Open Access
    File
    Volatile Fatty Acids
    Butyrates
    Microbiota
    Propionates
    short chain fatty acids
    33 Citations (Scopus)
    6 Downloads (Pure)

    Prebiotic potential of pectin and pectic oligosaccharides to promote anti-inflammatory commensal bacteria in the human colon

    Chung, W. S. F., Meijerink, M., Zeuner, B., Holck, J., Louis, P., Meyer, A. S., Wells, J. M., Flint, H. J. & Duncan, S. H., 1 Nov 2017, In : FEMS Microbiology Ecology. 93, 11, p. 1-9 9 p., fix127.

    Research output: Contribution to journalArticle

    Open Access
    File
    Prebiotics
    commensal
    Oligosaccharides
    Colon
    Anti-Inflammatory Agents
    34 Citations (Scopus)

    The impact of nutrition on intestinal bacterial communities

    Flint, H. J., Duncan, S. H. & Louis, P., Aug 2017, In : Current Opinion in Microbiology. 38, p. 59-65 7 p.

    Research output: Contribution to journalLiterature review

    Diet
    Microbiota
    Large Intestine
    Health
    Growth
    2016
    14 Citations (Scopus)
    7 Downloads (Pure)

    Extending colonic mucosal microbiome analysis - Assessment of colonic lavage as a proxy for endoscopic colonic biopsies

    Watt, E., Gemmell, M. R., Berry, S., Glaire, M., Farquharson, F., Louis, P., Murray, G. I., El-Omar, E. & Hold, G. L., 25 Nov 2016, In : Microbiome. 4, 61.

    Research output: Contribution to journalArticle

    Open Access
    File
    Therapeutic Irrigation
    Microbiota
    Proxy
    Biopsy
    Colonoscopy
    23 Citations (Scopus)

    How to Manipulate the Microbiota: Prebiotics

    Louis, P., Flint, H. J. & Michel, C., 2016, Microbiota of the Human Body: Implications in Health and Disease. Schwiertz, A. (ed.). Switzerland: Springer , p. 119-142 24 p. ( Advances in Experimental Medicine and Biology; vol. 902).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Prebiotics
    Microbiota
    Food
    Functional Food
    Disease Susceptibility
    107 Citations (Scopus)
    5 Downloads (Pure)

    Modulation of the human gut microbiota by dietary fibres occurs at the species level

    Chung, W. S. F., Walker, A. W., Louis, P., Parkhill, J., Vermeiren, J., Bosscher, D., Duncan, S. H. & Flint, H. J., 11 Jan 2016, In : BMC Biology. 14, 3.

    Research output: Contribution to journalArticle

    Open Access
    File
    Inulin
    Dietary Fiber
    intestinal microorganisms
    Prebiotics
    inulin
    2015
    10 Citations (Scopus)

    Essential oils have different effects on human pathogenic and commensal bacteria in mixed faecal fermentations compared to pure cultures

    Thapa, D., Louis, P., Losa, R., Zweifel, B. & Wallace, R. J., 1 Feb 2015, In : Microbiology . 161, 2, p. 441-449 9 p.

    Research output: Contribution to journalArticle

    Thymol
    Volatile Oils
    Clostridium difficile
    Fermentation
    Bacteria
    206 Citations (Scopus)

    Links between diet, gut microbiota composition and gut metabolism

    Flint, H. J., Duncan, S. H., Scott, K. P. & Louis, P., Feb 2015, In : Proceedings of the Nutrition Society. 74, 1, p. 13-22 10 p.

    Research output: Contribution to journalLiterature review

    Butyrates
    Microbiota
    Propionates
    Diet
    Lactic Acid
    45 Citations (Scopus)
    3 Downloads (Pure)

    Modelling the emergent dynamics and major metabolites of the human colonic microbiota

    Kettle, H., Louis, P. G. H., Holtrop, G., Duncan, S. H. & Flint, H. J., May 2015, In : Environmental Microbiology. 17, 5, p. 1615-1630 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Microbiota
    metabolite
    Colon
    metabolites
    colon
    47 Citations (Scopus)
    4 Downloads (Pure)

    Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii

    Ze, X., David, B., Laverde Gomez, J., Dassa, B., Sheridan, P. O., Duncan, S. H., Louis, P. G. H., Henrissat, B., Juge, N., Koropatkin, N. M., Bayer, E. A. & Flint, H. J., 29 Sep 2015, In : mBio. 6, 5, e01058-15.

    Research output: Contribution to journalArticle

    Open Access
    File
    Ruminococcus
    Amylases
    Starch
    Bacteria
    Proteins
    2014
    54 Citations (Scopus)

    Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings

    Hedin, C. R., McCarthy, N. E., Louis, P., Farquharson, F. M., McCartney, S., Taylor, K., Prescott, N. J., Murrells, T., Stagg, A. J., Whelan, K. & Lindsay, J. O., Oct 2014, In : Gut. 63, 10, p. 1578-1586 9 p.

    Research output: Contribution to journalArticle

    Crohn Disease
    Siblings
    Blood Cells
    T-Lymphocytes
    Phenotype
    24 Citations (Scopus)
    Ruminococcus
    Firmicutes
    Glucans
    Microbiota
    glucans

    Faecal microbiota profiling in human volunteers on low and high fruit and vegetable intakes

    Farquharson, F. M., Ze, X., Scobbie, L., Milne, L., Duncan, S. H., Holtrop, G., Flint, H. J., Rungapamestry, V., Duthie, G. G., Bestwick, C. S., Duthie, S. J. & Louis, P. G., 2014, ROWETT-INRA 2014 Gut Microbiology: From Sequence to Function. Rowett Institute of Nutrition and Health, p. 116 1 p. P131

    Research output: Chapter in Book/Report/Conference proceedingOther contribution

    Functional metagenomics of human intestinal microbiome β-glucuronidase activity

    Louis, P. G. H. & Dore, J., 2014, Encyclopedia of Metagenomics. Nelson, K. E. (ed.). New York: Springer , p. 1-8 8 p. 349787

    Research output: Chapter in Book/Report/Conference proceedingChapter

    4 Citations (Scopus)

    Gut microbiome and obesity

    Flint, H. J., Duncan, S. H. & Louis, P. G. H., 2014, Treatment of the obese patient. Kushner, R. F. & Bessesen, D. H. (eds.). 2nd ed. London: Springer Science+Business Media, p. 73-82 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    174 Citations (Scopus)

    Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

    Salonen, A., Lahti, L., Salojärvi, J., Holtrop, G., Korpela, K., Duncan, S. H., Date, P., Farquharson, F., Johnstone, A. M., Lobley, G. E., Louis, P., Flint, H. J. & de Vos, W. M., Nov 2014, In : The ISME Journal. 8, 11, p. 2218-2230 13 p.

    Research output: Contribution to journalArticle

    individual variation
    intestinal microorganisms
    Microbiota
    Fermentation
    fermentation
    236 Citations (Scopus)

    Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

    Reichardt, N., Duncan, S. H., Young, P., Belenguer, A., McWilliam Leitch, C., Scott, K. P., Flint, H. J. & Louis, P., Jun 2014, In : The ISME Journal. 8, 6, p. 1323-1335 13 p.

    Research output: Contribution to journalArticle

    Propionates
    propionates
    intestinal microorganisms
    Coprococcus catus
    phylogenetics
    77 Citations (Scopus)

    Phylogeny, culturing, and metagenomics of the human gut microbiota

    Walker, A. W., Duncan, S. H., Louis, P. & Flint, H. J., May 2014, In : Trends in Microbiology. 22, 5, p. 267-274 8 p.

    Research output: Contribution to journalLiterature review

    Metagenomics
    Phylogeny
    Microbiota
    Research
    Databases

    SATIN (Satiety Innovation) Project: Impact of type 3 resistant starch on gut microbiota and metabolites in overweight human volunteers

    McKinnon, H., Romero Gonzalez, R. P. D. C., Fyfe, C. L., Whelan, A., Ze, X., Pesci, I., Farquharson, F. M., Louis, P. G. H., Bosscher, D., Bonnema, A., Ryan, S., Shirazi-Beechey, S. P., Harold, J., Halford, J. C. G., Duncan, S. H., Johnstone, A., Flint, H. J. & Gratz, S., 2014, ROWETT-INRA 2014 Gut Microbiology: From Sequence to Function. Rowett Institute of Nutrition and Health, p. 122-122 1 p. P143. (ROWETT-INRA Gut Microbiology).

    Research output: Chapter in Book/Report/Conference proceedingOther contribution

    628 Citations (Scopus)

    The gut microbiota, bacterial metabolites and colorectal cancer

    Louis, P., Hold, G. L. & Flint, H. J., Oct 2014, In : Nature Reviews Microbiology. 12, 10, p. 661-672 12 p.

    Research output: Contribution to journalLiterature review

    Colorectal Neoplasms
    Metabolome
    Volatile Fatty Acids
    Butyrates
    Propionates
    118 Citations (Scopus)
    3 Downloads (Pure)

    The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing

    Kennedy, N. A., Walker, A. W., Berry, S. H., Duncan, S. H., Farquarson, F. M., Louis, P., Thomson, J. M., Satsangi, J., Flint, H. J., Parkhill, J., Lees, C. W., Hold, G. L. & UK IBD Genetics Consortium, 24 Feb 2014, In : PloS ONE. 9, 2, e88982.

    Research output: Contribution to journalArticle

    Open Access
    File
    Bacterial Structures
    rRNA Genes
    intestinal microorganisms
    bacterial communities
    Genes
    2013
    2 Citations (Scopus)

    How our gut microbes influence our behaviour

    Louis, P. & Flint, HJ., May 2013, In : Journal of Neuroendocrinology. 25, 5, p. 517-518 2 p.

    Research output: Contribution to journalLetter

    42 Citations (Scopus)

    Intestinal colonization: how key microbial players become established in this dynamic process

    El Aidy, S., Van den Abbeele, P., Van de Wiele, T., Louis, P. & Kleerebezem, M., Oct 2013, In : BioEssays. 35, 10, p. 913-923 11 p.

    Research output: Contribution to journalLiterature review

    Metabolites
    Homeostasis
    Dysbiosis
    Microbial Interactions
    Microbiota
    49 Citations (Scopus)
    5 Downloads (Pure)

    Some are more equal than others: the role of ‘keystone’ species in the degradation of recalcitrant substrates

    Ze, X., Le Mougen, F., Duncan, S. H., Louis, P. & Flint, H. J., May 2013, In : Gut Microbes. 4, 3, p. 236-240 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Starch
    Ruminococcus
    Bacteria
    Large Intestine
    Rumen
    2012
    2 Citations (Scopus)

    Dietary modulation of the human gut microbiota

    Louis, P., Nov 2012, In : AGRO Food Industry Hi-Tech. 23, 6, p. 26-28 3 p.

    Research output: Contribution to journalLiterature review

    Microbiota
    intestinal microorganisms
    Modulation
    Carbohydrates
    Nutrition
    50 Citations (Scopus)

    Does the human gut microbiota contribute to the etiology of autism spectrum disorders?

    Louis, P., Aug 2012, In : Digestive Diseases and Sciences. 57, 8, p. 1987-1989 3 p.

    Research output: Contribution to journalEditorial

    497 Citations (Scopus)

    Microbial degradation of complex carbohydrates in the gut

    Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P. & Forano, E., 1 Jul 2012, In : Gut Microbes. 3, 4, p. 289-306 18 p.

    Research output: Contribution to journalLiterature review

    Dietary Carbohydrates
    Intestines
    Verrucomicrobia
    Carbohydrates
    Bacteroidetes
    152 Citations (Scopus)
    4 Downloads (Pure)

    Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

    Hansen, R., Russell, R. K., Reiff, C., Louis, P., McIntosh, F., Berry, S. H., Mukhopadhya, I., Bisset, W. M., Barclay, A. R., Bishop, J., Flynn, D. M., McGrogan, P., Loganathan, S., Mahdi, G., Flint, H. J., El-Omar, E. M. & Hold, G. L., 5 Dec 2012, In : American journal of gastroenterology. 107, 12, p. 1913-1922 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Microbiota
    Ulcerative Colitis
    Inflammatory Bowel Diseases
    Crohn Disease
    Pediatrics
    38 Citations (Scopus)

    Phylogenetic distribution of genes encoding β-glucuronidase activity in human colonic bacteria and the impact of diet on faecal glycosidase activities

    McIntosh, F. M., Maison, N., Holtrop, G., Young, P., Stevens, V. J., Ince, J., Johnstone, A. M., Lobley, G., Flint, H. J. & Louis, P., 2012, In : Environmental Microbiology. 14, 8, p. 1876-1887 12 p.

    Research output: Contribution to journalArticle

    glycosidases
    Glycoside Hydrolases
    Glucuronidase
    Human Activities
    diet
    285 Citations (Scopus)

    Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon

    Ze, X., Duncan, S. H., Louis, P. & Flint, H. J., 2012, In : The ISME Journal. 6, 8, p. 1535-1543 9 p.

    Research output: Contribution to journalArticle

    Ruminococcus bromii
    Ruminococcus
    keystone species
    resistant starch
    starch
    653 Citations (Scopus)

    The role of the gut microbiota in nutrition and health

    Flint, H. J., Scott, K. P., Louis, P. & Duncan, S. H., Oct 2012, In : Nature Reviews Gastroenterology & Hepatology. 9, 10, p. 577-589 13 p.

    Research output: Contribution to journalLiterature review

    Large Intestine
    Health
    Diet
    Gastrointestinal Diseases
    Microbiota
    2011
    43 Citations (Scopus)

    Butyrate production in phylogenetically diverse Firmicutes isolated from the chicken caecum

    Eeckhaut, V., Van Immerseel, F., Croubels, S., De Baere, S., Haesebrouck, F., Ducatelle, R., Louis, P. & Vandamme, P., Jul 2011, In : Microbial Biotechnology. 4, 4, p. 503-512 10 p.

    Research output: Contribution to journalArticle

    700 Citations (Scopus)

    Dominant and diet-responsive groups of bacteria within the human colonic microbiota

    Walker, A. W., Ince, J., Duncan, S. H., Webster, L., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., Louis, P., McIntosh, F., Johnstone, A. M., Lobley, G. E., Parkhill, J. & Flint, H. J., Feb 2011, In : The ISME Journal. 5, 2, p. 220-230 11 p.

    Research output: Contribution to journalArticle

    Impact of Intestinal Microbial Communities upon Health

    Flint, H. J., Duncan, S. H. & Louis, P., 2011, Beneficial microorganisms in multicellular life forms. Rosenberg, E. & Gophna, U. (eds.). Springer-Verlag, p. 243-252 252 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1 Citation (Scopus)

    Micro-organisms in the human gut: diversity and function

    Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., Aug 2011, In : The Biochemist. 33, 4, p. 4-9 5 p.

    Research output: Contribution to journalLiterature review

    Gastrointestinal Tract
    Health
    Chemical analysis
    Research
    20 Citations (Scopus)

    Nutritional influences on the gut microbiota and the consequences for gastrointestinal health

    Scott, K. P., Duncan, S. H., Louis, P. & Flint, H. J., 1 Aug 2011, In : Biochemical Society Transactions. 39, 4, p. 1073-1078 6 p.

    Research output: Contribution to journalLiterature review

    Health
    Lower Gastrointestinal Tract
    Upper Gastrointestinal Tract
    Microbiota
    Chemical analysis